Endothelial Mineralocorticoid Receptor Deletion Prevents Diet-Induced Cardiac Diastolic Dysfunction in Females

Hypertension

Volumn 66, Issue 6, 2015, Pages 1159-1167

  Jia, Guanghong ^a,c   Habibi, Javad ^a,c   DeMarco, Vincent G ^a,b,c   Martinez Lemus, Luis A ^b,c,d   Ma, Lixin ^a,c   Whaley Connell, Adam T ^a,c   Aroor, Annayya R ^a,c   Domeier, Timothy L ^b   Zhu, Yi ^d   Meininger, Gerald A ^b,d   Mueller, Katelee Barrett ^e   Jaffe, Iris Z ^e   Sowers, James R ^a,b,c,d  

^a University of Missouri   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d UNIVERSITY OF MISSOURI   (United States)

^e TUFTS MEDICAL CENTER   (United States)

Author keywords

cardiovascular diseases; diet, Western; insulin resistance; obesity; receptors, mineralocorticoid

Indexed keywords

CD11B ANTIGEN; CD86 ANTIGEN; CORN SYRUP; INTERLEUKIN 1; INTERLEUKIN 17; MINERALOCORTICOID RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MONOCYTE CHEMOTACTIC PROTEIN 1; S6 KINASE; S6 KINASE 1; SMAD PROTEIN; SUCROSE; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; AUTACOID; CYTOKINE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL STIFFNESS; ARTICLE; ATOMIC FORCE MICROSCOPY; BODY COMPOSITION; BODY FAT; BODY MASS; BODY WEIGHT; CARDITIS; CELL MOTION; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; ENDOTHELIUM CELL; ENZYME PHOSPHORYLATION; FEMALE; FIBROSING ALVEOLITIS; FOOD INTAKE; HEART LEFT VENTRICLE FILLING PRESSURE; HEART MUSCLE FIBROSIS; HYPERTROPHY; INSULIN METABOLISM; INSULIN SENSITIVITY; KNOCKOUT MOUSE; LEAN BODY WEIGHT; MACROPHAGE; MEAN ARTERIAL PRESSURE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RELAXATION TIME; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN DIET; WESTERN DIET INDUCED CARDIAC DIASTOLIC DYSFUNCTION; WILD TYPE MOUSE; ADVERSE EFFECTS; ANIMAL; CARDIAC MUSCLE; CARDIOMYOPATHIES; DEFICIENCY; DIASTOLE; FIBROSIS; GENETICS; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE HYPERTROPHY; INSULIN RESISTANCE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CARDIOMYOPATHIES; CYTOKINES; DIASTOLE; DIET, WESTERN; ENDOTHELIAL CELLS; FEMALE; FIBROSIS; HYPERTROPHY; HYPERTROPHY, LEFT VENTRICULAR; INFLAMMATION MEDIATORS; INSULIN RESISTANCE; MICE, KNOCKOUT; MYOCARDIUM; OXIDATIVE STRESS; PHOSPHATIDYLINOSITOL 3-KINASE; PHOSPHORYLATION; PROTEIN KINASES; RECEPTORS, MINERALOCORTICOID; SIGNAL TRANSDUCTION; VENTRICULAR DYSFUNCTION, LEFT;

EID: 84947487152     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.115.06015     Document Type: Article

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