Arterial expression of the calcium-sensing receptor is maintained by physiological pulsation and protects against calcification

PLoS ONE

Volumn 10, Issue 10, 2015, Pages

  Molostvov, Guerman ^a   Hiemstra, Thomas F ^b   Fletcher, Simon ^c   Bland, Rosemary ^d   Zehnder, Daniel ^b  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c ADDENBROOKE S HOSPITAL   (United Kingdom)

^d UNIVERSITY HOSPITALS COVENTRY AND WARWICKSHIRE NHS TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; CALCIUM ION; CALCIUM SENSING RECEPTOR; MESSENGER RNA; OSTEOCALCIN; SMALL INTERFERING RNA; TECALCET; TRANSCRIPTION FACTOR RUNX2; CALCIUM; CASR PROTEIN, HUMAN; DMP1 PROTEIN, HUMAN; HYBRID PROTEIN; N-(2-CHLOROPHENYLPROPYL)-1-(3-METHOXYPHENYL)ETHYLAMINE; PHENETHYLAMINE DERIVATIVE; PHOSPHOPROTEIN; PROPYLAMINE; RUNX2 PROTEIN, HUMAN; SCLEROPROTEIN;

ADULT; AGED; ANALYTICAL PARAMETERS; AORTIC SMOOTH MUSCLE CELL; ARTERIAL CYCLIC STRAIN; ARTERIAL HOMEOSTASIS; ARTICLE; BLOOD VESSEL CALCIFICATION; BLOOD VESSEL PARAMETERS; CALCIUM METABOLISM; CELL STIMULATION; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION REGULATION; GENE SILENCING; HOMEOSTASIS; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MOLECULAR DYNAMICS; MUSCULOSKELETAL FUNCTION; OSTEOCHONDROGENIC TRANSFORMATION; PHENOTYPE; PROPHYLAXIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PULSE WAVE; SMOOTH MUSCLE FIBER; TISSUE DISTRIBUTION; TOTAL ARTERY CALCIUM CONTENT; AGONISTS; ANTAGONISTS AND INHIBITORS; AORTA; BIOSYNTHESIS; BONE DEVELOPMENT; CELL CULTURE; CHONDROGENESIS; CYTOLOGY; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; MECHANICAL STRESS; METABOLISM; MIDDLE AGED; OSTEOBLAST; PATHOPHYSIOLOGY; PHYSIOLOGY; PULSATILE FLOW; SMOOTH MUSCLE CELL; VASCULAR CALCIFICATION; VASCULAR SMOOTH MUSCLE; YOUNG ADULT;

ADULT; AGED; AORTA; CALCIUM; CELLS, CULTURED; CHONDROGENESIS; CORE BINDING FACTOR ALPHA 1 SUBUNIT; EXTRACELLULAR MATRIX PROTEINS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; MALE; MIDDLE AGED; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; OSTEOBLASTS; OSTEOGENESIS; PHENETHYLAMINES; PHOSPHOPROTEINS; PROPYLAMINES; PULSATILE FLOW; RECEPTORS, CALCIUM-SENSING; RECOMBINANT FUSION PROTEINS; STRESS, MECHANICAL; TRANSFECTION; VASCULAR CALCIFICATION; YOUNG ADULT;

EID: 84947233282     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0138833     Document Type: Article

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