Calcimimetics increase CaSR expression and reduce mineralization in vascular smooth muscle cells: Mechanisms of action

Cardiovascular Research

Volumn 101, Issue 2, 2014, Pages 256-265

  Hénaut, Lucie ^a   Boudot, Cédric ^a   Massy, Ziad A ^a,b   Lopez Fernandez, Irene ^a,c   Dupont, Sebastien ^a   Mary, Aurélien ^a   Drüeke, Tilman B ^a   Kamel, Saïd ^a   Brazier, Michel ^a   Mentaverri, Romuald ^a,c  

^a UNIVERSITÉ DE PICARDIE JULES VERNE   (France)

^b LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

^c Multifaceted CaSR Initial Training Network   (France)

Author keywords

Calcimimetics; Calcium sensing receptor (CaSR); Human vascular smooth muscle cells (h VSMCs); Vascular calcification

Indexed keywords

AMG 641; CALCIMIMETIC AGENT; CALCIUM; CALCIUM SENSING RECEPTOR; SMALL INTERFERING RNA; TECALCET; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; DRUG MECHANISM; ENDOPLASMIC RETICULUM; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MINERALIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; VASCULAR SMOOTH MUSCLE CELL;

CALCIMIMETICS; CALCIUM-SENSING RECEPTOR (CASR); HUMAN VASCULAR SMOOTH MUSCLE CELLS (H-VSMCS); VASCULAR CALCIFICATION;

ANILINE COMPOUNDS; BIPHENYL COMPOUNDS; CALCIMIMETIC AGENTS; CALCIUM; CELL MEMBRANE; CELLS, CULTURED; COLLAGEN TYPE I; ENDOPLASMIC RETICULUM; HUMANS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PHENETHYLAMINES; PHENOTYPE; PROTEIN TRANSPORT; RECEPTORS, CALCIUM-SENSING; RNA INTERFERENCE; TIME FACTORS; TRANSFECTION; UP-REGULATION; VASCULAR CALCIFICATION;

EID: 84893032723     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvt249     Document Type: Article

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