Transient misfolding dominates multidomain protein folding

Nature Communications

Volumn 6, Issue , 2015, Pages

  Borgia, Alessandro ^a   Kemplen, Katherine R ^b   Borgia, Madeleine B ^a   Soranno, Andrea ^a   Shammas, Sarah ^b   Wunderlich, Bengt ^a   Nettels, Daniel ^a   Best, Robert B ^c   Clarke, Jane ^b   Schuler, Benjamin ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; CONNECTIN; IMMUNOGLOBULIN; POLYPEPTIDE; AMYLOID;

CONCENTRATION (COMPOSITION); DIVERGENCE; EVOLUTIONARY THEORY; GENE EXPRESSION; PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENTROPY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HYDROGEN BOND; KINETICS; LANDSCAPE; MICROFLUIDICS; MOLECULAR DYNAMICS; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN MISFOLDING; PROTEIN REFOLDING; PROTEIN STABILITY; PROTEIN STRUCTURE; SEQUENCE ANALYSIS; SIMULATION; TANDEM REPEAT; CHEMISTRY; HUMAN; METABOLISM; PROTEIN TERTIARY STRUCTURE; PROTEIN UNFOLDING;

AMYLOID; CONNECTIN; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; KINETICS; MICROFLUIDICS; MOLECULAR DYNAMICS SIMULATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN UNFOLDING; REPETITIVE SEQUENCES, AMINO ACID;

EID: 84947229753     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms9861     Document Type: Article

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