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Volumn 1862, Issue 1, 2016, Pages 113-120

Leptin dose-dependently decreases atherosclerosis by attenuation of hypercholesterolemia and induction of adiponectin

Author keywords

Adipokine; Adiponectin; Atherosclerosis; Insulin resistance; Leptin; Obesity

Indexed keywords

ADIPONECTIN; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; INTERMEDIATE DENSITY LIPOPROTEIN; LEPTIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; RECOMBINANT LEPTIN; SODIUM CHLORIDE; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

EID: 84947227837     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2015.10.022     Document Type: Article
Times cited : (35)

References (39)
  • 1
    • 0032474427 scopus 로고    scopus 로고
    • American Heart Association call to action: obesity as a major risk factor for coronary heart disease
    • Eckel R.H., Krauss R.M., for the AHA Nutrition Committee American Heart Association call to action: obesity as a major risk factor for coronary heart disease. Circulation 1998, 97:2099-2100.
    • (1998) Circulation , vol.97 , pp. 2099-2100
    • Eckel, R.H.1    Krauss, R.M.2
  • 4
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • Friedman J.M., Halaas J.L. Leptin and the regulation of body weight in mammals. Nature 1998, 395:763-770.
    • (1998) Nature , vol.395 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 7
    • 0018139377 scopus 로고
    • Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice
    • Coleman D.L. Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia 1978, 14:141-148.
    • (1978) Diabetologia , vol.14 , pp. 141-148
    • Coleman, D.L.1
  • 12
    • 84869505095 scopus 로고    scopus 로고
    • Leptin treatment inhibits the progression of atherosclerosis by attenuating hypercholesterolemia in type 1 diabetic Ins2+/Akita:apoE-/- mice
    • Jun J.Y., Ma Z., Pyla R., Segar L. Leptin treatment inhibits the progression of atherosclerosis by attenuating hypercholesterolemia in type 1 diabetic Ins2+/Akita:apoE-/- mice. Atherosclerosis 2012, 225:341-347.
    • (2012) Atherosclerosis , vol.225 , pp. 341-347
    • Jun, J.Y.1    Ma, Z.2    Pyla, R.3    Segar, L.4
  • 14
    • 0037380627 scopus 로고    scopus 로고
    • Increased low-density lipoprotein oxidation and impaired high-density lipoprotein antioxidant defense are associated with increased macrophage homing and atherosclerosis in dyslipidemic obese mice: LCAT gene transfer decreases atherosclerosis
    • Mertens A., Verhamme P., Bielicki J.K., Phillips M.C., Quarck R., Verreth W., Stengel D., Ninio E., Navab M., Mackness B., Mackness M., Holvoet P. Increased low-density lipoprotein oxidation and impaired high-density lipoprotein antioxidant defense are associated with increased macrophage homing and atherosclerosis in dyslipidemic obese mice: LCAT gene transfer decreases atherosclerosis. Circulation 2003, 107:1640-1646.
    • (2003) Circulation , vol.107 , pp. 1640-1646
    • Mertens, A.1    Verhamme, P.2    Bielicki, J.K.3    Phillips, M.C.4    Quarck, R.5    Verreth, W.6    Stengel, D.7    Ninio, E.8    Navab, M.9    Mackness, B.10    Mackness, M.11    Holvoet, P.12
  • 19
    • 11144242800 scopus 로고    scopus 로고
    • Major reduction of atherosclerosis in fractalkine (CX3CL1)-deficient mice is at the brachiocephalic artery, not the aortic root
    • Teupser D., Pavlides S., Tan M., Gutierrez-Ramos J.-C., Kolbeck R., Breslow J.L. Major reduction of atherosclerosis in fractalkine (CX3CL1)-deficient mice is at the brachiocephalic artery, not the aortic root. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:17795-17800.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 17795-17800
    • Teupser, D.1    Pavlides, S.2    Tan, M.3    Gutierrez-Ramos, J.-C.4    Kolbeck, R.5    Breslow, J.L.6
  • 20
    • 69949114028 scopus 로고    scopus 로고
    • Metabolic effects of diets differing in glycaemic index depend on age and endogenous glucose-dependent insulinotrophic polypeptide in mice
    • Isken F., Weickert M.O., Tschöp M.H., Nogueiras R., Möhlig M., Abdelrahman A., Klaus S., Thorens B., Pfeiffer A.F. Metabolic effects of diets differing in glycaemic index depend on age and endogenous glucose-dependent insulinotrophic polypeptide in mice. Diabetologia 2009, 52:2159-2168.
    • (2009) Diabetologia , vol.52 , pp. 2159-2168
    • Isken, F.1    Weickert, M.O.2    Tschöp, M.H.3    Nogueiras, R.4    Möhlig, M.5    Abdelrahman, A.6    Klaus, S.7    Thorens, B.8    Pfeiffer, A.F.9
  • 22
    • 79953746844 scopus 로고    scopus 로고
    • Cosegregation of aortic root atherosclerosis and intermediate lipid phenotypes on chromosomes 2 and 8 in an intercross of C57BL/6 and BALBc/ByJ low-density lipoprotein receptor-/- mice
    • Burkhardt R., Sündermann S., Ludwig D., Ceglarek U., Holdt L.M., Thiery J., Teupser D. Cosegregation of aortic root atherosclerosis and intermediate lipid phenotypes on chromosomes 2 and 8 in an intercross of C57BL/6 and BALBc/ByJ low-density lipoprotein receptor-/- mice. Arterioscler. Thromb. Vasc. Biol. 2011, 31:775-784.
    • (2011) Arterioscler. Thromb. Vasc. Biol. , vol.31 , pp. 775-784
    • Burkhardt, R.1    Sündermann, S.2    Ludwig, D.3    Ceglarek, U.4    Holdt, L.M.5    Thiery, J.6    Teupser, D.7
  • 24
    • 0035966010 scopus 로고    scopus 로고
    • Transcriptional profiling reveals global defects in energy metabolism, lipoprotein, and bile acid synthesis and transport with reversal by leptin treatment in Ob/ob mouse liver
    • Liang C.-P., Tall A.R. Transcriptional profiling reveals global defects in energy metabolism, lipoprotein, and bile acid synthesis and transport with reversal by leptin treatment in Ob/ob mouse liver. J. Biol. Chem. 2001, 276:49066-49076.
    • (2001) J. Biol. Chem. , vol.276 , pp. 49066-49076
    • Liang, C.-P.1    Tall, A.R.2
  • 25
    • 0033517284 scopus 로고    scopus 로고
    • Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy
    • Shimomura I., Hammer R.E., Ikemoto S., Brown M.S., Goldstein J.L. Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy. Nature 1999, 401:73-76.
    • (1999) Nature , vol.401 , pp. 73-76
    • Shimomura, I.1    Hammer, R.E.2    Ikemoto, S.3    Brown, M.S.4    Goldstein, J.L.5
  • 27
    • 33644808371 scopus 로고    scopus 로고
    • Letter to the editor: associations between liver histology and carotid intima-media thickness in patients with nonalcoholic fatty liver disease
    • Targher G., Bertolini L., Padovani R., Zoppini G., Zenari L., Falezza G. Letter to the editor: associations between liver histology and carotid intima-media thickness in patients with nonalcoholic fatty liver disease. Arterioscler. Thromb. Vasc. Biol. 2005, 25:2687-2688.
    • (2005) Arterioscler. Thromb. Vasc. Biol. , vol.25 , pp. 2687-2688
    • Targher, G.1    Bertolini, L.2    Padovani, R.3    Zoppini, G.4    Zenari, L.5    Falezza, G.6
  • 28
    • 77956189968 scopus 로고    scopus 로고
    • The inflamed liver and atherosclerosis: a link between histologic severity of nonalcoholic fatty liver disease and increased cardiovascular risk
    • Alkhouri N., Tamimi T.-R., Yerian L., Lopez R., Zein N., Feldstein A. The inflamed liver and atherosclerosis: a link between histologic severity of nonalcoholic fatty liver disease and increased cardiovascular risk. Dig. Dis. Sci. 2010, 55:2644-2650.
    • (2010) Dig. Dis. Sci. , vol.55 , pp. 2644-2650
    • Alkhouri, N.1    Tamimi, T.-R.2    Yerian, L.3    Lopez, R.4    Zein, N.5    Feldstein, A.6
  • 29
    • 0037907471 scopus 로고    scopus 로고
    • Pivotal role of nitric oxide in the control of blood pressure after leptin administration
    • Frühbeck G. Pivotal role of nitric oxide in the control of blood pressure after leptin administration. Diabetes 1999, 48:903-908.
    • (1999) Diabetes , vol.48 , pp. 903-908
    • Frühbeck, G.1
  • 30
    • 0035128497 scopus 로고    scopus 로고
    • Leptin-induced lipolysis opposes the tonic inhibition of endogenous adenosine in white adipocytes
    • Frühbeck G., Gómez-Ambrosi J., Salvador J. Leptin-induced lipolysis opposes the tonic inhibition of endogenous adenosine in white adipocytes. FASEB J. 2001, 15:333-340.
    • (2001) FASEB J. , vol.15 , pp. 333-340
    • Frühbeck, G.1    Gómez-Ambrosi, J.2    Salvador, J.3
  • 31
    • 81855177709 scopus 로고    scopus 로고
    • Adiponectin and cardiovascular health: an update
    • Hui X., Lam K.S., Vanhoutte P.M., Xu A. Adiponectin and cardiovascular health: an update. Br. J. Pharmacol. 2012, 165:574-590.
    • (2012) Br. J. Pharmacol. , vol.165 , pp. 574-590
    • Hui, X.1    Lam, K.S.2    Vanhoutte, P.M.3    Xu, A.4
  • 34
    • 33748970803 scopus 로고    scopus 로고
    • Leptin and atherosclerosis
    • Beltowski J. Leptin and atherosclerosis. Atherosclerosis 2006, 189:47-60.
    • (2006) Atherosclerosis , vol.189 , pp. 47-60
    • Beltowski, J.1
  • 35
    • 0036000280 scopus 로고    scopus 로고
    • Leptin signalling
    • Sweeney G. Leptin signalling. Cell. Signal. 2002, 14:655-663.
    • (2002) Cell. Signal. , vol.14 , pp. 655-663
    • Sweeney, G.1
  • 36
    • 0035973147 scopus 로고    scopus 로고
    • Potential role of leptin in angiogenesis: leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro
    • Park H.Y., Kwon H.M., Lim H.J., Hong B.K., Lee J.Y., Park B.E., Jang Y., Cho S.Y., Kim H.S. Potential role of leptin in angiogenesis: leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro. Exp. Mol. Med. 2001, 33:95-102.
    • (2001) Exp. Mol. Med. , vol.33 , pp. 95-102
    • Park, H.Y.1    Kwon, H.M.2    Lim, H.J.3    Hong, B.K.4    Lee, J.Y.5    Park, B.E.6    Jang, Y.7    Cho, S.Y.8    Kim, H.S.9
  • 37
    • 0035844031 scopus 로고    scopus 로고
    • Leptin enhances the calcification of vascular cells: artery wall as a target of leptin
    • Parhami F., Tintut Y., Ballard A., Fogelman A.M., Demer L.L. Leptin enhances the calcification of vascular cells: artery wall as a target of leptin. Circ. Res. 2001, 88:954-960.
    • (2001) Circ. Res. , vol.88 , pp. 954-960
    • Parhami, F.1    Tintut, Y.2    Ballard, A.3    Fogelman, A.M.4    Demer, L.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.