메뉴 건너뛰기




Volumn 36, Issue 9, 2015, Pages 7107-7119

Demethoxycurcumin was prior to temozolomide on inhibiting proliferation and induced apoptosis of glioblastoma stem cells

Author keywords

Apoptosis; Demethoxycurcumin; Glioblastoma stem cell; Proliferation; Temozolomide

Indexed keywords

CASPASE 3; DEMETHOXYCURCUMIN; GLIAL FIBRILLARY ACIDIC PROTEIN; JANUS KINASE; LIPOCORTIN 5; MONOCLONAL ANTIBODY; PROTEIN BCL 2; PROTEIN BCL XL; REACTIVE OXYGEN METABOLITE; STAT3 PROTEIN; TEMOZOLOMIDE; CURCUMIN; DACARBAZINE;

EID: 84947129144     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-015-3427-x     Document Type: Article
Times cited : (26)

References (39)
  • 1
    • 77954331628 scopus 로고    scopus 로고
    • High-grade malignant glioma: ESMO clinical practice guidelines for diagnosis, treatment and follow-up
    • PID: 20555079
    • Stupp R, Tonn JC, Brada M, Pentheroudakis G, ESMO Guidelines Working Group. High-grade malignant glioma: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2010;21 Suppl 5:v190–3.
    • (2010) Ann Oncol , vol.21 , pp. 190-193
    • Stupp, R.1    Tonn, J.C.2    Brada, M.3    Pentheroudakis, G.4    ESMO Guidelines Working Group5
  • 2
    • 60849125726 scopus 로고    scopus 로고
    • Effective sensitization of temozolomide by ABT-888 is lost with development of temozolomide resistance in glioblastoma xenograft lines
    • COI: 1:CAS:528:DC%2BD1MXhvFamsbw%3D, PID: 19174557
    • Clarke MJ, Mulligan EA, Grogan PT, Mladek AC, Carlson BL, Schroeder MA, et al. Effective sensitization of temozolomide by ABT-888 is lost with development of temozolomide resistance in glioblastoma xenograft lines. Mol Cancer Ther. 2009;8(2):407–14.
    • (2009) Mol Cancer Ther , vol.8 , Issue.2 , pp. 407-414
    • Clarke, M.J.1    Mulligan, E.A.2    Grogan, P.T.3    Mladek, A.C.4    Carlson, B.L.5    Schroeder, M.A.6
  • 3
    • 20244372425 scopus 로고    scopus 로고
    • Randomized phase II study of temozolomide and radiotherapy compared with radiotherapy alone in newly diagnosed glioblastoma multiforme
    • COI: 1:CAS:528:DC%2BD2MXjsVyhsrg%3D, PID: 15800329
    • Athanassiou H, Synodinou M, Maragoudakis E, Paraskevaidis M, Verigos C, Misailidou D, et al. Randomized phase II study of temozolomide and radiotherapy compared with radiotherapy alone in newly diagnosed glioblastoma multiforme. J Clin Oncol. 2005;23(10):2372–7.
    • (2005) J Clin Oncol , vol.23 , Issue.10 , pp. 2372-2377
    • Athanassiou, H.1    Synodinou, M.2    Maragoudakis, E.3    Paraskevaidis, M.4    Verigos, C.5    Misailidou, D.6
  • 4
    • 33745726808 scopus 로고    scopus 로고
    • Brain tumour stem cells
    • COI: 1:CAS:528:DC%2BD28XkvVylt78%3D, PID: 16723989
    • Vescovi AL, Galli R, Reynolds BA. Brain tumour stem cells. Nat Rev Cancer. 2006;6(6):425–36.
    • (2006) Nat Rev Cancer , vol.6 , Issue.6 , pp. 425-436
    • Vescovi, A.L.1    Galli, R.2    Reynolds, B.A.3
  • 5
    • 9244243708 scopus 로고    scopus 로고
    • Molecular hydrogen beyond the optical edge of an isolated spiral galaxy
    • COI: 1:CAS:528:DC%2BD2cXpvVCjt7s%3D, PID: 15549098
    • Braine J, Herpin F. Molecular hydrogen beyond the optical edge of an isolated spiral galaxy. Nature. 2004;432(7015):369–71.
    • (2004) Nature , vol.432 , Issue.7015 , pp. 369-371
    • Braine, J.1    Herpin, F.2
  • 6
    • 84905053315 scopus 로고    scopus 로고
    • miR-125b inhibitor enhance the chemosensitivity of glioblastoma stem cells to temozolomide by targeting Bak1
    • COI: 1:CAS:528:DC%2BC2cXht1egurnN, PID: 24643683
    • Chen J, Fu X, Wan Y, Wang Z, Jiang D, Shi L. miR-125b inhibitor enhance the chemosensitivity of glioblastoma stem cells to temozolomide by targeting Bak1. Tumour Biol. 2014;35(7):6293–302.
    • (2014) Tumour Biol , vol.35 , Issue.7 , pp. 6293-6302
    • Chen, J.1    Fu, X.2    Wan, Y.3    Wang, Z.4    Jiang, D.5    Shi, L.6
  • 7
    • 0029648973 scopus 로고
    • Anti-tumourand antioxidant activity of natural curcuminoids
    • COI: 1:CAS:528:DyaK2MXntFCksbs%3D, PID: 7621448
    • Ruby AJ, Kuttan G, Babu KD, Rajasekharan KN, Kuttan R. Anti-tumourand antioxidant activity of natural curcuminoids. Cancer Lett. 1995;94(1):79–83.
    • (1995) Cancer Lett , vol.94 , Issue.1 , pp. 79-83
    • Ruby, A.J.1    Kuttan, G.2    Babu, K.D.3    Rajasekharan, K.N.4    Kuttan, R.5
  • 8
    • 65649116571 scopus 로고    scopus 로고
    • Demethoxycurcumin induces Bcl-2 mediated G2/M arrest and apoptosis in human glioma U87 cells
    • COI: 1:CAS:528:DC%2BD1MXmsVCgsbw%3D, PID: 19422808
    • Luthra PM, Kumar R, Prakash A. Demethoxycurcumin induces Bcl-2 mediated G2/M arrest and apoptosis in human glioma U87 cells. Biochem Biophys Res Commun. 2009;384(4):420–5.
    • (2009) Biochem Biophys Res Commun , vol.384 , Issue.4 , pp. 420-425
    • Luthra, P.M.1    Kumar, R.2    Prakash, A.3
  • 9
    • 0002857380 scopus 로고
    • The in vitro biology of human brain tumors
    • Thomas DGT, (ed), Johns Hopkins University Press, Baltimore
    • Darling JL. The in vitro biology of human brain tumors. In: Thomas DGT, editor. Neuro-oncology: primary malignant brain tumors. Baltimore: Johns Hopkins University Press; 1990. p. 1–25.
    • (1990) Neuro-oncology: primary malignant brain tumors , pp. 1-25
    • Darling, J.L.1
  • 10
    • 73649147994 scopus 로고    scopus 로고
    • MiR-125b is critical for the suppression of human U251 glioma stem cell proliferation
    • COI: 1:CAS:528:DC%2BC3cXjvVCqsQ%3D%3D, PID: 19948152
    • Shi L, Zhang J, Pan T, Zhou J, Gong W, Liu N, et al. MiR-125b is critical for the suppression of human U251 glioma stem cell proliferation. Brain Res. 2010;1312:120–6.
    • (2010) Brain Res , vol.1312 , pp. 120-126
    • Shi, L.1    Zhang, J.2    Pan, T.3    Zhou, J.4    Gong, W.5    Liu, N.6
  • 11
    • 84864687809 scopus 로고    scopus 로고
    • Gossypin induces G2/M arrest in human malignant glioma U251 cells by the activation of Chk1/Cdc25C pathway
    • COI: 1:CAS:528:DC%2BC38Xisl2qtb0%3D, PID: 21984341
    • Shi L, Chen J, Wang YY, Sun G, Liu JN, Zhang JX, et al. Gossypin induces G2/M arrest in human malignant glioma U251 cells by the activation of Chk1/Cdc25C pathway. Cell Mol Neurobiol. 2012;32(2):289–96.
    • (2012) Cell Mol Neurobiol , vol.32 , Issue.2 , pp. 289-296
    • Shi, L.1    Chen, J.2    Wang, Y.Y.3    Sun, G.4    Liu, J.N.5    Zhang, J.X.6
  • 12
    • 84863869068 scopus 로고    scopus 로고
    • MicroRNA-21 inhibitor sensitizes human glioblastoma U251 stem cells to chemotherapeutic drug temozolomide
    • COI: 1:CAS:528:DC%2BC38Xns1Shtr0%3D, PID: 22528454
    • Zhang S, Wan Y, Pan T, Gu X, Qian C, Sun G, et al. MicroRNA-21 inhibitor sensitizes human glioblastoma U251 stem cells to chemotherapeutic drug temozolomide. J Mol Neurosci. 2012;47(2):346–56.
    • (2012) J Mol Neurosci , vol.47 , Issue.2 , pp. 346-356
    • Zhang, S.1    Wan, Y.2    Pan, T.3    Gu, X.4    Qian, C.5    Sun, G.6
  • 13
    • 84863264780 scopus 로고    scopus 로고
    • Demethoxycurcumin retards cell growth and induces apoptosis in human brain malignant glioma GBM 8401 cells
    • PID: 22454662
    • Huang TY, Hsu CW, Chang WC, Wang MY, Wu JF, Hsu YC. Demethoxycurcumin retards cell growth and induces apoptosis in human brain malignant glioma GBM 8401 cells. Evid Based Complement Alternat Med. 2012;2012:396573.
    • (2012) Evid Based Complement Alternat Med , vol.2012 , pp. 396573
    • Huang, T.Y.1    Hsu, C.W.2    Chang, W.C.3    Wang, M.Y.4    Wu, J.F.5    Hsu, Y.C.6
  • 14
    • 79954484430 scopus 로고    scopus 로고
    • Neural stem/progenitors and glioma stem-like cells have differential sensitivity to chemotherapy
    • COI: 1:CAS:528:DC%2BC3MXjvVKgu70%3D, PID: 21346220
    • Gong X, Schwartz PH, Linskey ME, Bota DA. Neural stem/progenitors and glioma stem-like cells have differential sensitivity to chemotherapy. Neurology. 2011;76(13):1126–34.
    • (2011) Neurology , vol.76 , Issue.13 , pp. 1126-1134
    • Gong, X.1    Schwartz, P.H.2    Linskey, M.E.3    Bota, D.A.4
  • 15
    • 0035203755 scopus 로고    scopus 로고
    • Annexin V staining during reperfusion detects cardiomyocytes with unique properties
    • COI: 1:CAS:528:DC%2BD3MXosFylsL8%3D, PID: 11668053
    • Narayan P, Mentzer Jr RM, Lasley RD. Annexin V staining during reperfusion detects cardiomyocytes with unique properties. Am J Physiol Heart Circ Physiol. 2001;281(5):H1931–7.
    • (2001) Am J Physiol Heart Circ Physiol , vol.281 , Issue.5 , pp. 1931-1937
    • Narayan, P.1    Mentzer, R.M.2    Lasley, R.D.3
  • 16
    • 34548058841 scopus 로고    scopus 로고
    • Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism
    • COI: 1:CAS:528:DC%2BD2sXpt1ehtb0%3D, PID: 17522064
    • Sandur SK, Pandey MK, Sung B, Ahn KS, Murakami A, Sethi G, et al. Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism. Carcinogenesis. 2007;28(8):1765–73.
    • (2007) Carcinogenesis , vol.28 , Issue.8 , pp. 1765-1773
    • Sandur, S.K.1    Pandey, M.K.2    Sung, B.3    Ahn, K.S.4    Murakami, A.5    Sethi, G.6
  • 17
    • 78650905938 scopus 로고    scopus 로고
    • Dimethoxycurcumin, a structural analogue of curcumin, induces apoptosis in human renal carcinoma caki cells through the production of reactive oxygen species, the release of cytochrome C, and the activation of caspase-3
    • PID: 21221209
    • Lee JW, Hong HM, Kwon DD, Pae HO, Jeong HJ. Dimethoxycurcumin, a structural analogue of curcumin, induces apoptosis in human renal carcinoma caki cells through the production of reactive oxygen species, the release of cytochrome C, and the activation of caspase-3. Korean J Urol. 2010;51(12):870–8.
    • (2010) Korean J Urol , vol.51 , Issue.12 , pp. 870-878
    • Lee, J.W.1    Hong, H.M.2    Kwon, D.D.3    Pae, H.O.4    Jeong, H.J.5
  • 18
    • 80052558504 scopus 로고    scopus 로고
    • Acquisition of chemoresistance in gliomas is associated with increased mitochondrial coupling and decreased ROS production
    • COI: 1:CAS:528:DC%2BC3MXht1Gju7jJ, PID: 21931801
    • Oliva CR, Moellering DR, Gillespie GY, Griguer CE. Acquisition of chemoresistance in gliomas is associated with increased mitochondrial coupling and decreased ROS production. PLoS ONE. 2011;6(9):e24665.
    • (2011) PLoS ONE , vol.6 , Issue.9
    • Oliva, C.R.1    Moellering, D.R.2    Gillespie, G.Y.3    Griguer, C.E.4
  • 19
    • 84858972296 scopus 로고    scopus 로고
    • Inhibitory effects of enalaprilat on rat cardiac fibroblast proliferation via ROS/P38MAPK/TGF-β1 signaling pathway
    • COI: 1:CAS:528:DC%2BC38XktFaktLY%3D, PID: 22395404
    • Yu M, Zheng Y, Sun HX, Yu DJ. Inhibitory effects of enalaprilat on rat cardiac fibroblast proliferation via ROS/P38MAPK/TGF-β1 signaling pathway. Molecules. 2012;17(3):2738–51.
    • (2012) Molecules , vol.17 , Issue.3 , pp. 2738-2751
    • Yu, M.1    Zheng, Y.2    Sun, H.X.3    Yu, D.J.4
  • 20
    • 73349094986 scopus 로고    scopus 로고
    • Curcumin and cancer cells: how many ways can curry kill tumor cells selectively?
    • COI: 1:CAS:528:DC%2BD1MXhsFGmur7I, PID: 19590964
    • Ravindran J, Prasad S, Aggarwal BB. Curcumin and cancer cells: how many ways can curry kill tumor cells selectively? AAPS J. 2009;11(3):495–510.
    • (2009) AAPS J , vol.11 , Issue.3 , pp. 495-510
    • Ravindran, J.1    Prasad, S.2    Aggarwal, B.B.3
  • 21
    • 0037474270 scopus 로고    scopus 로고
    • Opposite regulation of Myc and p21waf1 transcription by STAT3 proteins
    • PID: 12438313
    • Barré B, Avril S, Coqueret O. Opposite regulation of Myc and p21waf1 transcription by STAT3 proteins. J Biol Chem. 2003;278(5):2990–6.
    • (2003) J Biol Chem , vol.278 , Issue.5 , pp. 2990-2996
    • Barré, B.1    Avril, S.2    Coqueret, O.3
  • 22
    • 84869222346 scopus 로고    scopus 로고
    • Murine myeloid dendritic cells that phagocytose apoptotic T cells inhibit the immune response via NO
    • COI: 1:CAS:528:DC%2BC38XhvVSiu7vL, PID: 23166651
    • Zhong K, Song W, Wang Q, Wang C, Liu X, Chen D, et al. Murine myeloid dendritic cells that phagocytose apoptotic T cells inhibit the immune response via NO. PLoS ONE. 2012;7(11):e49378.
    • (2012) PLoS ONE , vol.7 , Issue.11
    • Zhong, K.1    Song, W.2    Wang, Q.3    Wang, C.4    Liu, X.5    Chen, D.6
  • 23
    • 24944554988 scopus 로고    scopus 로고
    • Inhibition of IL-10-induced STAT3 activation by 15-deoxy-delta12,14-prostaglandin J2
    • COI: 1:CAS:528:DC%2BD2MXmsV2is70%3D
    • Ji JD, Kim HJ, Rho YH, Choi SJ, Lee YH, Cheon HJ, et al. Inhibition of IL-10-induced STAT3 activation by 15-deoxy-delta12,14-prostaglandin J2. Rheumatology (Oxford). 2005;44(8):983–8.
    • (2005) Rheumatology (Oxford) , vol.44 , Issue.8 , pp. 983-988
    • Ji, J.D.1    Kim, H.J.2    Rho, Y.H.3    Choi, S.J.4    Lee, Y.H.5    Cheon, H.J.6
  • 24
    • 0031953999 scopus 로고    scopus 로고
    • Bcl-2 and Bcl-xL in peroxide-resistant A549 and U87MG cells
    • COI: 1:CAS:528:DyaK1cXislKmu7w%3D, PID: 9579023
    • Bojes HK, Suresh PK, Mills EM, Spitz DR, Sim JE, Kehrer JP. Bcl-2 and Bcl-xL in peroxide-resistant A549 and U87MG cells. Toxicol Sci. 1998;42(2):109–16.
    • (1998) Toxicol Sci , vol.42 , Issue.2 , pp. 109-116
    • Bojes, H.K.1    Suresh, P.K.2    Mills, E.M.3    Spitz, D.R.4    Sim, J.E.5    Kehrer, J.P.6
  • 25
    • 75149132946 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 1-mediated Bcl-xL/Bcl-2 phosphorylation acts as a functional link coupling mitotic arrest and apoptosis
    • COI: 1:CAS:528:DC%2BC3cXhslars78%3D, PID: 19917720
    • Terrano DT, Upreti M, Chambers TC. Cyclin-dependent kinase 1-mediated Bcl-xL/Bcl-2 phosphorylation acts as a functional link coupling mitotic arrest and apoptosis. Mol Cell Biol. 2010;30(3):640–56.
    • (2010) Mol Cell Biol , vol.30 , Issue.3 , pp. 640-656
    • Terrano, D.T.1    Upreti, M.2    Chambers, T.C.3
  • 26
    • 84879744896 scopus 로고    scopus 로고
    • Demethoxycurcumin inhibits energy metabolic and oncogenic signaling pathways through AMPK activation in triple-negative breast cancer cells
    • COI: 1:CAS:528:DC%2BC3sXptVCjtrY%3D, PID: 23777448
    • Shieh JM, Chen YC, Lin YC, Lin JN, Chen WC, Chen YY, et al. Demethoxycurcumin inhibits energy metabolic and oncogenic signaling pathways through AMPK activation in triple-negative breast cancer cells. J Agric Food Chem. 2013;61(26):6366–75.
    • (2013) J Agric Food Chem , vol.61 , Issue.26 , pp. 6366-6375
    • Shieh, J.M.1    Chen, Y.C.2    Lin, Y.C.3    Lin, J.N.4    Chen, W.C.5    Chen, Y.Y.6
  • 27
    • 84861555754 scopus 로고    scopus 로고
    • Demethoxycurcumin inhibits cell proliferation, migration and invasion in prostate cancer cells
    • COI: 1:CAS:528:DC%2BC38XpsFOlt7g%3D, PID: 22552297
    • Ni X, Zhang A, Zhao Z, Shen Y, Wang S. Demethoxycurcumin inhibits cell proliferation, migration and invasion in prostate cancer cells. Oncol Rep. 2012;28(1):85–90.
    • (2012) Oncol Rep , vol.28 , Issue.1 , pp. 85-90
    • Ni, X.1    Zhang, A.2    Zhao, Z.3    Shen, Y.4    Wang, S.5
  • 28
    • 38349042198 scopus 로고    scopus 로고
    • Curcuminoids-cellular uptake by human primary colon cancer cells as quantitated by a sensitive HPLC assay and its relation with the inhibition of proliferation and apoptosis
    • COI: 1:CAS:528:DC%2BD2sXpslCktrc%3D, PID: 17760412
    • Hsu YC, Weng HC, Lin S, Chien YW. Curcuminoids-cellular uptake by human primary colon cancer cells as quantitated by a sensitive HPLC assay and its relation with the inhibition of proliferation and apoptosis. J Agric Food Chem. 2007;55(20):8213–22.
    • (2007) J Agric Food Chem , vol.55 , Issue.20 , pp. 8213-8222
    • Hsu, Y.C.1    Weng, H.C.2    Lin, S.3    Chien, Y.W.4
  • 29
    • 33646411225 scopus 로고    scopus 로고
    • Luteolin promotes degradation in signal transducer and activator of transcription 3 in human hepatoma cells: an implication for the antitumor potential of flavonoids
    • COI: 1:CAS:528:DC%2BD28XjvF2kt7o%3D, PID: 16651438
    • Selvendiran K, Koga H, Ueno T, Yoshida T, Maeyama M, Torimura T, et al. Luteolin promotes degradation in signal transducer and activator of transcription 3 in human hepatoma cells: an implication for the antitumor potential of flavonoids. Cancer Res. 2006;66(9):4826–34.
    • (2006) Cancer Res , vol.66 , Issue.9 , pp. 4826-4834
    • Selvendiran, K.1    Koga, H.2    Ueno, T.3    Yoshida, T.4    Maeyama, M.5    Torimura, T.6
  • 30
    • 79952256467 scopus 로고    scopus 로고
    • Role of oxidative stress in stem, cancer, and cancer stem cells
    • Dayem AA, Choi HY, Kim JH, Cho SG. Role of oxidative stress in stem, cancer, and cancer stem cells. Cancers (Basel). 2010;2(2):859–84.
    • (2010) Cancers (Basel) , vol.2 , Issue.2 , pp. 859-884
    • Dayem, A.A.1    Choi, H.Y.2    Kim, J.H.3    Cho, S.G.4
  • 31
    • 84869220310 scopus 로고    scopus 로고
    • Mechanism of temozolomide-induced anti-tumor effects on glioblastoma cells in vitro is via ROS-dependent SIRT1 signaling pathway
    • COI: 1:CAS:528:DC%2BC3sXptVegtbg%3D, PID: 23291065
    • Jiang JY, Sun Y, Yuan Y. Mechanism of temozolomide-induced anti-tumor effects on glioblastoma cells in vitro is via ROS-dependent SIRT1 signaling pathway. Zhonghua Zhong Liu Za Zhi. 2012;34(10):734–8.
    • (2012) Zhonghua Zhong Liu Za Zhi , vol.34 , Issue.10 , pp. 734-738
    • Jiang, J.Y.1    Sun, Y.2    Yuan, Y.3
  • 33
    • 77956485040 scopus 로고    scopus 로고
    • The nontoxic natural compound curcumin exerts anti-proliferative, anti-migratory, and anti-invasive properties against malignant gliomas
    • PID: 20840775
    • Senft C, Polacin M, Priester M, Seifert V, Kögel D, Weissenberger J. The nontoxic natural compound curcumin exerts anti-proliferative, anti-migratory, and anti-invasive properties against malignant gliomas. BMC Cancer. 2010;10:491.
    • (2010) BMC Cancer , vol.10 , pp. 491
    • Senft, C.1    Polacin, M.2    Priester, M.3    Seifert, V.4    Kögel, D.5    Weissenberger, J.6
  • 34
    • 84895762605 scopus 로고    scopus 로고
    • miR-125b inhibitor may enhance the invasion-prevention activity of temozolomide in glioblastoma stem cells by targeting PIAS3
    • COI: 1:CAS:528:DC%2BC2cXhs1Wru7k%3D, PID: 23857508
    • Shi L, Wan Y, Sun G, Zhang S, Wang Z, Zeng Y. miR-125b inhibitor may enhance the invasion-prevention activity of temozolomide in glioblastoma stem cells by targeting PIAS3. BioDrugs. 2014;28(1):41–54.
    • (2014) BioDrugs , vol.28 , Issue.1 , pp. 41-54
    • Shi, L.1    Wan, Y.2    Sun, G.3    Zhang, S.4    Wang, Z.5    Zeng, Y.6
  • 35
    • 19444385692 scopus 로고    scopus 로고
    • Stat3 regulates genes common to both wound healing and cancer
    • COI: 1:CAS:528:DC%2BD2MXktVKnurs%3D, PID: 15735721
    • Dauer DJ, Ferraro B, Song L, Yu B, Mora L, Buettner R, et al. Stat3 regulates genes common to both wound healing and cancer. Oncogene. 2005;24(21):3397–408.
    • (2005) Oncogene , vol.24 , Issue.21 , pp. 3397-3408
    • Dauer, D.J.1    Ferraro, B.2    Song, L.3    Yu, B.4    Mora, L.5    Buettner, R.6
  • 36
    • 0037028249 scopus 로고    scopus 로고
    • Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells
    • COI: 1:CAS:528:DC%2BD38Xpt1WitLo%3D, PID: 12466961
    • Rahaman SO, Harbor PC, Chernova O, Barnett GH, Vogelbaum MA, Haque SJ. Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells. Oncogene. 2002;21(55):8404–13.
    • (2002) Oncogene , vol.21 , Issue.55 , pp. 8404-8413
    • Rahaman, S.O.1    Harbor, P.C.2    Chernova, O.3    Barnett, G.H.4    Vogelbaum, M.A.5    Haque, S.J.6
  • 37
    • 0036554816 scopus 로고    scopus 로고
    • Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention
    • COI: 1:CAS:528:DC%2BD38XjsF2lsb4%3D, PID: 11948098
    • Buettner R, Mora LB, Jove R. Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. Clin Cancer Res. 2002;8(4):945–54.
    • (2002) Clin Cancer Res , vol.8 , Issue.4 , pp. 945-954
    • Buettner, R.1    Mora, L.B.2    Jove, R.3
  • 38
    • 56849131763 scopus 로고    scopus 로고
    • c-Myc is required for maintenance of glioma cancer stem cells
    • PID: 19020659
    • Wang J, Wang H, Li Z, Wu Q, Lathia JD, McLendon RE, et al. c-Myc is required for maintenance of glioma cancer stem cells. PLoS ONE. 2008;3(11):e3769.
    • (2008) PLoS ONE , vol.3 , Issue.11
    • Wang, J.1    Wang, H.2    Li, Z.3    Wu, Q.4    Lathia, J.D.5    McLendon, R.E.6
  • 39
    • 79952180735 scopus 로고    scopus 로고
    • Bone morphogenetic protein 4 inhibits cell proliferation and induces apoptosis in glioma stem cells
    • COI: 1:CAS:528:DC%2BC3MXisFWqu7g%3D, PID: 21355779
    • Zhou Z, Sun L, Wang Y, Wu Z, Geng J, Miu W, et al. Bone morphogenetic protein 4 inhibits cell proliferation and induces apoptosis in glioma stem cells. Cancer Biother Radiopharm. 2011;26(1):77–83.
    • (2011) Cancer Biother Radiopharm , vol.26 , Issue.1 , pp. 77-83
    • Zhou, Z.1    Sun, L.2    Wang, Y.3    Wu, Z.4    Geng, J.5    Miu, W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.