메뉴 건너뛰기




Volumn 20, Issue 6, 2015, Pages 643-651

Eculizumab use in kidney transplantation

Author keywords

Antibody mediated rejection; Atypical hemolytic uremic syndrome; C3 glomerulopathy; Complement system; Delayed graft function; Eculizumab; Kidney transplantation

Indexed keywords

COMPLEMENT COMPONENT C5; ECULIZUMAB; IMMUNOSUPPRESSIVE AGENT; MONOCLONAL ANTIBODY;

EID: 84947127540     PISSN: 10872418     EISSN: 15317013     Source Type: Journal    
DOI: 10.1097/MOT.0000000000000249     Document Type: Review
Times cited : (23)

References (39)
  • 1
    • 82155197132 scopus 로고    scopus 로고
    • Functional modulation of human mono-cytes derived DCs by anaphylatoxins C3a and C5a
    • Li K, Fazekasova H, Wang N, et al. Functional modulation of human mono-cytes derived DCs by anaphylatoxins C3a and C5a. Immunobiology 2012; 217:65-73.
    • (2012) Immunobiology , vol.217 , pp. 65-73
    • Li, K.1    Fazekasova, H.2    Wang, N.3
  • 2
    • 84930053899 scopus 로고    scopus 로고
    • Molecules great and small: The complement system
    • Mathern DR, Heeger PS. Molecules great and small: the complement system. Clin J Am Soc Nephrol 2015; 10:1636-1650.
    • (2015) Clin J Am Soc Nephrol , vol.10 , pp. 1636-1650
    • Mathern, D.R.1    Heeger, P.S.2
  • 3
    • 77954048044 scopus 로고    scopus 로고
    • Thrombotic microangiopathy after kidney transplantation
    • Noris M, Remuzzi G. Thrombotic microangiopathy after kidney transplantation. Am J Transplant 2010; 10:1517-1523.
    • (2010) Am J Transplant , vol.10 , pp. 1517-1523
    • Noris, M.1    Remuzzi, G.2
  • 4
    • 84887024143 scopus 로고    scopus 로고
    • Managing and preventing atypical hemolytic uremic syndrome recurrence after kidney transplantation
    • Noris M, Remuzzi G. Managing and preventing atypical hemolytic uremic syndrome recurrence after kidney transplantation. Curr Opin Nephrol Hyper-tens 2013; 22:704-712.
    • (2013) Curr Opin Nephrol Hyper-tens , vol.22 , pp. 704-712
    • Noris, M.1    Remuzzi, G.2
  • 5
    • 84874417661 scopus 로고    scopus 로고
    • Complement genes strongly predict recurrence and graft outcome in adult renal transplant recipients with atypical hemolytic and uremic syndrome
    • Le Quintrec M, Zuber J, Moulin B, et al. Complement genes strongly predict recurrence and graft outcome in adult renal transplant recipients with atypical hemolytic and uremic syndrome. Am J Transplant 2013; 13:663-675.
    • (2013) Am J Transplant , vol.13 , pp. 663-675
    • Le Quintrec, M.1    Zuber, J.2    Moulin, B.3
  • 6
    • 84929128976 scopus 로고    scopus 로고
    • Efficacy and safety of eculizumab in atypical hemolytic uremic syndrome from 2-year extensions of phase 2 studies
    • Licht C, Greenbaum LA, Muus P, et al. Efficacy and safety of eculizumab in atypical hemolytic uremic syndrome from 2-year extensions of phase 2 studies. Kidney Int 2015; 87:1061-1073.
    • (2015) Kidney Int , vol.87 , pp. 1061-1073
    • Licht, C.1    Greenbaum, L.A.2    Muus, P.3
  • 7
    • 84870534251 scopus 로고    scopus 로고
    • Eculizumab for atypical hemolytic uremic syndrome recurrence in renal transplantation
    • Zuber J, Le Quintrec M, Krid S, et al. Eculizumab for atypical hemolytic uremic syndrome recurrence in renal transplantation. Am J Transplant 2012; 12:3337-3354.
    • (2012) Am J Transplant , vol.12 , pp. 3337-3354
    • Zuber, J.1    Le Quintrec, M.2    Krid, S.3
  • 8
    • 84947130868 scopus 로고    scopus 로고
    • A national specialized service in England for atypical haemolytic uraemic syndrome - The first year's experience
    • April. Epub ahead of print.
    • Sheerin NS, Kavanagh D, Goodship TH, Johnson S. A national specialized service in England for atypical haemolytic uraemic syndrome-the first year's experience. QJM 2015; April. Epub ahead of print.
    • (2015) QJM
    • Sheerin, N.S.1    Kavanagh, D.2    Goodship, T.H.3    Johnson, S.4
  • 9
    • 84917673672 scopus 로고    scopus 로고
    • Atypical hemolytic uremic syndrome recurrence after kidney transplantation
    • Matar D, Naqvi F, Racusen LC, et al. Atypical hemolytic uremic syndrome recurrence after kidney transplantation. Transplantation 2014; 98:1205-1212.
    • (2014) Transplantation , vol.98 , pp. 1205-1212
    • Matar, D.1    Naqvi, F.2    Racusen, L.C.3
  • 11
    • 34548491156 scopus 로고    scopus 로고
    • New approaches to the treatment of dense deposit disease
    • Smith RJ, Alexander J, Barlow PN, et al. New approaches to the treatment of dense deposit disease. J Am Soc Nephrol 2007; 18:2447-2456.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 2447-2456
    • Smith, R.J.1    Alexander, J.2    Barlow, P.N.3
  • 13
    • 84947130293 scopus 로고    scopus 로고
    • Atypical hemolytic uremic syndrome postkidney transplantation: Two case reports and review of the literature
    • Alasfar S, Alachkar N. Atypical hemolytic uremic syndrome postkidney transplantation: two case reports and review of the literature. Front Med (Lausanne) 2014; 1:52.
    • (2014) Front Med (Lausanne) , vol.1 , pp. 52
    • Alasfar, S.1    Alachkar, N.2
  • 14
    • 84867993256 scopus 로고    scopus 로고
    • Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies
    • Zuber J, Fakhouri F, Roumenina LT, et al. Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies. Nat Rev Nephrol 2012; 8:643-657.
    • (2012) Nat Rev Nephrol , vol.8 , pp. 643-657
    • Zuber, J.1    Fakhouri, F.2    Roumenina, L.T.3
  • 15
    • 84863512960 scopus 로고    scopus 로고
    • Pathology after eculizumab in dense deposit disease andC3 GN
    • Herlitz LC, Bomback AS, Markowitz GS, et al. Pathology after eculizumab in dense deposit disease andC3 GN. J Am Soc Nephrol 2012; 23:1229-1237.
    • (2012) J Am Soc Nephrol , vol.23 , pp. 1229-1237
    • Herlitz, L.C.1    Bomback, A.S.2    Markowitz, G.S.3
  • 16
    • 84883261341 scopus 로고    scopus 로고
    • Eculizumab and recurrent C3 glomerulone-phritis
    • Gurkan S, Fyfe B, Weiss L, et al. Eculizumab and recurrent C3 glomerulone-phritis. Pediatr Nephrol 2013; 28:1975-1981.
    • (2013) Pediatr Nephrol , vol.28 , pp. 1975-1981
    • Gurkan, S.1    Fyfe, B.2    Weiss, L.3
  • 17
    • 84555210096 scopus 로고    scopus 로고
    • Terminal complement inhibition decreases antibody-mediated rejection in sensitized renal transplant recipients
    • Stegall MD, Diwan T, Raghavaiah S, et al. Terminal complement inhibition decreases antibody-mediated rejection in sensitized renal transplant recipients. Am J Transplant 2011; 11:2405-2413.
    • (2011) Am J Transplant , vol.11 , pp. 2405-2413
    • Stegall, M.D.1    Diwan, T.2    Raghavaiah, S.3
  • 18
    • 84928089457 scopus 로고    scopus 로고
    • Positive crossmatch kidney transplant recipients treated with eculizumab: Outcomes beyond 1 year
    • Cornell LD, Schinstock CA, Gandhi MJ, Kremers WK, Stegall MD. Positive crossmatch kidney transplant recipients treated with eculizumab: outcomes beyond 1 year. Am J Transplant 2015; 15:1293-1302.
    • (2015) Am J Transplant , vol.15 , pp. 1293-1302
    • Cornell, L.D.1    Schinstock, C.A.2    Gandhi, M.J.3    Kremers, W.K.4    Stegall, M.D.5
  • 19
    • 84911129829 scopus 로고    scopus 로고
    • Antibody-mediated rejection despite inhibition of terminal complement
    • Bentall A, Tyan DB, Sequeira F, et al. Antibody-mediated rejection despite inhibition of terminal complement. Transpl Int 2014; 27:1235-1243.
    • (2014) Transpl Int , vol.27 , pp. 1235-1243
    • Bentall, A.1    Tyan, D.B.2    Sequeira, F.3
  • 20
    • 84927798214 scopus 로고    scopus 로고
    • Report of the inefficacy of eculizumab in two cases of severe antibody-mediated rejection of renal grafts
    • Burbach M, Suberbielle C, Brochériou I, et al. Report of the inefficacy of eculizumab in two cases of severe antibody-mediated rejection of renal grafts. Transplantation 2014; 98:1056-1059.
    • (2014) Transplantation , vol.98 , pp. 1056-1059
    • Burbach, M.1    Suberbielle, C.2    Brochériou, I.3
  • 21
    • 84922014185 scopus 로고    scopus 로고
    • Eculizumab and splenectomy as salvage therapy for severe antibody-mediated rejection after HLA-incompa-tible kidney transplantation
    • Orandi BJ, Zachary AA, Dagher NN, et al. Eculizumab and splenectomy as salvage therapy for severe antibody-mediated rejection after HLA-incompa-tible kidney transplantation. Transplantation 2014; 98:857-863.
    • (2014) Transplantation , vol.98 , pp. 857-863
    • Orandi, B.J.1    Zachary, A.A.2    Dagher, N.N.3
  • 22
    • 84869038452 scopus 로고    scopus 로고
    • Eculizumab treatment of acute antibody-mediated rejection in renal transplantation: Case reports
    • González-Roncero F, Suñer M, Bernal G, et al. Eculizumab treatment of acute antibody-mediated rejection in renal transplantation: case reports. Transplant Proc 2012; 44:2690-2694.
    • (2012) Transplant Proc , vol.44 , pp. 2690-2694
    • González-Roncero, F.1    Suñer, M.2    Bernal, G.3
  • 23
    • 84876868259 scopus 로고    scopus 로고
    • Eculizumab for salvage treatment of refractory antibody-mediated rejection in kidney transplant patients: Case reports
    • Kocak B, Arpali E, Demiralp E, et al. Eculizumab for salvage treatment of refractory antibody-mediated rejection in kidney transplant patients: case reports. Transplant Proc 2013; 45:1022-1025.
    • (2013) Transplant Proc , vol.45 , pp. 1022-1025
    • Kocak, B.1    Arpali, E.2    Demiralp, E.3
  • 24
    • 58049206825 scopus 로고    scopus 로고
    • The use of antibody to complement protein C5 for salvage treatment of severe antibody-mediated rejection
    • Locke JE, Magro CM, Singer AL, et al. The use of antibody to complement protein C5 for salvage treatment of severe antibody-mediated rejection. Am J Transplant 2009; 9:231-235.
    • (2009) Am J Transplant , vol.9 , pp. 231-235
    • Locke, J.E.1    Magro, C.M.2    Singer, A.L.3
  • 25
    • 77956133521 scopus 로고    scopus 로고
    • Eculizumab, bortezomib and kidney paired donation facilitate transplantation of a highly sensitized patient without vascular access
    • Lonze BE, Dagher NN, Simpkins CE, et al. Eculizumab, bortezomib and kidney paired donation facilitate transplantation of a highly sensitized patient without vascular access. Am J Transplant 2010; 10:2154-2160.
    • (2010) Am J Transplant , vol.10 , pp. 2154-2160
    • Lonze, B.E.1    Dagher, N.N.2    Simpkins, C.E.3
  • 26
    • 79960120521 scopus 로고    scopus 로고
    • Prompt reversal of a severe complement activation by eculizumab in a patient undergoing intentional ABO-incompatible pancreas and kidney transplantation
    • Biglarnia AR, Nilsson B, Nilsson T, et al. Prompt reversal of a severe complement activation by eculizumab in a patient undergoing intentional ABO-incompatible pancreas and kidney transplantation. Transpl Int 2011; 24:e61-e66.
    • (2011) Transpl Int , vol.24 , pp. e61-e66
    • Biglarnia, A.R.1    Nilsson, B.2    Nilsson, T.3
  • 27
    • 84870244762 scopus 로고    scopus 로고
    • Case report: Eculizumab rescue of severe accelerated antibody-mediated rejection after ABO-incompatible kidney transplant
    • Stewart ZA, Collins TE, Schlueter AJ, et al. Case report: eculizumab rescue of severe accelerated antibody-mediated rejection after ABO-incompatible kidney transplant. Transplant Proc 2012; 44:3033-3036.
    • (2012) Transplant Proc , vol.44 , pp. 3033-3036
    • Stewart, Z.A.1    Collins, T.E.2    Schlueter, A.J.3
  • 28
    • 84865611225 scopus 로고    scopus 로고
    • Antibody mediated rejection associated with complement factor h-related protein 3/1 deficiency successfully treated with eculizumab
    • Noone D, Al-Matrafi J, Tinckam K, et al. Antibody mediated rejection associated with complement factor h-related protein 3/1 deficiency successfully treated with eculizumab. Am J Transplant 2012; 12:2546-2553.
    • (2012) Am J Transplant , vol.12 , pp. 2546-2553
    • Noone, D.1    Al-Matrafi, J.2    Tinckam, K.3
  • 29
    • 84891825219 scopus 로고    scopus 로고
    • Plasmapheresis-resistantacutehumoralrejection successfully treated with anti-C5 antibody
    • Ghirardo G, Benetti E, Poli F, et al. Plasmapheresis-resistantacutehumoralrejection successfully treated with anti-C5 antibody. Pediatr Transplant 2014; 18:E1-E5.
    • (2014) Pediatr Transplant , vol.18 , pp. E1-E5
    • Ghirardo, G.1    Benetti, E.2    Poli, F.3
  • 30
    • 0026629923 scopus 로고
    • Renal involvement in primary antiphospholipid syndrome
    • Amigo MC, Garcia-Torres R, Robles M, et al. Renal involvement in primary antiphospholipid syndrome. J Rheumatol 1992; 19:1181-1185.
    • (1992) J Rheumatol , vol.19 , pp. 1181-1185
    • Amigo, M.C.1    Garcia-Torres, R.2    Robles, M.3
  • 31
    • 0346850621 scopus 로고    scopus 로고
    • Catastrophic antiphospholipid syndrome: Where do we stand?
    • Erkan D, Cervera R, Asherson RA. Catastrophic antiphospholipid syndrome: where do we stand? Arthritis Rheum 2003; 48:3320-3327.
    • (2003) Arthritis Rheum , vol.48 , pp. 3320-3327
    • Erkan, D.1    Cervera, R.2    Asherson, R.A.3
  • 32
    • 84895064562 scopus 로고    scopus 로고
    • Eculizumab prevents recurrent antiphospholipid antibody syndrome and enables successful renal transplantation
    • Lonze BE, Zachary AA, Magro CM, et al. Eculizumab prevents recurrent antiphospholipid antibody syndrome and enables successful renal transplantation. Am J Transplant 2014; 14:459-465.
    • (2014) Am J Transplant , vol.14 , pp. 459-465
    • Lonze, B.E.1    Zachary, A.A.2    Magro, C.M.3
  • 33
    • 84857190406 scopus 로고    scopus 로고
    • Eculizumab in acute recurrence of thrombotic microangiopathy after renal transplantation
    • Hadaya K, Ferrari-Lacraz S, Fumeaux D, et al. Eculizumab in acute recurrence of thrombotic microangiopathy after renal transplantation. Am J Transplant 2011; 11:2523-2527.
    • (2011) Am J Transplant , vol.11 , pp. 2523-2527
    • Hadaya, K.1    Ferrari-Lacraz, S.2    Fumeaux, D.3
  • 34
    • 84881372189 scopus 로고    scopus 로고
    • Eculizumab improves posttransplant thrombotic microangiopathy due to antiphospholipid syndrome recurrence but fails to prevent chronic vascular changes
    • Canaud G, Kamar N, Anglicheau D, et al. Eculizumab improves posttransplant thrombotic microangiopathy due to antiphospholipid syndrome recurrence but fails to prevent chronic vascular changes. Am J Transplant 2013; 13:2179-2185.
    • (2013) Am J Transplant , vol.13 , pp. 2179-2185
    • Canaud, G.1    Kamar, N.2    Anglicheau, D.3
  • 35
    • 84865978985 scopus 로고    scopus 로고
    • C3a and C5a promote renal ischemia-reperfusion injury
    • Peng Q, Li K, Smyth LA, et al. C3a and C5a promote renal ischemia-reperfusion injury. J Am Soc Nephrol 2012; 23:1474-1485.
    • (2012) J Am Soc Nephrol , vol.23 , pp. 1474-1485
    • Peng, Q.1    Li, K.2    Smyth, L.A.3
  • 36
    • 84895539873 scopus 로고    scopus 로고
    • Monoclonal antibody therapy and renal transplantation: Focus on adverse effects
    • Zaza G, Tomei P, Granata S, et al. Monoclonal antibody therapy and renal transplantation: focus on adverse effects. Toxins (Basel) 2014; 6:869-891.
    • (2014) Toxins (Basel) , vol.6 , pp. 869-891
    • Zaza, G.1    Tomei, P.2    Granata, S.3
  • 37
    • 84931053811 scopus 로고    scopus 로고
    • Use of serogroup B meningococcal vaccines in persons aged >10 years at increased risk for serogroup B meningococcal disease: Recommendations of the Advisory Committee on Immunization Practices
    • Folaranmi T, Rubin L, Martin SW, et al. Use of serogroup B meningococcal vaccines in persons aged >10 years at increased risk for serogroup B meningococcal disease: recommendations of the Advisory Committee on Immunization Practices. Morb Mortal Wkly Rep 2015; 64:608-612.
    • (2015) Morb Mortal Wkly Rep , vol.64 , pp. 608-612
    • Folaranmi, T.1    Rubin, L.2    Martin, S.W.3
  • 38
    • 84874435634 scopus 로고    scopus 로고
    • Meningococcal sepsis complicating eculizumab treatment despite prior vaccination
    • Struijk GH, Bouts AH, Rijkers GT, et al. Meningococcal sepsis complicating eculizumab treatment despite prior vaccination. Am J Transplant 2013; 13:819-820.
    • (2013) Am J Transplant , vol.13 , pp. 819-820
    • Struijk, G.H.1    Bouts, A.H.2    Rijkers, G.T.3
  • 39
    • 84909642930 scopus 로고    scopus 로고
    • Opportunity cost of funding drugs for rare diseases: The cost-effectiveness of eculizumab in paroxysmal nocturnal hemoglobinuria
    • Coyle D, Cheung MC, Evans GA. Opportunity cost of funding drugs for rare diseases: the cost-effectiveness of eculizumab in paroxysmal nocturnal hemoglobinuria. Med Decis Making 2014; 34:1016-1029.
    • (2014) Med Decis Making , vol.34 , pp. 1016-1029
    • Coyle, D.1    Cheung, M.C.2    Evans, G.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.