메뉴 건너뛰기




Volumn 21, Issue 6, 2015, Pages 576-585

Heparin-induced thrombocytopenia

Author keywords

Disseminated intravascular coagulation; Heparin induced thrombocytopenia; Ischemic limb gangrene with pulses; Shock liver

Indexed keywords

BLOOD CLOTTING FACTOR 7; D DIMER; HEPARIN; HEPARIN PLATELET FACTOR 4 ANTIBODY; ANTICOAGULANT AGENT; THROMBOCYTE FACTOR 4;

EID: 84947071610     PISSN: 10705295     EISSN: 15317072     Source Type: Journal    
DOI: 10.1097/MCC.0000000000000259     Document Type: Review
Times cited : (50)

References (89)
  • 1
    • 0030281338 scopus 로고    scopus 로고
    • A 14-year study of heparin-induced thrombocyto-penia
    • Warkentin TE, Kelton JG. A 14-year study of heparin-induced thrombocyto-penia. Am J Med 1996; 101:502-507.
    • (1996) Am J Med , vol.101 , pp. 502-507
    • Warkentin, T.E.1    Kelton, J.G.2
  • 2
    • 0029035681 scopus 로고
    • Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin
    • Warkentin TE, Levine MN, Hirsh J, et al. Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin. N Engl J Med 1995; 332:1330-1335.
    • (1995) N Engl J Med , vol.332 , pp. 1330-1335
    • Warkentin, T.E.1    Levine, M.N.2    Hirsh, J.3
  • 3
    • 0037610515 scopus 로고    scopus 로고
    • An improved definition of immune heparin-induced thrombocytopenia in postoperative orthopedic patients
    • Warkentin TE, Roberts RS, Hirsh J, Kelton JG. An improved definition of immune heparin-induced thrombocytopenia in postoperative orthopedic patients. Arch Intern Med 2003; 163:2518-2524.
    • (2003) Arch Intern Med , vol.163 , pp. 2518-2524
    • Warkentin, T.E.1    Roberts, R.S.2    Hirsh, J.3    Kelton, J.G.4
  • 4
    • 84859986070 scopus 로고    scopus 로고
    • HITlights: A career perspective on heparin-induced thrombo-cytopenia
    • Warkentin TE. HITlights: a career perspective on heparin-induced thrombo-cytopenia. Am J Hematol 2012; 87 (Suppl 1):S92-S99.
    • (2012) Am J Hematol , vol.87 , pp. S92-S99
    • Warkentin, T.E.1
  • 5
    • 77955119891 scopus 로고    scopus 로고
    • Agents for the treatment of heparin-induced thrombocytope-nia
    • Warkentin TE. Agents for the treatment of heparin-induced thrombocytope-nia. Hematol/Oncol Clin N Am 2010; 24:755-775.
    • (2010) Hematol/Oncol Clin N Am , vol.24 , pp. 755-775
    • Warkentin, T.E.1
  • 6
    • 84941729325 scopus 로고    scopus 로고
    • Ischemic limb gangrene with pulses
    • Warkentin TE. Ischemic limb gangrene with pulses. N Engl J Med 2015; 373:642-655.
    • (2015) N Engl J Med , vol.373 , pp. 642-655
    • Warkentin, T.E.1
  • 7
    • 0020404337 scopus 로고
    • Heparin-induced thrombocytopenia: Association of thrombotic complications with heparin-induced IgG antibody that induces thromboxane synthesis in platelet aggregation
    • Chong BH, Pitney WR, Castaldi PA. Heparin-induced thrombocytopenia: association of thrombotic complications with heparin-induced IgG antibody that induces thromboxane synthesis in platelet aggregation. Lancet 1982; 2:1246-1249.
    • (1982) Lancet , vol.2 , pp. 1246-1249
    • Chong, B.H.1    Pitney, W.R.2    Castaldi, P.A.3
  • 8
    • 0026638091 scopus 로고
    • Platelet factor 4 complexed to heparin is the target for antibodies generated in heparin induced thrombocytopenia
    • Amiral J, Bridey F, Dreyfus M, et al. Platelet factor 4 complexed to heparin is the target for antibodies generated in heparin induced thrombocytopenia. Thromb Haemost 1992; 68:95-96.
    • (1992) Thromb Haemost , vol.68 , pp. 95-96
    • Amiral, J.1    Bridey, F.2    Dreyfus, M.3
  • 9
    • 0028014541 scopus 로고
    • Heparin-associated thrombocyto-penia: Isolation of the antibody and characterization of a multimolecular PF4-heparin complex as the major antigen
    • Greinacher A, Pötzsch B, Amiral J, et al. Heparin-associated thrombocyto-penia: isolation of the antibody and characterization of a multimolecular PF4-heparin complex as the major antigen. Thromb Haemost 1994; 71:247-251.
    • (1994) Thromb Haemost , vol.71 , pp. 247-251
    • Greinacher, A.1    Pötzsch, B.2    Amiral, J.3
  • 10
    • 0035797925 scopus 로고    scopus 로고
    • Delayed-onset heparin-induced thrombocytopenia and thrombosis
    • Warkentin TE, Kelton JG. Delayed-onset heparin-induced thrombocytopenia and thrombosis. Ann Intern Med 2001; 135:502-506.
    • (2001) Ann Intern Med , vol.135 , pp. 502-506
    • Warkentin, T.E.1    Kelton, J.G.2
  • 11
    • 84907176614 scopus 로고    scopus 로고
    • Progressive thrombocytopenia after cardiac surgery in a 67-year-old man
    • Kopolovic I, Warkentin TE. Progressive thrombocytopenia after cardiac surgery in a 67-year-old man. CMAJ 2014; 186:929-933.
    • (2014) CMAJ , vol.186 , pp. 929-933
    • Kopolovic, I.1    Warkentin, T.E.2
  • 12
    • 84920555104 scopus 로고    scopus 로고
    • Heparin-independent, PF4-dependent binding of HIT antibodies to platelets: Implications for HIT patho-genesis
    • Padmanabhan A, Jones CG, Bougie DW, et al. Heparin-independent, PF4-dependent binding of HIT antibodies to platelets: implications for HIT patho-genesis. Blood 2015; 125:155-161.
    • (2015) Blood , vol.125 , pp. 155-161
    • Padmanabhan, A.1    Jones, C.G.2    Bougie, D.W.3
  • 13
    • 0027971564 scopus 로고
    • Sera from patients with heparin-induced thrombocytopenia generate platelet-derived microparticles with procoagulant activity: An explanation for the thrombotic complications of heparin-induced thrombocytopenia
    • Warkentin TE, Hayward CPM, Boshkov LK, et al. Sera from patients with heparin-induced thrombocytopenia generate platelet-derived microparticles with procoagulant activity: an explanation for the thrombotic complications of heparin-induced thrombocytopenia. Blood 1994; 84:3691-3699.
    • (1994) Blood , vol.84 , pp. 3691-3699
    • Warkentin, T.E.1    Cpm, H.2    Boshkov, L.K.3
  • 14
    • 78649742009 scopus 로고    scopus 로고
    • Monocyte-bound PF4 in the patho-genesis of heparin-induced thrombocytopenia
    • Rauova L, Hirsch JD, Greene TK, et al. Monocyte-bound PF4 in the patho-genesis of heparin-induced thrombocytopenia. Blood 2010; 116:5021-5031.
    • (2010) Blood , vol.116 , pp. 5021-5031
    • Rauova, L.1    Hirsch, J.D.2    Greene, T.K.3
  • 15
    • 34547122582 scopus 로고    scopus 로고
    • Clinical picture of heparin-induced thrombocytopenia
    • Warkentin TE, Greinacher A, editors Boca Raton, FL: CRC Press
    • Warkentin TE. Clinical picture of heparin-induced thrombocytopenia. In: Warkentin TE, Greinacher A, editors. Heparin-induced thrombocytopenia, 5th ed. Boca Raton, FL: CRC Press; 2013. pp. 24-76.
    • (2013) Heparin-induced Thrombocytopenia, 5th Ed , pp. 24-76
    • Warkentin, T.E.1
  • 16
    • 84937026507 scopus 로고    scopus 로고
    • Clinical practice heparin-induced thrombocytopenia
    • Greinacher A. Clinical practice heparin-induced thrombocytopenia. N Engl J Med 2015; 373:252-261.
    • (2015) N Engl J Med , vol.373 , pp. 252-261
    • Greinacher, A.1
  • 17
    • 0037905743 scopus 로고    scopus 로고
    • Central venous catheters and upper-extremity deep-vein thrombosis complicating immune heparin-induced thrombocytopenia
    • Hong AP, Cook DJ, Sigouin CS, Warkentin TE. Central venous catheters and upper-extremity deep-vein thrombosis complicating immune heparin-induced thrombocytopenia. Blood 2003; 101:3049-3051.
    • (2003) Blood , vol.101 , pp. 3049-3051
    • Hong, A.P.1    Cook, D.J.2    Sigouin, C.S.3    Warkentin, T.E.4
  • 18
    • 0037434883 scopus 로고    scopus 로고
    • Delayed-onset heparin-induced thrombocyto-penia and cerebral thrombosis after a single administration of unfractionated heparin
    • Warkentin TE, Bernstein RA. Delayed-onset heparin-induced thrombocyto-penia and cerebral thrombosis after a single administration of unfractionated heparin. N Engl J Med 2003; 348:1067-1069.
    • (2003) N Engl J Med , vol.348 , pp. 1067-1069
    • Warkentin, T.E.1    Bernstein, R.A.2
  • 19
    • 84921881363 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia presenting as bilateral adrenal hemorrhages
    • Warkentin TE, Safyan EL, Linkins LA. Heparin-induced thrombocytopenia presenting as bilateral adrenal hemorrhages. N Engl J Med 2015; 372:492-494.
    • (2015) N Engl J Med , vol.372 , pp. 492-494
    • Warkentin, T.E.1    Safyan, E.L.2    Linkins, L.A.3
  • 20
    • 53449094146 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: A historical perspective
    • Kelton JG, Warkentin TE. Heparin-induced thrombocytopenia: a historical perspective. Blood 2008; 112:2607-2616.
    • (2008) Blood , vol.112 , pp. 2607-2616
    • Kelton, J.G.1    Warkentin, T.E.2
  • 21
    • 45949103154 scopus 로고    scopus 로고
    • Treatment and prevention of heparin-induced thrombocytopenia. American College of Chest Physicians evidence-based clinical practice guidelines (8th edition)
    • Warkentin TE, Greinacher A, Koster A, Lincoff AM. Treatment and prevention of heparin-induced thrombocytopenia. American College of Chest Physicians evidence-based clinical practice guidelines (8th edition). Chest 2008; 133 (6 Suppl):340S-380S.
    • (2008) Chest , vol.133 , Issue.6 , pp. 340S-380S
    • Warkentin, T.E.1    Greinacher, A.2    Koster, A.3    Lincoff, A.M.4
  • 22
    • 0030702032 scopus 로고    scopus 로고
    • The pathogenesis of venous limb gangrene associated with heparin-induced thrombocytopenia
    • Warkentin TE, Elavathil LJ, Hayward CPM, et al. The pathogenesis of venous limb gangrene associated with heparin-induced thrombocytopenia. Ann Intern Med 1997; 127:804-812.
    • (1997) Ann Intern Med , vol.127 , pp. 804-812
    • Warkentin, T.E.1    Elavathil, L.J.2    Cpm, H.3
  • 23
    • 0347949656 scopus 로고    scopus 로고
    • Warfarin-induced skin necrosis and venous limb gangrene in the setting of heparin-induced thrombocytope-nia
    • Srinivasan AF, Rice L, Bartholomew JR, et al. Warfarin-induced skin necrosis and venous limb gangrene in the setting of heparin-induced thrombocytope-nia. Arch Intern Med 2004; 164:66-70.
    • (2004) Arch Intern Med , vol.164 , pp. 66-70
    • Srinivasan, A.F.1    Rice, L.2    Bartholomew, J.R.3
  • 24
    • 84882702920 scopus 로고    scopus 로고
    • Frequency of heparin-induced thrombocytopenia
    • Warkentin TE, Greinacher A, editors Boca Raton, FL: CRC Press
    • Linkins LA, Lee DH. Frequency of heparin-induced thrombocytopenia. In: Warkentin TE, Greinacher A, editors. Heparin-induced thrombocytopenia, 5th ed. Boca Raton, FL: CRC Press; 2013. pp. 110-150.
    • (2013) Heparin-induced Thrombocytopenia, 5th Ed , pp. 110-150
    • Linkins, L.A.1    Lee, D.H.2
  • 25
    • 33644971524 scopus 로고    scopus 로고
    • Evaluation of pretest clinical score (4 T's) for the diagnosis of heparin-induced thrombocytopenia in two clinical settings
    • Lo GK, Juhl D, Warkentin TE, et al. Evaluation of pretest clinical score (4 T's) for the diagnosis of heparin-induced thrombocytopenia in two clinical settings. J Thromb Haemost 2006; 4:759-765.
    • (2006) J Thromb Haemost , vol.4 , pp. 759-765
    • Lo, G.K.1    Juhl, D.2    Warkentin, T.E.3
  • 26
    • 77955037554 scopus 로고    scopus 로고
    • Nonnecrotizing heparin-induced skin lesions and the 4T's score
    • Warkentin TE, Linkins LA. Nonnecrotizing heparin-induced skin lesions and the 4T's score. J Thromb Haemost 2010; 8:1483-1485.
    • (2010) J Thromb Haemost , vol.8 , pp. 1483-1485
    • Warkentin, T.E.1    Linkins, L.A.2
  • 27
    • 84869834180 scopus 로고    scopus 로고
    • Predictive value of the 4Ts scoring system for heparin-induced thrombocytopenia: A systematic review and meta-analysis
    • Cuker A, Gimotty PA, Crowther MA, Warkentin TE. Predictive value of the 4Ts scoring system for heparin-induced thrombocytopenia: a systematic review and meta-analysis. Blood 2012; 120:4160-4167.
    • (2012) Blood , vol.120 , pp. 4160-4167
    • Cuker, A.1    Gimotty, P.A.2    Crowther, M.A.3    Warkentin, T.E.4
  • 28
    • 84902039374 scopus 로고    scopus 로고
    • Differential diagnosis of heparin-induced thrombo-cytopenia and scoring systems
    • Warkentin TE, Greinacher A, editors Boca Raton, FL: CRC Press
    • Warkentin TE, Cuker A. Differential diagnosis of heparin-induced thrombo-cytopenia and scoring systems. In: Warkentin TE, Greinacher A, editors. Heparin-induced thrombocytopenia, 5th ed. Boca Raton, FL: CRC Press; 2013. pp. 77-109.
    • (2013) Heparin-induced Thrombocytopenia, 5th Ed , pp. 77-109
    • Warkentin, T.E.1    Cuker, A.2
  • 29
    • 78650000811 scopus 로고    scopus 로고
    • The HIT Expert Probability (HEP) Score: A novel pretest probability model for heparin-induced thrombocyto-penia based on broad expert opinion
    • Cuker A, Arepally G, Crowther MA, et al. The HIT Expert Probability (HEP) Score: a novel pretest probability model for heparin-induced thrombocyto-penia based on broad expert opinion. J Thromb Haemost 2010; 8:2642-2650.
    • (2010) J Thromb Haemost , vol.8 , pp. 2642-2650
    • Cuker, A.1    Arepally, G.2    Crowther, M.A.3
  • 30
    • 0031974339 scopus 로고    scopus 로고
    • Greinacher A.Heparin-induced thrombocytopenia: Towards consensus
    • Warkentin TE, Chong BH, Greinacher A.Heparin-induced thrombocytopenia: towards consensus. Thromb Haemost 1998; 79:1-7.
    • (1998) Thromb Haemost , vol.79 , pp. 1-7
    • Warkentin, T.E.1    Chong, B.H.2
  • 31
    • 79960644200 scopus 로고    scopus 로고
    • HIT paradigms and paradoxes
    • Warkentin TE. HIT paradigms and paradoxes. J Thromb Haemost 2011; 9 (Suppl 1):105-117.
    • (2011) J Thromb Haemost , vol.9 , pp. 105-117
    • Warkentin, T.E.1
  • 32
    • 82755161996 scopus 로고    scopus 로고
    • Laboratory testing for heparin-induced thrombocytopenia: A conceptual framework and implications for diagnosis
    • Warkentin TE, Greinacher A, Gruel Y, et al. Laboratory testing for heparin-induced thrombocytopenia: a conceptual framework and implications for diagnosis. J Thromb Haemost 2011; 9:2498-2500.
    • (2011) J Thromb Haemost , vol.9 , pp. 2498-2500
    • Warkentin, T.E.1    Greinacher, A.2    Gruel, Y.3
  • 33
    • 0022640930 scopus 로고
    • A diagnostic test for heparin-induced thrombocytopenia
    • Sheridan D, Carter C, Kelton JG. A diagnostic test for heparin-induced thrombocytopenia. Blood 1986; 67:27-30.
    • (1986) Blood , vol.67 , pp. 27-30
    • Sheridan, D.1    Carter, C.2    Kelton, J.G.3
  • 34
    • 0026646478 scopus 로고
    • Determinants of donor platelet variability when testing for heparin-induced thrombocytopenia
    • Warkentin TE, Hayward CPM, Smith CA, et al. Determinants of donor platelet variability when testing for heparin-induced thrombocytopenia. J Lab Clin Med 1992; 120:371-379.
    • (1992) J Lab Clin Med , vol.120 , pp. 371-379
    • Warkentin, T.E.1    Cpm, H.2    Smith, C.A.3
  • 35
    • 0025951938 scopus 로고
    • A rapid and sensitive test for diagnosing heparin-associated thrombocytopenia
    • Greinacher A, Michels I, Kiefel V, Mueller-Eckhardt C. A rapid and sensitive test for diagnosing heparin-associated thrombocytopenia. Thromb Haemost 1991; 66:734-736.
    • (1991) Thromb Haemost , vol.66 , pp. 734-736
    • Greinacher, A.1    Michels, I.2    Kiefel, V.3    Mueller-Eckhardt, C.4
  • 38
    • 0038392539 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: Pathogenesis and management
    • Warkentin TE. Heparin-induced thrombocytopenia: pathogenesis and management. Br J Haematol 2003; 121:535-555.
    • (2003) Br J Haematol , vol.121 , pp. 535-555
    • Warkentin, T.E.1
  • 39
    • 84907164937 scopus 로고    scopus 로고
    • Acquired nonimmune thrombocytopenia
    • Marder VJ, Aird WC, Bennett JS, et al., editors Philadelphia: Lippincott Williams & Wilkins
    • Greinacher A, Warkentin TE. Acquired nonimmune thrombocytopenia. In: Marder VJ, Aird WC, Bennett JS, et al., editors. Hemostasis and thrombosis: basic principles and clinical practice, 6th ed. Philadelphia: Lippincott Williams & Wilkins; 2013. pp. 796-804.
    • (2013) Hemostasis and Thrombosis: Basic Principles and Clinical Practice, 6th Ed , pp. 796-804
    • Greinacher, A.1    Warkentin, T.E.2
  • 40
    • 0035953702 scopus 로고    scopus 로고
    • Temporal aspects of heparin-induced thrombocy-topenia
    • Warkentin TE, Kelton JG. Temporal aspects of heparin-induced thrombocy-topenia. N Engl J Med 2001; 344:1286-1292.
    • (2001) N Engl J Med , vol.344 , pp. 1286-1292
    • Warkentin, T.E.1    Kelton, J.G.2
  • 41
    • 65349122236 scopus 로고    scopus 로고
    • Studies of the immune response in heparin-induced thrombocytopenia
    • Warkentin TE, Sheppard JI, Moore JC, et al. Studies of the immune response in heparin-induced thrombocytopenia. Blood 2009; 113:4963-4969.
    • (2009) Blood , vol.113 , pp. 4963-4969
    • Warkentin, T.E.1    Sheppard, J.I.2    Moore, J.C.3
  • 42
    • 66949114594 scopus 로고    scopus 로고
    • Heparin-induced anaphylactic and anaphylac-toid reactions: Two distinct but overlapping syndromes
    • Warkentin TE, Greinacher A. Heparin-induced anaphylactic and anaphylac-toid reactions: two distinct but overlapping syndromes. Expert Opin Drug Saf 2009; 8:129-144.
    • (2009) Expert Opin Drug Saf , vol.8 , pp. 129-144
    • Warkentin, T.E.1    Greinacher, A.2
  • 43
    • 0028028417 scopus 로고
    • Transient global amnesia associated with acute heparin-induced thrombocytopenia
    • Warkentin TE, Hirte HW, Anderson DR, et al. Transient global amnesia associated with acute heparin-induced thrombocytopenia. Am J Med 1994; 97:489-491.
    • (1994) Am J Med , vol.97 , pp. 489-491
    • Warkentin, T.E.1    Hirte, H.W.2    Anderson, D.R.3
  • 44
    • 79959332217 scopus 로고    scopus 로고
    • Chills and limb pain following administration of low-molecular-weight heparin for treatment of acute venous thromboembolism
    • Hillis C, Warkentin TE, Taha K, Eikelboom JW. Chills and limb pain following administration of low-molecular-weight heparin for treatment of acute venous thromboembolism. Am J Hematol 2011; 86:603-606.
    • (2011) Am J Hematol , vol.86 , pp. 603-606
    • Hillis, C.1    Warkentin, T.E.2    Taha, K.3    Eikelboom, J.W.4
  • 45
    • 84899089518 scopus 로고    scopus 로고
    • Serological investigation of patients with a previous history of heparin-induced thrombocytopenia who are reexposed to heparin
    • Warkentin TE, Sheppard JI. Serological investigation of patients with a previous history of heparin-induced thrombocytopenia who are reexposed to heparin. Blood 2014; 123:2485-2493.
    • (2014) Blood , vol.123 , pp. 2485-2493
    • Warkentin, T.E.1    Sheppard, J.I.2
  • 46
    • 22144446420 scopus 로고    scopus 로고
    • Clinical features of heparin-induced thrombocytopenia including risk factors for thrombosis. A retrospective analysis of 408 patients
    • Greinacher A, Farner B, Kroll H, et al. Clinical features of heparin-induced thrombocytopenia including risk factors for thrombosis. A retrospective analysis of 408 patients. Thromb Haemost 2005; 94:132-135.
    • (2005) Thromb Haemost , vol.94 , pp. 132-135
    • Greinacher, A.1    Farner, B.2    Kroll, H.3
  • 48
    • 84855366474 scopus 로고    scopus 로고
    • Intraoperative anticoagulation and limb amputations in patients with immune heparin-induced thrombocytopenia who require vascular surgery
    • Warkentin TE, Pai M, Cook RJ. Intraoperative anticoagulation and limb amputations in patients with immune heparin-induced thrombocytopenia who require vascular surgery. J Thromb Haemost 2012; 10:148-150.
    • (2012) J Thromb Haemost , vol.10 , pp. 148-150
    • Warkentin, T.E.1    Pai, M.2    Cook, R.J.3
  • 49
    • 0030054018 scopus 로고    scopus 로고
    • Heparin-induced skin lesions
    • Warkentin TE. Heparin-induced skin lesions. Br J Haematol 1996; 92:494-497.
    • (1996) Br J Haematol , vol.92 , pp. 494-497
    • Warkentin, T.E.1
  • 50
    • 84937422038 scopus 로고    scopus 로고
    • Noninjection site necrotic skin lesions complicating postoperative heparin thromboprophylaxis
    • Tassava T, Warkentin TE. Noninjection site necrotic skin lesions complicating postoperative heparin thromboprophylaxis. Am J Hematol 2015; 90:747-750.
    • (2015) Am J Hematol , vol.90 , pp. 747-750
    • Tassava, T.1    Warkentin, T.E.2
  • 51
    • 79960629597 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: Real world issues
    • Linkins LA, Warkentin TE. Heparin-induced thrombocytopenia: real world issues. Semin Thromb Hemost 2011; 37:653-663.
    • (2011) Semin Thromb Hemost , vol.37 , pp. 653-663
    • Linkins, L.A.1    Warkentin, T.E.2
  • 52
    • 84937928371 scopus 로고    scopus 로고
    • Warfarin-induced venous limb ischemia/gangrene complicating cancer: A novel and clinically distinct syndrome
    • Warkentin TE, Cook RJ, Sarode R, et al. Warfarin-induced venous limb ischemia/gangrene complicating cancer: a novel and clinically distinct syndrome. Blood 2015; 126:486-493.
    • (2015) Blood , vol.126 , pp. 486-493
    • Warkentin, T.E.1    Cook, R.J.2    Sarode, R.3
  • 53
    • 82755187620 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia in critically ill patients
    • Warkentin TE. Heparin-induced thrombocytopenia in critically ill patients. Crit Care Clin 2011; 27:805-823.
    • (2011) Crit Care Clin , vol.27 , pp. 805-823
    • Warkentin, T.E.1
  • 54
    • 84865478911 scopus 로고    scopus 로고
    • Acute hepatic necrosis and ischemic limb necrosis
    • Siegal DM, Cook RJ, Warkentin TE. Acute hepatic necrosis and ischemic limb necrosis. N Engl J Med 2012; 367:879-881.
    • (2012) N Engl J Med , vol.367 , pp. 879-881
    • Siegal, D.M.1    Cook, R.J.2    Warkentin, T.E.3
  • 55
    • 84890467615 scopus 로고    scopus 로고
    • Anticoagulant failure in coagulopathic patients: PTT confounding and other pitfalls
    • Warkentin TE. Anticoagulant failure in coagulopathic patients: PTT confounding and other pitfalls. Exp Opin Drug Saf 2014; 13:25-43.
    • (2014) Exp Opin Drug Saf , vol.13 , pp. 25-43
    • Warkentin, T.E.1
  • 56
    • 84928493151 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia in critically ill patients
    • Warkentin TE. Heparin-induced thrombocytopenia in critically ill patients. Semin Thromb Hemost 2015; 41:49-60.
    • (2015) Semin Thromb Hemost , vol.41 , pp. 49-60
    • Warkentin, T.E.1
  • 57
    • 73049094086 scopus 로고    scopus 로고
    • Early-onset and persisting thrombo-cytopenia in postcardiac surgery patients is rarely due to heparin-induced thrombocytopenia, even when antibody tests are positive
    • Selleng S, Malowsky B, Strobel U, et al. Early-onset and persisting thrombo-cytopenia in postcardiac surgery patients is rarely due to heparin-induced thrombocytopenia, even when antibody tests are positive. J Thromb Haemost 2010; 8:30-36.
    • (2010) J Thromb Haemost , vol.8 , pp. 30-36
    • Selleng, S.1    Malowsky, B.2    Strobel, U.3
  • 58
    • 39549110000 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia in patients requiring prolonged intensive care unit treatment after cardiopul-monary bypass
    • Selleng S, Selleng K, Wollert HG, et al. Heparin-induced thrombocytopenia in patients requiring prolonged intensive care unit treatment after cardiopul-monary bypass. J Thromb Haemost 2007; 6:428-435.
    • (2007) J Thromb Haemost , vol.6 , pp. 428-435
    • Selleng, S.1    Selleng, K.2    Wollert, H.G.3
  • 59
    • 84865344043 scopus 로고    scopus 로고
    • The serological profile of early-onset and persisting postcardiac surgery thrombocytopenia complicated by "true" heparin-induced thrombocytopenia
    • Warkentin TE, Moore JC, Vogel S, et al. The serological profile of early-onset and persisting postcardiac surgery thrombocytopenia complicated by "true" heparin-induced thrombocytopenia. Thromb Haemost 2012; 107:998-1000.
    • (2012) Thromb Haemost , vol.107 , pp. 998-1000
    • Warkentin, T.E.1    Moore, J.C.2    Vogel, S.3
  • 60
    • 84867136859 scopus 로고    scopus 로고
    • Clinical and biological features of patients suspected or confirmed to have heparin-induced throm-bocytopenia in a cardiothoracic surgical ICU
    • Trehel-Tursis V, Louvain-Quintard V, Zarrouki Y, et al. Clinical and biological features of patients suspected or confirmed to have heparin-induced throm-bocytopenia in a cardiothoracic surgical ICU. Chest 2012; 142:837-844.
    • (2012) Chest , vol.142 , pp. 837-844
    • Trehel-Tursis, V.1    Louvain-Quintard, V.2    Zarrouki, Y.3
  • 61
    • 84867126714 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia in the ICU: A transatlantic perspective
    • Warkentin TE. Heparin-induced thrombocytopenia in the ICU: a transatlantic perspective. Chest 2012; 142:815-816.
    • (2012) Chest , vol.142 , pp. 815-816
    • Warkentin, T.E.1
  • 62
    • 84929519273 scopus 로고    scopus 로고
    • Prevalence and clinical implications of anti-PF4/heparin antibodies in intensive care patients: A prospective observational study
    • Selleng S, Selleng K, Friesecke S, et al. Prevalence and clinical implications of anti-PF4/heparin antibodies in intensive care patients: a prospective observational study. J Thromb Thrombolysis 2015; 39:60-67.
    • (2015) J Thromb Thrombolysis , vol.39 , pp. 60-67
    • Selleng, S.1    Selleng, K.2    Friesecke, S.3
  • 63
    • 77957937073 scopus 로고    scopus 로고
    • Heparin-platelet factor 4 antibodies in intensive care unit patients: An observational seroprevalence study
    • Levine RL, Hergenroeder GW, Francis JL, et al. Heparin-platelet factor 4 antibodies in intensive care unit patients: an observational seroprevalence study. J Thromb Thrombolysis 2010; 30:142-148.
    • (2010) J Thromb Thrombolysis , vol.30 , pp. 142-148
    • Levine, R.L.1    Hergenroeder, G.W.2    Francis, J.L.3
  • 64
    • 79959504577 scopus 로고    scopus 로고
    • Overdiagnosis of heparin-induced thrombocytopenia in surgical ICU patients
    • Berry C, Tcherniantchouk O, Ley EJ, et al. Overdiagnosis of heparin-induced thrombocytopenia in surgical ICU patients. J Am Coll Surg 2011; 213:10-17.
    • (2011) J Am Coll Surg , vol.213 , pp. 10-17
    • Berry, C.1    Tcherniantchouk, O.2    Ley, E.J.3
  • 65
    • 36749095644 scopus 로고    scopus 로고
    • What is the potential for overdiagnosis of heparin-induced thrombocytopenia?
    • Lo GK, Sigouin CS, Warkentin TE. What is the potential for overdiagnosis of heparin-induced thrombocytopenia? Am J Hematol 2007; 82:1037-1043.
    • (2007) Am J Hematol , vol.82 , pp. 1037-1043
    • Lo, G.K.1    Sigouin, C.S.2    Warkentin, T.E.3
  • 66
    • 45949112509 scopus 로고    scopus 로고
    • Quantitative interpretation of optical density measurements using PF4-dependent enzyme-immunoassays
    • Warkentin TE, Sheppard JI, Moore JC, et al. Quantitative interpretation of optical density measurements using PF4-dependent enzyme-immunoassays. J Thromb Haemost 2008; 6:1304-1312.
    • (2008) J Thromb Haemost , vol.6 , pp. 1304-1312
    • Warkentin, T.E.1    Sheppard, J.I.2    Moore, J.C.3
  • 67
    • 27144527501 scopus 로고    scopus 로고
    • Risk for heparin-induced thrombocytopenia with unfractionated and low-molecular-weight heparin thromboprophylaxis: A meta-analysis
    • Martel N, Lee J, Wells PS. Risk for heparin-induced thrombocytopenia with unfractionated and low-molecular-weight heparin thromboprophylaxis: a meta-analysis. Blood 2005; 106:2710-2715.
    • (2005) Blood , vol.106 , pp. 2710-2715
    • Martel, N.1    Lee, J.2    Wells, P.S.3
  • 68
    • 33751161450 scopus 로고    scopus 로고
    • Gender imbalance and risk factor interactions in heparin-induced thrombocytopenia
    • Warkentin TE, Sheppard JI, Sigouin CS, et al. Gender imbalance and risk factor interactions in heparin-induced thrombocytopenia. Blood 2006; 108:2937-2941.
    • (2006) Blood , vol.108 , pp. 2937-2941
    • Warkentin, T.E.1    Sheppard, J.I.2    Sigouin, C.S.3
  • 69
    • 77950356215 scopus 로고    scopus 로고
    • The severity of trauma determines the immune response to PF4/heparin and the frequency of heparin-induced thrombocytopenia
    • Lubenow N, Hinz P, Thomaschewski S, et al. The severity of trauma determines the immune response to PF4/heparin and the frequency of heparin-induced thrombocytopenia. Blood 2010; 115:1797-1803.
    • (2010) Blood , vol.115 , pp. 1797-1803
    • Lubenow, N.1    Hinz, P.2    Thomaschewski, S.3
  • 70
    • 84884321139 scopus 로고    scopus 로고
    • Heparin-induced throm-bocytopenia in medical surgical critical illness
    • Warkentin TE, Sheppard JI, Heels-Ansdell D, et al. Heparin-induced throm-bocytopenia in medical surgical critical illness. Chest 2013; 144:848-858.
    • (2013) Chest , vol.144 , pp. 848-858
    • Warkentin, T.E.1    Sheppard, J.I.2    Heels-Ansdell, D.3
  • 71
    • 79953797206 scopus 로고    scopus 로고
    • Dalteparin versus unfractionated heparin in critically ill patients
    • PROTECT Investigators for the Canadian Critical Care Trials Group and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Cook D, Meade M, Guyatt G, et al. Dalteparin versus unfractionated heparin in critically ill patients. N Engl J Med 2011; 364:1305-1314.
    • (2011) N Engl J Med , vol.364 , pp. 1305-1314
    • Cook, D.1    Meade, M.2    Guyatt, G.3
  • 72
    • 0033580605 scopus 로고    scopus 로고
    • Antibodies to platelet factor 4-heparin after cardiopulmonary bypass in patients anticoagulated with unfractionated heparin or a low-molecular-weight heparin: Clinical implications for heparin-induced thrombocytopenia
    • Pouplard C, May MA, Iochmann S, et al. Antibodies to platelet factor 4-heparin after cardiopulmonary bypass in patients anticoagulated with unfractionated heparin or a low-molecular-weight heparin: clinical implications for heparin-induced thrombocytopenia. Circulation 1999; 99:2530-2536.
    • (1999) Circulation , vol.99 , pp. 2530-2536
    • Pouplard, C.1    May, M.A.2    Iochmann, S.3
  • 73
    • 15944398977 scopus 로고    scopus 로고
    • Changes in platelet count after cardiac surgery can effectively predict the development of pathogenic heparin-dependent antibodies
    • Pouplard C, May MA, Regina S, et al. Changes in platelet count after cardiac surgery can effectively predict the development of pathogenic heparin-dependent antibodies. Br J Haematol 2005; 128:837-884.
    • (2005) Br J Haematol , vol.128 , pp. 837-884
    • Pouplard, C.1    May, M.A.2    Regina, S.3
  • 74
    • 42949127775 scopus 로고    scopus 로고
    • Prophylaxis against deep vein thrombosis in critically ill patients with severe renal insufficiency with the low-molecular-weight heparin dalteparin: The DIRECT study
    • Douketis J, Cook DJ, Meade M, et al. Prophylaxis against deep vein thrombosis in critically ill patients with severe renal insufficiency with the low-molecular-weight heparin dalteparin: the DIRECT study. Arch Intern Med 2008; 168:1805-1812.
    • (2008) Arch Intern Med , vol.168 , pp. 1805-1812
    • Douketis, J.1    Cook, D.J.2    Meade, M.3
  • 75
    • 28444474894 scopus 로고    scopus 로고
    • Dalteparin thromboprophylaxis for critically ill medical-surgical patients with renal insufficiency
    • Rabbat CG, Cook DJ, Crowther MA, et al. Dalteparin thromboprophylaxis for critically ill medical-surgical patients with renal insufficiency. J Crit Care 2005; 20:357-363.
    • (2005) J Crit Care , vol.20 , pp. 357-363
    • Rabbat, C.G.1    Cook, D.J.2    Crowther, M.A.3
  • 76
    • 33644989189 scopus 로고    scopus 로고
    • Should Vitamin K be administered when HIT is diagnosed after administration of coumarin?
    • Warkentin TE. Should vitamin K be administered when HIT is diagnosed after administration of coumarin? J Thromb Haemost 2006; 4:894-896.
    • (2006) J Thromb Haemost , vol.4 , pp. 894-896
    • Warkentin, T.E.1
  • 77
    • 84856792328 scopus 로고    scopus 로고
    • Treatment and prevention of heparin-induced thrombocytopenia: Antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines
    • Linkins LA, Dans AL, Moores LK, et al. Treatment and prevention of heparin-induced thrombocytopenia: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 2012; 141 (2 Suppl):e495S-e530S.
    • (2012) Chest , vol.141 , Issue.2 , pp. e495S-e530S
    • Linkins, L.A.1    Dans, A.L.2    Moores, L.K.3
  • 78
    • 52949118429 scopus 로고    scopus 로고
    • Platelet transfusions in heparin-induced throm-bocytopenia: A report of four cases and review of the literature
    • Hopkins CK, Goldfinger D. Platelet transfusions in heparin-induced throm-bocytopenia: a report of four cases and review of the literature. Transfusion 2008; 48:2128-2132.
    • (2008) Transfusion , vol.48 , pp. 2128-2132
    • Hopkins, C.K.1    Goldfinger, D.2
  • 79
    • 77954521462 scopus 로고    scopus 로고
    • Outcomes after platelet transfusion in patients with heparin-induced thrombocytopenia
    • Refaai MA, Chuang C, Menegus M, et al. Outcomes after platelet transfusion in patients with heparin-induced thrombocytopenia. J Thromb Haemost 2010; 8:1419-1421.
    • (2010) J Thromb Haemost , vol.8 , pp. 1419-1421
    • Refaai, M.A.1    Chuang, C.2    Menegus, M.3
  • 80
    • 84923859033 scopus 로고    scopus 로고
    • Platelet transfusions in platelet consumptive disorders are associated with arterial thrombosis and in-hospital mortality
    • Goel R, Ness PM, Takemoto CM, et al. Platelet transfusions in platelet consumptive disorders are associated with arterial thrombosis and in-hospital mortality. Blood 2015; 125:1470-1476.
    • (2015) Blood , vol.125 , pp. 1470-1476
    • Goel, R.1    Ness, P.M.2    Takemoto, C.M.3
  • 81
    • 58149115520 scopus 로고    scopus 로고
    • Predictors of clinical outcome in patients with heparin-induced thrombocytopenia treated with direct thrombin inhibitors
    • Kelton JG, Hursting MJ, Heddle N, Lewis BE. Predictors of clinical outcome in patients with heparin-induced thrombocytopenia treated with direct thrombin inhibitors. Blood Coagul Fibrinolysis 2008; 19:471-475.
    • (2008) Blood Coagul Fibrinolysis , vol.19 , pp. 471-475
    • Kelton, J.G.1    Hursting, M.J.2    Heddle, N.3    Lewis, B.E.4
  • 82
    • 84902031482 scopus 로고    scopus 로고
    • Treatment of heparin-induced thrombocytope-nia: An overview
    • Warkentin TE, Greinacher A, editors Boca Raton, FL: CRC Press [Accessed 28 Sep 2015]
    • Greinacher A, Warkentin TE. Treatment of heparin-induced thrombocytope-nia: an overview. In: Warkentin TE, Greinacher A, editors. Heparin-induced thrombocytopenia, 5th ed. Boca Raton, FL: CRC Press; 2013. pp. 315-355. http://www.hospira.com/en/images/EN-3339-tcm81-92293.pdf [Accessed 28 Sep 2015]
    • (2013) Heparin-induced Thrombocytopenia, 5th Ed , pp. 315-355
    • Greinacher, A.1    Warkentin, T.E.2
  • 83
    • 85027914213 scopus 로고    scopus 로고
    • Progressive, fatal thrombosis associated with heparin-induced thrombocytopenia following cardiac surgery despite "therapeutic" anticoagulation with argatroban: Potential role for PTT and ACT confounding
    • Aug 25 [Epub ahead of print]
    • Smythe MA, Forsyth LL, Warkentin TE, et al. Progressive, fatal thrombosis associated with heparin-induced thrombocytopenia following cardiac surgery despite "therapeutic" anticoagulation with argatroban: potential role for PTT and ACT confounding. J Thorac Cardiovasc Anesth 2014; Aug 25. [Epub ahead of print]
    • (2014) J Thorac Cardiovasc Anesth
    • Smythe, M.A.1    Forsyth, L.L.2    Warkentin, T.E.3
  • 84
    • 0035836541 scopus 로고    scopus 로고
    • Argatroban anticoagulant therapy in patients with heparin-induced thrombocytopenia
    • Lewis BE, Wallis DE, Berkowitz SD, et al. Argatroban anticoagulant therapy in patients with heparin-induced thrombocytopenia. Circulation 2001; 103:1838-1843.
    • (2001) Circulation , vol.103 , pp. 1838-1843
    • Lewis, B.E.1    Wallis, D.E.2    Berkowitz, S.D.3
  • 85
    • 0038285887 scopus 로고    scopus 로고
    • Argatroban anticoagulation in patients with heparin-induced thrombocytopenia
    • Lewis BE, Wallis DE, Leya F, et al. Argatroban anticoagulation in patients with heparin-induced thrombocytopenia. Arch Intern Med 2003; 163:1849-1856.
    • (2003) Arch Intern Med , vol.163 , pp. 1849-1856
    • Lewis, B.E.1    Wallis, D.E.2    Leya, F.3
  • 86
    • 0036733708 scopus 로고    scopus 로고
    • Venous limb gangrene during overlapping therapy with warfarin and a direct thrombin inhibitor for immune heparin-induced thrombocytopenia
    • Smythe MA, Warkentin TE, Stephens JL, et al. Venous limb gangrene during overlapping therapy with warfarin and a direct thrombin inhibitor for immune heparin-induced thrombocytopenia. Am J Hematol 2002; 71:50-52.
    • (2002) Am J Hematol , vol.71 , pp. 50-52
    • Smythe, M.A.1    Warkentin, T.E.2    Stephens, J.L.3
  • 87
    • 84902028536 scopus 로고    scopus 로고
    • Coumarin-induced skin necrosis and venous limb gangrene
    • Marder VJ, Aird WC, Bennett JS, et al., editors Philadelphia: Lippincott Williams & Wilkins
    • Warkentin TE. Coumarin-induced skin necrosis and venous limb gangrene. In: Marder VJ, Aird WC, Bennett JS, et al., editors. Hemostasis and thrombosis: basic principles and clinical practice, 6th ed. Philadelphia: Lippincott Williams & Wilkins; 2013. pp. 1308-1317.
    • (2013) Hemostasis and Thrombosis: Basic Principles and Clinical Practice, 6th Ed , pp. 1308-1317
    • Warkentin, T.E.1
  • 88
    • 27844481103 scopus 로고    scopus 로고
    • Differences in the clinically effective molar concentrations of four direct thrombin inhibitors explain their variable prothrombin time prolongation
    • Warkentin TE, Greinacher A, Craven S, et al. Differences in the clinically effective molar concentrations of four direct thrombin inhibitors explain their variable prothrombin time prolongation. Thromb Haemost 2005; 94:958-964.
    • (2005) Thromb Haemost , vol.94 , pp. 958-964
    • Warkentin, T.E.1    Greinacher, A.2    Craven, S.3
  • 89
    • 84902548645 scopus 로고    scopus 로고
    • Frequent off-label use of fondaparinux in patients with suspected acute heparin-induced thrombocy-topenia (HIT)-findings from the GerHIT multicentre registry study
    • Schindewolf M, Steindl J, Beyer-Westendorf J. Frequent off-label use of fondaparinux in patients with suspected acute heparin-induced thrombocy-topenia (HIT)-findings from the GerHIT multicentre registry study. Thromb Res 2014; 134:29-35.
    • (2014) Thromb Res , vol.134 , pp. 29-35
    • Schindewolf, M.1    Steindl, J.2    Beyer-Westendorf, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.