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Volumn 116, Issue 23, 2010, Pages 5021-5031

Monocyte-bound PF4 in the pathogenesis of heparin-induced thrombocytopenia

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSAMINOGLYCAN; THROMBOCYTE FACTOR 4;

EID: 78649742009     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-03-276964     Document Type: Article
Times cited : (118)

References (50)
  • 1
    • 0022262953 scopus 로고
    • The interaction of platelet factor four and glycosaminoglycans
    • DOI 10.1016/0003-9861(85)90049-9
    • Loscalzo J, Melnick B, Handin RI. The interaction of platelet factor four and glycosaminoglycans. Arch Biochem Biophys. 1985;240(1):446-455. (Pubitemid 15008710)
    • (1985) Archives of Biochemistry and Biophysics , vol.240 , Issue.1 , pp. 446-455
    • Loscalzo, J.1    Melnick, B.2    Handin, R.I.3
  • 2
    • 0020034287 scopus 로고
    • Human platelet surface binding of endogenous secreted factor VIII-von Willebrand factor and platelet factor 4
    • George JN, Onofre AR. Human platelet surface binding of endogenous secreted factor VIII-von Willebrand factor and platelet factor 4. Blood. 1982;59(1):194-197.
    • (1982) Blood , vol.59 , Issue.1 , pp. 194-197
    • George, J.N.1    Onofre, A.R.2
  • 3
    • 0020570419 scopus 로고
    • Effect of heparin on the in vivo release and clearance of human platelet factor 4
    • Rao AK, Niewiarowski S, James P, et al. Effect of heparin on the in vivo release and clearance of human platelet factor 4. Blood. 1983;61(6):1208-1214.
    • (1983) Blood , vol.61 , Issue.6 , pp. 1208-1214
    • Rao, A.K.1    Niewiarowski, S.2    James, P.3
  • 4
    • 0026638091 scopus 로고
    • Platelet factor 4 complexed to heparin is the target for antibodies generated in heparin-induced thrombocytopenia
    • Amiral J, Bridey F, Dreyfus M, et al. Platelet factor 4 complexed to heparin is the target for antibodies generated in heparin-induced thrombocytopenia. Thromb Haemost. 1992;68(1):95-96.
    • (1992) Thromb Haemost , vol.68 , Issue.1 , pp. 95-96
    • Amiral, J.1    Bridey, F.2    Dreyfus, M.3
  • 5
    • 0028014541 scopus 로고
    • Heparin-associated thrombocytopenia: Isolation of the antibody and characterization of a multimolecular PF4-heparin complex as the major antigen
    • Greinacher A, Potzsch B, Amiral J, Dummel V, Eichner A, Mueller-Eckhardt C. Heparin-associated thrombocytopenia: isolation of the antibody and characterization of a multimolecular PF4-heparin complex as the major antigen. Thromb Haemost. 1994;71(2):247-251.
    • (1994) Thromb Haemost , vol.71 , Issue.2 , pp. 247-251
    • Greinacher, A.1    Potzsch, B.2    Amiral, J.3    Dummel, V.4    Eichner, A.5    Mueller-Eckhardt, C.6
  • 6
    • 39649122158 scopus 로고    scopus 로고
    • Determinants of PF4/heparin immunogenicity
    • Suvarna S, Espinasse B, Qi R, et al. Determinants of PF4/heparin immunogenicity. Blood. 2007;110(13):4253-4260.
    • (2007) Blood , vol.110 , Issue.13 , pp. 4253-4260
    • Suvarna, S.1    Espinasse, B.2    Qi, R.3
  • 7
    • 11144238284 scopus 로고    scopus 로고
    • Ultralarge complexes of PF4 and heparin are central to the pathogenesis of heparin-induced thrombocytopenia
    • Rauova L, Poncz M, McKenzie SE, et al. Ultralarge complexes of PF4 and heparin are central to the pathogenesis of heparin-induced thrombocytopenia. Blood. 2005;105(1):131-138.
    • (2005) Blood , vol.105 , Issue.1 , pp. 131-138
    • Rauova, L.1    Poncz, M.2    McKenzie, S.E.3
  • 8
    • 33644745161 scopus 로고    scopus 로고
    • Role of platelet surface PF4 antigenic complexes in heparin-induced thrombocytopenia pathogenesis: Diagnostic and therapeutic implications
    • Rauova L, Zhai L, Kowalska MA, Arepally GM, Cines DB, Poncz M. Role of platelet surface PF4 antigenic complexes in heparin-induced thrombocytopenia pathogenesis: diagnostic and therapeutic implications. Blood. 2006;107(6):2346-2353.
    • (2006) Blood , vol.107 , Issue.6 , pp. 2346-2353
    • Rauova, L.1    Zhai, L.2    Kowalska, M.A.3    Arepally, G.M.4    Cines, D.B.5    Poncz, M.6
  • 9
    • 0025743919 scopus 로고
    • Characterization of a heparan sulfate and a peculiar chondroitin 4-sulfate proteoglycan from platelets. Inhibition of the aggregation process by platelet chondroitin sulfate proteoglycan
    • Nader HB. Characterization of a heparan sulfate and a peculiar chondroitin 4-sulfate proteoglycan from platelets. Inhibition of the aggregation process by platelet chondroitin sulfate proteoglycan. J Biol Chem. 1991;266(16):10518-10523.
    • (1991) J Biol Chem , vol.266 , Issue.16 , pp. 10518-10523
    • Nader, H.B.1
  • 10
    • 0018403268 scopus 로고
    • Characterization of the sulfated glycosaminoglycan on the surface and in the storage granules of rabbit platelets
    • Ward JV, Packham MA. Characterization of the sulfated glycosaminoglycan on the surface and in the storage granules of rabbit platelets. Biochim Biophys Acta. 1979;583(2):196-207.
    • (1979) Biochim Biophys Acta , vol.583 , Issue.2 , pp. 196-207
    • Ward, J.V.1    Packham, M.A.2
  • 11
    • 17644438477 scopus 로고    scopus 로고
    • Characterization of a murine monoclonal antibody that mimics heparin-induced thrombocytopenia antibodies
    • Arepally GM, Kamei S, Park KS, et al. Characterization of a murine monoclonal antibody that mimics heparin-induced thrombocytopenia antibodies. Blood. 2000;95(5):1533-1540.
    • (2000) Blood , vol.95 , Issue.5 , pp. 1533-1540
    • Arepally, G.M.1    Kamei, S.2    Park, K.S.3
  • 12
    • 33947132649 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: An autoimmune disorder regulated through dynamic autoantigen assembly/disassembly
    • Cines DB, Rauova L, Arepally G, et al. Heparin-induced thrombocytopenia: an autoimmune disorder regulated through dynamic autoantigen assembly/disassembly. J Clin Apher. 2007;22(1):31-36.
    • (2007) J Clin Apher , vol.22 , Issue.1 , pp. 31-36
    • Cines, D.B.1    Rauova, L.2    Arepally, G.3
  • 13
    • 1442265917 scopus 로고    scopus 로고
    • Pathogenesis of heparin-induced thrombocytopenia and thrombosis
    • Arepally G, Cines DB. Pathogenesis of heparin-induced thrombocytopenia and thrombosis. Autoimmun Rev. 2002;1(3):125-132.
    • (2002) Autoimmun Rev , vol.1 , Issue.3 , pp. 125-132
    • Arepally, G.1    Cines, D.B.2
  • 15
    • 0034235911 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: New evidence for the dynamic binding of purified anti-PF4-heparin antibodies to platelets and the resultant platelet activation
    • Newman PM, Chong BH. Heparin-induced thrombocytopenia: new evidence for the dynamic binding of purified anti-PF4-heparin antibodies to platelets and the resultant platelet activation. Blood. 2000;96(1):182-187.
    • (2000) Blood , vol.96 , Issue.1 , pp. 182-187
    • Newman, P.M.1    Chong, B.H.2
  • 16
    • 77950356215 scopus 로고    scopus 로고
    • The severity of trauma determines the immune response to PF4/heparin and the frequency of heparin-induced thrombocytopenia
    • Lubenow N, Hinz P, Thomaschewski S, et al. The severity of trauma determines the immune response to PF4/heparin and the frequency of heparin-induced thrombocytopenia. Blood. 2010;115(9):1797-1803.
    • (2010) Blood , vol.115 , Issue.9 , pp. 1797-1803
    • Lubenow, N.1    Hinz, P.2    Thomaschewski, S.3
  • 17
    • 22144446420 scopus 로고    scopus 로고
    • Clinical features of heparin-induced thrombocytopenia including risk factors for thrombosis. A retrospective analysis of 408 patients
    • Greinacher A, Farner B, Kroll H, Kohlmann T, Warkentin TE, Eichler P. Clinical features of heparin-induced thrombocytopenia including risk factors for thrombosis. A retrospective analysis of 408 patients. Thromb Haemost. 2005;94(1):132-135.
    • (2005) Thromb Haemost , vol.94 , Issue.1 , pp. 132-135
    • Greinacher, A.1    Farner, B.2    Kroll, H.3    Kohlmann, T.4    Warkentin, T.E.5    Eichler, P.6
  • 18
    • 0034971216 scopus 로고    scopus 로고
    • A new approach in the study of the molecular and cellular events implicated in heparin-induced thrombocytopenia: Formation of leukocyte-platelet aggregates
    • Khairy M, Lasne D, Brohard-Bohn B, Aiach M, Rendu F, Bachelot-Loza C. A new approach in the study of the molecular and cellular events implicated in heparin-induced thrombocytopenia. Formation of leukocyte-platelet aggregates. Thromb Haemost. 2001;85(6):1090-1096. (Pubitemid 32573765)
    • (2001) Thrombosis and Haemostasis , vol.85 , Issue.6 , pp. 1090-1096
    • Khairy, M.1    Lasne, D.2    Brohard-Bohn, B.3    Aiach, M.4    Rendu, F.5    Bachelot-Loza, C.6
  • 19
    • 10444223030 scopus 로고    scopus 로고
    • Polymorphonuclear leukocyte and monocyte activation induced by plasma from patients with heparin-induced thrombocytopenia in whole blood
    • Khairy M, Lasne D, Amelot A, et al. Polymorphonuclear leukocyte and monocyte activation induced by plasma from patients with heparin-induced thrombocytopenia in whole blood. Thromb Haemost. 2004;92(6):1411-1419.
    • (2004) Thromb Haemost , vol.92 , Issue.6 , pp. 1411-1419
    • Khairy, M.1    Lasne, D.2    Amelot, A.3
  • 20
    • 51649114878 scopus 로고    scopus 로고
    • Immune complexes formed following the binding of anti-platelet factor 4 (CXCL4) antibodies to CXCL4 stimulate human neutrophil activation and cell adhesion
    • Xiao Z, Visentin GP, Dayananda KM, Neelamegham S. Immune complexes formed following the binding of anti-platelet factor 4 (CXCL4) antibodies to CXCL4 stimulate human neutrophil activation and cell adhesion. Blood. 2008;112(4):1091-1100.
    • (2008) Blood , vol.112 , Issue.4 , pp. 1091-1100
    • Xiao, Z.1    Visentin, G.P.2    Dayananda, K.M.3    Neelamegham, S.4
  • 21
    • 0023109003 scopus 로고
    • Immune endothelial-cell injury in heparin-associated thrombocytopenia
    • Cines DB, Tomaski A, Tannenbaum S. Immune endothelial-cell injury in heparin-associated thrombocytopenia. N Engl J Med. 1987;316(10):581-589.
    • (1987) N Engl J Med , vol.316 , Issue.10 , pp. 581-589
    • Cines, D.B.1    Tomaski, A.2    Tannenbaum, S.3
  • 22
    • 0035883078 scopus 로고    scopus 로고
    • Antibodies from patients with heparin-induced thrombocytopenia stimulate monocytic cells to express tissue factor and secrete interleukin-8
    • Arepally GM, Mayer IM. Antibodies from patients with heparin-induced thrombocytopenia stimulate monocytic cells to express tissue factor and secrete interleukin-8. Blood. 2001;98(4):1252-1254.
    • (2001) Blood , vol.98 , Issue.4 , pp. 1252-1254
    • Arepally, G.M.1    Mayer, I.M.2
  • 23
    • 0035874509 scopus 로고    scopus 로고
    • Induction of monocyte tissue factor expression by antibodies to heparin-platelet factor 4 complexes developed in heparin-induced thrombocytopenia
    • Pouplard C, Iochmann S, Renard B, et al. Induction of monocyte tissue factor expression by antibodies to heparin-platelet factor 4 complexes developed in heparin-induced thrombocytopenia. Blood. 2001;97(10):3300-3302.
    • (2001) Blood , vol.97 , Issue.10 , pp. 3300-3302
    • Pouplard, C.1    Iochmann, S.2    Renard, B.3
  • 24
    • 44849134171 scopus 로고    scopus 로고
    • Monocyte cell surface glycosaminoglycans positively modulate IL-4-induced differentiation toward dendritic cells
    • den Dekker E, Grefte S, Huijs T, et al. Monocyte cell surface glycosaminoglycans positively modulate IL-4-induced differentiation toward dendritic cells. J Immunol. 2008;180(6):3680-3688.
    • (2008) J Immunol , vol.180 , Issue.6 , pp. 3680-3688
    • Den Dekker, E.1    Grefte, S.2    Huijs, T.3
  • 25
    • 33744500203 scopus 로고    scopus 로고
    • Cell surface proteoglycan expression during maturation of human monocytes-derived dendritic cells and macrophages
    • Wegrowski Y, Milard AL, Kotlarz G, Toulmonde E, Maquart FX, Bernard J. Cell surface proteoglycan expression during maturation of human monocytes-derived dendritic cells and macrophages. Clin Exp Immunol. 2006;144(3):485-493.
    • (2006) Clin Exp Immunol , vol.144 , Issue.3 , pp. 485-493
    • Wegrowski, Y.1    Milard, A.L.2    Kotlarz, G.3    Toulmonde, E.4    Maquart, F.X.5    Bernard, J.6
  • 26
    • 0025369132 scopus 로고
    • Proteoglycans synthesized in vitro by nude and normal mouse peritoneal macrophages
    • Petricevich VL, Michelacci YM. Proteoglycans synthesized in vitro by nude and normal mouse peritoneal macrophages. Biochim Biophys Acta. 1990;1053(2-3):135-143.
    • (1990) Biochim Biophys Acta , vol.1053 , Issue.2-3 , pp. 135-143
    • Petricevich, V.L.1    Michelacci, Y.M.2
  • 27
    • 0025241790 scopus 로고
    • Biologic and biochemic properties of recombinant platelet factor 4 demonstrate identity with the native protein
    • Park KS, Rifat S, Eck H, Adachi K, Surrey S, Poncz M. Biologic and biochemic properties of recombinant platelet factor 4 demonstrate identity with the native protein. Blood. 1990;75(6):1290-1295.
    • (1990) Blood , vol.75 , Issue.6 , pp. 1290-1295
    • Park, K.S.1    Rifat, S.2    Eck, H.3    Adachi, K.4    Surrey, S.5    Poncz, M.6
  • 28
    • 0027287789 scopus 로고
    • Leishmania antigens presented by GM-CSF-derived macrophages protect susceptible mice against challenge with Leishmania major
    • Doherty TM, Coffman RL. Leishmania antigens presented by GM-CSF-derived macrophages protect susceptible mice against challenge with Leishmania major. J Immunol. 1993;150(12):5476-5483.
    • (1993) J Immunol , vol.150 , Issue.12 , pp. 5476-5483
    • Doherty, T.M.1    Coffman, R.L.2
  • 29
    • 0035168403 scopus 로고    scopus 로고
    • New mechanisms and pathways for monocyte recruitment
    • Muller WA. New mechanisms and pathways for monocyte recruitment. J Exp Med. 2001;194(9):F47-51.
    • (2001) J Exp Med , vol.194 , Issue.9
    • Muller, W.A.1
  • 30
    • 51349149624 scopus 로고    scopus 로고
    • Surfen, a small molecule antagonist of heparan sulfate
    • Schuksz M, Fuster MM, Brown JR, et al. Surfen, a small molecule antagonist of heparan sulfate. Proc Natl Acad Sci U S A. 2008;105(35):13075- 13080.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.35 , pp. 13075-13080
    • Schuksz, M.1    Fuster, M.M.2    Brown, J.R.3
  • 31
    • 0035437186 scopus 로고    scopus 로고
    • Localization of distal regulatory domains in the megakaryocyte-specific platelet basic protein/platelet factor 4 gene locus
    • Zhang C, Thornton MA, Kowalska MA, et al. Localization of distal regulatory domains in the megakaryocyte-specific platelet basic protein/platelet factor 4 gene locus. Blood. 2001;98(3):610-617.
    • (2001) Blood , vol.98 , Issue.3 , pp. 610-617
    • Zhang, C.1    Thornton, M.A.2    Kowalska, M.A.3
  • 32
    • 3843072270 scopus 로고    scopus 로고
    • Transgenic mice studies demonstrate a role for platelet factor 4 in thrombosis: Dissociation between anticoagulant and antithrombotic effect of heparin
    • Eslin DE, Zhang C, Samuels KJ, et al. Transgenic mice studies demonstrate a role for platelet factor 4 in thrombosis: dissociation between anticoagulant and antithrombotic effect of heparin. Blood. 2004;104(10):3173-3180.
    • (2004) Blood , vol.104 , Issue.10 , pp. 3173-3180
    • Eslin, D.E.1    Zhang, C.2    Samuels, K.J.3
  • 33
    • 0033120914 scopus 로고    scopus 로고
    • The role of the human Fc receptor Fc gamma RIIA in the immune clearance of platelets: A transgenic mouse model
    • McKenzie SE, Taylor SM, Malladi P, et al. The role of the human Fc receptor Fc gamma RIIA in the immune clearance of platelets: a transgenic mouse model. J Immunol. 1999;162(7):4311-4318.
    • (1999) J Immunol , vol.162 , Issue.7 , pp. 4311-4318
    • McKenzie, S.E.1    Taylor, S.M.2    Malladi, P.3
  • 34
    • 1642406217 scopus 로고    scopus 로고
    • Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response
    • Sunderkotter C, Nikolic T, Dillon MJ, et al. Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response. J Immunol. 2004;172(7):4410-4417.
    • (2004) J Immunol , vol.172 , Issue.7 , pp. 4410-4417
    • Sunderkotter, C.1    Nikolic, T.2    Dillon, M.J.3
  • 35
    • 0026728411 scopus 로고
    • Heterogeneity of rat liver and spleen macrophages in gadolinium chloride-induced elimination and repopulation
    • Hardonk MJ, Dijkhuis FW, Hulstaert CE, Koudstaal J. Heterogeneity of rat liver and spleen macrophages in gadolinium chloride-induced elimination and repopulation. J Leukoc Biol. 1992;52(3):296-302.
    • (1992) J Leukoc Biol , vol.52 , Issue.3 , pp. 296-302
    • Hardonk, M.J.1    Dijkhuis, F.W.2    Hulstaert, C.E.3    Koudstaal, J.4
  • 36
    • 52649093281 scopus 로고    scopus 로고
    • Macrophages contribute to the cellular uptake of von Willebrand factor and factor VIII in vivo
    • van Schooten CJ, Shahbazi S, Groot E, et al. Macrophages contribute to the cellular uptake of von Willebrand factor and factor VIII in vivo. Blood. 2008;112(5):1704-1712.
    • (2008) Blood , vol.112 , Issue.5 , pp. 1704-1712
    • Van Schooten, C.J.1    Shahbazi, S.2    Groot, E.3
  • 37
    • 0034650976 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 and vitronectin promote vascular thrombosis in mice
    • Eitzman DT, Westrick RJ, Nabel EG, Ginsburg D. Plasminogen activator inhibitor-1 and vitronectin promote vascular thrombosis in mice. Blood. 2000;95(2):577-580.
    • (2000) Blood , vol.95 , Issue.2 , pp. 577-580
    • Eitzman, D.T.1    Westrick, R.J.2    Nabel, E.G.3    Ginsburg, D.4
  • 38
    • 0141595894 scopus 로고    scopus 로고
    • Thrombus formation: Direct real-time observation and digital analysis of thrombus assembly in a living mouse by confocal and widefield intravital microscopy
    • Celi A, Merrill-Skoloff G, Gross P, et al. Thrombus formation: direct real-time observation and digital analysis of thrombus assembly in a living mouse by confocal and widefield intravital microscopy. J Thromb Haemost. 2003;1(1):60-68.
    • (2003) J Thromb Haemost , vol.1 , Issue.1 , pp. 60-68
    • Celi, A.1    Merrill-Skoloff, G.2    Gross, P.3
  • 39
    • 51649110213 scopus 로고    scopus 로고
    • Analysis of the spatial and temporal characteristics of platelet-delivered factor VIII-based clots
    • Neyman M, Gewirtz J, Poncz M. Analysis of the spatial and temporal characteristics of platelet-delivered factor VIII-based clots. Blood. 2008;112(4):1101-1108.
    • (2008) Blood , vol.112 , Issue.4 , pp. 1101-1108
    • Neyman, M.1    Gewirtz, J.2    Poncz, M.3
  • 40
    • 0025976838 scopus 로고
    • Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor
    • Yayon A, Klagsbrun M, Esko JD, Leder P, Ornitz DM. Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor. Cell. 1991;64(4):841-848. (Pubitemid 121001170)
    • (1991) Cell , vol.64 , Issue.4 , pp. 841-848
    • Yayon, A.1    Klagsbrun, M.2    Esko, J.D.3    Leder, P.4    Ornitz, D.M.5
  • 41
    • 0024467227 scopus 로고
    • Modulation of the expression of chondroitin sulfate proteoglycan in stimulated human monocytes
    • Uhlin-Hansen L, Eskeland T, Kolset SO. Modulation of the expression of chondroitin sulfate proteoglycan in stimulated human monocytes. J Biol Chem. 1989;264(25):14916-14922.
    • (1989) J Biol Chem , vol.264 , Issue.25 , pp. 14916-14922
    • Uhlin-Hansen, L.1    Eskeland, T.2    Kolset, S.O.3
  • 42
    • 22144494616 scopus 로고    scopus 로고
    • Regulated expression of platelet factor 4 in human monocytes: Role of PARs as a quantitatively important monocyte activation pathway
    • Schaffner A, Rhyn P, Schoedon G, Schaer DJ. Regulated expression of platelet factor 4 in human monocytes: role of PARs as a quantitatively important monocyte activation pathway. J Leukoc Biol. 2005;78(1):202-209.
    • (2005) J Leukoc Biol , vol.78 , Issue.1 , pp. 202-209
    • Schaffner, A.1    Rhyn, P.2    Schoedon, G.3    Schaer, D.J.4
  • 43
    • 0035889119 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia/thrombosis in a transgenic mouse model requires human platelet factor 4 and platelet activation through FcgammaRIIA
    • Reilly MP, Taylor SM, Hartman NK, et al. Heparin-induced thrombocytopenia/thrombosis in a transgenic mouse model requires human platelet factor 4 and platelet activation through FcgammaRIIA. Blood. 2001;98(8):2442-2447.
    • (2001) Blood , vol.98 , Issue.8 , pp. 2442-2447
    • Reilly, M.P.1    Taylor, S.M.2    Hartman, N.K.3
  • 44
    • 77950479716 scopus 로고    scopus 로고
    • Liposomes for specific depletion of macrophages from organs and tissues
    • van Rooijen N, Hendrikx E. Liposomes for specific depletion of macrophages from organs and tissues. Methods Mol Biol. 2010;605:189-203.
    • (2010) Methods Mol Biol , vol.605 , pp. 189-203
    • Van Rooijen, N.1    Hendrikx, E.2
  • 45
    • 0032742808 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: A clinicopathologic syndrome
    • Warkentin TE. Heparin-induced thrombocytopenia: a clinicopathologic syndrome. Thromb Haemost. 1999;82(2):439-447.
    • (1999) Thromb Haemost , vol.82 , Issue.2 , pp. 439-447
    • Warkentin, T.E.1
  • 46
    • 0029035681 scopus 로고
    • Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin
    • Warkentin TE, Levine MN, Hirsh J, et al. Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin. N Engl J Med. 1995;332(20):1330-1335.
    • (1995) N Engl J Med , vol.332 , Issue.20 , pp. 1330-1335
    • Warkentin, T.E.1    Levine, M.N.2    Hirsh, J.3
  • 47
    • 0017154001 scopus 로고
    • Purification and binding properties of human platelet factor four
    • Handin RI, Cohen HJ. Purification and binding properties of human platelet factor four. J Biol Chem. 1976;251(14):4273-4282.
    • (1976) J Biol Chem , vol.251 , Issue.14 , pp. 4273-4282
    • Handin, R.I.1    Cohen, H.J.2
  • 48
    • 0033588102 scopus 로고    scopus 로고
    • Inducible expression of the cell surface heparan sulfate proteoglycan syndecan-2 (fibroglycan) on human activated macrophages can regulate fibroblast growth factor action
    • Clasper S, Vekemans S, Fiore M, et al. Inducible expression of the cell surface heparan sulfate proteoglycan syndecan-2 (fibroglycan) on human activated macrophages can regulate fibroblast growth factor action. J Biol Chem. 1999;274(34):24113-24123.
    • (1999) J Biol Chem , vol.274 , Issue.34 , pp. 24113-24123
    • Clasper, S.1    Vekemans, S.2    Fiore, M.3
  • 49
    • 0032525207 scopus 로고    scopus 로고
    • Endothelial cells in physiology and in the pathophysiology of vascular disorders
    • Cines DB, Pollak ES, Buck CA, et al. Endothelial cells in physiology and in the pathophysiology of vascular disorders. Blood. 1998;91(10):3527-3561.
    • (1998) Blood , vol.91 , Issue.10 , pp. 3527-3561
    • Cines, D.B.1    Pollak, E.S.2    Buck, C.A.3
  • 50
    • 57749174540 scopus 로고    scopus 로고
    • Monocytes downregulate the early stage of collagen-induced platelet activation by a PECAM-1-dependent mechanism
    • Ollivier V, Arnaud B, Jandrot-Perrus M, Ajzenberg N. Monocytes downregulate the early stage of collagen-induced platelet activation by a PECAM-1-dependent mechanism. J Thromb Haemost. 2009;7(1):143-151.
    • (2009) J Thromb Haemost , vol.7 , Issue.1 , pp. 143-151
    • Ollivier, V.1    Arnaud, B.2    Jandrot-Perrus, M.3    Ajzenberg, N.4


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