An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes

Structure

Volumn 23, Issue 9, 2015, Pages 1563-1572

  Zhang, Ping ^a   Ye, Feng ^b   Bastidas, Adam C ^a   Kornev, Alexandr P ^a   Wu, Jian ^a   Ginsberg, Mark H ^b   Taylor, Susan S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; HOLOENZYME; MYRISTIC ACID; NANODISC; TETRAMER; CYCLIC AMP DEPENDENT PROTEIN KINASE REGULATORY SUBUNIT IALPHA; CYCLIC AMP DEPENDENT PROTEIN KINASE REGULATORY SUBUNIT IIBETA; ISOPROTEIN; PROTEIN BINDING;

ARTICLE; BACTERIAL GENE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ELECTRON MICROSCOPY; GENE EXPRESSION SYSTEM; GENE SWITCHING; MEMBRANE; MYRISTYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MOTIF; PROTEIN TARGETING; CHEMISTRY; ENZYME ACTIVE SITE; HUMAN; METABOLISM; MOLECULAR DOCKING; MOLECULAR MODEL; PROTEIN SECONDARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; CYCLIC AMP-DEPENDENT PROTEIN KINASE RIALPHA SUBUNIT; CYCLIC AMP-DEPENDENT PROTEIN KINASE RIIBETA SUBUNIT; HOLOENZYMES; HUMANS; MODELS, MOLECULAR; MOLECULAR DOCKING SIMULATION; MYRISTIC ACID; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN STRUCTURE, SECONDARY;

EID: 84947043161     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2015.07.007     Document Type: Article

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