-
1
-
-
73049112438
-
Worldwide Variations in Colorectal Cancer
-
Center, M. M., Jemal, A., Smith, R. A. & Ward, E. Worldwide Variations in Colorectal Cancer. CA-Cancer J. Clin. 59, 366-378 (2009).
-
(2009)
CA-Cancer J. Clin.
, vol.59
, pp. 366-378
-
-
Center, M.M.1
Jemal, A.2
Smith, R.A.3
Ward, E.4
-
2
-
-
84855792427
-
Cancer statistics, 2012
-
Siegel, R., Naishadham, D. & Jemal, A. Cancer statistics, 2012. CA Cancer J Clin 62, 10-29 (2012).
-
(2012)
CA Cancer J Clin
, vol.62
, pp. 10-29
-
-
Siegel, R.1
Naishadham, D.2
Jemal, A.3
-
3
-
-
67650999875
-
The basics of epithelial-mesenchymal transition
-
Kalluri, R. & Weinberg, R. A. The basics of epithelial-mesenchymal transition. J Clin Invest 119, 1420-1428 (2009).
-
(2009)
J Clin Invest
, vol.119
, pp. 1420-1428
-
-
Kalluri, R.1
Weinberg, R.A.2
-
4
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan, D. & Weinberg, R. A. Hallmarks of cancer: the next generation. Cell 144, 646-674 (2011).
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
5
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani, S. A. et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133, 704-715 (2008).
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
-
6
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet, D. & Dick, J. E. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat. Med. 3, 730-737 (1997).
-
(1997)
Nat. Med.
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
7
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj, M., Wicha, M. S., Benito-Hernandez, A., Morrison, S. J. & Clarke, M. F. Prospective identification of tumorigenic breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America 100, 3983-3988 (2003).
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
9
-
-
0141842674
-
Identification of a cancer stem cell in human brain tumors
-
Singh, S. K. et al. Identification of a cancer stem cell in human brain tumors. Cancer Research 63, 5821-5828 (2003).
-
(2003)
Cancer Research
, vol.63
, pp. 5821-5828
-
-
Singh, S.K.1
-
10
-
-
33846100356
-
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
-
O'Brien, C. A., Pollett, A., Gallinger, S. & Dick, J. E. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 445, 106-110 (2007).
-
(2007)
Nature
, vol.445
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
Gallinger, S.3
Dick, J.E.4
-
11
-
-
33846095137
-
Identification and expansion of human colon-cancer-initiating cells
-
Ricci-Vitiani, L. et al. Identification and expansion of human colon-cancer-initiating cells. Nature 445, 111-115 (2007).
-
(2007)
Nature
, vol.445
, pp. 111-115
-
-
Ricci-Vitiani, L.1
-
12
-
-
8444241199
-
ALCAM/CD166 is overexpressed in colorectal carcinoma and correlates with shortened patient survival
-
Weichert, W., Knosel, T., Bellach, J., Dietel, M. & Kristiansen, G. ALCAM/CD166 is overexpressed in colorectal carcinoma and correlates with shortened patient survival. J Clin Pathol 57, 1160-1164 (2004).
-
(2004)
J Clin Pathol
, vol.57
, pp. 1160-1164
-
-
Weichert, W.1
Knosel, T.2
Bellach, J.3
Dietel, M.4
Kristiansen, G.5
-
13
-
-
65949112714
-
Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis
-
Huang, E. H. et al. Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis. Cancer Res 69, 3382-3389 (2009).
-
(2009)
Cancer Res
, vol.69
, pp. 3382-3389
-
-
Huang, E.H.1
-
14
-
-
33244463813
-
Complex networks orchestrate epithelial-mesenchymal transitions
-
Thiery, J. P. & Sleeman, J. P. Complex networks orchestrate epithelial-mesenchymal transitions. Nat Rev Mol Cell Biol 7, 131-142 (2006).
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 131-142
-
-
Thiery, J.P.1
Sleeman, J.P.2
-
15
-
-
79959994448
-
SNAIL regulates interleukin-8 expression, stem cell-like activity, and tumorigenicity of human colorectal carcinoma cells
-
Hwang, W. L. et al. SNAIL regulates interleukin-8 expression, stem cell-like activity, and tumorigenicity of human colorectal carcinoma cells. Gastroenterology 141, 279-291, 291 e271-275 (2011).
-
(2011)
Gastroenterology
, vol.141
-
-
Hwang, W.L.1
-
16
-
-
70349859809
-
Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells
-
Kurrey, N. K. et al. Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells. Stem Cells 27, 2059-2068 (2009).
-
(2009)
Stem Cells
, vol.27
, pp. 2059-2068
-
-
Kurrey, N.K.1
-
17
-
-
72949104153
-
Twist modulates breast cancer stem cells by transcriptional regulation of CD24 expression
-
Vesuna, F., Lisok, A., Kimble, B. & Raman, V. Twist modulates breast cancer stem cells by transcriptional regulation of CD24 expression. Neoplasia 11, 1318-1328 (2009).
-
(2009)
Neoplasia
, vol.11
, pp. 1318-1328
-
-
Vesuna, F.1
Lisok, A.2
Kimble, B.3
Raman, V.4
-
18
-
-
73049110243
-
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
-
Wellner, U. et al. The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. Nature Cell Biology 11, 1487-U1236 (2009).
-
(2009)
Nature Cell Biology
, vol.11
, pp. 1487-U1236
-
-
Wellner, U.1
-
19
-
-
0037474235
-
Epigenetic regulation of a novel tumor suppressor gene (hDAB2IP) in prostate cancer cell lines
-
Chen, H., Toyooka, S., Gazdar, A. F. & Hsieh, J. T. Epigenetic regulation of a novel tumor suppressor gene (hDAB2IP) in prostate cancer cell lines. Journal of Biological Chemistry 278, 3121-3130 (2003).
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 3121-3130
-
-
Chen, H.1
Toyooka, S.2
Gazdar, A.F.3
Hsieh, J.T.4
-
20
-
-
20444475352
-
Down-regulation of human DAB2IP gene expression mediated by polycomb Ezh2 complex and histone deacetylase in prostate cancer
-
Chen, H., Tu, S. W. & Hsieh, J. T. Down-regulation of human DAB2IP gene expression mediated by polycomb Ezh2 complex and histone deacetylase in prostate cancer. Journal of Biological Chemistry 280, 22437-22444 (2005).
-
(2005)
Journal of Biological Chemistry
, vol.280
, pp. 22437-22444
-
-
Chen, H.1
Tu, S.W.2
Hsieh, J.T.3
-
21
-
-
20244385825
-
Aberrant promoter methylation in human DAB2 interactive protein (hDAB2IP) gene in gastrointestinal tumour
-
Dote, H. et al. Aberrant promoter methylation in human DAB2 interactive protein (hDAB2IP) gene in gastrointestinal tumour. Br. J. Cancer 92, 1117-1125 (2005).
-
(2005)
Br. J. Cancer
, vol.92
, pp. 1117-1125
-
-
Dote, H.1
-
22
-
-
12144286741
-
Aberrant promoter methylation in human DAB2 interactive protein (hDAB2IP) gene in breast cancer
-
Dote, H. et al. Aberrant promoter methylation in human DAB2 interactive protein (hDAB2IP) gene in breast cancer. Clinical Cancer Research 10, 2082-2089 (2004).
-
(2004)
Clinical Cancer Research
, vol.10
, pp. 2082-2089
-
-
Dote, H.1
-
23
-
-
33947245430
-
Differential expression of hDAB2IPA and hDAB2IPB in normal tissues and promoter methylation of hDAB2IPA in hepatocellular carcinoma
-
Qiu, G. H. et al. Differential expression of hDAB2IPA and hDAB2IPB in normal tissues and promoter methylation of hDAB2IPA in hepatocellular carcinoma. J. Hepatol. 46, 655-663 (2007).
-
(2007)
J. Hepatol.
, vol.46
, pp. 655-663
-
-
Qiu, G.H.1
-
24
-
-
8644278076
-
Aberrant promoter methylation of human DAB2 interactive protein (hDAB2IP) gene in lung cancers
-
Yano, M. et al. Aberrant promoter methylation of human DAB2 interactive protein (hDAB2IP) gene in lung cancers. Int. J. Cancer 113, 59-66 (2005).
-
(2005)
Int. J. Cancer
, vol.113
, pp. 59-66
-
-
Yano, M.1
-
25
-
-
42049105550
-
AIP1 recruits phosphatase PP2A to ASK1 in tumor necrosis factor-induced ASK1-JNK activation
-
Min, W. et al. AIP1 recruits phosphatase PP2A to ASK1 in tumor necrosis factor-induced ASK1-JNK activation. Circulation Research 102, 840-848 (2008).
-
(2008)
Circulation Research
, vol.102
, pp. 840-848
-
-
Min, W.1
-
27
-
-
7244253045
-
AIP1/DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation
-
Zhang, H. F. et al. AIP1/DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation. Journal of Biological Chemistry 279, 44955-44965 (2004).
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 44955-44965
-
-
Zhang, H.F.1
-
28
-
-
77249104533
-
Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis
-
Xie, D. X. et al. Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis. Proceedings of the National Academy of Sciences of the United States of America 107, 2485-2490 (2010).
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, pp. 2485-2490
-
-
Xie, D.X.1
-
29
-
-
77749297990
-
An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappa B
-
Min, J. et al. An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappa B. Nat. Med. 16, 286-U282 (2010).
-
(2010)
Nat. Med.
, vol.16
, pp. 286-U282
-
-
Min, J.1
-
30
-
-
77950494286
-
Molecular basis of colorectal cancer
-
author reply 1246-1247
-
Batistatou, A., Charalabopoulos, A. & Charalabopoulos, K. Molecular basis of colorectal cancer. N Engl J Med 362, 1246 author reply 1246-1247 (2010).
-
(2010)
N Engl J Med
, vol.362
, pp. 1246
-
-
Batistatou, A.1
Charalabopoulos, A.2
Charalabopoulos, K.3
-
31
-
-
0034282097
-
Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover
-
Henderson, B. R. Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover. Nat Cell Biol 2, 653-660 (2000).
-
(2000)
Nat Cell Biol
, vol.2
, pp. 653-660
-
-
Henderson, B.R.1
-
32
-
-
0037416148
-
Nuclear export of the APC tumour suppressor controls beta-catenin function in transcription
-
Rosin-Arbesfeld, R., Cliffe, A., Brabletz, T. & Bienz, M. Nuclear export of the APC tumour suppressor controls beta-catenin function in transcription. EMBO J 22, 1101-1113 (2003).
-
(2003)
EMBO J
, vol.22
, pp. 1101-1113
-
-
Rosin-Arbesfeld, R.1
Cliffe, A.2
Brabletz, T.3
Bienz, M.4
-
33
-
-
33745809820
-
Adenomatous polyposis coli (APC) differentially regulates beta-catenin phosphorylation and ubiquitination in colon cancer cells
-
Yang, J. et al. Adenomatous polyposis coli (APC) differentially regulates beta-catenin phosphorylation and ubiquitination in colon cancer cells. J Biol Chem 281, 17751-17757 (2006).
-
(2006)
J Biol Chem
, vol.281
, pp. 17751-17757
-
-
Yang, J.1
-
34
-
-
0034724186
-
APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits"
-
Rowan, A. J. et al. APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits". Proc Natl Acad Sci USA 97, 3352-3357 (2000).
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3352-3357
-
-
Rowan, A.J.1
-
35
-
-
77249104533
-
Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis
-
Xie, D. et al. Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis. Proc Natl Acad Sci USA 107, 2485-2490 (2010).
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 2485-2490
-
-
Xie, D.1
-
36
-
-
0032521433
-
Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer
-
Sparks, A. B., Morin, P. J., Vogelstein, B. & Kinzler, K. W. Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer. Cancer Res 58, 1130-1134 (1998).
-
(1998)
Cancer Res
, vol.58
, pp. 1130-1134
-
-
Sparks, A.B.1
Morin, P.J.2
Vogelstein, B.3
Kinzler, K.W.4
-
37
-
-
0036781052
-
NF-kappaB regulation in the immune system
-
Li, Q. & Verma, I. M. NF-kappaB regulation in the immune system. Nat Rev Immunol 2, 725-734 (2002).
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 725-734
-
-
Li, Q.1
Verma, I.M.2
-
38
-
-
67650724069
-
Regulation and function of NF-kappaB transcription factors in the immune system
-
Vallabhapurapu, S. & Karin, M. Regulation and function of NF-kappaB transcription factors in the immune system. Annu Rev Immunol 27, 693-733 (2009).
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 693-733
-
-
Vallabhapurapu, S.1
Karin, M.2
-
39
-
-
41649104112
-
Activated NF-kB in colorectal cancer: Predictive or prognostic factor?
-
author reply 1389-1390
-
Brandi, G., Pantaleo, M. A., Biasco, G. & Paterini, P. Activated NF-kB in colorectal cancer: predictive or prognostic factor? J Clin Oncol 26, 1388-1389 author reply 1389-1390 (2008).
-
(2008)
J Clin Oncol
, vol.26
, pp. 1388-1389
-
-
Brandi, G.1
Pantaleo, M.A.2
Biasco, G.3
Paterini, P.4
-
40
-
-
65249141108
-
Constitutive NF-kappaB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth
-
Sakamoto, K. et al. Constitutive NF-kappaB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth. Clin Cancer Res 15, 2248-2258 (2009).
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2248-2258
-
-
Sakamoto, K.1
-
41
-
-
34548536941
-
Nuclear factor-kB tumor expression predicts response and survival in irinotecan-refractory metastatic colorectal cancer treated with cetuximab-irinotecan therapy
-
Scartozzi, M. et al. Nuclear factor-kB tumor expression predicts response and survival in irinotecan-refractory metastatic colorectal cancer treated with cetuximab-irinotecan therapy. J Clin Oncol 25, 3930-3935 (2007).
-
(2007)
J Clin Oncol
, vol.25
, pp. 3930-3935
-
-
Scartozzi, M.1
-
42
-
-
0036546501
-
NF-kappaB in cancer: From innocent bystander to major culprit
-
Karin, M., Cao, Y., Greten, F. R. & Li, Z. W. NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2, 301-310 (2002).
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 301-310
-
-
Karin, M.1
Cao, Y.2
Greten, F.R.3
Li, Z.W.4
-
43
-
-
76949084622
-
TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion
-
Wu, Y. & Zhou, B. P. TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion. Br J Cancer 102, 639-644 (2010).
-
(2010)
Br J Cancer
, vol.102
, pp. 639-644
-
-
Wu, Y.1
Zhou, B.P.2
-
44
-
-
84863280130
-
Epithelial-mesenchymal transition induced by TNF-alpha requires NF-kappaB-mediated transcriptional upregulation of Twist1
-
Li, C. W. et al. Epithelial-mesenchymal transition induced by TNF-alpha requires NF-kappaB-mediated transcriptional upregulation of Twist1. Cancer Res 72, 1290-1300 (2012).
-
(2012)
Cancer Res
, vol.72
, pp. 1290-1300
-
-
Li, C.W.1
-
45
-
-
33846828787
-
NF-kappaB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: Potential involvement of ZEB-1 and ZEB-2
-
Chua, H. L. et al. NF-kappaB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: potential involvement of ZEB-1 and ZEB-2. Oncogene 26, 711-724 (2007).
-
(2007)
Oncogene
, vol.26
, pp. 711-724
-
-
Chua, H.L.1
-
46
-
-
0036707512
-
Nuclear factor kappaB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity
-
Hinz, M. et al. Nuclear factor kappaB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity. J Exp Med 196, 605-617 (2002).
-
(2002)
J Exp Med
, vol.196
, pp. 605-617
-
-
Hinz, M.1
-
47
-
-
84872600554
-
Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties
-
Schwitalla, S. et al. Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties. Cell 152, 25-38 (2013).
-
(2013)
Cell
, vol.152
, pp. 25-38
-
-
Schwitalla, S.1
-
48
-
-
0036781671
-
Beta-catenin interacts with and inhibits NF-kappa B in human colon and breast cancer
-
Deng, J. et al. beta-catenin interacts with and inhibits NF-kappa B in human colon and breast cancer. Cancer Cell 2, 323-334 (2002).
-
(2002)
Cancer Cell
, vol.2
, pp. 323-334
-
-
Deng, J.1
-
49
-
-
42949087894
-
Isolation and culture of colon cancer stem cells
-
Cammareri, P. et al. Isolation and culture of colon cancer stem cells. Methods Cell Biol 86, 311-324 (2008).
-
(2008)
Methods Cell Biol
, vol.86
, pp. 311-324
-
-
Cammareri, P.1
|