The cancer cell oxygen sensor PHD2 promotes metastasis via activation of cancer-associated fibroblasts

Cell Reports

Volumn 12, Issue 6, 2015, Pages 992-1005

  Kuchnio, Anna ^a,b   Moens, Stijn ^a,b   Bruning, Ulrike ^a,b   Kuchnio, Karol ^a,b   Cruys, Bert ^a,b   Thienpont, Bernard ^b,c   Broux, Michaël ^a,b   Ungureanu, Andreea Alexandra ^a   de Oliveira, Rodrigo Leite ^a,b   Bruyère, Françoise ^a,b   Cuervo, Henar ^a,b   Manderveld, Ann ^a,b   Carton, An ^a,b   Hernandez Fernaud, Juan Ramon ^d   Zanivan, Sara ^d   Bartic, Carmen ^a,e   Foidart, Jean Michel ^f   Noel, Agnes ^f   Vinckier, Stefan ^a,b   Lambrechts, Diether ^b,c   Dewerchin, Mieke ^a,b   Mazzone, Massimiliano ^a,b   Carmeliet, Peter ^a,b   more..

^a UNIVERSITY OF LEUVEN   (Belgium)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^e IMEC   (Belgium)

^f UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROLYL HYDROXYLASE 2; UNCLASSIFIED DRUG; EGLN1 PROTEIN, MOUSE; HYPOXIA INDUCIBLE FACTOR PROLINE DIOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CELL ACTIVATION; CELL INVASION; CONTROLLED STUDY; ENZYME INHIBITION; FEMALE; FIBROBLAST; HAPLOINSUFFICIENCY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; LUNG METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STROMA CELL; TUMOR GROWTH; TUMOR VOLUME; ANIMAL; BIOLOGICAL MODEL; GENETICS; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; METASTASIS; NEOPLASM; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; FEMALE; FIBROBLASTS; HUMANS; HYPOXIA-INDUCIBLE FACTOR-PROLINE DIOXYGENASES; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; MICE; MODELS, BIOLOGICAL; NEOPLASM METASTASIS; NEOPLASMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84946868067     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.07.010     Document Type: Article

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