Selective small molecule probes for the hypoxia inducible factor (HIF) Prolyl Hydroxylases

ACS Chemical Biology

Volumn 8, Issue 7, 2013, Pages 1488-1496

  Chowdhury, Rasheduzzaman ^a   Candela Lena, José Ignacio ^a,b   Chan, Mun Chiang ^a   Greenald, David Jeremy ^c,d   Yeoh, Kar Kheng ^a   Tian, Ya Min ^e   McDonough, Michael A ^a   Tumber, Anthony ^f   Rose, Nathan R ^a   Conejo Garcia, Ana ^a   Demetriades, Marina ^a   Mathavan, Sinnakaruppan ^c   Kawamura, Akane ^a   Lee, Myung Kyu ^g   Van Eeden, Freek ^d   Pugh, Christopher W ^e   Ratcliffe, Peter J ^e   Schofield, Christopher J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF SEVILLE   (Spain)

^c GENOME INSTITUTE OF SINGAPORE   (Singapore)

^d UNIVERSITY OF SHEFFIELD   (United Kingdom)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f UNIVERSITY OF OXFORD   (United Kingdom)

^g Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOGLUTARIC ACID; FERROUS ION; HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; OXYGEN; OXYGENASE; OXYGENASE INHIBITOR; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL LEVEL; CONTROLLED STUDY; CRYSTALLOGRAPHY; EMBRYO; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME STRUCTURE; HUMAN; HUMAN CELL; MOLECULAR IMAGING; MOLECULE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ZEBRA FISH;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANOXIA; BIOLOGICAL ASSAY; CELL LINE; HETEROCYCLIC COMPOUNDS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; HYPOXIA-INDUCIBLE FACTOR-PROLINE DIOXYGENASES; INHIBITORY CONCENTRATION 50; MODELS, MOLECULAR; MOLECULAR STRUCTURE; SIGNAL TRANSDUCTION; SMALL MOLECULE LIBRARIES; ZEBRAFISH;

EID: 84880534866     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb400088q     Document Type: Article

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