APOBEC-Induced Cancer Mutations Are Uniquely Enriched in Early-Replicating, Gene-Dense, and Active Chromatin Regions

Cell Reports

Volumn 13, Issue 6, 2015, Pages 1103-1109

  Kazanov, Marat D ^a   Roberts, Steven A ^b,c   Polak, Paz ^d   Stamatoyannopoulos, John ^e   Klimczak, Leszek J ^b   Gordenin, Dmitry A ^b   Sunyaev, Shamil R ^d  

^a INSTITUTE FOR INFORMATION TRANSMISSION PROBLEMS   (Russian Federation)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c WASHINGTON STATE UNIVERSITY   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SINGLE STRANDED DNA; CYTIDINE DEAMINASE; EUCHROMATIN;

APOBEC GENE; ARTICLE; BREAST CANCER; CANCER GENOME; CARCINOGENESIS; CHROMATIN; CONTROLLED STUDY; DNA REPLICATION; EPIGENETICS; EUCHROMATIN; GENE CLUSTER; GENE LOCATION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; LUNG CANCER; MUTAGENESIS; MUTATIONAL ANALYSIS; ONCOGENE; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; BREAST TUMOR; FEMALE; GENETICS; HUMAN; LUNG TUMOR; MCF-7 CELL LINE; MUTATION; MUTATION RATE;

BREAST NEOPLASMS; CYTIDINE DEAMINASE; DNA REPLICATION; EUCHROMATIN; FEMALE; HUMANS; LUNG NEOPLASMS; MCF-7 CELLS; MUTATION; MUTATION RATE;

EID: 84946838553     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.09.077     Document Type: Article

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