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Volumn 54, Issue 11, 2015, Pages 2085-2094

Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission

Author keywords

ANCA; ANCA associated vasculitis; NET remnants; Neutrophil extracellular trap (NET); Small vessel vasculitis

Indexed keywords

NEUTROPHIL CYTOPLASMIC ANTIBODY; PREDNISOLONE;

EID: 84946712446     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/kev217     Document Type: Article
Times cited : (96)

References (43)
  • 1
  • 2
    • 67349279881 scopus 로고    scopus 로고
    • Netting neutrophils in autoimmune small-vessel vasculitis
    • Kessenbrock K, Krumbholz M, Schonermarck U et al. Netting neutrophils in autoimmune small-vessel vasculitis. Nat Med 2009;15:623-5.
    • (2009) Nat Med , vol.15 , pp. 623-625
    • Kessenbrock, K.1    Krumbholz, M.2    Schonermarck, U.3
  • 3
    • 1542287347 scopus 로고    scopus 로고
    • Neutrophil extracellular traps kill bacteria
    • Brinkmann V, Reichard U, Goosmann C et al. Neutrophil extracellular traps kill bacteria. Science 2004;303:1532-5.
    • (2004) Science , vol.303 , pp. 1532-1535
    • Brinkmann, V.1    Reichard, U.2    Goosmann, C.3
  • 4
    • 73649099522 scopus 로고    scopus 로고
    • Neutrophil extracellular traps contain calprotectin, a cytosolic protein complex involved in host defense against Candida albicans
    • Urban CF, Ermert D, Schmid M et al. Neutrophil extracellular traps contain calprotectin, a cytosolic protein complex involved in host defense against Candida albicans. PLoS Pathog 2009;5:e1000639.
    • (2009) PLoS Pathog , vol.5
    • Urban, C.F.1    Ermert, D.2    Schmid, M.3
  • 5
    • 79952476762 scopus 로고    scopus 로고
    • Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus
    • Garcia-Romo GS, Caielli S, Vega B et al. Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus. Sci Transl Med 2011;3:73ra20.
    • (2011) Sci Transl Med , vol.3
    • Garcia-Romo, G.S.1    Caielli, S.2    Vega, B.3
  • 6
    • 84857591047 scopus 로고    scopus 로고
    • Neutrophil extracellular traps directly induce epithelial and endothelial cell death: a predominant role of histones
    • Saffarzadeh M, Juenemann C, Queisser MA et al. Neutrophil extracellular traps directly induce epithelial and endothelial cell death: a predominant role of histones. PLoS One 2012;7:e32366.
    • (2012) PLoS One , vol.7
    • Saffarzadeh, M.1    Juenemann, C.2    Queisser, M.A.3
  • 7
    • 79960392810 scopus 로고    scopus 로고
    • Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus
    • Villanueva E, Yalavarthi S, Berthier CC et al. Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus. J Immunol 2011;187:538-52.
    • (2011) J Immunol , vol.187 , pp. 538-552
    • Villanueva, E.1    Yalavarthi, S.2    Berthier, C.C.3
  • 8
    • 77954176096 scopus 로고    scopus 로고
    • Activated endothelial cells induce neutrophil extracellular traps and are susceptible to NETosis-mediated cell death
    • Gupta AK, Joshi MB, Philippova M et al. Activated endothelial cells induce neutrophil extracellular traps and are susceptible to NETosis-mediated cell death. FEBS Lett 2010;584:3193-7.
    • (2010) FEBS Lett , vol.584 , pp. 3193-3197
    • Gupta, A.K.1    Joshi, M.B.2    Philippova, M.3
  • 9
    • 84867836102 scopus 로고    scopus 로고
    • Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity
    • Sangaletti S, Tripodo C, Chiodoni C et al. Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity. Blood 2012;120:3007-18.
    • (2012) Blood , vol.120 , pp. 3007-3018
    • Sangaletti, S.1    Tripodo, C.2    Chiodoni, C.3
  • 10
    • 33846432787 scopus 로고    scopus 로고
    • Novel cell death program leads to neutrophil extracellular traps
    • Fuchs TA, Abed U, Goosmann C et al. Novel cell death program leads to neutrophil extracellular traps. J Cell Biol 2007;176:231-41.
    • (2007) J Cell Biol , vol.176 , pp. 231-241
    • Fuchs, T.A.1    Abed, U.2    Goosmann, C.3
  • 11
    • 32944463724 scopus 로고    scopus 로고
    • Neutrophil extracellular traps capture and kill Candida albicans yeast and hyphal forms
    • Urban CF, Reichard U, Brinkmann V, Zychlinsky A. Neutrophil extracellular traps capture and kill Candida albicans yeast and hyphal forms. Cell Microbiol 2006;8:668-76.
    • (2006) Cell Microbiol , vol.8 , pp. 668-676
    • Urban, C.F.1    Reichard, U.2    Brinkmann, V.3    Zychlinsky, A.4
  • 12
    • 66149134072 scopus 로고    scopus 로고
    • Leishmania amazonensis promastigotes induce and are killed by neutrophil extracellular traps
    • Guimaraes-Costa AB, Nascimento MT, Froment GS et al. Leishmania amazonensis promastigotes induce and are killed by neutrophil extracellular traps. Proc Natl Acad Sci USA 2009;106:6748-53.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 6748-6753
    • Guimaraes-Costa, A.B.1    Nascimento, M.T.2    Froment, G.S.3
  • 13
    • 34147188469 scopus 로고    scopus 로고
    • Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood
    • Clark SR, Ma AC, Tavener SA et al. Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood. Nat Med 2007;13:463-9.
    • (2007) Nat Med , vol.13 , pp. 463-469
    • Clark, S.R.1    Ma, A.C.2    Tavener, S.A.3
  • 14
    • 84868632379 scopus 로고    scopus 로고
    • Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo
    • Yipp BG, Petri B, Salina D et al. Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo. Nat Med 2012;18:1386-93.
    • (2012) Nat Med , vol.18 , pp. 1386-1393
    • Yipp, B.G.1    Petri, B.2    Salina, D.3
  • 15
    • 84893111758 scopus 로고    scopus 로고
    • Degradation of neutrophil extracellular traps co-varies with disease activity in patients with systemic lupus erythematosus
    • Leffler J, Gullstrand B, Jonsen A et al. Degradation of neutrophil extracellular traps co-varies with disease activity in patients with systemic lupus erythematosus. Arthritis Res Ther 2013;15:R84.
    • (2013) Arthritis Res Ther , vol.15
    • Leffler, J.1    Gullstrand, B.2    Jonsen, A.3
  • 16
    • 84876104421 scopus 로고    scopus 로고
    • NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis
    • Khandpur R, Carmona-Rivera C, Vivekanandan-Giri A et al. NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis. Sci Transl Med 2013;5:178ra40.
    • (2013) Sci Transl Med , vol.5
    • Khandpur, R.1    Carmona-Rivera, C.2    Vivekanandan-Giri, A.3
  • 17
    • 33645234855 scopus 로고    scopus 로고
    • Induction of neutrophil extracellular DNA lattices by placental microparticles and IL-8 and their presence in preeclampsia
    • Gupta AK, Hasler P, Holzgreve W, Gebhardt S, Hahn S. Induction of neutrophil extracellular DNA lattices by placental microparticles and IL-8 and their presence in preeclampsia. Hum Immunol 2005;66:1146-54.
    • (2005) Hum Immunol , vol.66 , pp. 1146-1154
    • Gupta, A.K.1    Hasler, P.2    Holzgreve, W.3    Gebhardt, S.4    Hahn, S.5
  • 18
    • 84861227655 scopus 로고    scopus 로고
    • Felty's syndrome autoantibodies bind to deiminated histones and neutrophil extracellular chromatin traps
    • Dwivedi N, Upadhyay J, Neeli I et al. Felty's syndrome autoantibodies bind to deiminated histones and neutrophil extracellular chromatin traps. Arthritis Rheum 2012;64:982-92.
    • (2012) Arthritis Rheum , vol.64 , pp. 982-992
    • Dwivedi, N.1    Upadhyay, J.2    Neeli, I.3
  • 19
    • 84902057700 scopus 로고    scopus 로고
    • Enhanced neutrophil extracellular trap generation in rheumatoid arthritis: analysis of underlying signal transduction pathways and potential diagnostic utility
    • Sur Chowdhury C, Giaglis S, Walker UA et al. Enhanced neutrophil extracellular trap generation in rheumatoid arthritis: analysis of underlying signal transduction pathways and potential diagnostic utility. Arthritis Res Ther 2014;16:R122.
    • (2014) Arthritis Res Ther , vol.16
    • Sur Chowdhury, C.1    Giaglis, S.2    Walker, U.A.3
  • 20
    • 84868114208 scopus 로고    scopus 로고
    • Abnormal conformation and impaired degradation of propylthiouracilinduced neutrophil extracellular traps: implications of disordered neutrophil extracellular traps in a rat model of myeloperoxidase antineutrophil cytoplasmic antibodyassociated vasculitis
    • Nakazawa D, Tomaru U, Suzuki A, et al. Abnormal conformation and impaired degradation of propylthiouracilinduced neutrophil extracellular traps: implications of disordered neutrophil extracellular traps in a rat model of myeloperoxidase antineutrophil cytoplasmic antibodyassociated vasculitis. Arthritis Rheum 2012;64:3779-87.
    • (2012) Arthritis Rheum , vol.64 , pp. 3779-3787
    • Nakazawa, D.1    Tomaru, U.2    Suzuki, A.3
  • 21
    • 0033529565 scopus 로고    scopus 로고
    • Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosome
    • Kornberg RD, Lorch Y. Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosome. Cell 1999;98:285-94.
    • (1999) Cell , vol.98 , pp. 285-294
    • Kornberg, R.D.1    Lorch, Y.2
  • 22
    • 80053914458 scopus 로고    scopus 로고
    • Fractionation of granulocytes from whole human blood by centrifugation. Practical hints
    • Munteanu LS, Dinu A. Fractionation of granulocytes from whole human blood by centrifugation. Practical hints. Romanian J Biophys 2004;14:53-8.
    • (2004) Romanian J Biophys , vol.14 , pp. 53-58
    • Munteanu, L.S.1    Dinu, A.2
  • 23
    • 84882271011 scopus 로고    scopus 로고
    • Leukocyte and serum S100A8/S100A9 expression reflects disease activity in ANCA-associated vasculitis and glomerulonephritis
    • Pepper RJ, Hamour S, Chavele KM et al. Leukocyte and serum S100A8/S100A9 expression reflects disease activity in ANCA-associated vasculitis and glomerulonephritis. Kidney Int 2013;83:1150-8.
    • (2013) Kidney Int , vol.83 , pp. 1150-1158
    • Pepper, R.J.1    Hamour, S.2    Chavele, K.M.3
  • 24
    • 77953088427 scopus 로고    scopus 로고
    • Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis
    • Hakkim A, Furnrohr BG, Amann K et al. Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis. Proc Natl Acad Sci USA 2010;107:9813-8.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 9813-9818
    • Hakkim, A.1    Furnrohr, B.G.2    Amann, K.3
  • 25
    • 0030894460 scopus 로고    scopus 로고
    • Binding and inhibition of myeloperoxidase (MPO): a major function of ceruloplasmin?
    • Segelmark M, Persson B, Hellmark T, Wieslander J. Binding and inhibition of myeloperoxidase (MPO): a major function of ceruloplasmin? Clin Exp Immunol 1997;108:167-74
    • (1997) Clin Exp Immunol , vol.108 , pp. 167-174
    • Segelmark, M.1    Persson, B.2    Hellmark, T.3    Wieslander, J.4
  • 26
    • 84875827100 scopus 로고    scopus 로고
    • Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis
    • Roth AJ, Ooi JD, Hess JJ et al. Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis. J Clin Invest 2013;123:1773-83.
    • (2013) J Clin Invest , vol.123 , pp. 1773-1783
    • Roth, A.J.1    Ooi, J.D.2    Hess, J.J.3
  • 27
    • 79651473201 scopus 로고    scopus 로고
    • Neutrophil extracellular trap cell death requires both autophagy and superoxide generation
    • Remijsen Q, Vanden Berghe T, Wirawan E et al. Neutrophil extracellular trap cell death requires both autophagy and superoxide generation. Cell Res 2011;21:290-304.
    • (2011) Cell Res , vol.21 , pp. 290-304
    • Remijsen, Q.1    Vanden Berghe, T.2    Wirawan, E.3
  • 28
    • 84905507197 scopus 로고    scopus 로고
    • Pathogenesis of antineutrophil cytoplasmic autoantibody-mediated disease
    • Jennette JC, Falk RJ. Pathogenesis of antineutrophil cytoplasmic autoantibody-mediated disease. Nat Rev Rheumatol 2014;10:463-73.
    • (2014) Nat Rev Rheumatol , vol.10 , pp. 463-473
    • Jennette, J.C.1    Falk, R.J.2
  • 29
    • 77952196152 scopus 로고    scopus 로고
    • Epitope shift of proteinase-3 anti-neutrophil cytoplasmic antibodies in patients with small vessel vasculitis
    • Selga D, Segelmark M, Gunnarsson L, Hellmark T. Epitope shift of proteinase-3 anti-neutrophil cytoplasmic antibodies in patients with small vessel vasculitis. Clin Exp Immunol 2010;160:318-24.
    • (2010) Clin Exp Immunol , vol.160 , pp. 318-324
    • Selga, D.1    Segelmark, M.2    Gunnarsson, L.3    Hellmark, T.4
  • 30
    • 0842287491 scopus 로고    scopus 로고
    • Diversity of PR3-ANCA epitope specificity in Wegener's granulomatosis. Analysis using the biosensor technology
    • Rarok AA, van der Geld YM, Stegeman CA, Limburg PC, Kallenberg CG. Diversity of PR3-ANCA epitope specificity in Wegener's granulomatosis. Analysis using the biosensor technology. J Clin Immunol 2003;23:460-8.
    • (2003) J Clin Immunol , vol.23 , pp. 460-468
    • Rarok, A.A.1    van der Geld, Y.M.2    Stegeman, C.A.3    Limburg, P.C.4    Kallenberg, C.G.5
  • 31
    • 0345700717 scopus 로고    scopus 로고
    • Increased circulating levels of proteinase 3 in patients with antineutrophilic cytoplasmic autoantibodies-associated systemic vasculitis in remission
    • Ohlsson S, Wieslander J, Segelmark M. Increased circulating levels of proteinase 3 in patients with antineutrophilic cytoplasmic autoantibodies-associated systemic vasculitis in remission. Clin Exp Immunol 2003;131:528-35.
    • (2003) Clin Exp Immunol , vol.131 , pp. 528-535
    • Ohlsson, S.1    Wieslander, J.2    Segelmark, M.3
  • 32
    • 77956230395 scopus 로고    scopus 로고
    • Natural autoantibodies to myeloperoxidase, proteinase 3, and the glomerular basement membrane are present in normal individuals
    • Cui Z, Zhao MH, Segelmark M, Hellmark T. Natural autoantibodies to myeloperoxidase, proteinase 3, and the glomerular basement membrane are present in normal individuals. Kidney Int 2010;78:590-7.
    • (2010) Kidney Int , vol.78 , pp. 590-597
    • Cui, Z.1    Zhao, M.H.2    Segelmark, M.3    Hellmark, T.4
  • 33
    • 84919624844 scopus 로고    scopus 로고
    • Natural antibodies bridge innate and adaptive immunity
    • Panda S, Ding JL. Natural antibodies bridge innate and adaptive immunity. J Immunol 2015;194:13-20.
    • (2015) J Immunol , vol.194 , pp. 13-20
    • Panda, S.1    Ding, J.L.2
  • 34
    • 84875638187 scopus 로고    scopus 로고
    • Natural IgG autoantibodies are abundant and ubiquitous in human sera, and their number is influenced by age, gender, and disease
    • Nagele EP, Han M, Acharya NK et al. Natural IgG autoantibodies are abundant and ubiquitous in human sera, and their number is influenced by age, gender, and disease. PLoS One 2013;8:e60726.
    • (2013) PLoS One , vol.8
    • Nagele, E.P.1    Han, M.2    Acharya, N.K.3
  • 35
    • 84931325381 scopus 로고    scopus 로고
    • Neutrophil extracellular Trap-related extracellular histones cause vascular necrosis in severe GN
    • Feb 2. pii: JASN.2014070673. [Epub ahead of print]
    • Kumar SV, Kulkarni OP, Mulay SR et al. Neutrophil extracellular Trap-related extracellular histones cause vascular necrosis in severe GN. J Am Soc Nephrol 2015 Feb 2. pii: JASN.2014070673. [Epub ahead of print].
    • (2015) J Am Soc Nephrol
    • Kumar, S.V.1    Kulkarni, O.P.2    Mulay, S.R.3
  • 36
    • 84857753305 scopus 로고    scopus 로고
    • Decreased neutrophil apoptosis in quiescent ANCAassociated systemic vasculitis
    • Abdgawad M, Pettersson A, Gunnarsson L et al. Decreased neutrophil apoptosis in quiescent ANCAassociated systemic vasculitis. PLoS One 2012;7:e32439.
    • (2012) PLoS One , vol.7
    • Abdgawad, M.1    Pettersson, A.2    Gunnarsson, L.3
  • 37
    • 9644270174 scopus 로고    scopus 로고
    • Circulating cytokine profile in anti-neutrophilic cytoplasmatic autoantibody-associated vasculitis: prediction of outcome?
    • Ohlsson S, Wieslander J, Segelmark M. Circulating cytokine profile in anti-neutrophilic cytoplasmatic autoantibody-associated vasculitis: prediction of outcome? Mediators Inflamm 2004;13:275-83.
    • (2004) Mediators Inflamm , vol.13 , pp. 275-283
    • Ohlsson, S.1    Wieslander, J.2    Segelmark, M.3
  • 38
    • 67650073210 scopus 로고    scopus 로고
    • Intracellular cytokine production in ANCA-associated vasculitis: low levels of interleukin-10 in remission are associated with a higher relapse rate in the long-term follow-up
    • Hruskova Z, Rihova Z, Mareckova H et al. Intracellular cytokine production in ANCA-associated vasculitis: low levels of interleukin-10 in remission are associated with a higher relapse rate in the long-term follow-up. Arch Med Res 2009;40:276-84.
    • (2009) Arch Med Res , vol.40 , pp. 276-284
    • Hruskova, Z.1    Rihova, Z.2    Mareckova, H.3
  • 39
    • 77952975740 scopus 로고    scopus 로고
    • Serum IL-17 and IL-23 levels and autoantigen-specific Th17 cells are elevated in patients with ANCA-associated vasculitis
    • Nogueira E, Hamour S, Sawant D et al. Serum IL-17 and IL-23 levels and autoantigen-specific Th17 cells are elevated in patients with ANCA-associated vasculitis. Nephrol Dial Transplant 2010;25:2209-17.
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 2209-2217
    • Nogueira, E.1    Hamour, S.2    Sawant, D.3
  • 40
    • 84868113151 scopus 로고    scopus 로고
    • Cytokines induced neutrophil extracellular traps formation: implication for the inflammatory disease condition
    • Keshari RS, Jyoti A, Dubey M et al. Cytokines induced neutrophil extracellular traps formation: implication for the inflammatory disease condition. PLoS One 2012;7:e48111.
    • (2012) PLoS One , vol.7
    • Keshari, R.S.1    Jyoti, A.2    Dubey, M.3
  • 41
    • 0029057979 scopus 로고
    • Glucocorticoid treatment inhibits apoptosis in human neutrophils. Separation of survival and activation outcomes
    • Cox G. Glucocorticoid treatment inhibits apoptosis in human neutrophils. Separation of survival and activation outcomes. J Immunol 1995;154:4719-25.
    • (1995) J Immunol , vol.154 , pp. 4719-4725
    • Cox, G.1
  • 42
    • 84891606010 scopus 로고    scopus 로고
    • A myelopoiesis gene signature during remission in anti-neutrophil cytoplasm antibody-associated vasculitis does not predict relapses but seems to reflect ongoing prednisolone therapy
    • Kurz T, Weiner M, Skoglund C et al. A myelopoiesis gene signature during remission in anti-neutrophil cytoplasm antibody-associated vasculitis does not predict relapses but seems to reflect ongoing prednisolone therapy. Clin Exp Immunol 2014;175:215-26.
    • (2014) Clin Exp Immunol , vol.175 , pp. 215-226
    • Kurz, T.1    Weiner, M.2    Skoglund, C.3
  • 43
    • 84903134145 scopus 로고    scopus 로고
    • Low production of reactive oxygen species in granulocytes is associated with organ damage in systemic lupus erythematosus
    • Bengtsson AA, Pettersson A, Wichert S et al. Low production of reactive oxygen species in granulocytes is associated with organ damage in systemic lupus erythematosus. Arthritis Res Ther 2014;16:R120.
    • (2014) Arthritis Res Ther , vol.16
    • Bengtsson, A.A.1    Pettersson, A.2    Wichert, S.3


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