Curcumin retunes cholesterol transport homeostasis and inflammation response in M1 macrophage to prevent atherosclerosis

Biochemical and Biophysical Research Communications

Volumn 467, Issue 4, 2015, Pages 872-878

  Chen, Fang Yuan ^a   Zhou, Juan ^a   Guo, Ning ^a   Ma, Wang Ge ^a   Huang, Xin ^a   Wang, Huan ^a   Yuan, Zu Yi ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

Cholesterol efflux; Cholesterol uptake; Curcumin; Inflammation; M1 macrophages; PPAR

Indexed keywords

ABC TRANSPORTER A1; APOLIPOPROTEIN A1; CD36 ANTIGEN; CURCUMIN; GAMMA INTERFERON; HIGH DENSITY LIPOPROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; OXIDIZED LOW DENSITY LIPOPROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TUMOR NECROSIS FACTOR ALPHA; ABCA1 PROTEIN, MOUSE; CHOLESTEROL;

ANIMAL CELL; APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; BINDING ASSAY; CHOLESTEROL ESTERIFICATION; CHOLESTEROL TRANSPORT; CYTOKINE PRODUCTION; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG METABOLISM; FOAM CELL; HUMAN; INFLAMMATION; LIPID STORAGE; MACROPHAGE; METABOLIC SYNDROME X; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINGLE DRUG DOSE; UPREGULATION; ANIMAL; CELL LINE; DRUG EFFECTS; ESTERIFICATION; HOMEOSTASIS; METABOLISM; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; ANTIGENS, CD36; ATHEROSCLEROSIS; ATP BINDING CASSETTE TRANSPORTER 1; BIOLOGICAL TRANSPORT; CELL LINE; CHOLESTEROL; CURCUMIN; ESTERIFICATION; HOMEOSTASIS; INFLAMMATION; MACROPHAGES; MICE; PPAR GAMMA;

EID: 84946551735     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.10.051     Document Type: Article

References (33)

1. S.K. Shin, T.Y. Ha, R.A. McGregor, and et al. Long-term curcumin administration protects against atherosclerosis via hepatic regulation of lipoprotein cholesterol metabolism Mol. Nutr. Food Res. 55 2011 1829 1840
2. R. Ross Atherosclerosis- an inflammatory disease N. Engl. J. Med. 340 1999 115 126
3. M.F. Linton, and S. Fazio Macrophages, inflammation, and atherosclerosis Int. J. Obes. Relat. Metab. Disord. 27 Suppl. 3 2003 S35 S40
4. Y.M. Park CD36, a scavenger receptor implicated in atherosclerosis Exp. Mol. Med. 46 2014 e99
5. X.H. Yu, Y.C. Fu, D.W. Zhang, and et al. Foam cells in atherosclerosis Clin. Chim. Acta 424 2013 245 252
6. S.H. Park, J.L. Kim, E.S. Lee, and et al. Dietary ellagic acid attenuates oxidized LDL uptake and stimulates cholesterol efflux in murine macrophages J. Nutr. 141 2011 1931 1937
7. S.K. Biswas, M. Chittezhath, I.N. Shalova, and et al. Macrophage polarization and plasticity in health and disease Immunol. Res. 53 2012 11 24
8. H.J. Medbury, H. Williams, and J.P. Fletcher Clinical significance of macrophage phenotypes in cardiovascular disease Clin. Transl. Med. 3 2014 63
9. S.H. Shin, C.L. Stout, A.I. Richardson, and et al. Carotid angioplasty and stenting in anatomically high-risk patients: safe and durable except for radiation-induced stenosis J. Vasc. Surg. 50 2009 762 767
10. M.A. Bouhlel, B. Derudas, E. Rigamonti, and et al. PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties Cell Metab. 6 2007 137 143
11. I.M. Wolfs, M.M. Donners, and M.P. de Winther Differentiation factors and cytokines in the atherosclerotic plaque micro-environment as a trigger for macrophage polarisation Thromb. Haemost. 106 2011 763 771
12. J. Oh, A.E. Riek, S. Weng, and et al. Endoplasmic reticulum stress controls M2 macrophage differentiation and foam cell formation J. Biol. Chem. 287 2012 11629 11641
13. J. Persson, J. Nilsson, and M.W. Lindholm Interleukin-1beta and tumour necrosis factor-alpha impede neutral lipid turnover in macrophage-derived foam cells BMC Immunol. 9 2008 70
14. J.M. Zingg, S.T. Hasan, and M. Meydani Molecular mechanisms of hypolipidemic effects of curcumin Biofactors 39 2013 101 121
15. W. Wongcharoen, and A. Phrommintikul The protective role of curcumin in cardiovascular diseases Int. J. Cardiol. 133 2009 145 151
16. J. Li, G. Cui, L. Sun, and et al. ARHI overexpression induces epithelial ovarian cancer cell apoptosis and excessive autophagy Int. J. Gynecol. Cancer 24 2014 437 443
17. S.W. Sun, X.Y. Zu, Q.H. Tuo, and et al. Caveolae and caveolin-1 mediate endocytosis and transcytosis of oxidized low density lipoprotein in endothelial cells Acta Pharmacol. Sin. 31 2010 1336 1342
18. E. Rigamonti, L. Helin, S. Lestavel, and et al. Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages Circ. Res. 97 2005 682 689
19. S.K. Vareed, M. Kakarala, M.T. Ruffin, and et al. Pharmacokinetics of curcumin conjugate metabolites in healthy human subjects Cancer Epidemiol. Biomark. Prev. 17 2008 1411 1417
20. B.B. Aggarwal, and K.B. Harikumar Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases Int. J. Biochem. Cell Biol. 41 2009 40 59
21. A. Olivera, T.W. Moore, F. Hu, and et al. Inhibition of the NF-kappaB signaling pathway by the curcumin analog, 3,5-Bis(2-pyridinylm ethylidene) -4-piperidone (EF31): anti-inflammatory and anti-cancer properties Int. Immunopharmacol. 12 2012 368 377
22. S.Z. Dong, S.P. Zhao, Z.H. Wu, and et al. Curcumin promotes cholesterol efflux from adipocytes related to PPARgamma-LXRalpha-ABCA1 passway Mol. Cell. Biochem. 358 2011 281 285
23. M. Ricote, A.F. Valledor, and C.K. Glass Decoding transcriptional programs regulated by PPARs and LXRs in the macrophage: effects on lipid homeostasis, inflammation, and atherosclerosis Arterioscler. Thromb. Vasc. Biol. 24 2004 230 239
24. T. Miyazaki, K. Morishige, E. Aikawa, and et al. Notch3 signaling promotes M1 macrophage activation and atherosclerosis: a novel therapeutic target Circulation 128 2013 A16302
25. S. Chuengsamarn, S. Rattanamongkolgul, B. Phonrat, and et al. Reduction of atherogenic risk in patients with type 2 diabetes by curcuminoid extract: a randomized controlled trial J. Nutr. Biochem. 25 2014 144 150
26. E.M. Jang, M.S. Choi, U.J. Jung, and et al. Beneficial effects of curcumin on hyperlipidemia and insulin resistance in high-fat-fed hamsters Metabolism 57 2008 1576 1583
27. H.M. Arafa Curcumin attenuates diet-induced hypercholesterolemia in rats Med. Sci. Monit. 11 2005 BR228 234
28. D. Peschel, R. Koerting, and N. Nass Curcumin induces changes in expression of genes involved in cholesterol homeostasis J. Nutr. Biochem. 18 2007 113 119
29. M. RamIrez-Tortosa, M. Mesa, M. Aguilera, and et al. Oral administration of a turmeric extract inhibits LDL oxidation and has hypocholesterolemic effects in rabbits with experimental atherosclerosis Atherosclerosis 147 1999 371 378
30. S.T. Hasan, J.M. Zingg, P. Kwan, and et al. Curcumin modulation of high fat diet-induced atherosclerosis and steatohepatosis in LDL receptor deficient mice Atherosclerosis 232 2014 40 51
31. J.M. Zingg, S.T. Hasan, D. Cowan, and et al. Regulatory effects of curcumin on lipid accumulation in monocytes/macrophages J. Cell. Biochem. 113 2012 833 840
32. K.-j. Min, H.J. Um, K.-H. Cho, and et al. Curcumin inhibits oxLDL-induced CD36 expression and foam cell formation through the inhibition of p38 MAPK phosphorylation Food Chem. Toxicol. 58 2013 77 85
33. A. Canfrán-Duque, Ó. Pastor, R. Quintana-Portillo, and et al. Curcumin promotes exosomes/microvesicles secretion that attenuates lysosomal cholesterol traffic impairment Mol. Nutr. Food Res. 58 2014 687 697