메뉴 건너뛰기




Volumn 10, Issue 9, 2015, Pages

Efficacy and safety of antifibrinolytic agents in reducing perioperative blood loss and transfusion requirements in scoliosis surgery: A systematic review and meta-analysis

Author keywords

[No Author keywords available]

Indexed keywords

AMINOCAPROIC ACID; APROTININ; PLACEBO; TRANEXAMIC ACID; ANTIFIBRINOLYTIC AGENT;

EID: 84946550812     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0137886     Document Type: Review
Times cited : (47)

References (53)
  • 1
    • 33750475365 scopus 로고    scopus 로고
    • Adolescent idiopathic scoliosis: Natural history and long term treatment effects
    • PMID: 16759428
    • Asher MA, Burton DC. Adolescent idiopathic scoliosis: natural history and long term treatment effects. Scoliosis. 2006; 1(1):2. doi: 10.1186/1748-7161-1-2 PMID: 16759428.
    • (2006) Scoliosis , vol.1 , Issue.1 , pp. 2
    • Asher, M.A.1    Burton, D.C.2
  • 2
    • 0020036461 scopus 로고
    • Segmental spinal instrumentation for correction of scoliosis
    • PMID: 7067252
    • Luque ER. Segmental spinal instrumentation for correction of scoliosis. Clinical orthopaedics and related research. 1982;(163: ):192-8. PMID: 7067252.
    • (1982) Clinical Orthopaedics and Related Research , vol.163 , pp. 192-198
    • Luque, E.R.1
  • 3
    • 21244481780 scopus 로고    scopus 로고
    • Correction of adolescent idiopathic scoliosis using thoracic pedicle screw fixation versus hook constructs
    • PMID: 15958886
    • Storer SK, Vitale MG, Hyman JE, Lee FY, Choe JC, Roye DP Jr. Correction of adolescent idiopathic scoliosis using thoracic pedicle screw fixation versus hook constructs. Journal of pediatric orthopedics. 2005; 25(4):415-9. PMID: 15958886.
    • (2005) Journal of Pediatric Orthopedics , vol.25 , Issue.4 , pp. 415-419
    • Storer, S.K.1    Vitale, M.G.2    Hyman, J.E.3    Lee, F.Y.4    Choe, J.C.5    Roye, D.P.6
  • 4
    • 34548394952 scopus 로고    scopus 로고
    • Idiopathic scoliosis treated with Cotrel-Dubousset instrumentation: Evaluation 10 years after surgery
    • PMID: 17762812
    • Bjerkreim I, Steen H, Brox JI. Idiopathic scoliosis treated with Cotrel-Dubousset instrumentation: evaluation 10 years after surgery. Spine. 2007; 32(19):2103-10. doi: 10.1097/BRS.0b013e318145a54a PMID: 17762812.
    • (2007) Spine , vol.32 , Issue.19 , pp. 2103-2110
    • Bjerkreim, I.1    Steen, H.2    Brox, J.I.3
  • 5
    • 0026783152 scopus 로고
    • A trial of desmopressin to reduce blood loss in patients undergoing spinal fusion for idiopathic scoliosis
    • PMID: 1510262
    • Guay J, Reinberg C, Poitras B, David M, Mathews S, Lortie L, et al. A trial of desmopressin to reduce blood loss in patients undergoing spinal fusion for idiopathic scoliosis. Anesthesia and analgesia. 1992; 75(3):405-10. PMID: 1510262.
    • (1992) Anesthesia and Analgesia , vol.75 , Issue.3 , pp. 405-410
    • Guay, J.1    Reinberg, C.2    Poitras, B.3    David, M.4    Mathews, S.5    Lortie, L.6
  • 6
    • 79957869207 scopus 로고    scopus 로고
    • Peri-operative blood loss and extent of fused vertebrae in surgery for adolescent idiopathic scoliosis
    • PMID: 21516986
    • Doi T, Harimaya K, Matsumoto Y, Taniguchi H, Iwamoto Y. Peri-operative blood loss and extent of fused vertebrae in surgery for adolescent idiopathic scoliosis. Fukuoka igaku zasshi = Hukuoka acta medica. 2011; 102(1):8-13. PMID: 21516986.
    • (2011) Fukuoka Igaku Zasshi = Hukuoka Acta Medica , vol.102 , Issue.1 , pp. 8-13
    • Doi, T.1    Harimaya, K.2    Matsumoto, Y.3    Taniguchi, H.4    Iwamoto, Y.5
  • 7
    • 84906307658 scopus 로고    scopus 로고
    • Blood loss during posterior spinal fusion for adolescent idiopathic scoliosis
    • PMID: 24859581
    • Koerner JD, Patel A, Zhao C, Schoenberg C, Mishra A, Vives MJ, et al. Blood loss during posterior spinal fusion for adolescent idiopathic scoliosis. Spine. 2014; 39(18):1479-87. doi: 10.1097/BRS.0000000000000439 PMID: 24859581.
    • (2014) Spine , vol.39 , Issue.18 , pp. 1479-1487
    • Koerner, J.D.1    Patel, A.2    Zhao, C.3    Schoenberg, C.4    Mishra, A.5    Vives, M.J.6
  • 9
    • 70349119744 scopus 로고    scopus 로고
    • Perioperative blood conservation
    • PMID: 19448549
    • Cardone D, Klein AA. Perioperative blood conservation. European journal of anaesthesiology. 2009; 26(9):722-9. doi: 10.1097/EJA.0b013e32832c5280 PMID: 19448549.
    • (2009) European Journal of Anaesthesiology , vol.26 , Issue.9 , pp. 722-729
    • Cardone, D.1    Klein, A.A.2
  • 10
    • 74349113995 scopus 로고    scopus 로고
    • Perioperative management of anemia: Limits of blood transfusion and alternatives to it
    • PMID: 19880828
    • Kumar A. Perioperative management of anemia: limits of blood transfusion and alternatives to it. Cleveland Clinic journal of medicine. 2009; 76 Suppl 4:S112-8. doi: 10.3949/ccjm.76.s4.18 PMID: 19880828.
    • (2009) Cleveland Clinic Journal of Medicine , vol.76 , pp. S112-S118
    • Kumar, A.1
  • 12
    • 0042697567 scopus 로고    scopus 로고
    • The annual cost of blood transfusions in the UK
    • PMID: 12880391
    • Varney SJ, Guest JF. The annual cost of blood transfusions in the UK. Transfusion medicine. 2003; 13 (4):205-18. PMID: 12880391.
    • (2003) Transfusion Medicine , vol.13 , Issue.4 , pp. 205-218
    • Varney, S.J.1    Guest, J.F.2
  • 14
    • 34249913425 scopus 로고    scopus 로고
    • Meta-analysis comparing the effectiveness and adverse outcomes of antifibrinolytic agents in cardiac surgery
    • PMID: 17533182
    • Brown JR, Birkmeyer NJ, O'Connor GT. Meta-analysis comparing the effectiveness and adverse outcomes of antifibrinolytic agents in cardiac surgery. Circulation. 2007; 115(22):2801-13. doi: 10.1161/CIRCULATIONAHA.106.671222 PMID: 17533182.
    • (2007) Circulation , vol.115 , Issue.22 , pp. 2801-2813
    • Brown, J.R.1    Birkmeyer, N.J.2    O'Connor, G.T.3
  • 15
    • 84906351131 scopus 로고    scopus 로고
    • A systematic review and metaanalysis of the topical administration of tranexamic acid in total hip and knee replacement
    • PMID: 25086114
    • Alshryda S, Sukeik M, Sarda P, Blenkinsopp J, Haddad FS, Mason JM. A systematic review and metaanalysis of the topical administration of tranexamic acid in total hip and knee replacement. The bone & joint journal. 2014; 96-B(8):1005-15. doi: 10.1302/0301-620X.96B8.33745 PMID: 25086114.
    • (2014) The Bone & Joint Journal , vol.96 B , Issue.8 , pp. 1005-1015
    • Alshryda, S.1    Sukeik, M.2    Sarda, P.3    Blenkinsopp, J.4    Haddad, F.S.5    Mason, J.M.6
  • 17
  • 18
    • 0242410547 scopus 로고    scopus 로고
    • Aprotinin reduces blood loss during spinal surgery in children
    • PMID: 14595168
    • Cole JW, Murray DJ, Snider RJ, Bassett GS, Bridwell KH, Lenke LG. Aprotinin reduces blood loss during spinal surgery in children. Spine. 2003; 28(21):2482-5. doi: 10.1097/01.BRS.0000090835.45437.7F PMID: 14595168.
    • (2003) Spine , vol.28 , Issue.21 , pp. 2482-2485
    • Cole, J.W.1    Murray, D.J.2    Snider, R.J.3    Bassett, G.S.4    Bridwell, K.H.5    Lenke, L.G.6
  • 19
    • 0742304560 scopus 로고    scopus 로고
    • The effect of amicar on perioperative blood loss in idiopathic scoliosis: The results of a prospective, randomized double-blind study
    • PMID: 14752343
    • Florentino-Pineda I, Thompson GH, Poe-Kochert C, Huang RP, Haber LL, Blakemore LC. The effect of amicar on perioperative blood loss in idiopathic scoliosis: the results of a prospective, randomized double-blind study. Spine. 2004; 29(3):233-8. PMID: 14752343.
    • (2004) Spine , vol.29 , Issue.3 , pp. 233-238
    • Florentino-Pineda, I.1    Thompson, G.H.2    Poe-Kochert, C.3    Huang, R.P.4    Haber, L.L.5    Blakemore, L.C.6
  • 20
    • 3142723632 scopus 로고    scopus 로고
    • Aprotinin to reduced perioperative blood loss in scoliosis surgery
    • Karapurkar A KA, Naik L. aprotinin, to reduced perioperative blood loss in scoliosis surgery Indian J Anaesth 2002; 46(5):378-80.
    • (2002) Indian J Anaesth , vol.46 , Issue.5 , pp. 378-380
    • Karapurkar, A.K.A.1    Naik, L.2
  • 21
    • 0032822549 scopus 로고    scopus 로고
    • Reduction of blood loss and transfusion requirement by aprotinin in posterior lumbar spine fusion
    • PMID: 10475286
    • Lentschener C, Cottin P, Bouaziz H, Mercier FJ, Wolf M, Aljabi Y, et al. Reduction of blood loss and transfusion requirement by aprotinin in posterior lumbar spine fusion. Anesthesia and analgesia. 1999; 89(3):590-7. PMID: 10475286.
    • (1999) Anesthesia and Analgesia , vol.89 , Issue.3 , pp. 590-597
    • Lentschener, C.1    Cottin, P.2    Bouaziz, H.3    Mercier, F.J.4    Wolf, M.5    Aljabi, Y.6
  • 22
    • 0034962649 scopus 로고    scopus 로고
    • A randomized trial of tranexamic acid to reduce blood transfusion for scoliosis surgery
    • PMID: 11429344
    • Neilipovitz DT, Murto K, Hall L, Barrowman NJ, Splinter WM. A randomized trial of tranexamic acid to reduce blood transfusion for scoliosis surgery. Anesthesia and analgesia. 2001; 93(1):82-7. PMID: 11429344.
    • (2001) Anesthesia and Analgesia , vol.93 , Issue.1 , pp. 82-87
    • Neilipovitz, D.T.1    Murto, K.2    Hall, L.3    Barrowman, N.J.4    Splinter, W.M.5
  • 23
    • 16244370709 scopus 로고    scopus 로고
    • Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery
    • PMID: 15791100
    • Sethna NF, Zurakowski D, Brustowicz RM, Bacsik J, Sullivan LJ, Shapiro F. Tranexamic acid reduces intraoperative blood loss in pediatric patients undergoing scoliosis surgery. Anesthesiology. 2005; 102 (4):727-32. PMID: 15791100.
    • (2005) Anesthesiology , vol.102 , Issue.4 , pp. 727-732
    • Sethna, N.F.1    Zurakowski, D.2    Brustowicz, R.M.3    Bacsik, J.4    Sullivan, L.J.5    Shapiro, F.6
  • 24
    • 84901333771 scopus 로고    scopus 로고
    • The relative efficacy of antifibrinolytics in adolescent idiopathic scoliosis: A prospective randomized trial
    • PMID: 24875032
    • Verma K, Errico T, Diefenbach C, Hoelscher C, Peters A, Dryer J, et al. The relative efficacy of antifibrinolytics in adolescent idiopathic scoliosis: a prospective randomized trial. The Journal of bone and joint surgery American volume. 2014; 96(10):e80. doi: 10.2106/JBJS.L.00008 PMID: 24875032.
    • (2014) The Journal of Bone and Joint Surgery American Volume , vol.96 , Issue.10 , pp. e80
    • Verma, K.1    Errico, T.2    Diefenbach, C.3    Hoelscher, C.4    Peters, A.5    Dryer, J.6
  • 25
    • 84857632183 scopus 로고    scopus 로고
    • Which is more effective in adolescent idiopathic scoliosis surgery: Batroxobin, tranexamic acid or a combination?
    • PMID: 21909815
    • Xu C, Wu A, Yue Y. Which is more effective in adolescent idiopathic scoliosis surgery: batroxobin, tranexamic acid or a combination? Archives of orthopaedic and trauma surgery. 2012; 132(1):25-31. doi: 10.1007/s00402-011-1390-6 PMID: 21909815.
    • (2012) Archives of Orthopaedic and Trauma Surgery , vol.132 , Issue.1 , pp. 25-31
    • Xu, C.1    Wu, A.2    Yue, Y.3
  • 28
    • 84868632771 scopus 로고    scopus 로고
    • Antifibrinolytic agents reduce blood loss during pediatric vertebral column resection procedures
    • PMID: 22872217
    • Newton PO, Bastrom TP, Emans JB, Shah SA, Shufflebarger HL, Sponseller PD, et al. Antifibrinolytic agents reduce blood loss during pediatric vertebral column resection procedures. Spine. 2012; 37(23): E1459-63. doi: 10.1097/BRS.0b013e31826c9fe4 PMID: 22872217.
    • (2012) Spine , vol.37 , Issue.23 , pp. E1459-E1463
    • Newton, P.O.1    Bastrom, T.P.2    Emans, J.B.3    Shah, S.A.4    Shufflebarger, H.L.5    Sponseller, P.D.6
  • 29
    • 58149120966 scopus 로고    scopus 로고
    • Efficacy of aprotinin as a blood conservation technique for adult deformity spinal surgery: A retrospective study
    • PMID: 18628710
    • Tayyab NA, Mariller MM, Rivlin M, Berekashvili K, Bitan FD, Casden AM, et al. Efficacy of aprotinin as a blood conservation technique for adult deformity spinal surgery: a retrospective study. Spine. 2008; 33 (16):1775-81. doi: 10.1097/BRS.0b013e31817b87c4 PMID: 18628710.
    • (2008) Spine , vol.33 , Issue.16 , pp. 1775-1781
    • Tayyab, N.A.1    Mariller, M.M.2    Rivlin, M.3    Berekashvili, K.4    Bitan, F.D.5    Casden, A.M.6
  • 30
    • 84866998607 scopus 로고    scopus 로고
    • Does the intraoperative tranexamic acid decrease operative blood loss during posterior spinal fusion for treatment of adolescent idiopathic scoliosis?
    • PMID: 22772572
    • Yagi M, Hasegawa J, Nagoshi N, Iizuka S, Kaneko S, Fukuda K, et al. Does the intraoperative tranexamic acid decrease operative blood loss during posterior spinal fusion for treatment of adolescent idiopathic scoliosis? Spine. 2012; 37(21):E1336-42. doi: 10.1097/BRS.0b013e318266b6e5 PMID: 22772572.
    • (2012) Spine , vol.37 , Issue.21 , pp. E1336-E1342
    • Yagi, M.1    Hasegawa, J.2    Nagoshi, N.3    Iizuka, S.4    Kaneko, S.5    Fukuda, K.6
  • 31
    • 58949087235 scopus 로고    scopus 로고
    • Role of Amicar in surgery for neuromuscular scoliosis
    • PMID: 18981961
    • Thompson GH, Florentino-Pineda I, Poe-Kochert C, Armstrong DG, Son-Hing J. Role of Amicar in surgery for neuromuscular scoliosis. Spine. 2008; 33(24):2623-9. doi: 10.1097/BRS.0b013e318187c046 PMID: 18981961.
    • (2008) Spine , vol.33 , Issue.24 , pp. 2623-2629
    • Thompson, G.H.1    Florentino-Pineda, I.2    Poe-Kochert, C.3    Armstrong, D.G.4    Son-Hing, J.5
  • 32
    • 84878796538 scopus 로고    scopus 로고
    • The effect of tranexamic acid in blood loss and transfusion volume in adolescent idiopathic scoliosis surgery: A single-surgeon experience
    • PMID: 24432083
    • Lykissas MG, Crawford AH, Chan G, Aronson LA, Al-Sayyad MJ. The effect of tranexamic acid in blood loss and transfusion volume in adolescent idiopathic scoliosis surgery: a single-surgeon experience. Journal of children's orthopaedics. 2013; 7(3):245-9. doi: 10.1007/s11832-013-0486-7 PMID: 24432083.
    • (2013) Journal of Children's Orthopaedics , vol.7 , Issue.3 , pp. 245-249
    • Lykissas, M.G.1    Crawford, A.H.2    Chan, G.3    Aronson, L.A.4    Al-Sayyad, M.J.5
  • 33
    • 0035872210 scopus 로고    scopus 로고
    • The Effect of epsilon-aminocaproic acid on perioperative blood loss in patients with idiopathic scoliosis undergoing posterior spinal fusion: A preliminary prospective study
    • PMID: 11413428
    • Florentino-Pineda I, Blakemore LC, Thompson GH, Poe-Kochert C, Adler P, Tripi P. The Effect of epsilon-aminocaproic acid on perioperative blood loss in patients with idiopathic scoliosis undergoing posterior spinal fusion: a preliminary prospective study. Spine. 2001; 26(10):1147-51. PMID: 11413428.
    • (2001) Spine , vol.26 , Issue.10 , pp. 1147-1151
    • Florentino-Pineda, I.1    Blakemore, L.C.2    Thompson, G.H.3    Poe-Kochert, C.4    Adler, P.5    Tripi, P.6
  • 34
    • 84897577204 scopus 로고    scopus 로고
    • Does Amicar affect blood loss in patients with adolescent idiopathic scoliosis treated with pedicle screws and Ponte osteotomies?
    • PMID: 23975447
    • Iorio J, Bennett JT, Orlando G, Singla A, Dakwar E, Bonet H, et al. Does Amicar affect blood loss in patients with adolescent idiopathic scoliosis treated with pedicle screws and Ponte osteotomies? Surgical technology international. 2013; 23:291-5. PMID: 23975447.
    • (2013) Surgical Technology International , vol.23 , pp. 291-295
    • Iorio, J.1    Bennett, J.T.2    Orlando, G.3    Singla, A.4    Dakwar, E.5    Bonet, H.6
  • 35
    • 84888228700 scopus 로고    scopus 로고
    • Antifibrinolytic agents in current anaesthetic practice
    • 2013 PMID: 23661406
    • Ortmann E, Besser MW, Klein AA. Antifibrinolytic agents in current anaesthetic practice. British journal of anaesthesia. 2013; 111 (4)(549-63 (2013)). doi: 10.1093/bja/aet154 PMID: 23661406
    • (2013) British Journal of Anaesthesia , vol.111 , Issue.4 , pp. 549-563
    • Ortmann, E.1    Besser, M.W.2    Klein, A.A.3
  • 36
    • 85016248438 scopus 로고    scopus 로고
    • Normal haemostasis
    • Hoffbrand AV, Catovsky D, Tuddenham EGD, eds. Oxford: Wiley-Blackwell
    • K G, EGD T, JH M. Normal haemostasis. In:Hoffbrand AV, Catovsky D, Tuddenham EGD, eds. 2011; Postgraduate Haematology( Oxford: Wiley-Blackwell, 2011).
    • (2011) 2011; Postgraduate Haematology
    • Egd, T.1    Jh, M.2
  • 37
    • 0010973257 scopus 로고    scopus 로고
    • Therapywith antifibrinolytic agents
    • Colman RW, Hirsch J,Marder V, Clowes A, George J, eds. Philadelphia: LippincottWilliams &Wilkins, 2001
    • U H, J H, V M. Therapywith Antifibrinolytic Agents. In: Colman RW, Hirsch J,Marder V, Clowes A, George J, eds. 2001;Hemostasis and Thrombosis: Basic Principles and Clinical Practice( Philadelphia: LippincottWilliams &Wilkins, 2001).
    • Hemostasis and Thrombosis: Basic Principles and Clinical Practice , vol.2001
  • 38
    • 0020678186 scopus 로고
    • Biochemistry and applications of aprotinin, the kallikrein inhibitor from bovine organs
    • PMID: 6191764
    • Fritz H, Wunderer G. Biochemistry and applications of aprotinin, the kallikrein inhibitor from bovine organs. Arzneimittel-Forschung. 1983; 33(4):479-94. PMID: 6191764.
    • (1983) Arzneimittel-Forschung , vol.33 , Issue.4 , pp. 479-494
    • Fritz, H.1    Wunderer, G.2
  • 39
    • 0029010617 scopus 로고
    • A review of its pharmacology and therapeutic efficacy in reducing blood loss associated with cardiac surgery
    • PMID: 7543841
    • Davis R, Whittington R. Aprotinin. A review of its pharmacology and therapeutic efficacy in reducing blood loss associated with cardiac surgery. Drugs. 1995; 49(6):954-83. PMID: 7543841.
    • (1995) Drugs , vol.49 , Issue.6 , pp. 954-983
    • Davis, R.1    Aprotinin, W.R.2
  • 40
    • 31344467254 scopus 로고    scopus 로고
    • Multicenter Study of perioperative ischemia research
    • G, Ischemia R, Education F. The risk associated with aprotinin in cardiac surgery. PMID: 16436767
    • Mangano DT, Tudor IC, Dietzel C, Multicenter Study of Perioperative Ischemia Research G, Ischemia R, Education F. The risk associated with aprotinin in cardiac surgery. The New England journal of medicine. 2006; 354(4):353-65. doi: 10.1056/NEJMoa051379 PMID: 16436767.
    • (2006) The New England Journal of Medicine , vol.354 , Issue.4 , pp. 353-365
    • Mangano, D.T.1    Tudor, I.C.2    Dietzel, C.3
  • 42
    • 3142675193 scopus 로고    scopus 로고
    • A direct antifibrinolytic agent in major orthopedic surgery
    • PMID: 15239556
    • Samama CM. A direct antifibrinolytic agent in major orthopedic surgery. Orthopedics. 2004; 27(6 Suppl):s675-80. PMID: 15239556.
    • (2004) Orthopedics , vol.27 , Issue.6 , pp. s675-s680
    • Samama, C.M.1
  • 43
    • 0028173373 scopus 로고
    • Natural and synthetic antifibrinolytics in adult cardiac surgery: Efficacy, effectiveness and efficiency
    • PMID: 7530172
    • Hardy JF, Belisle S. Natural and synthetic antifibrinolytics in adult cardiac surgery: efficacy, effectiveness and efficiency. Canadian journal of anaesthesia = Journal canadien d'anesthesie. 1994; 41 (11):1104-12. doi: 10.1007/BF03015662 PMID: 7530172.
    • (1994) Canadian Journal of Anaesthesia = Journal Canadien d'Anesthesie , vol.41 , Issue.11 , pp. 1104-1112
    • Hardy, J.F.1    Belisle, S.2
  • 44
    • 84888297898 scopus 로고    scopus 로고
    • Comparison of epsilon aminocaproic acid and tranexamic Acid in thoracic aortic surgery: Clinical efficacy and safety
    • PMID: 24050855
    • Makhija N, Sarupria A, Kumar Choudhary S, Das S, Lakshmy R, Kiran U. Comparison of epsilon aminocaproic acid and tranexamic Acid in thoracic aortic surgery: clinical efficacy and safety. Journal of cardiothoracic and vascular anesthesia. 2013; 27(6):1201-7. doi: 10.1053/j.jvca.2013.04.003 PMID: 24050855.
    • (2013) Journal of Cardiothoracic and Vascular Anesthesia , vol.27 , Issue.6 , pp. 1201-1207
    • Makhija, N.1    Sarupria, A.2    Kumar Choudhary, S.3    Das, S.4    Lakshmy, R.5    Kiran, U.6
  • 46
    • 84875638067 scopus 로고    scopus 로고
    • Replacement of aprotinin by epsilon-aminocaproic acid in infants undergoing cardiac surgery: Consequences for blood loss and outcome
    • PMID: 23213034
    • Martin K, Gertler R, MacGuill M, Mayr NP, Hapfelmeier A, Horer J, et al. Replacement of aprotinin by epsilon-aminocaproic acid in infants undergoing cardiac surgery: consequences for blood loss and outcome. British journal of anaesthesia. 2013; 110(4):615-21. doi: 10.1093/bja/aes430 PMID: 23213034.
    • (2013) British Journal of Anaesthesia , vol.110 , Issue.4 , pp. 615-621
    • Martin, K.1    Gertler, R.2    MacGuill, M.3    Mayr, N.P.4    Hapfelmeier, A.5    Horer, J.6
  • 47
    • 84901652434 scopus 로고    scopus 로고
    • Increased recombinant activated factor VII use and need for surgical reexploration following a switch from aprotinin to epsilon-aminocaproic acid in infant cardiac surgery
    • PMID: 24809789
    • Scott JP, Costigan DJ, Hoffman GM, Simpson PM, Dasgupta M, Punzalan R, et al. Increased recombinant activated factor VII use and need for surgical reexploration following a switch from aprotinin to epsilon-aminocaproic acid in infant cardiac surgery. Journal of clinical anesthesia. 2014; 26(3):204-11. doi: 10.1016/j.jclinane.2013.10.015 PMID: 24809789.
    • (2014) Journal of Clinical Anesthesia , vol.26 , Issue.3 , pp. 204-211
    • Scott, J.P.1    Costigan, D.J.2    Hoffman, G.M.3    Simpson, P.M.4    Dasgupta, M.5    Punzalan, R.6
  • 49
    • 84867281693 scopus 로고    scopus 로고
    • Risks of harms using antifibrinolytics in cardiac surgery: Systematic review and network meta-analysis of randomised and observational studies
    • PMID: 22968722
    • Hutton B, Joseph L, Fergusson D, Mazer CD, Shapiro S, Tinmouth A. Risks of harms using antifibrinolytics in cardiac surgery: systematic review and network meta-analysis of randomised and observational studies. Bmj. 2012; 345:e5798. doi: 10.1136/bmj.e5798 PMID: 22968722.
    • (2012) Bmj , vol.345 , pp. e5798
    • Hutton, B.1    Joseph, L.2    Fergusson, D.3    Mazer, C.D.4    Shapiro, S.5    Tinmouth, A.6
  • 50
    • 84874594832 scopus 로고    scopus 로고
    • Aprotinin may increase mortality in low and intermediate risk but not in high risk cardiac surgical patients compared to tranexamic acid and epsilon-aminocaproic acid-a meta-analysis of randomised and observational trials of over 30.000 patients
    • PMID: 23483965
    • Meybohm P, Herrmann E, Nierhoff J, Zacharowski K. Aprotinin may increase mortality in low and intermediate risk but not in high risk cardiac surgical patients compared to tranexamic acid and epsilon-aminocaproic acid-a meta-analysis of randomised and observational trials of over 30.000 patients. PloS one. 2013; 8(3):e58009. doi: 10.1371/journal.pone.0058009 PMID: 23483965.
    • (2013) PloS One , vol.8 , Issue.3 , pp. e58009
    • Meybohm, P.1    Herrmann, E.2    Nierhoff, J.3    Zacharowski, K.4
  • 51
    • 58149293358 scopus 로고    scopus 로고
    • The risks of aprotinin and tranexamic acid in cardiac surgery: A one-year follow-up of 1188 consecutive patients
    • PMID: 19020118
    • Martin K, Wiesner G, Breuer T, Lange R, Tassani P. The risks of aprotinin and tranexamic acid in cardiac surgery: a one-year follow-up of 1188 consecutive patients. Anesthesia and analgesia. 2008; 107 (6):1783-90. doi: 10.1213/ane.0b013e318184bc20 PMID: 19020118.
    • (2008) Anesthesia and Analgesia , vol.107 , Issue.6 , pp. 1783-1790
    • Martin, K.1    Wiesner, G.2    Breuer, T.3    Lange, R.4    Tassani, P.5
  • 52
    • 79955054976 scopus 로고    scopus 로고
    • Scoliosis research society morbidity and mortality of adult scoliosis surgery
    • PMID: 21325989
    • Sansur CA, Smith JS, Coe JD, Glassman SD, Berven SH, PollyDW Jr., et al. Scoliosis research society morbidity and mortality of adult scoliosis surgery. Spine. 2011; 36(9):E593-7. doi: 10.1097/BRS.0b013e3182059bfd PMID: 21325989.
    • (2011) Spine , vol.36 , Issue.9 , pp. E593-E597
    • Sansur, C.A.1    Smith, J.S.2    Coe, J.D.3    Glassman, S.D.4    Berven, S.H.5    Polly, D.W.6
  • 53
    • 84904298686 scopus 로고    scopus 로고
    • Thromboembolic complications in children after spinal fusion surgery
    • PMID: 25010014
    • Jain A, Karas DJ, Skolasky RL, Sponseller PD. Thromboembolic complications in children after spinal fusion surgery. Spine. 2014; 39(16):1325-9. doi: 10.1097/BRS.0000000000000402 PMID: 25010014.
    • (2014) Spine , vol.39 , Issue.16 , pp. 1325-1329
    • Jain, A.1    Karas, D.J.2    Skolasky, R.L.3    Sponseller, P.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.