Sulfation modulates the cell uptake, antiradical activity and biological effects of flavonoids in vitro: An examination of quercetin, isoquercitrin and taxifolin

Bioorganic and Medicinal Chemistry

Volumn 23, Issue 17, 2015, Pages 5402-5409

  Roubalová, Lenka ^a   Purchartová, Kateřina ^b   Papoušková, Barbora ^a   Vacek, Jan ^a   Kəen, Vladimír ^b   Ulrichová, Jitka ^a   Vrba, Jiří ^a  

^a PALACKÝ UNIVERSITY   (Czech Republic)

^b INSTITUTE OF MICROBIOLOGY   (Czech Republic)

Author keywords

Antiradical activity; Arylsulfate sulfotransferase; Flavonoids; Gene expression; Metabolism; Sulfate

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ANTIOXIDANT; ARYLSULFATE SULFOTRANSFERASE; BACTERIAL ENZYME; CYTOCHROME P450 1A1; FLAVONOID; HEME OXYGENASE 1; ISOQUERCITRIN; ISOQUERCITRIN 4' O SULFATE; QUERCETIN; QUERCETIN 3' O SULFATE; SULFOTRANSFERASE; TAXIFOLIN; TAXIFOLIN 4' O SULFATE; TRITON X 100; UNCLASSIFIED DRUG; CYP1A1 PROTEIN, HUMAN; QUERCETIN 3'-SULFATE; SCAVENGER;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CELL LINE; CELL METABOLISM; CELLS BY BODY ANATOMY; CONTROLLED STUDY; DESULFITOBACTERIUM; DESULFITOBACTERIUM HAFNIENSE; DRUG METABOLISM; DRUG SCREENING; DRUG SYNTHESIS; DRUG UPTAKE; HEPG2 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RAW264.7 CELL; SULFATION; ANALOGS AND DERIVATIVES; ANIMAL; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

ANIMALS; CELL LINE; CYTOCHROME P-450 CYP1A1; FREE RADICAL SCAVENGERS; GENE EXPRESSION REGULATION; HEME OXYGENASE-1; HEP G2 CELLS; HUMANS; MICE; QUERCETIN;

EID: 84946500465     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2015.07.055     Document Type: Article

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