A novel semisynthetic flavonoid 7-O-galloyltaxifolin upregulates heme oxygenase-1 in RAW264.7 cells via MAPK/Nrf2 pathway

Journal of Medicinal Chemistry

Volumn 56, Issue 3, 2013, Pages 856-866

  Vrba, Jiří ^a   Gažák, Radek ^b   Kuzma, Marek ^b   Papoušková, Barbora ^a   Vacek, Jan ^a   Weiszenstein, Martin ^a   Křen, Vladimír ^b   Ulrichová, Jitka ^a  

^a PALACKÝ UNIVERSITY   (Czech Republic)

^b INSTITUTE OF MICROBIOLOGY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

3 O GALLOYLQUERCETIN; ACETYLCYSTEINE; FLAVONOID 7 O GALLOYLTAXIFOLIN; HEME OXYGENASE 1; KELCH LIKE ECH ASSOCIATED PROTEIN 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; QUERCETIN DERIVATIVE; REACTIVE OXYGEN METABOLITE; TAXIFOLIN; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ACETYLCYSTEINE; ANIMALS; CELL LINE; CELL SURVIVAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEME OXYGENASE-1; MAP KINASE SIGNALING SYSTEM; MICE; NF-E2-RELATED FACTOR 2; PHOSPHORYLATION; QUERCETIN; UP-REGULATION;

EID: 84873920663     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm3013344     Document Type: Article

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