메뉴 건너뛰기




Volumn 128, Issue 11, 2015, Pages 1251.e1-1251.e5

Integration of Genomics in Primary Care

Author keywords

Biomedical informatics; Electronic medical record; Personalized medicine; Pharmacogenetics; Precision medicine

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 2C19; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

EID: 84946492447     PISSN: 00029343     EISSN: 15557162     Source Type: Journal    
DOI: 10.1016/j.amjmed.2015.05.011     Document Type: Review
Times cited : (36)

References (30)
  • 1
    • 78650431963 scopus 로고    scopus 로고
    • Comparative effectiveness research and medical informatics
    • Dec
    • L.W. D'Avolio, W.R. Farwell, and L.D. Fiore Comparative effectiveness research and medical informatics Am J Med 123 12 Suppl 1 2010 Dec e32 e37
    • (2010) Am J Med , vol.123 , Issue.12 , pp. e32-e37
    • D'Avolio, L.W.1    Farwell, W.R.2    Fiore, L.D.3
  • 2
    • 84862620703 scopus 로고    scopus 로고
    • Operational implementation of prospective genotyping for personalized medicine: The design of the Vanderbilt PREDICT project
    • J.M. Pulley, J.C. Denny, J.F. Peterson, and et al. Operational implementation of prospective genotyping for personalized medicine: the design of the Vanderbilt PREDICT project Clin Pharmacol Ther 92 1 2012 87 95
    • (2012) Clin Pharmacol Ther , vol.92 , Issue.1 , pp. 87-95
    • Pulley, J.M.1    Denny, J.C.2    Peterson, J.F.3
  • 4
    • 84920946214 scopus 로고    scopus 로고
    • Exceptional opportunities in medical science: A view from the National Institutes of Health
    • F.S. Collins Exceptional opportunities in medical science: a view from the National Institutes of Health JAMA 313 2 2015 131 132
    • (2015) JAMA , vol.313 , Issue.2 , pp. 131-132
    • Collins, F.S.1
  • 5
    • 77955505564 scopus 로고    scopus 로고
    • Biological, clinical and population relevance of 95 loci for blood lipids
    • T.M. Teslovich, K. Musunuru, A.V. Smith, and et al. Biological, clinical and population relevance of 95 loci for blood lipids Nature 466 2010 707 713
    • (2010) Nature , vol.466 , pp. 707-713
    • Teslovich, T.M.1    Musunuru, K.2    Smith, A.V.3
  • 6
    • 82855175327 scopus 로고    scopus 로고
    • Genotype-informed estimation of risk of coronary heart disease based on genome-wide association data linked to the electronic medical record
    • K. Ding, K.R. Bailey, and I.J. Kullo Genotype-informed estimation of risk of coronary heart disease based on genome-wide association data linked to the electronic medical record BMC Cardiovasc Disord 11 2011 66
    • (2011) BMC Cardiovasc Disord , vol.11 , pp. 66
    • Ding, K.1    Bailey, K.R.2    Kullo, I.J.3
  • 7
    • 84919752308 scopus 로고    scopus 로고
    • Pharmacogenetic meta-analysis of genome-wide association studies of LDL-cholesterol response to statins
    • I. Postmus, S. Trompet, H.A. Deshmukh, and et al. Pharmacogenetic meta-analysis of genome-wide association studies of LDL-cholesterol response to statins Nat Commun 5 2014 5068
    • (2014) Nat Commun , vol.5 , pp. 5068
    • Postmus, I.1    Trompet, S.2    Deshmukh, H.A.3
  • 8
    • 84921691744 scopus 로고    scopus 로고
    • The clinical pharmacogenetics implementation consortium guideline for SLCO1B1 and simvastatin-induced myopathy
    • L.B. Ramsey, S.G. Johnson, K.E. Caudle, and et al. The clinical pharmacogenetics implementation consortium guideline for SLCO1B1 and simvastatin-induced myopathy Clin Pharmacol Ther 96 4 2014 423 428
    • (2014) Clin Pharmacol Ther , vol.96 , Issue.4 , pp. 423-428
    • Ramsey, L.B.1    Johnson, S.G.2    Caudle, K.E.3
  • 9
    • 49949104757 scopus 로고    scopus 로고
    • SLCO1B1 variants and statin-induced myopathy - A genomewide study
    • SEARCH Collaborative Group E. Link, S. Parish, J. Armitage, and et al. SLCO1B1 variants and statin-induced myopathy - a genomewide study N Engl J Med 359 8 2008 789 799
    • (2008) N Engl J Med , vol.359 , Issue.8 , pp. 789-799
    • Link, E.1    Parish, S.2    Armitage, J.3
  • 10
    • 84881539483 scopus 로고    scopus 로고
    • Can EMRs facilitate automated gene-based drug prescribing for cardiovascular disease?
    • J.C. Denny, and R.A. Wilke Can EMRs facilitate automated gene-based drug prescribing for cardiovascular disease? Dialog Cardiovasc Med 17 4 2012 293 300
    • (2012) Dialog Cardiovasc Med , vol.17 , Issue.4 , pp. 293-300
    • Denny, J.C.1    Wilke, R.A.2
  • 11
    • 33947646865 scopus 로고    scopus 로고
    • Potential genetic causes of heterogeneity of treatment effects
    • D.B. Goldstein, A.C. Need, R. Singh, and S.M. Sisodiya Potential genetic causes of heterogeneity of treatment effects Am J Med 120 4 Suppl 1 2007 S21 S25
    • (2007) Am J Med , vol.120 , Issue.4 , pp. S21-S25
    • Goldstein, D.B.1    Need, A.C.2    Singh, R.3    Sisodiya, S.M.4
  • 12
    • 33847685915 scopus 로고    scopus 로고
    • Planning for a national effort to enable and accelerate discoveries in pharmacogenetics: The NIH Pharmacogenetics Research Network
    • R. Long Planning for a national effort to enable and accelerate discoveries in pharmacogenetics: the NIH Pharmacogenetics Research Network Clin Pharmacol Ther 81 3 2007 450 454
    • (2007) Clin Pharmacol Ther , vol.81 , Issue.3 , pp. 450-454
    • Long, R.1
  • 13
    • 79960537881 scopus 로고    scopus 로고
    • Genetics and variable drug response
    • R.A. Wilke, and M.E. Dolan Genetics and variable drug response JAMA 306 3 2011 306 307
    • (2011) JAMA , vol.306 , Issue.3 , pp. 306-307
    • Wilke, R.A.1    Dolan, M.E.2
  • 14
    • 77950348508 scopus 로고    scopus 로고
    • DNA, drugs and chariots: On a decade of pharmacogenomics at the US FDA
    • L.J. Lesko, and I. Zineh DNA, drugs and chariots: on a decade of pharmacogenomics at the US FDA Pharmacogenomics 11 4 2010 507 512
    • (2010) Pharmacogenomics , vol.11 , Issue.4 , pp. 507-512
    • Lesko, L.J.1    Zineh, I.2
  • 15
    • 79951809825 scopus 로고    scopus 로고
    • CPIC: Clinical pharmacogenetics implementation consortium of the pharmacogenomics research network
    • M.V. Relling, and T.E. Klein CPIC: clinical pharmacogenetics implementation consortium of the pharmacogenomics research network Clin Pharmacol Ther 89 3 2011 464 467
    • (2011) Clin Pharmacol Ther , vol.89 , Issue.3 , pp. 464-467
    • Relling, M.V.1    Klein, T.E.2
  • 16
    • 84946507113 scopus 로고    scopus 로고
    • Accessed July 10, 2015
    • Available at: http://www.pharmgkb.org/. Accessed July 10, 2015.
  • 17
    • 58749094444 scopus 로고    scopus 로고
    • Cytochrome P-450 polymorphisms and response to clopidogrel
    • J.L. Mega, S.L. Close, S.D. Wiviott, and et al. Cytochrome P-450 polymorphisms and response to clopidogrel N Engl J Med 360 4 2009 354 362
    • (2009) N Engl J Med , vol.360 , Issue.4 , pp. 354-362
    • Mega, J.L.1    Close, S.L.2    Wiviott, S.D.3
  • 18
    • 84896316037 scopus 로고    scopus 로고
    • Clinical pharmacogenetics implementation: Approaches, successes, and challenges
    • K.W. Weitzel, A.R. Elsey, T.Y. Langaee, and et al. Clinical pharmacogenetics implementation: approaches, successes, and challenges Am J Med Genet C Semin Med Genet 166C 1 2014 56 67
    • (2014) Am J Med Genet C Semin Med Genet , vol.166 C , Issue.1 , pp. 56-67
    • Weitzel, K.W.1    Elsey, A.R.2    Langaee, T.Y.3
  • 19
    • 84883170442 scopus 로고    scopus 로고
    • Clinical Pharmacogenetics Implementation Consortium guidelines for CYP2C19 genotype and clopidogrel therapy: 2013 update
    • S.A. Scott, K. Sangkuhl, C.M. Stein, and et al. Clinical Pharmacogenetics Implementation Consortium guidelines for CYP2C19 genotype and clopidogrel therapy: 2013 update Clin Pharmacol Ther 94 3 2013 317 323
    • (2013) Clin Pharmacol Ther , vol.94 , Issue.3 , pp. 317-323
    • Scott, S.A.1    Sangkuhl, K.2    Stein, C.M.3
  • 20
    • 79960613122 scopus 로고    scopus 로고
    • Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450-2C19 (CYP2C19) genotype and clopidogrel therapy
    • S.A. Scott, K. Sangkuhl, E.E. Gardner, and et al. Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450-2C19 (CYP2C19) genotype and clopidogrel therapy Clin Pharmacol Ther 90 2 2011 328 332
    • (2011) Clin Pharmacol Ther , vol.90 , Issue.2 , pp. 328-332
    • Scott, S.A.1    Sangkuhl, K.2    Gardner, E.E.3
  • 21
    • 84946507114 scopus 로고    scopus 로고
    • Accessed July 10, 2015
    • Available at: http://www.acmg.net/. Accessed July 10, 2015.
  • 22
    • 84920528362 scopus 로고    scopus 로고
    • ACMG Board of Directors. ACMG policy statement: Updated recommendations regarding analysis and reporting of secondary findings in clinical genome-scale sequencing
    • ACMG Board of Directors. ACMG policy statement: updated recommendations regarding analysis and reporting of secondary findings in clinical genome-scale sequencing Genet Med 17 1 2015 68 69
    • (2015) Genet Med , vol.17 , Issue.1 , pp. 68-69
  • 23
    • 78049237784 scopus 로고    scopus 로고
    • Building genetic scores to predict risk of complex diseases in humans: Is it possible?
    • S. Liu, and Y. Song Building genetic scores to predict risk of complex diseases in humans: is it possible? Diabetes 59 11 2010 2729 2731
    • (2010) Diabetes , vol.59 , Issue.11 , pp. 2729-2731
    • Liu, S.1    Song, Y.2
  • 24
    • 84860865023 scopus 로고    scopus 로고
    • A genetic risk score is associated with incident cardiovascular disease and coronary artery calcium: The Framingham Heart Study
    • G. Thanassoulis, G.M. Peloso, M.J. Pencina, and et al. A genetic risk score is associated with incident cardiovascular disease and coronary artery calcium: the Framingham Heart Study Circ Cardiovasc Genet 5 1 2012 113 121
    • (2012) Circ Cardiovasc Genet , vol.5 , Issue.1 , pp. 113-121
    • Thanassoulis, G.1    Peloso, G.M.2    Pencina, M.J.3
  • 25
    • 84946507115 scopus 로고    scopus 로고
    • Recommend whole genome sequencing
    • D. Dimmock Recommend whole genome sequencing N Engl J Med 370 25 2014 2444 2445
    • (2014) N Engl J Med , vol.370 , Issue.25 , pp. 2444-2445
    • Dimmock, D.1
  • 26
    • 84946507116 scopus 로고    scopus 로고
    • Recommend sequencing of cancer genes only, if certain conditions are met
    • W. Burke Recommend sequencing of cancer genes only, if certain conditions are met N Engl J Med 370 25 2014 2443 2444
    • (2014) N Engl J Med , vol.370 , Issue.25 , pp. 2443-2444
    • Burke, W.1
  • 27
    • 84946507117 scopus 로고    scopus 로고
    • Accessed July 10, 2015
    • Available at: http://emerge.mc.vanderbilt.edu. Accessed July 10, 2015.
  • 28
    • 84946507118 scopus 로고    scopus 로고
    • Accessed July 10, 2015
    • Available at: http://www.genome.gov/27554264/. Accessed July 10, 2015.
  • 29
    • 84901766614 scopus 로고    scopus 로고
    • The patient-centered medical home, electronic health records, and quality of care
    • L.M. Kern, A. Edwards, and R. Kaushal The patient-centered medical home, electronic health records, and quality of care Ann Intern Med 160 11 2014 741 749
    • (2014) Ann Intern Med , vol.160 , Issue.11 , pp. 741-749
    • Kern, L.M.1    Edwards, A.2    Kaushal, R.3
  • 30
    • 84946507119 scopus 로고    scopus 로고
    • Accessed July 10, 2015
    • Available at: http://imagenetics.sanfordhealth.org/. Accessed July 10, 2015.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.