DNA, drugs and chariots: On a decade of pharmacogenomics at the US FDA

Pharmacogenomics

Volumn 11, Issue 4, 2010, Pages 507-512

  Lesko, Lawrence J ^a   Zineh, Issam ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

FDA; Genomics; Personalized medicine; Pharmacogenomics; Regulatory

Indexed keywords

ABACAVIR; CARBAMAZEPINE; CETUXIMAB; CHEMOKINE RECEPTOR CCR5; CLOPIDOGREL; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; DASATINIB; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ERLOTINIB; GLUCURONOSYLTRANSFERASE 1A1; HLA B ANTIGEN; IMATINIB; IRINOTECAN; K RAS PROTEIN; MARAVIROC; MERCAPTOPURINE; PACLITAXEL; PANITUMUMAB; PRASUGREL; THIOPURINE METHYLTRANSFERASE; TRASTUZUMAB; WARFARIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; BLEEDING; BONE MARROW SUPPRESSION; BREAST CANCER; CARDIOVASCULAR DISEASE; COLORECTAL CANCER; DRUG EFFICACY; DRUG HYPERSENSITIVITY; DRUG INDUSTRY; DRUG INFORMATION; DRUG LABELING; DRUG SAFETY; ENZYME ACTIVITY; FOOD AND DRUG ADMINISTRATION; GENE MUTATION; GENOTYPE; HUMAN; MEDICAL PRACTICE; MEDICAL SOCIETY; METASTASIS POTENTIAL; NEUTROPENIA; NOTE; PERSONALIZED MEDICINE; PHARMACOGENOMICS; SKIN DISEASE; STEVENS JOHNSON SYNDROME;

DNA; DRUG LABELING; HUMANS; INDIVIDUALIZED MEDICINE; PHARMACEUTICAL PREPARATIONS; PHARMACOGENETICS; UNITED STATES; UNITED STATES FOOD AND DRUG ADMINISTRATION;

EID: 77950348508     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/pgs.10.16     Document Type: Note

References (5)

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4. Zineh I, Lesko LJ: Pharmacogenetics in medicine: barriers, critical factors and a framework for dialogue. Per. Med. 6(4), 359-361 (2009).
5. Contopoulos-Ioannidis DG, Alexiou GA, Gouvias TC et al.: Life cycle of translational research for medical interventions. Science 321(5894), 1298-1299 (2008).