A genetic risk score is associated with incident cardiovascular disease and coronary artery calcium the framingham heart study

Circulation: Cardiovascular Genetics

Volumn 5, Issue 1, 2012, Pages 113-121

  Thanassoulis, George ^a,b,c   Peloso, Gina M ^b   Pencina, Michael J ^b,d   Hoffmann, Udo ^f,g,i   Fox, Caroline S ^b,e,h,i   Cupples, L Adrienne ^b   Levy, Daniel ^b,e   D'Agostino, Ralph B ^b,d   Hwang, Shih Jen ^b,e   O'Donnell, Christopher J ^b,e,f,i  

^a MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b FRAMINGHAM HEART STUDY   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Boston University   (United States)

^e NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^f Department of Internal Medicine   (United States)

^g MASSACHUSETTS GENERAL HOSPITAL   (United States)

^h BRIGHAM AND WOMEN S HOSPITAL   (United States)

ⁱ HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Cardiovascular disease; Coronary heart disease; Genetics; Reclassification; Risk prediction; Single nucleotide polymorphisms

Indexed keywords

CALCIUM; CORONARY ARTERY CALCIUM; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; FEMALE; GENETIC ASSOCIATION; GENETIC RISK; GENETIC RISK SCORE; GENETIC VARIABILITY; HEART INFARCTION; HUMAN; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; PREVALENCE; PRIORITY JOURNAL; SCORING SYSTEM; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ALLELES; CALCINOSIS; CALCIUM; COHORT STUDIES; CORONARY ANGIOGRAPHY; CORONARY DISEASE; FEMALE; FOLLOW-UP STUDIES; GENOME-WIDE ASSOCIATION STUDY; HUMANS; INCIDENCE; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; PREDICTIVE VALUE OF TESTS; PROPORTIONAL HAZARDS MODELS; RISK FACTORS;

EID: 84860865023     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.111.961342     Document Type: Article

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