miR-27b inhibits LDLR and ABCA1 expression but does not influence plasma and hepatic lipid levels in mice

Atherosclerosis

Volumn 243, Issue 2, 2015, Pages 499-509

  Goedeke, Leigh ^a   Rotllan, Noemi ^a   Ramírez, Cristina M ^a   Aranda, Juan F ^a   Canfrán Duque, Alberto ^a   Araldi, Elisa ^a   Fernández Hernando, Ana ^a   Langhi, Cedric ^c   de Cabo, Rafael ^b   Baldán, Ángel ^c   Suárez, Yajaira ^a   Fernández Hernando, Carlos ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE ON AGING   (United States)

^c SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ABCA1; Atherosclerosis; LDLR; Lipid homeostasis; miR 27b; miRNAs

Indexed keywords

ABC TRANSPORTER A1; APOLIPOPROTEIN A1; CHOLESTEROL; LIPID; LOW DENSITY LIPOPROTEIN RECEPTOR; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN ASSOCIATED PROTEIN; MICRORNA; MICRORNA 27B; OLIGONUCLEOTIDE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; ABCA1 PROTEIN, HUMAN; ABCA1 PROTEIN, MOUSE; BIOLOGICAL MARKER; LDLR PROTEIN, HUMAN; LDLRAP1 PROTEIN, HUMAN; MIRN27 MICRORNA, HUMAN; MIRN27 MICRORNA, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; CHOLESTEROL METABOLISM; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LIPID BLOOD LEVEL; LIPID HOMEOSTASIS; LIPID LIVER LEVEL; MALE; METABOLIC REGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHESUS MONKEY; TRANSCRIPTION REGULATION; WILD TYPE; 3' UNTRANSLATED REGION; ANIMAL; BIOLOGY; BLOOD; C57BL MOUSE; CHLOROCEBUS AETHIOPS; COS CELL LINE; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETIC DATABASE; GENETIC TRANSFECTION; GENETICS; HEP-G2 CELL LINE; LIPID DIET; LIVER; METABOLISM; TIME FACTOR;

3' UNTRANSLATED REGIONS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ATP BINDING CASSETTE TRANSPORTER 1; BIOMARKERS; CERCOPITHECUS AETHIOPS; CHOLESTEROL; COMPUTATIONAL BIOLOGY; COS CELLS; DATABASES, GENETIC; DIET, HIGH-FAT; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; HEP G2 CELLS; HUMANS; LIVER; MACACA MULATTA; MALE; MICE, INBRED C57BL; MICRORNAS; RECEPTORS, LDL; TIME FACTORS; TRANSFECTION; TRIGLYCERIDES;

EID: 84946431159     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2015.09.033     Document Type: Article

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