Effects of co-exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin and polychlorinated biphenyls on nonalcoholic fatty liver disease in mice

Environmental Toxicology

Volumn 30, Issue 12, 2015, Pages 1364-1374

  Shan, Qiuli ^a,b   Huang, Fengchen ^a,b   Wang, Jing ^a   Du, Yuguo ^a,b  

^a RESEARCH CENTER FOR ECO ENVIRONMENTAL SCIENCES   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Combined exposure; CYP1A1; NAFLD; Nrf2; PCBs; TCDD

Indexed keywords

CELL DEATH; DISEASES; MAMMALS; ORGANIC CHEMICALS; POLYCHLORINATED BIPHENYLS;

COMBINED EXPOSURE; CYP1A1; NAFLD; NRF2; TCDD;

ORGANIC POLLUTANTS;

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CYTOCHROME P450 1A1; MESSENGER RNA; POLYCHLORINATED BIPHENYL; TRANSCRIPTION FACTOR NRF2; APOLIPOPROTEIN E; NFE2L2 PROTEIN, MOUSE;

BIOASSAY; CHEMICAL POLLUTANT; ORGANIC POLLUTANT; PCB; POLLUTION EXPOSURE; RODENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FATTY LIVER; GENE EXPRESSION; GENETIC ANALYSIS; IN VIVO STUDY; LIVER NECROSIS; MALE; MICROARRAY ANALYSIS; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; ANIMAL; DEFICIENCY; DNA MICROARRAY; DRUG EFFECTS; GENETICS; KNOCKOUT MOUSE; LIVER; METABOLISM; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION;

MUS;

ANIMALS; APOLIPOPROTEINS E; CYTOCHROME P-450 CYP1A1; LIVER; MALE; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, KNOCKOUT; NF-E2-RELATED FACTOR 2; NON-ALCOHOLIC FATTY LIVER DISEASE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS; POLYCHLORINATED BIPHENYLS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; TETRACHLORODIBENZODIOXIN;

EID: 84946414082     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.22006     Document Type: Article

References (32)

1. Angulo P, Lindor KD. 2002. Nonalcoholic fatty liver disease. J Gastroenterol Hepatol 17:S186-S190.
2. Arsenescu V, Arsenescu RI, King V, Swanson H, Cassis LA. 2008. Polychlorinated biphenyl-77 induces adipocyte differentiation and proinflammatory adipokines and promotes obesity and atherosclerosis. Environ Health Perspect 116:761-768.
3. Arsenescu V, Arsenescu R, Parulkar M, Karounos M, Zhang X, Baker N, Cassis LA . 2011. Polychlorinated biphenyl 77 augments angiotensin II-induced atherosclerosis and abdominal aortic aneurysms in male apolipoprotein E deficient mice. Toxicol Appl Pharmacol 257:148-154.
4. Bannister R, Safe S. 1987. Synergistic interactions of 2, 3, 7, 8-TCDD and 2, 2', 4, 4', 5, 5'-hexachlorobiphenyl in C57BL/6J and DBA/2J mice: Role of the Ah receptor. Toxicology 44:159-169.
5. Bhatia LS, Curzen NP, Calder PC, Byrne CD. 2012. Non-alcoholic fatty liver disease: A new and important cardiovascular risk factor? Eur Heart J 33:1190-1200.
6. Bonapace S, Perseghin G, Molon G, Canali G, Bertolini L, Zoppini G, Barbieri E, Targher G . 2012. Nonalcoholic fatty liver disease is associated with left ventricular diastolic dysfunction in patients with type 2 diabetes. Diabetes Care 35:389-395.
7. Cole P, Trichopoulos D, Pastides H, Starr T, Mandel JS. 2003. Dioxin and cancer: A critical review. Regul Toxicol Pharmacol 38:378-388.
8. Crofton KM, Craft ES, Hedge JM, Gennings C, Simmons JE, Carchman RA, Carter WH, DeVito MJ . 2005. Thyroid-hormone-disrupting chemicals: Evidence for dose-dependent additivity or synergism. Environ Health Perspect 113:1549-1554.
9. Daugherty A, Manning MW, Cassis LA. 2000. Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice. J Clin Investig 105:1605-1612.
10. Han SG, Han SS, Toborek M, Hennig B. 2012. EGCG protects endothelial cells against PCB 126-induced inflammation through inhibition of AhR and induction of Nrf2-regulated genes. Toxicol Appl Pharmacol 261:181-188.
11. Hennig B, Meerarani P, Slim R, Toborek M, Daugherty A, Silverstone AE, Robertson LW . 2002. Proinflammatory properties of coplanar PCBs: In vitro and in vivo evidence. Toxicol Appl Pharmacol 181:174-183.
12. Hennig B, Reiterer G, Toborek M, Matveev SV, Daugherty A, Smart E, Robertson LW . 2004. Dietary fat interacts with PCBs to induce changes in lipid metabolism in mice deficient in low-density lipoprotein receptor. Environ Health Perspect 113:83-87.
13. Hong H, Wu J, Shang S, Hu C. 2005. Absorption and fluorescence of chromophoric dissolved organic matter in the Pearl River Estuary, South China. Mar Chem 97:78-89.
14. Irizarry RA, Hobbs B, Collin F, Beazer-Barclay YD, Antonellis KJ, Scherf U, Speed TP . 2003. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4:249-264.
15. Lamle J, Marhenke S, Borlak J, von Wasielewski R, Eriksson CJ, Geffers R, Manns MP, Yamamoto M, Vogel A . 2008. Nuclear factor-eythroid 2-related factor 2 prevents alcohol-induced fulminant liver injury. Gastroenterology 2008:1159-1168.
16. Miniero R, De Felip E, Ferri F, Domenico A. 2001. An overview of TCDD half-life in mammals and its correlation to body weight. Chemosphere 43:839-844.
17. Mishra S, Yadav D, Gupta M, Mishra H, Sharma P. 2013. A study of carotid atherosclerosis in patients with non-alcoholic fatty liver disease. Indian J Clin Biochem 28:79-83.
18. Mozzini C, Pasini AF, Garbin U, Stranieri C, Pasini A, Vallerio P, Cominacini L . 2014. Increased endoplasmic reticulum stress and Nrf2 repression in peripheral blood mononuclear cells of patients with stable coronary artery disease. Free Radic Biol Med 68:178-185.
19. Nagayama J, Tsuji H, Iida T, Nakagawa R, Matsueda T, Hirakawa H, Yanagawa T, Fukushige J, Watanabe T . 2007. Immunologic effects of perinatal exposure to dioxins, PCBs and organochlorine pesticides in Japanese infants. Chemosphere 67:S393-S398.
20. Neuschwander-Tetri BA, Caldwell SH. 2003. Nonalcoholic steatohepatitis: Summary of an AASLD single topic conference. Hepatology 37:1202-1219.
21. Perseghin G, Lattuada G, De Cobelli F, Esposito A, Belloni E, Ntali G, Ragogna F, Canu T, Scifo P, Del Maschio A, Luzi L . 2008. Increased mediastinal fat and impaired left ventricular energy metabolism in young men with newly found fatty liver. Hepatology 47:51-58.
22. Robertson L, Hansen L. 2001. PCBs: Recent advances in environmental toxicology and health effects, Lexington :University Press of Kentucky. p 11.
23. Safe SH. 1994. Polychlorinated biphenyls (PCBs): Environmental impact, biochemical and toxic responses, and implications for risk assessment. Crit Rev Toxicol 24:87-149.
24. Shan Q, Wang J, Huang F, Lv X, Ma M, Du Y. 2014. Augmented atherogenesis in ApoE-null mice co-exposed to polychlorinated biphenyls and 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin. Toxicol Appl Pharmacol 276:136-146.
25. Sorg O, Zennegg M, Schmid P, Fedosyuk R, Valikhnovskyi R, Gaide O, Kniazevych V, Saurat JH . 2009. 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) poisoning in Victor Yushchenko: Identification and measurement of TCDD metabolites. Lancet 374:1179-1185.
26. Stack AS, Altman-Hamamdzic S, Morris PJ, London SD, London L. 1999. Polychlorinated biphenyl mixtures (Aroclors) inhibit LPS-induced murine splenocyte proliferation in vitro. Toxicology 139:137-154.
27. Van Birgelen AP, Fase KM, van der Kolk J, Poiger H, Brouwer A, Seinen W, van den Berg M. 1996. Synergistic effect of 2, 2', 4, 4', 5, 5'-hexachlorobiphenyl and 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin on hepatic porphyrin levels in the rat. Environ Health Perspect 104:550-557.
28. Wan Y, Hu JY, Yang M, An LH, An W, Jin XH, Hattori T, Itoh M . 2005. Characterization of trophic transfer for polychlorinated dibenzo-p-dioxins, dibenzofurans, non- and mono-ortho polychlorinated biphenyls in the marine food web of Bohai Bay, North China. Environ Sci Technol 39:2417-2425.
29. Wang Y, Lu C, Sheng Z, Liu G, Fu Z, Zhu B, Peng S. 2011. Enhanced hepatotoxicity induced by repeated exposure to polychlorinated biphenyls and 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in combination in male rats. J Environ Sci 23:119-124.
30. Xu W, Hellerbrand C, Kohler UA, Bugnon P, Kan YW, Werner S, Beyer TA. 2008. The Nrf2 transcription factor protects from toxin-induced liver injury and fibrosis. Laboratory investigation. J Tech Methods Pathol 88:1068-1078.
31. Zhao Y, Luo K, Fan Z, Huang C, Hu J. 2013. Modulation of benzo[a]pyrene-induced toxic effects in Japanese medaka (Oryzias latipes) by 2, 2', 4, 4'-tetrabromodiphenyl ether. Environ Sci Technol 47:13068-13076.
32. Zoeller RT, Dowling AL, Vas AA. 2000. Developmental exposure to polychlorinated biphenyls exerts thyroid hormone-like effects on the expression of RC3/neurogranin and myelin basic protein messenger ribonucleic acids in the developing rat brain. Endocrinology 141:181-189.