3D Printing of Medicines: Engineering Novel Oral Devices with Unique Design and Drug Release Characteristics

Molecular Pharmaceutics

Volumn 12, Issue 11, 2015, Pages 4077-4084

  Goyanes, Alvaro ^a,b   Wang, Jie ^a   Buanz, Asma ^a   Martínez Pacheco, Ramón ^b   Telford, Richard ^c   Gaisford, Simon ^a,d   Basit, Abdul W ^a,d  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^c UNIVERSITY OF BRADFORD   (United Kingdom)

^d FABRX LTD   (United Kingdom)

Author keywords

acetaminophen; caffeine; controlled release; dynamic bicarbonate dissolution; fused deposition modeling; hot melt extrusion; PVA; Raman mapping; three dimensional printing

Indexed keywords

BICARBONATE; CAFFEINE; PARACETAMOL; POLYVINYL ALCOHOL; POLYMER; TABLET;

ABSORPTION LAG TIME; ADHESION; ARTICLE; BIOMEDICAL ENGINEERING; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISPERSION; DRUG ANALYSIS; DRUG DECOMPOSITION; DRUG DELIVERY DEVICE; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG DOSAGE FORM; DRUG INDUSTRY; DRUG SOLUBILITY; DRUG STRUCTURE; EQUIPMENT DESIGN; HYDROGEN BOND; MELTING POINT; MOLECULAR WEIGHT; ORAL DRUG DELIVERY DEVICE; PARTICLE SIZE; PERSONALIZED MEDICINE; PHARMACOLOGICAL PARAMETERS; PRIORITY JOURNAL; RAMAN SPECTROMETRY; SURFACE AREA; SURFACE PROPERTY; TABLET HARDNESS; TABLET PROPERTY; THREE DIMENSIONAL PRINTING; CHEMISTRY; DEVICES; DRUG FORMULATION; DRUG RELEASE; HUMAN; PHARMACEUTICS; PROCEDURES; TABLET;

ACETAMINOPHEN; CAFFEINE; DRUG COMPOUNDING; DRUG LIBERATION; HUMANS; POLYMERS; PRINTING, THREE-DIMENSIONAL; TABLETS; TECHNOLOGY, PHARMACEUTICAL;

EID: 84946407425     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/acs.molpharmaceut.5b00510     Document Type: Article

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