Crystal structure of the RNA-dependent RNA polymerase from influenza C virus

Nature

Volumn 527, Issue 7576, 2015, Pages 114-117

  Hengrung, Narin ^a,b   El Omari, Kamel ^b   Serna Martin, Itziar ^a   Vreede, Frank T ^a   Cusack, Stephen ^c   Rambo, Robert P ^d   Vonrhein, Clemens ^e   Bricogne, Gérard ^e   Stuart, David I ^b,d   Grimes, Jonathan M ^b,d   Fodor, Ervin ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c CNRS   (France)

^d DIAMOND LIGHT SOURCE LTD   (United Kingdom)

^e GLOBAL PHASING LTD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ENDONUCLEASE; RNA DIRECTED RNA POLYMERASE; VIRUS ENZYME; VIRUS RNA; APOENZYME; CAPPED RNA; PROTEIN BINDING; PROTEIN SUBUNIT; RIBONUCLEOPROTEIN;

AMINO ACID; CELLS AND CELL COMPONENTS; CHEMICAL ANALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVITY; GENOME; PROTEIN; RNA; VIRAL DISEASE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; INFLUENZA C VIRUS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; TRANSCRIPTION INITIATION; X RAY CRYSTALLOGRAPHY; BINDING SITE; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVATION; ENZYMOLOGY; GENETICS; INFLUENZAVIRUS C; METABOLISM; PROTEIN SUBUNIT; PROTEIN TERTIARY STRUCTURE; RNA TRANSLATION;

CERCOPITHECINE HERPESVIRUS 1; INFLUENZA C VIRUS; ORTHOMYXOVIRIDAE; RNA VIRUSES;

APOENZYMES; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ENDONUCLEASES; ENZYME ACTIVATION; INFLUENZAVIRUS C; MODELS, MOLECULAR; PEPTIDE CHAIN INITIATION, TRANSLATIONAL; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; RIBONUCLEOPROTEINS; RNA CAPS; RNA REPLICASE; RNA, VIRAL;

EID: 84946227752     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature15525     Document Type: Article

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