-
2
-
-
0036906509
-
A second gene for peroxisomal HMG-CoA reductase? A genomic reassessment
-
Breitling R., Krisans S.K. A second gene for peroxisomal HMG-CoA reductase? A genomic reassessment. J. Lipid Res. 2002, 43:2031-2036.
-
(2002)
J. Lipid Res.
, vol.43
, pp. 2031-2036
-
-
Breitling, R.1
Krisans, S.K.2
-
3
-
-
84906261489
-
The target for statins, HMG-CoA reductase, is expressed in ductal carcinoma-in situ and may predict patient response to radiotherapy
-
Butt S., Butt T., Jirstrom K., Hartman L., Amini R.M., Zhou W., Warnberg F., Borgquist S. The target for statins, HMG-CoA reductase, is expressed in ductal carcinoma-in situ and may predict patient response to radiotherapy. Ann. Surg. Oncol. 2014, 21:2911-2919.
-
(2014)
Ann. Surg. Oncol.
, vol.21
, pp. 2911-2919
-
-
Butt, S.1
Butt, T.2
Jirstrom, K.3
Hartman, L.4
Amini, R.M.5
Zhou, W.6
Warnberg, F.7
Borgquist, S.8
-
4
-
-
77956989082
-
Dysregulation of the mevalonate pathway promotes transformation
-
Clendening J.W., Pandyra A., Boutros P.C., El Ghamrasni S., Khosravi F., Trentin G.A., Martirosyan A., Hakem A., Hakem R., Jurisica I. Dysregulation of the mevalonate pathway promotes transformation. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:15051-15056.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 15051-15056
-
-
Clendening, J.W.1
Pandyra, A.2
Boutros, P.C.3
El Ghamrasni, S.4
Khosravi, F.5
Trentin, G.A.6
Martirosyan, A.7
Hakem, A.8
Hakem, R.9
Jurisica, I.10
-
5
-
-
84904155440
-
Cancer treatment and survivorship statistics, 2014
-
DeSantis C.E., Lin C.C., Mariotto A.B., Siegel R.L., Stein K.D., Kramer J.L., Alteri R., Robbins A.S., Jemal A. Cancer treatment and survivorship statistics, 2014. CA Cancer J. Clin. 2014, 64:252-271.
-
(2014)
CA Cancer J. Clin.
, vol.64
, pp. 252-271
-
-
DeSantis, C.E.1
Lin, C.C.2
Mariotto, A.B.3
Siegel, R.L.4
Stein, K.D.5
Kramer, J.L.6
Alteri, R.7
Robbins, A.S.8
Jemal, A.9
-
6
-
-
0030808048
-
Mevalonate-regulated mechanisms in cell growth control: role of dolichyl phosphate in expression of the insulin-like growth factor-1 receptor (IGF-1R) in comparison to Ras prenylation and expression of c-myc
-
Dricu A., Wang M., Hjertman M., Malec M., Blegen H., Wejde J., Carlberg M., Larsson O. Mevalonate-regulated mechanisms in cell growth control: role of dolichyl phosphate in expression of the insulin-like growth factor-1 receptor (IGF-1R) in comparison to Ras prenylation and expression of c-myc. Glycobiology 1997, 7:625-633.
-
(1997)
Glycobiology
, vol.7
, pp. 625-633
-
-
Dricu, A.1
Wang, M.2
Hjertman, M.3
Malec, M.4
Blegen, H.5
Wejde, J.6
Carlberg, M.7
Larsson, O.8
-
7
-
-
77953478056
-
De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures
-
Ernst A., Campos B., Meier J., Devens F., Liesenberg F., Wolter M., Reifenberger G., Herold-Mende C., Lichter P., Radlwimmer B. De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures. Oncogene 2010, 29:3411-3422.
-
(2010)
Oncogene
, vol.29
, pp. 3411-3422
-
-
Ernst, A.1
Campos, B.2
Meier, J.3
Devens, F.4
Liesenberg, F.5
Wolter, M.6
Reifenberger, G.7
Herold-Mende, C.8
Lichter, P.9
Radlwimmer, B.10
-
8
-
-
84905500466
-
Induction of cholesterol biosynthesis by archazolid B in T24 bladder cancer cells
-
Hamm R., Chen Y.R., Seo E.J., Zeino M., Wu C.F., Muller R., Yang N.S., Efferth T. Induction of cholesterol biosynthesis by archazolid B in T24 bladder cancer cells. Biochem. Pharmacol. 2014, 91:18-30.
-
(2014)
Biochem. Pharmacol.
, vol.91
, pp. 18-30
-
-
Hamm, R.1
Chen, Y.R.2
Seo, E.J.3
Zeino, M.4
Wu, C.F.5
Muller, R.6
Yang, N.S.7
Efferth, T.8
-
9
-
-
84908364424
-
Up-regulation of cholesterol associated genes as novel resistance mechanism in glioblastoma cells in response to archazolid B
-
Hamm R., Zeino M., Frewert S., Efferth T. Up-regulation of cholesterol associated genes as novel resistance mechanism in glioblastoma cells in response to archazolid B. Toxicol. Appl. Pharmacol. 2014, 281:78-86.
-
(2014)
Toxicol. Appl. Pharmacol.
, vol.281
, pp. 78-86
-
-
Hamm, R.1
Zeino, M.2
Frewert, S.3
Efferth, T.4
-
10
-
-
84862800398
-
TAZ is downregulated by dexamethasone during the differentiation of 3T3-L1 preadipocytes
-
He Q., Huang H.Y., Zhang Y.Y., Li X., Qian S.W., Tang Q.Q. TAZ is downregulated by dexamethasone during the differentiation of 3T3-L1 preadipocytes. Biochem. Biophys. Res. Commun. 2012, 419:573-577.
-
(2012)
Biochem. Biophys. Res. Commun.
, vol.419
, pp. 573-577
-
-
He, Q.1
Huang, H.Y.2
Zhang, Y.Y.3
Li, X.4
Qian, S.W.5
Tang, Q.Q.6
-
11
-
-
84880942838
-
Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators
-
Lavado A., He Y., Pare J., Neale G., Olson E.N., Giovannini M., Cao X. Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development (Cambridge, England) 2013, 140:3323-3334.
-
(2013)
Development (Cambridge, England)
, vol.140
, pp. 3323-3334
-
-
Lavado, A.1
He, Y.2
Pare, J.3
Neale, G.4
Olson, E.N.5
Giovannini, M.6
Cao, X.7
-
12
-
-
84908032460
-
The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap
-
Lavado A., Ware M., Pare J., Cao X. The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap. Development (Cambridge, England) 2014, 141:4182-4193.
-
(2014)
Development (Cambridge, England)
, vol.141
, pp. 4182-4193
-
-
Lavado, A.1
Ware, M.2
Pare, J.3
Cao, X.4
-
13
-
-
84878596483
-
Proteolysis of MOB1 by the ubiquitin ligase praja2 attenuates Hippo signalling and supports glioblastoma growth
-
Lignitto L., Arcella A., Sepe M., Rinaldi L., Delle Donne R., Gallo A., Stefan E., Bachmann V.A., Oliva M.A., Tiziana Storlazzi C. Proteolysis of MOB1 by the ubiquitin ligase praja2 attenuates Hippo signalling and supports glioblastoma growth. Nat. Commun. 2013, 4:1822.
-
(2013)
Nat. Commun.
, vol.4
, pp. 1822
-
-
Lignitto, L.1
Arcella, A.2
Sepe, M.3
Rinaldi, L.4
Delle Donne, R.5
Gallo, A.6
Stefan, E.7
Bachmann, V.A.8
Oliva, M.A.9
Tiziana Storlazzi, C.10
-
14
-
-
84931575156
-
A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth
-
Lin C., Yao E., Chuang P.T. A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth. Dev. Biol. 2015.
-
(2015)
Dev. Biol.
-
-
Lin, C.1
Yao, E.2
Chuang, P.T.3
-
15
-
-
77950813460
-
Genetic variation in 3-hydroxy-3-methylglutaryl CoA reductase modifies the chemopreventive activity of statins for colorectal cancer
-
Lipkin S.M., Chao E.C., Moreno V., Rozek L.S., Rennert H., Pinchev M., Dizon D., Rennert G., Kopelovich L., Gruber S.B. Genetic variation in 3-hydroxy-3-methylglutaryl CoA reductase modifies the chemopreventive activity of statins for colorectal cancer. Cancer Prev. Res. (Phila.) 2010, 3:597-603.
-
(2010)
Cancer Prev. Res. (Phila.)
, vol.3
, pp. 597-603
-
-
Lipkin, S.M.1
Chao, E.C.2
Moreno, V.3
Rozek, L.S.4
Rennert, H.5
Pinchev, M.6
Dizon, D.7
Rennert, G.8
Kopelovich, L.9
Gruber, S.B.10
-
16
-
-
77954770827
-
Targeting YAP and Hippo signaling pathway in liver cancer
-
Liu A.M., Xu M.Z., Chen J., Poon R.T., Luk J.M. Targeting YAP and Hippo signaling pathway in liver cancer. Expert Opin. Ther. Targets 2010, 14:855-868.
-
(2010)
Expert Opin. Ther. Targets
, vol.14
, pp. 855-868
-
-
Liu, A.M.1
Xu, M.Z.2
Chen, J.3
Poon, R.T.4
Luk, J.M.5
-
17
-
-
0026688396
-
Feedback inhibition of polyisoprenyl pyrophosphate synthesis from mevalonate in vitro. Implications for protein prenylation
-
Lutz R.J., McLain T.M., Sinensky M. Feedback inhibition of polyisoprenyl pyrophosphate synthesis from mevalonate in vitro. Implications for protein prenylation. J. Biol. Chem. 1992, 267:7983-7986.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 7983-7986
-
-
Lutz, R.J.1
McLain, T.M.2
Sinensky, M.3
-
18
-
-
77957883342
-
The hippo signaling pathway in development and cancer
-
Pan D. The hippo signaling pathway in development and cancer. Dev. Cell 2010, 19:491-505.
-
(2010)
Dev. Cell
, vol.19
, pp. 491-505
-
-
Pan, D.1
-
19
-
-
84916633921
-
The biology of YAP/TAZ: Hippo signaling and beyond
-
Piccolo S., Dupont S., Cordenonsi M. The biology of YAP/TAZ: Hippo signaling and beyond. Physiol. Rev. 2014, 94:1287-1312.
-
(2014)
Physiol. Rev.
, vol.94
, pp. 1287-1312
-
-
Piccolo, S.1
Dupont, S.2
Cordenonsi, M.3
-
20
-
-
0027163307
-
Differential prenylation of proteins as a function of mevalonate concentration in CHO cells
-
Rilling H.C., Bruenger E., Leining L.M., Buss J.E., Epstein W.W. Differential prenylation of proteins as a function of mevalonate concentration in CHO cells. Arch. Biochem. Biophys. 1993, 301:210-215.
-
(1993)
Arch. Biochem. Biophys.
, vol.301
, pp. 210-215
-
-
Rilling, H.C.1
Bruenger, E.2
Leining, L.M.3
Buss, J.E.4
Epstein, W.W.5
-
21
-
-
84878515271
-
Alkylphospholipids deregulate cholesterol metabolism and induce cell-cycle arrest and autophagy in U-87 MG glioblastoma cells
-
Rios-Marco P., Martin-Fernandez M., Soria-Bretones I., Rios A., Carrasco M.P., Marco C. Alkylphospholipids deregulate cholesterol metabolism and induce cell-cycle arrest and autophagy in U-87 MG glioblastoma cells. Biochim. Biophys. Acta 2013, 1831:1322-1334.
-
(2013)
Biochim. Biophys. Acta
, vol.1831
, pp. 1322-1334
-
-
Rios-Marco, P.1
Martin-Fernandez, M.2
Soria-Bretones, I.3
Rios, A.4
Carrasco, M.P.5
Marco, C.6
-
22
-
-
84873150287
-
Connective tissue growth factor (CTGF/CCN2) is negatively regulated during neuron-glioblastoma interaction
-
Romao L.F., Mendes F.A., Feitosa N.M., Faria J.C., Coelho-Aguiar J.M., de Souza J.M., Moura Neto V., Abreu J.G. Connective tissue growth factor (CTGF/CCN2) is negatively regulated during neuron-glioblastoma interaction. PLoS One 2013, 8.
-
(2013)
PLoS One
, vol.8
-
-
Romao, L.F.1
Mendes, F.A.2
Feitosa, N.M.3
Faria, J.C.4
Coelho-Aguiar, J.M.5
de Souza, J.M.6
Moura Neto, V.7
Abreu, J.G.8
-
23
-
-
84892805731
-
Cancer statistics, 2014
-
Siegel R., Ma J., Zou Z., Jemal A. Cancer statistics, 2014. CA Cancer J. Clin. 2014, 64:9-29.
-
(2014)
CA Cancer J. Clin.
, vol.64
, pp. 9-29
-
-
Siegel, R.1
Ma, J.2
Zou, Z.3
Jemal, A.4
-
24
-
-
84897579255
-
Metabolic control of YAP and TAZ by the mevalonate pathway
-
Sorrentino G., Ruggeri N., Specchia V., Cordenonsi M., Mano M., Dupont S., Manfrin A., Ingallina E., Sommaggio R., Piazza S. Metabolic control of YAP and TAZ by the mevalonate pathway. Nat. Cell Biol. 2014, 16:357-366.
-
(2014)
Nat. Cell Biol.
, vol.16
, pp. 357-366
-
-
Sorrentino, G.1
Ruggeri, N.2
Specchia, V.3
Cordenonsi, M.4
Mano, M.5
Dupont, S.6
Manfrin, A.7
Ingallina, E.8
Sommaggio, R.9
Piazza, S.10
-
25
-
-
55849132186
-
The neurofibromatosis 2 tumor suppressor gene product, merlin, regulates human meningioma cell growth by signaling through YAP
-
Striedinger K., VandenBerg S.R., Baia G.S., McDermott M.W., Gutmann D.H., Lal A. The neurofibromatosis 2 tumor suppressor gene product, merlin, regulates human meningioma cell growth by signaling through YAP. Neoplasia (New York, NY) 2008, 10:1204-1212.
-
(2008)
Neoplasia (New York, NY)
, vol.10
, pp. 1204-1212
-
-
Striedinger, K.1
VandenBerg, S.R.2
Baia, G.S.3
McDermott, M.W.4
Gutmann, D.H.5
Lal, A.6
-
26
-
-
84878368948
-
MT1-MMP-dependent control of skeletal stem cell commitment via a beta1-integrin/YAP/TAZ signaling axis
-
Tang Y., Rowe R.G., Botvinick E.L., Kurup A., Putnam A.J., Seiki M., Weaver V.M., Keller E.T., Goldstein S., Dai J. MT1-MMP-dependent control of skeletal stem cell commitment via a beta1-integrin/YAP/TAZ signaling axis. Dev. Cell 2013, 25:402-416.
-
(2013)
Dev. Cell
, vol.25
, pp. 402-416
-
-
Tang, Y.1
Rowe, R.G.2
Botvinick, E.L.3
Kurup, A.4
Putnam, A.J.5
Seiki, M.6
Weaver, V.M.7
Keller, E.T.8
Goldstein, S.9
Dai, J.10
-
27
-
-
84924959382
-
Targeted delivery of tumor suppressor microRNA-1 by transferrin-conjugated lipopolyplex nanoparticles to patient-derived glioblastoma stem cells
-
Wang X., Huang X., Yang Z., Gallego-Perez D., Ma J., Zhao X., Xie J., Nakano I., Lee L.J. Targeted delivery of tumor suppressor microRNA-1 by transferrin-conjugated lipopolyplex nanoparticles to patient-derived glioblastoma stem cells. Curr. Pharm. Biotechnol. 2014, 15:839-846.
-
(2014)
Curr. Pharm. Biotechnol.
, vol.15
, pp. 839-846
-
-
Wang, X.1
Huang, X.2
Yang, Z.3
Gallego-Perez, D.4
Ma, J.5
Zhao, X.6
Xie, J.7
Nakano, I.8
Lee, L.J.9
-
28
-
-
77950231070
-
CD44 attenuates activation of the Hippo signaling pathway and is a prime therapeutic target for glioblastoma
-
Xu Y., Stamenkovic I., Yu Q. CD44 attenuates activation of the Hippo signaling pathway and is a prime therapeutic target for glioblastoma. Cancer Res. 2010, 70:2455-2464.
-
(2010)
Cancer Res.
, vol.70
, pp. 2455-2464
-
-
Xu, Y.1
Stamenkovic, I.2
Yu, Q.3
-
29
-
-
84928402666
-
HDAC9 promotes glioblastoma growth via TAZ-mediated EGFR pathway activation
-
Yang R., Wu Y., Wang M., Sun Z., Zou J., Zhang Y., Cui H. HDAC9 promotes glioblastoma growth via TAZ-mediated EGFR pathway activation. Oncotarget 2015, 6:7644-7656.
-
(2015)
Oncotarget
, vol.6
, pp. 7644-7656
-
-
Yang, R.1
Wu, Y.2
Wang, M.3
Sun, Z.4
Zou, J.5
Zhang, Y.6
Cui, H.7
|