A porcine model of hypertensive cardiomyopathy: Implications for heart failure with preserved ejection fraction

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 309, Issue 9, 2015, Pages H1407-H1418

  Schwarzl, Michael ^a   Hamdani, Nazha ^b   Seiler, Sebastian ^c   Alogna, Alessio ^d   Manninger, Martin ^d   Reilly, Svetlana ^e   Zirngast, Birgit ^d   Kirsch, Alexander ^d   Steendijk, Paul ^f   Verderber, Jochen ^d   Zweiker, David ^d   Eller, Philipp ^d   Höfler, Gerald ^d   Schauer, Silvia ^d   Eller, Kathrin ^d   Maechler, Heinrich ^d   Pieske, Burkert M ^g   Linke, Wolfgang A ^b   Casadei, Barbara ^e   Post, Heiner ^g  

^a UNIVERSITY HEART CENTER HAMBURG   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

^c Klinikum Starnberg   (Germany)

^d MEDICAL UNIVERSITY OF GRAZ   (Austria)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^g CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Heart failure with preserved ejection fraction; Hypertensive heart disease; Oxidative stress; Pressure volume analysis; Titin

Indexed keywords

AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; CONNECTIN; DOBUTAMINE; ISOPROTEIN; NITRIC OXIDE SYNTHASE; PROTEIN KINASE B; SUPEROXIDE; DEOXYCORTICOSTERONE ACETATE; MINERALOCORTICOID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOMYOPATHY; CONTROLLED STUDY; FEMALE; HEART ATRIUM PACING; HEART DILATATION; HEART FAILURE WITH PRESERVED EJECTION FRACTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE BIOPSY; HEART OUTPUT; HYPERLIPIDEMIA; HYPERTENSION; LANDRACE PIG; NONHUMAN; PORCINE MODEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; ANIMAL; CARDIOMYOPATHIES; CHEMICALLY INDUCED; COMPLICATION; DILATATION, PATHOLOGIC; DISEASE MODEL; HEART ATRIUM; HEART FAILURE; HEART MUSCLE CELL; HEART STROKE VOLUME; HYPERTROPHY; HYPERTROPHY, LEFT VENTRICULAR; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION; PIG; WESTERN DIET;

ANIMALS; CARDIOMYOPATHIES; CONNECTIN; DESOXYCORTICOSTERONE ACETATE; DIET, WESTERN; DILATATION, PATHOLOGIC; DISEASE MODELS, ANIMAL; FEMALE; HEART ATRIA; HEART FAILURE; HYPERLIPIDEMIAS; HYPERTENSION; HYPERTROPHY; HYPERTROPHY, LEFT VENTRICULAR; MINERALOCORTICOIDS; MYOCYTES, CARDIAC; NITRIC OXIDE SYNTHASE; PHOSPHORYLATION; PROTEIN ISOFORMS; PROTO-ONCOGENE PROTEINS C-AKT; STROKE VOLUME; SUPEROXIDES; SWINE;

EID: 84946068680     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00542.2015     Document Type: Article

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