From one generation to the next: A comprehensive account of sympathetic receptor control in branching arteriolar trees

Journal of Physiology

Volumn 593, Issue 14, 2015, Pages 3093-3108

  Al Khazraji, Baraa K ^a   Saleem, Amani ^a   Goldman, Daniel ^a   Jackson, Dwayne N ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR; NEUROPEPTIDE Y1 RECEPTOR; PURINERGIC P2X1 RECEPTOR; ADRENERGIC RECEPTOR STIMULATING AGENT; NEUROPEPTIDE Y RECEPTOR; NEUROPEPTIDE Y-Y1 RECEPTOR; PURINERGIC P2X RECEPTOR AGONIST;

ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERIOLE; ARTICLE; BLOOD FLOW; BRANCHING ARTERIOLAR TREES; CONTROLLED STUDY; ENZYME ACTIVATION; ERYTHROCYTE; HEMODYNAMICS; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SKELETAL MUSCLE; AGONISTS; ANIMAL; DRUG EFFECTS; INNERVATION; PHYSIOLOGY; SPRAGUE DAWLEY RAT; VASCULARIZATION; VASOCONSTRICTION;

ADRENERGIC AGONISTS; ANIMALS; ARTERIOLES; MALE; MUSCLE, SKELETAL; PURINERGIC P2X RECEPTOR AGONISTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NEUROPEPTIDE Y; REGIONAL BLOOD FLOW; SYMPATHETIC NERVOUS SYSTEM; VASOCONSTRICTION;

EID: 84946068182     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/JP270490     Document Type: Article

References (57)

1. Al-Khazraji BK, Novielli NM, Goldman D, Medeiros PJ & Jackson DN (2012). A simple 'streak length method' for quantifying and characterizing red blood cell velocity profiles and blood flow in rat skeletal muscle arterioles. Microcirculation 19, 327-335.
2. Bearden SE, Payne GW, Chisty A & Segal SS (2004). Arteriolar network architecture and vasomotor function with ageing in mouse gluteus maximus muscle. J Physiol 561, 535-545.
3. Boegehold MA & Johnson PC (1988). Response of arteriolar network of skeletal muscle to sympathetic nerve stimulation. Am J Physiol Heart Circ Physiol 254, H919-H928.
4. Buckwalter JB, Taylor JC, Hamann JJ & Clifford PS (2004). Do P2X purinergic receptors regulate skeletal muscle blood flow during exercise? Am J Physiol Heart Circ Physiol 286, H633-H639.
5. Burnstock G (1996). P2 purinoceptors: historical perspective and classification. Ciba Found Symp 198, 1-28; discussion 29-34.
6. Burnstock G (2007). Physiology and pathophysiology of purinergic neurotransmission. Physiol Rev 87, 659-797.
7. Clifford PS & Hellsten Y (2004). Vasodilatory mechanisms in contracting skeletal muscle. J Appl Physiol (1985) 97, 393-403.
8. Dodd LR & Johnson PC (1991). Diameter changes in arteriolar networks of contracting skeletal muscle. Am J Physiol 260, H662-H670.
9. 2+. Am J Physiol Heart Circ Physiol 285, H26-H37.
10. Ekelund U & Erlinge D (1997). In vivo receptor characterization of neuropeptide Y-induced effects in consecutive vascular sections of cat skeletal muscle. Br J Pharmacol 120, 387-392.
11. Ellsworth ML, Liu A, Dawant B, Popel AS & Pittman RN (1987). Analysis of vascular pattern and dimensions in arteriolar networks of the retractor muscle in young hamsters. Microvasc Res 34, 168-183.
12. Erlinge D & Burnstock G (2008). P2 receptors in cardiovascular regulation and disease. Purinergic Signal 4, 1-20.
13. Evanson KW, Stone AJ, Samraj E, Benson T, Prisby R & Kluess HA (2012). Influence of estradiol supplementation on neuropeptide Y neurotransmission in skeletal muscle arterioles of F344 rats. Am J Physiol Regul Integr Comp Physiol 303, R651-R657.
14. Faber JE (1988). In situ analysis of alpha-adrenoceptors on arteriolar and venular smooth muscle in rat skeletal muscle microcirculation. Circ Res 62, 37-50.
15. Galligan JJ, Hess MC, Miller SB & Fink GD (2001). Differential localization of P2 receptor subtypes in mesenteric arteries and veins of normotensive and hypertensive rats. J Pharmacol Exp Ther 296, 478-485.
16. Gitterman DP & Evans RJ (2000). Properties of P2X and P2Y receptors are dependent on artery diameter in the rat mesenteric bed. Br J Pharmacol 131, 1561-1568.
17. Gitterman DP & Evans RJ (2001). Nerve evoked P2X receptor contractions of rat mesenteric arteries; dependence on vessel size and lack of role of L-type calcium channels and calcium induced calcium release. Br J Pharmacol 132, 1201-1208.
18. Goldman D & Popel AS (2000). A computational study of the effect of capillary network anastomoses and tortuosity on oxygen transport. J Theor Biol 206, 181-194.
19. Goldman D & Popel AS (2001). A computational study of the effect of vasomotion on oxygen transport from capillary networks. J Theor Biol 209, 189-199.
20. Hellsten Y, Maclean D, Radegran G, Saltin B & Bangsbo J (1998). Adenosine concentrations in the interstitium of resting and contracting human skeletal muscle. Circulation 98, 6-8.
21. Hirsch D & Zukowska Z (2012). NPY and stress 30 years later: the peripheral view. Cell Mol Neurobiol 32, 645-659.
22. Hirst GD & Jobling P (1989). The distribution of gamma-adrenoceptors and P2 purinoceptors in mesenteric arteries and veins of the guinea-pig. Br J Pharmacol 96, 993-999.
23. Hollah P, Hausberg M, Kosch M, Barenbrock M, Letzel M, Schlatter E & Rahn KH (2001). A novel assay for determination of diadenosine polyphosphates in human platelets: studies in normotensive subjects and in patients with essential hypertension. J Hypertens 19, 237-245.
24. Hopwood AM & Burnstock G (1987). ATP mediates coronary vasoconstriction via P2x-purinoceptors and coronary vasodilatation via P2y-purinoceptors in the isolated perfused rat heart. Eur J Pharmacol 136, 49-54.
25. Jackson DN, Moore AW & Segal SS (2010). Blunting of rapid onset vasodilatation and blood flow restriction in arterioles of exercising skeletal muscle with ageing in male mice. J Physiol 588, 2269-2282.
26. Jackson DN, Noble EG & Shoemaker JK (2004). Y1- and alpha1-receptor control of basal hindlimb vascular tone. Am J Physiol Regul Integr Comp Physiol 287, R228-R233.
27. Jagger JE, Bateman RM, Ellsworth ML & Ellis CG (2001). Role of erythrocyte in regulating local O2 delivery mediated by hemoglobin oxygenation. Am J Physiol Heart Circ Physiol 280, H2833-H2839.
28. Johnson CD, Coney AM & Marshall JM (2001). Roles of norepinephrine and ATP in sympathetically evoked vasoconstriction in rat tail and hindlimb in vivo. Am J Physiol Heart Circ Physiol 281, H2432-H2440.
29. Joshua IG (1991). Neuropeptide Y-induced constriction in small resistance vessels of skeletal muscle. Peptides 12, 37-41.
30. Kiowski W, Hulthen UL, Ritz R & Buhler FR (1983). Alpha 2 adrenoceptor-mediated vasoconstriction of arteries. Clin Pharmacol Ther 34, 565-569.
31. Kirby BS, Crecelius AR, Voyles WF & Dinenno FA (2011). Modulation of postjunctional alpha-adrenergic vasoconstriction during exercise and exogenous ATP infusions in ageing humans. J Physiol 589, 2641-2653.
32. Li L, Jonsson-Rylander AC, Abe K & Zukowska Z (2005). Chronic stress induces rapid occlusion of angioplasty-injured rat carotid artery by activating neuropeptide Y and its Y1 receptors. Arterioscler Thromb Vasc Biol 25, 2075-2080.
33. Malmstrom RE, Balmer KC & Lundberg JM (1997). The neuropeptide Y (NPY) Y1 receptor antagonist BIBP 3226: equal effects on vascular responses to exogenous and endogenous NPY in the pig in vivo. Br J Pharmacol 121, 595-603.
34. Malpas SC (2010). Sympathetic nervous system overactivity and its role in the development of cardiovascular disease. Physiol Rev 90, 513-557.
35. Marshall JM (1982). The influence of the sympathetic nervous system on individual vessels of the microcirculation of skeletal muscle of the rat. J Physiol 332, 169-186.
36. Mo FM & Ballard HJ (2001). The effect of systemic hypoxia on interstitial and blood adenosine, AMP, ADP and ATP in dog skeletal muscle. J Physiol 536, 593-603.
37. Moore AW, Jackson WF & Segal SS (2010). Regional heterogeneity of alpha-adrenoreceptor subtypes in arteriolar networks of mouse skeletal muscle. J Physiol 588, 4261-4274.
38. Mortensen SP, Gonzalez-Alonso J, Nielsen JJ, Saltin B & Hellsten Y (2009). Muscle interstitial ATP and norepinephrine concentrations in the human leg during exercise and ATP infusion. J Appl Physiol (1985) 107, 1757-1762.
39. Mortensen SP, Nyberg M, Winding K & Saltin B (2012). Lifelong physical activity preserves functional sympatholysis and purinergic signalling in the ageing human leg. J Physiol 590, 6227-6236.
40. Mortensen SP, Thaning P, Nyberg M, Saltin B & Hellsten Y (2011). Local release of ATP into the arterial inflow and venous drainage of human skeletal muscle: insight from ATP determination with the intravascular microdialysis technique. J Physiol 589, 1847-1857.
41. Murrant CL & Sarelius IH (2000). Coupling of muscle metabolism and muscle blood flow in capillary units during contraction. Acta Physiol Scand 168, 531-541.
42. Narkiewicz K, Phillips BG, Kato M, Hering D, Bieniaszewski L & Somers VK (2005). Gender-selective interaction between aging, blood pressure, and sympathetic nerve activity. Hypertension 45, 522-525.
43. Novielli NM & Jackson DN (2014). Contraction-evoked vasodilation and functional hyperaemia are compromised in branching skeletal muscle arterioles of young pre-diabetic mice. Acta Physiol (Oxf) 211, 371-384.
44. Nyberg M, Al-Khazraji BK, Mortensen SP, Jackson DN, Ellis CG & Hellsten Y (2013). Effect of extraluminal ATP application on vascular tone and blood flow in skeletal muscle: implications for exercise hyperemia. Am J Physiol Regul Integr Comp Physiol 305, R281-R290.
45. Ohyanagi M, Faber JE & Nishigaki K (1991). Differential activation of alpha 1- and alpha 2-adrenoceptors on microvascular smooth muscle during sympathetic nerve stimulation. Circ Res 68, 232-244.
46. Poole DC, Copp SW, Ferguson SK & Musch TI (2013). Skeletal muscle capillary function: contemporary observations and novel hypotheses. Exp Physiol 98, 1645-1658.
47. Pries AR, Ley K & Gaehtgens P (1986). Generalization of the Fahraeus principle for microvessel networks. Am J Physiol Heart Circ Physiol 251, H1324-H1332.
48. Pries AR, Secomb TW & Gaehtgens P (1995). Structure and hemodynamics of microvascular networks: heterogeneity and correlations. Am J PhysiolHeart Circ Physiol 269, H1713-H1722.
49. Pries AR, Secomb TW, Gaehtgens P & Gross JF (1990). Blood flow in microvascular networks. Experiments and simulation. Circ Res 67, 826-834.
50. Pries AR, Secomb TW, Gessner T, Sperandio MB, Gross JF & Gaehtgens P (1994). Resistance to blood flow in microvessels in vivo. Circ Res 75, 904-915.
51. Ruffolo RR, Jr., Nichols AJ, Stadel JM & Hieble JP (1991). Structure and function of alpha-adrenoceptors. Pharmacol Rev 43, 475-505.
52. Schneider CA, Rasband WS & Eliceiri KW (2012). NIH Image to ImageJ: 25 years of image analysis. Nat Methods 9, 671-675.
53. Segal SS (2005). Regulation of blood flow in the microcirculation. Microcirculation 12, 33-45.
54. Steinmetz M, Bierer S, Hollah P, Rahn KH & Schlatter E (2000). Heterogenous vascular effects of AP5A in different rat resistance arteries are due to heterogenous distribution of P2X and P2Y(1) purinoceptors. J Pharmacol Exp Ther 294, 1182-1187.
55. Stratton JR & Halter JB (1985). Effect of a benzodiazepine (alprazolam) on plasma epinephrine and norepinephrine levels during exercise stress. Am J Cardiol 56, 136-139.
56. West GB, Brown JH & Enquist BJ (1997). A general model for the origin of allometric scaling laws in biology. Science 276, 122-126.
57. Wiedemann MP (1962). Lengths and diameters of peripheral arterial vessels in the living animal. Circ Res 10, 686-690.