Differential localization of P2 receptor subtypes in mesenteric arteries and veins of normotensive and hypertensive rats

Journal of Pharmacology and Experimental Therapeutics

Volumn 296, Issue 2, 2001, Pages 478-485

  Galligan, James J ^a   Hess, Margaret C ^a   Miller, Sara B ^a   Fink, Gregory D ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHYLTHIOADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; DEOXYCORTICOSTERONE ACETATE; PURINE P2 RECEPTOR; PURINE P2X RECEPTOR; PURINE P2X1 RECEPTOR; PURINE P2Y RECEPTOR; PURINE P2Y2 RECEPTOR; PURINE P2Y4 RECEPTOR; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG; URIDINE TRIPHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; DRUG RECEPTOR BINDING; HYPERTENSION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE CONTRACTILITY; TISSUE DISTRIBUTION; VASCULAR SMOOTH MUSCLE; VENOCONSTRICTION;

ADENOSINE TRIPHOSPHATE; ALGORITHMS; ANIMALS; DESOXYCORTICOSTERONE; HYPERTENSION; IMMUNOHISTOCHEMISTRY; MALE; MESENTERIC ARTERIES; MESENTERIC VEINS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PURINERGIC P2; URIDINE TRIPHOSPHATE; VASOCONSTRICTION;

EID: 0035144358     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Imagination and reality in the search for the P2Y receptors
2. Molecular cloning and characterization of rat P2Y4 nucleotide receptor
3. A dual function for adenosine 5'-triphosphate in the regulation of vascular tone. Excitatory cotransmitter with noradrenaline from perivascular nerves and locally released inhibitory intravascular agent
4. PPADS and suramin as antagonists at cloned P2Y and P2U purinoceptors
5. Cloned and transfected P2Y4 receptors: Characterization of a suramin and PPADS insensitive response to UTP
6. Receptors responsive to extracellular pyrimidine nucleotides
7. Evidence from desensitization studies for distinct receptors for ATP and UTP on the rat superior cervical ganglion
8. Regional hemodynamic effects of purinergic P2 receptor subtype agonists in rats
9. Pre- and postsynaptic adrenergic dysfunctions in hypertension
10. Morphological and functional alterations of mesenteric small resistance arteries in early renal hypertension in rats
11. Sympathetic nerve function and vascular reactivity in DOCA-salt hypertensive rats
12. Mechanisms of increased venous smooth muscle tone in deoxycorticosterene-salt hypertension
13. Nomenclature and classification of purinoceptors
14. Towards a revised nomenclature for P1 and P2 receptors
15. Pharmacological dissociation of UTP and ATP elicited contractions and relaxations in isolated rat aorta
16. Frequency characteristics of blood pressure oscillations evoked by sympathetic transmitters, noradrenaline and adenosine triphosphate
17. P2X (purinergic) receptor distributions in rat blood vessels
18. 2+]i, membrane potential and force in isolated rat small arteries
19. ATP as a cotransmitter in perivascular sympathetic-nerves
20. P2 receptor subtypes in the cardiovascular system
21. 2',3'-O-(2,4,6- trinitrophenyl) adenosine 5'-triphosphate (TNP-ATP)-a nanomolar affinity antagonist at rat mesenteric artery P2X receptor ion channels
22. Changes in vascular smooth muscle reactivity in hypertensive rats
23. Differences in responses to norepinephrine and adenosine triphosphate in isolated, perfused mesenteric vascular beds between normotensive and spontaneously hypertensive rats
24. Measurement of arteriole diameter changes by analysis of television images
25. Pharmacology of cloned P2X receptors
26. Further subclassification of ATP receptors based on agonist studies
27. ATP-induced purinoceptor-mediated constriction of isolated, perfused mesenteric beds of the rat
28. Production of hypertension with deoxycorticosterone acetate-impregnated silicone rubber implants
29. Sensitivity and adrenoceptor affinity in the mesenteric artery of the deoxycorticosterone acetate hypertensive rat
30. Effects of purines and pyrimidines on the rat mesenteric arterial bed
31. 2U-purinoceptors in the rat isolated mesenteric arterial bed
32. Characterization of the α-1 adrenoceptors in the mesenteric vasculature from deoxycorticosterone-salt hypertensive rats: Studies on vasoconstriction, radioligand binding and postreceptor events
33. Molecular cloning and characterization of the rat P2Y4 receptor
34. Purinergic and pyrimidinergic receptors as petential drug targets
35. Evidence for a discrete UTP receptor in cardiac endothelial cells
36. Selective antagonism by PPADS at P2X purinoceptors in rabbit isolated blood vessels