Irisin improves endothelial function in obese mice through the AMPK-eNOS pathway

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 309, Issue 9, 2015, Pages H1501-H1508

  Han, Fang ^a   Zhang, Shuxian ^a   Hou, Ningning ^a   Wang, Di ^a   Sun, Xiaodong ^a  

^a WEIFANG MEDICAL UNIVERSITY   (China)

Author keywords

Endothelial function; Irisin; Nitric oxide; Obesity

Indexed keywords

ACETYLCHOLINE; ADENYLATE KINASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; IRISIN; NITRIC OXIDE; PROTEIN KINASE B; SMALL INTERFERING RNA; FIBRONECTIN; FNDC5 PROTEIN, HUMAN; FNDC5 PROTEIN, MOUSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; NOS3 PROTEIN, HUMAN; NOS3 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM; VASODILATATION; ANIMAL; AORTA; C57BL MOUSE; DRUG EFFECTS; LIPID DIET; METABOLISM; PATHOPHYSIOLOGY; PHOSPHORYLATION; UMBILICAL VEIN ENDOTHELIAL CELL;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; AORTA; DIET, HIGH-FAT; ENDOTHELIUM, VASCULAR; FIBRONECTINS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MALE; MICE; MICE, INBRED C57BL; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; OBESITY; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; VASODILATION;

EID: 84946054156     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00443.2015     Document Type: Article

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