Synthesis of 3,4-dihydroxypyrrolidine-2,5-dione and 3,5-dihydroxybenzoic acid derivatives and evaluation of the carbonic anhydrase I and II inhibition

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 30, Issue 6, 2015, Pages 896-900

  Arslan, Mehmet ^a,b   Şentürk, Murat ^c   Fidan, Ismail ^d   Talaz, Oktay ^e   Ekinci, Deniz ^f   Coşgun, Sedat ^b   Supuran, Claudiu T ^g  

^a YALOVA UNIVERSITY   (Turkey)

^b FATIH UNIVERSITY   (Turkey)

^c AGRI IBRAHIM CECEN UNIVERSITY   (Turkey)

^d GEBZE TECHNICAL UNIVERSITY   (Turkey)

^e Karamanolu Mehmetbey University   (Turkey)

^f ONDOKUZ MAYIS UNIVERSITY   (Turkey)

^g UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Benzoic acid; carbonic anhydrase; enzyme inhibitor; hydroxyl; pyrrolidine

Indexed keywords

3,4 DIHYDROXYPYRROLIDINE 2,5 DIONE; 3,5 DIHYDROXYBENZOIC ACID DERIVATIVE; 4 NITROPHENYL ACETATE; ACETAZOLAMIDE; BENZENE DERIVATIVE; BENZOIC ACID DERIVATIVE; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE II; ESTERASE; HYDROXYL GROUP; ISOENZYME; NITRO DERIVATIVE; PYRROLIDINE DERIVATIVE; UNCLASSIFIED DRUG; ALPHA-RESORCYLIC ACID; CARBONATE DEHYDRATASE INHIBITOR; HYDROXYBENZOIC ACID DERIVATIVE; RESORCINOL DERIVATIVE; SUCCINIMIDE DERIVATIVE;

ARTICLE; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; DRUG SCREENING; DRUG SYNTHESIS; DRUG TARGETING; ENZYME ASSAY; ENZYME INHIBITION; PRIORITY JOURNAL; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

CARBONIC ANHYDRASE I; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; HYDROXYBENZOATES; MOLECULAR STRUCTURE; RESORCINOLS; STRUCTURE-ACTIVITY RELATIONSHIP; SUCCINIMIDES;

EID: 84945967600     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756366.2014.983917     Document Type: Article

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