Correction: HuR displaces polypyrimidine tract binding protein to facilitate la binding to the 3' untranslated region and enhances hepatitis C virus replication (Journal of Virology (2015) 89:22 (11356-11371) DOI: 10.1128/JVI.01714-15);HuR displaces polypyrimidine tract binding protein to facilitate la binding to the 3' untranslated region and enhances hepatitis C virus replication

Journal of Virology

Volumn 89, Issue 22, 2015, Pages 11356-11371

  Shwetha, Shivaprasad ^a   Kumar, Anuj ^a   Mullick, Ranajoy ^a   Vasudevan, Deeptha ^a   Mukherjee, Nilanjan ^a   Das, Saumitra ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

HUR PROTEIN; LA ANTIGEN; POLYPYRIMIDINE TRACT BINDING PROTEIN; SMALL INTERFERING RNA; VIRUS RNA; 3' UNTRANSLATED REGION; ELAV LIKE PROTEIN 1; ELAVL1 PROTEIN, HUMAN; LA PROTEIN, HUMAN; NS-5 PROTEIN, HEPATITIS C VIRUS; PHOSPHOPROTEIN; PROTEIN BINDING; RNA BINDING PROTEIN; VIRAL PROTEIN;

3' UNTRANSLATED REGION; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL NUCLEUS; CONTROLLED STUDY; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MOLECULAR CLONING; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA SYNTHESIS; ULTRACENTRIFUGATION; VIRUS GENE; VIRUS REPLICATION; BIOSYNTHESIS; GENETICS; HEPACIVIRUS; HEPATITIS C; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE; VIROLOGY;

3' UNTRANSLATED REGIONS; BINDING SITES; CELL LINE, TUMOR; ELAV-LIKE PROTEIN 1; HEPACIVIRUS; HEPATITIS C; HUMANS; PHOSPHOPROTEINS; POLYPYRIMIDINE TRACT-BINDING PROTEIN; PROTEIN BINDING; RNA INTERFERENCE; RNA, SMALL INTERFERING; RNA, VIRAL; RNA-BINDING PROTEINS; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 84945939067     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00874-19     Document Type: Erratum

References (56)

1. Kuo G, Choo QL, Alter HJ, Gitnick GL, Redeker AG, Purcell RH, Miyamura T, Dienstag JL, Alter MJ, Stevens CE, et al. 1989. An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis. Science 244:362-364. http://dx.doi.org/10.1126/science.2496467.
2. Aizaki H, Lee KJ, Sung VM, Ishiko H, Lai MM. 2004. Characterization of the hepatitis C virus RNA replication complex associated with lipid rafts. Virology 324:450-461. http://dx.doi.org/10.1016/j.virol.2004.03.034.
3. Chatel-Chaix L, Bartenschlager R. 2014. Dengue virus-and hepatitis C virus-induced replication and assembly compartments: the enemy inside-caught in the web. J Virol 88:5907-5911. http://dx.doi.org/10.1128/JVI.03404-13.
4. Frentzen A, Anggakusuma Gurlevik E, Hueging K, Knocke S, Ginkel C, Brown RJ, Heim M, Dill MT, Kroger A, Kalinke U, Kaderali L, Kuehnel F, Pietschmann T. 2014. Cell entry, efficient RNA replication, and production of infectious hepatitis C virus progeny in mouse liver-derived cells. Hepatology 59:78-88. http://dx.doi.org/10.1002/hep.26626.
5. Ali N, Siddiqui A. 1997. The La antigen binds 5' noncoding region of the hepatitis C virus RNA in the context of the initiator AUG codon and stimulates internal ribosome entry site-mediated translation. Proc Natl Acad Sci U S A 94:2249-2254. http://dx.doi.org/10.1073/pnas.94.6.2249.
6. Pudi R, Abhiman S, Srinivasan N, Das S. 2003. Hepatitis C virus internal ribosome entry site-mediated translation is stimulated by specific interaction of independent regions of human La autoantigen. J Biol Chem 278: 12231-12240. http://dx.doi.org/10.1074/jbc. M210287200.
7. Kim JH, Paek KY, Ha SH, Cho S, Choi K, Kim CS, Ryu SH, Jang SK. 2004. A cellular RNA-binding protein enhances internal ribosomal entry site-dependent translation through an interaction downstream of the hepatitis C virus polyprotein initiation codon. Mol Cell Biol 24:7878-7890. http://dx.doi.org/10.1128/MCB.24.18.7878-7890.2004.
8. Hahm B, Cho OH, Kim JE, Kim YK, Kim JH, Oh YL, Jang SK. 1998. Polypyrimidine tract-binding protein interacts with HnRNP L. FEBS Lett 425:401-406. http://dx.doi.org/10.1016/S0014-5793(98)00269-5.
9. Spangberg K, Schwartz S. 1999. Poly(C)-binding protein interacts with the hepatitis C virus 5' untranslated region. J Gen Virol 80:1371-1376. http://dx.doi.org/10.1099/0022-1317-80-6-1371.
10. Fukushi S, Okada M, Stahl J, Kageyama T, Hoshino FB, Katayama K. 2001. Ribosomal protein S5 interacts with the internal ribosomal entry site of hepatitis C virus. J Biol Chem 276:20824-20826. http://dx.doi.org/10.1074/jbc. C100206200.
11. Ray U, Das S. 2011. Interplay between NS3 protease and human La protein regulates translation-replication switch of Hepatitis C virus. Sci Rep 1:1. http://dx.doi.org/10.1038/srep00001.
12. Henke JI, Goergen D, Zheng J, Song Y, Schuttler CG, Fehr C, Junemann C, Niepmann M. 2008. microRNA-122 stimulates translation of hepatitis C virus RNA. EMBO J 27:3300-3310. http://dx.doi.org/10.1038/emboj.2008.244.
13. Sedano CD, Sarnow P. 2014. Hepatitis C virus subverts liver-specific miR-122 to protect the viral genome from exoribonuclease Xrn2. Cell Host Microbe 16:257-264. http://dx.doi.org/10.1016/j.chom.2014.07.006.
14. Yang F, Robotham JM, Nelson HB, Irsigler A, Kenworthy R, Tang H. 2008. Cyclophilin A is an essential cofactor for hepatitis C virus infection and the principal mediator of cyclosporine resistance in vitro. J Virol 82:5269-5278. http://dx.doi.org/10.1128/JVI.02614-07.
15. Watashi K, Ishii N, Hijikata M, Inoue D, Murata T, Miyanari Y, Shimotohno K. 2005. Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase. Mol Cell 19:111-122. http://dx.doi.org/10.1016/j.molcel.2005.05.014.
16. Gao L, Aizaki H, He JW, Lai MM. 2004. Interactions between viral nonstructural proteins and host protein hVAP-33 mediate the formation of hepatitis C virus RNA replication complex on lipid raft. J Virol 78: 3480-3488. http://dx.doi.org/10.1128/JVI.78.7.3480-3488.2004.
17. Reiss S, Rebhan I, Backes P, Romero-Brey I, Erfle H, Matula P, Kaderali L, Poenisch M, Blankenburg H, Hiet MS, Longerich T, Diehl S, Ramirez F, Balla T, Rohr K, Kaul A, Buhler S, Pepperkok R, Lengauer T, Albrecht M, Eils R, Schirmacher P, Lohmann V, Bartenschlager R. 2011. Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment. Cell Host Microbe 9:32-45. http://dx.doi.org/10.1016/j.chom.2010.12.002.
18. Wang H, Perry JW, Lauring AS, Neddermann P, De Francesco R, Tai AW. 2014. Oxysterol-binding protein is a phosphatidylinositol 4-kinase effector required for HCV replication membrane integrity and cholesterol trafficking. Gastroenterology 146:1373-1385.e1-11. http://dx.doi.org/10.1053/j.gastro.2014.02.002.
19. Li Y, Masaki T, Shimakami T, Lemon SM. 2014. hnRNP L and NF90 interact with hepatitis C virus 5'-terminal untranslated RNA and promote efficient replication. J Virol 88:7199-7209. http://dx.doi.org/10.1128/JVI.00225-14.
20. Madan V, Paul D, Lohmann V, Bartenschlager R. 2014. Inhibition of HCV replication by cyclophilin antagonists is linked to replication fitness and occurs by inhibition of membranous web formation. Gastroenterology 146:1361-1372.e1-9. http://dx.doi.org/10.1053/j.gastro.2014.01.055.
21. Janssen HL, Reesink HW, Lawitz EJ, Zeuzem S, Rodriguez-Torres M, Patel K, van der Meer AJ, Patick AK, Chen A, Zhou Y, Persson R, King BD, Kauppinen S, Levin AA, Hodges MR. 2013. Treatment of HCV infection by targeting microRNA. N Engl J Med 368:1685-1694. http://dx.doi.org/10.1056/NEJMoa1209026.
22. Wang L, Jeng KS, Lai MM. 2011. Poly(C)-binding protein 2 interacts with sequences required for viral replication in the hepatitis C virus (HCV) 5' untranslated region and directs HCV RNA replication through circularizing the viral genome. J Virol 85:7954-7964. http://dx.doi.org/10.1128/JVI.00339-11.
23. Kumar A, Ray U, Das S. 2013. Human La protein interaction with GCAC near the initiator AUG enhances hepatitis C Virus RNA replication by promoting linkage between 5' and 3' untranslated regions. J Virol 87: 6713-6726. http://dx.doi.org/10.1128/JVI.00525-13.
24. Paek KY, Kim CS, Park SM, Kim JH, Jang SK. 2008. RNA-binding protein hnRNP D modulates internal ribosome entry site-dependent translation of hepatitis C virus RNA. J Virol 82:12082-12093. http://dx.doi.org/10.1128/JVI.01405-08.
25. Kim CS, Seol SK, Song OK, Park JH, Jang SK. 2007. An RNA-binding protein, hnRNP A1, and a scaffold protein, septin 6, facilitate hepatitis C virus replication. J Virol 81:3852-3865. http://dx.doi.org/10.1128/JVI.01311-06.
26. Lu H, Li W, Noble WS, Payan D, Anderson DC. 2004. Riboproteomics of the hepatitis C virus internal ribosomal entry site. J Proteome Res 3:949-957. http://dx.doi.org/10.1021/pr0499592.
27. Harris D, Zhang Z, Chaubey B, Pandey VN. 2006. Identification of cellular factors associated with the 3'-nontranslated region of the hepatitis C virus genome. Mol Cell Proteomics 5:1006-1018. http://dx.doi.org/10.1074/mcp. M500429-MCP200.
28. Spangberg K, Wiklund L, Schwartz S. 2000. HuR, a protein implicated in oncogene and growth factorm RNA decay, binds to the 3' ends of hepatitis C virus RNA of both polarities. Virology 274:378-390. http://dx.doi.org/10.1006/viro.2000.0461.
29. Korf M, Jarczak D, Beger C, Manns MP, Kruger M. 2005. Inhibition of hepatitis C virus translation and subgenomic replication by siRNAs directed against highly conserved HCV sequence and cellular HCV cofactors. J Hepatol 43:225-234. http://dx.doi.org/10.1016/j.jhep.2005.02.046.
30. Rivas-Aravena A, Ramdohr P, Vallejos M, Valiente-Echeverria F, Dormoy-Raclet V, Rodriguez F, Pino K, Holzmann C, Huidobro-Toro JP, Gallouzi IE, Lopez-Lastra M. 2009. The Elav-like protein HuR exerts translational control of viral internal ribosome entry sites. Virology 392: 178-185. http://dx.doi.org/10.1016/j.virol.2009.06.050.
31. Frese M, Barth K, Kaul A, Lohmann V, Schwarzle V, Bartenschlager R. 2003. Hepatitis C virus RNA replication is resistant to tumour necrosis factor-alpha. J Gen Virol 84:1253-1259. http://dx.doi.org/10.1099/vir.0.18997-0.
32. Kato T, Date T, Miyamoto M, Sugiyama M, Tanaka Y, Orito E, Ohno T, Sugihara K, Hasegawa I, Fujiwara K, Ito K, Ozasa A, Mizokami M, Wakita T. 2005. Detection of anti-hepatitis C virus effects of interferon and ribavirin by a sensitive replicon system. J Clin Microbiol 43:5679-5684. http://dx.doi.org/10.1128/JCM.43.11.5679-5684.2005.
33. Wakita T, Pietschmann T, Kato T, Date T, Miyamoto M, Zhao Z, Murthy K, Habermann A, Krausslich HG, Mizokami M, Bartenschlager R, Liang TJ. 2005. Production of infectious hepatitis C virus in tissue culture from a cloned viral genome. Nat Med 11:791-796. http://dx.doi.org/10.1038/nm1268.
34. Kato T, Date T, Miyamoto M, Furusaka A, Tokushige K, Mizokami M, Wakita T. 2003. Efficient replication of the genotype 2a hepatitis C virus subgenomic replicon. Gastroenterology 125:1808-1817. http://dx.doi.org/10.1053/j.gastro.2003.09.023.
35. Ciofani G, Danti S, D'Alessandro D, Moscato S, Menciassi A. 2010. Assessing cytotoxicity of boron nitride nanotubes: Interference with the MTT assay. Biochem Biophys Res Commun 394:405-411. http://dx.doi.org/10.1016/j.bbrc.2010.03.035.
36. Sambrook J, Russell DW. 2006. Detection of protein-protein interactions using the GST fusion protein pulldown technique. CSH Protoc 2006: pdb.prot3757. http://dx.doi.org/10.1101/pdb.prot3757.
37. Ray PS, Das S. 2002. La autoantigen is required for the internal ribosome entry site-mediated translation of coxsackievirus B3 RNA. Nucleic Acids Res 30:4500-4508. http://dx.doi.org/10.1093/nar/gkf583.
38. Peritz T, Zeng F, Kannanayakal TJ, Kilk K, Eiriksdottir E, Langel U, Eberwine J. 2006. Immunoprecipitation of mRNA-protein complexes. Nat Protoc 1:577-580. http://dx.doi.org/10.1038/nprot.2006.82.
39. Ito T, Lai MM. 1997. Determination of the secondary structure of and cellular protein binding to the 3' untranslated region of the hepatitis C virus RNA genome. J Virol 71:8698-8706.
40. Spangberg K, Goobar-Larsson L, Wahren-Herlenius M, Schwartz S. 1999. The La protein from human liver cells interacts specifically with the U-rich region in the hepatitis C virus 3' untranslated region. J Hum Virol 2:296-307.
41. Domitrovich AM, Diebel KW, Ali N, Sarker S, Siddiqui A. 2005. Role of La autoantigen and polypyrimidine tract-binding protein in HCV replication. Virology 335:72-86. http://dx.doi.org/10.1016/j.virol.2005.02.009.
42. Aragon T, de la Luna S, Novoa I, Carrasco L, Ortin J, Nieto A. 2000. Eukaryotic translation initiation factor 4GI is a cellular target for NS1 protein, a translational activator of influenza virus. Mol Cell Biol 20:6259-6268. http://dx.doi.org/10.1128/MCB.20.17.6259-6268.2000.
43. Yanagi M, St Claire M, Emerson SU, Purcell RH, Bukh J. 1999. In vivo analysis of the 3' untranslated region of the hepatitis C virus after in vitro mutagenesis of an infectious cDNA clone. Proc Natl Acad Sci U S A 96: 2291-2295. http://dx.doi.org/10.1073/pnas.96.5.2291.
44. Li Q, Brass AL, Ng A, Hu Z, Xavier RJ, Liang TJ, Elledge SJ. 2009. A genome-wide genetic screen for host factors required for hepatitis C virus propagation. Proc Natl Acad Sci U S A 106:16410-16415. http://dx.doi.org/10.1073/pnas.0907439106.
45. Li Q, Zhang YY, Chiu S, Hu Z, Lan KH, Cha H, Sodroski C, Zhang F, Hsu CS, Thomas E, Liang TJ. 2014. Integrative functional genomics of hepatitis C virus infection identifies host dependencies in complete viral replication cycle. PLoS Pathog 10:e1004163. http://dx.doi.org/10.1371/journal.ppat.1004163.
46. Dickson AM, Anderson JR, Barnhart MD, Sokoloski KJ, Oko L, Opyrchal M, Galanis E, Wilusz CJ, Morrison TE, Wilusz J. 2012. Dephosphorylation of HuR protein during alphavirus infection is associated with HuR relocalization to the cytoplasm. J Biol Chem 287:36229-36238. http://dx.doi.org/10.1074/jbc. M112.371203.
47. Huang JT, Tseng CP, Liao MH, Lu SC, Yeh WZ, Sakamoto N, Chen CM, Cheng JC. 2013. Hepatitis C virus replication is modulated by the interaction of nonstructural protein NS5B and fatty acid synthase. J Virol 87:4994-5004. http://dx.doi.org/10.1128/JVI.02526-12.
48. Reiss S, Harak C, Romero-Brey I, Radujkovic D, Klein R, Ruggieri A, Rebhan I, Bartenschlager R, Lohmann V. 2013. The lipid kinase phosphatidylinositol-4 kinase III alpha regulates the phosphorylation status of hepatitis C virus NS5A. PLoS Pathog 9:e1003359. http://dx.doi.org/10.1371/journal.ppat.1003359.
49. Weinlich S, Huttelmaier S, Schierhorn A, Behrens SE, Ostareck-Lederer A, Ostareck DH. 2009. IGF2BP1 enhances HCV IRES-mediated translation initiation via the 3' UTR. RNA 15:1528-1542. http://dx.doi.org/10.1261/rna.1578409.
50. Li Q, Pene V, Krishnamurthy S, Cha H, Liang TJ. 2013. Hepatitis C virus infection activates an innate pathway involving IKK-alpha in lipogenesis and viral assembly. Nat Med 19:722-729. http://dx.doi.org/10.1038/nm.3190.
51. Lebedeva S, Jens M, Theil K, Schwanhausser B, Selbach M, Landthaler M, Rajewsky N. 2011. Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR. Mol Cell 43:340-352. http://dx.doi.org/10.1016/j.molcel.2011.06.008.
52. Fialcowitz-White EJ, Brewer BY, Ballin JD, Willis CD, Toth EA, Wilson GM. 2007. Specific protein domains mediate cooperative assembly of HuR oligomers on AU-rich mRNA-destabilizing sequences. J Biol Chem 282:20948-20959. http://dx.doi.org/10.1074/jbc. M701751200.
53. Galban S, Kuwano Y, Pullmann R, Jr, Martindale JL, Kim HH, Lal A, Abdelmohsen K, Yang X, Dang Y, Liu JO, Lewis SM, Holcik M, Gorospe M. 2008. RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor 1α. Mol Cell Biol 28:93-107. http://dx.doi.org/10.1128/MCB.00973-07.
54. Yu TX, Rao JN, Zou T, Liu L, Xiao L, Ouyang M, Cao S, Gorospe M, Wang JY. 2013. Competitive binding of CUGBP1 and HuR to occludin mRNA controls its translation and modulates epithelial barrier function. Mol Biol Cell 24:85-99. http://dx.doi.org/10.1091/mbc. E12-07-0531.
55. Sokoloski KJ, Dickson AM, Chaskey EL, Garneau NL, Wilusz CJ, Wilusz J. 2010. Sindbis virus usurps the cellular HuR protein to stabilize its transcripts and promote productive infections in mammalian and mosquito cells. Cell Host Microbe 8:196-207. http://dx.doi.org/10.1016/j.chom.2010.07.003.
56. Lemay J, Maidou-Peindara P, Bader T, Ennifar E, Rain JC, Benarous R, Liu LX. 2008. HuR interacts with human immunodeficiency virus type 1 reverse transcriptase, and modulates reverse transcription in infected cells. Retrovirology 5:47. http://dx.doi.org/10.1186/1742-4690-5-47.