Dengue virus- and hepatitis C virus-induced replication and assembly compartments: The enemy inside-caught in the web

Journal of Virology

Volumn 88, Issue 11, 2014, Pages 5907-5911

  Chatel Chaix, Laurent ^a   Bartenschlager, Ralf ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALISPORIVIR; CYCLOPHILIN A; CYCLOSPORIN A [4 N METHYLISOLEUCINE]; FAT DROPLET; GLYCOPROTEIN E1; GLYCOPROTEIN E2; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 4A; NONSTRUCTURAL PROTEIN 4B; NONSTRUCTURAL PROTEIN 5A; NONSTRUCTURAL PROTEIN 5B; VIRUS RNA;

ARTICLE; DENGUE VIRUS; ENDOPLASMIC RETICULUM; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; RNA REPLICATION; VIRUS ASSEMBLY; VIRUS CAPSID; VIRUS CORE; VIRUS ENVELOPE; VIRUS GENOME; VIRUS PARTICLE; VIRUS RELEASE; VIRUS REPLICATION;

CYTOPLASMIC VESICLES; DENGUE VIRUS; HEPACIVIRUS; HUMANS; INTRACELLULAR MEMBRANES; VIRUS ASSEMBLY; VIRUS REPLICATION;

EID: 84899845392     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.03404-13     Document Type: Article

References (20)

1. Acosta EG, Kumar A, Bartenschlager R. 2014. Revisiting dengue virushost cell interaction: new insights into molecular and cellular virology. Adv. Virus Res. 88:1-109. http://dx. doi. org/10. 1016/B978-0-12-800098-4. 00001-5.
2. Bartenschlager R, Lohmann V, Penin F. 2013. The molecular and structural basis of advanced antiviral therapy for hepatitis C virus infection. Nat. Rev. Microbiol. 11:482-496. http://dx. doi. org/10. 1038/nrmicro3046.
3. Romero-Brey I, Merz A, Chiramel A, Lee JY, Chlanda P, Haselman U, Santarella-Mellwig R, Habermann A, Hoppe S, Kallis S, Walther P, Antony C, Krijnse-Locker J, Bartenschlager R. 2012. Three-dimensional architecture and biogenesis of membrane structures associated with hepatitis C virus replication. PLoS Pathog. 8:e1003056. http://dx. doi. org/10. 1371/journal. ppat. 1003056.
4. Welsch S, Miller S, Romero-Brey I, Merz A, Bleck CK, Walther P, Fuller SD, Antony C, Krijnse-Locker J, Bartenschlager R. 2009. Composition and three-dimensional architecture of the dengue virus replication and assembly sites. Cell Host Microbe 5:365-375. http://dx. doi. org/10. 1016/j. chom. 2009. 03. 007.
5. Junjhon J, Pennington JG, Edwards TJ, Perera R, Lanman J, Kuhn RJ. 2014. Ultrastructural characterization and three-dimensional architecture of replication sites in dengue virus-infected mosquito cells. J. Virol. 88: 4687-4697. http://dx. doi. org/10. 1128/JVI. 00118-14.
6. Miller S, Kastner S, Krijnse-Locker J, Buhler S, Bartenschlager R. 2007. The non-structural protein 4A of dengue virus is an integral membrane protein inducing membrane alterations in a 2K-regulated manner. J. Biol. Chem. 282:8873-8882. http://dx. doi. org/10. 1074/jbc. M609919200.
7. Ferraris P, Blanchard E, Roingeard P. 2010. Ultrastructural and biochemical analyses of hepatitis C virus-associated host cell membranes. J. Gen. Virol. 91:2230-2237. http://dx. doi. org/10. 1099/vir. 0. 022186-0.
8. Paul D, Hoppe S, Saher G, Krijnse-Locker J, Bartenschlager R. 2013. Morphological and biochemical characterization of the membranous hepatitis C virus replication compartment. J. Virol. 87:10612-10627. http://dx. doi. org/10. 1128/JVI. 01370-13.
9. Egger D, Wolk B, Gosert R, Bianchi L, Blum HE, Moradpour D, Bienz K. 2002. Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex. J. Virol. 76:5974-5984. http://dx. doi. org/10. 1128/JVI. 76. 12. 5974-5984. 2002.
10. Paul D, Romero-Brey I, Gouttenoire J, Stoitsova S, Krijnse-Locker J, Moradpour D, Bartenschlager R. 2011. NS4B self-interaction through conserved C-terminal elements is required for the establishment of functional hepatitis C virus replication complexes. J. Virol. 85:6963-6976. http://dx. doi. org/10. 1128/JVI. 00502-11.
11. Reiss S, Rebhan I, Backes P, Romero-Brey I, Erfle H, Matula P, Kaderali L, Poenisch M, Blankenburg H, Hiet MS, Longerich T, Diehl S, Ramirez F, Balla T, Rohr K, Kaul A, Buhler S, Pepperkok R, Lengauer T, Albrecht M, Eils R, Schirmacher P, Lohmann V, Bartenschlager R. 2011. Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment. Cell Host Microbe 9:32-45. http://dx. doi. org/10. 1016/j. chom. 2010. 12. 002.
12. Madan V, Paul D, Lohmann V, Bartenschlager R. Inhibition of HCV replication by cyclophilin antagonists is linked to replication fitness and occurs by inhibition of membranous web formation. Gastroenterology, in press. http://dx. doi. org/10. 1053/j. gastro. 2014. 01. 055.
13. Reiss S, Harak C, Romero-Brey I, Radujkovic D, Klein R, Ruggieri A, Rebhan I, Bartenschlager R, Lohmann V. 2013. The lipid kinase phosphatidylinositol-4 kinase III alpha regulates the phosphorylation status of hepatitis C virus NS5A. PLoS Pathog. 9:e1003359. http://dx. doi. org/10. 1371/journal. ppat. 1003359.
14. Wang H, Perry JW, Lauring AS, Neddermann P, De FR, Tai AW. Oxysterolbinding protein is a phosphatidylinositol 4-kinase effector required for HCV replication membrane integrity and cholesterol trafficking. Gastroenterology, in press. http://dx. doi. org/10. 1053/j. gastro. 2014. 02. 002.
15. Miyanari Y, Atsuzawa K, Usuda N, Watashi K, Hishiki T, Zayas M, Bartenschlager R, Wakita T, Hijikata M, Shimotohno K. 2007. The lipid droplet is an important organelle for hepatitis C virus production. Nat. Cell Biol. 9:1089-1097. http://dx. doi. org/10. 1038/ncb1631.
16. Shavinskaya A, Boulant S, Penin F, McLauchlan J, Bartenschlager R. 2007. The lipid droplet binding domain of hepatitis C virus core protein is a major determinant for efficient virus assembly. J. Biol. Chem. 282: 37158-37169. http://dx. doi. org/10. 1074/jbc. M707329200.
17. Appel N, Zayas M, Miller S, Krijnse-Locker J, Schaller T, Friebe P, Kallis S, Engel U, Bartenschlager R. 2008. Essential role of domain III of nonstructural protein 5A for hepatitis C virus infectious particle assembly. PLoS Pathog. 4:e1000035. http://dx. doi. org/10. 1371/journal. ppat. 1000035.
18. Lindenbach BD. 2013. Virion assembly and release. Curr. Top. Microbiol. Immunol. 369:199-218. http://dx. doi. org/10. 1007/978-3-642-27340-7_8.
19. Huang H, Sun F, Owen DM, Li W, Chen Y, Gale M, Jr., Ye J. 2007. Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins. Proc. Natl. Acad. Sci. USA. 104:5848-5853. http://dx. doi. org/10. 1073/pnas. 0700760104.
20. Andre P, Komurian-Pradel F, Deforges S, Perret M, Berland JL, Sodoyer M, Pol S, Brechot C, Paranhos-Baccala G, Lotteau V. 2002. Characterization of low-and very-low-density hepatitis C virus RNAcontaining particles. J. Virol. 76:6919-6928. http://dx. doi. org/10. 1128/JVI. 76. 14. 6919-6928. 2002.