-
1
-
-
2642606981
-
-
Bereiter-Hahn J, Munnich A, Woiteneck P. (1998). Dependence of energy metabolism on the density of cells in culture. Cell Struct Funct 23: 85-93. Chaudhary A, King WG,MattalianoMD, Frost JA, Diaz B, Morrison
-
Bereiter-Hahn J, Munnich A, Woiteneck P. (1998). Dependence of energy metabolism on the density of cells in culture. Cell Struct Funct 23: 85-93. Chaudhary A, King WG,MattalianoMD, Frost JA, Diaz B, Morrison
-
-
-
-
2
-
-
0034193426
-
-
DK et al. (2000). Phosphatidylinositol 3-kinase regulates Raf1 through Pak phosphorylation of serine 338. Curr Biol 10: 551-554.
-
DK et al. (2000). Phosphatidylinositol 3-kinase regulates Raf1 through Pak phosphorylation of serine 338. Curr Biol 10: 551-554.
-
-
-
-
3
-
-
0022649091
-
Tumor measurement in the nude mouse
-
Galang CK, Garcia-Ramirez JJ, Solski PA, Westwick JK, Der CJ
-
Euhus DM, Hudd C, LaRegina MC, Johnson FE. (1986). Tumor measurement in the nude mouse. J Surg Oncol 31: 229-234. Galang CK, Garcia-Ramirez JJ, Solski PA, Westwick JK, Der CJ,
-
(1986)
J Surg Oncol
, vol.31
, pp. 229-234
-
-
Euhus, D.M.1
Hudd, C.2
LaRegina, M.C.3
Johnson, F.E.4
-
4
-
-
0029932755
-
Oncogenic Neu/ErbB-2 increases Ets, AP-1, and NF-kappaB-dependent gene expression, and inhibiting Ets activation blocks neu-mediated cellular transformation
-
Neznanov NN et al. (1996). Oncogenic Neu/ErbB-2 increases Ets, AP-1, and NF-kappaB-dependent gene expression, and inhibiting Ets activation blocks neu-mediated cellular transformation. J Biol Chem 271: 7992-7998.
-
(1996)
J Biol Chem
, vol.271
, pp. 7992-7998
-
-
Neznanov, N.N.1
-
5
-
-
0037799232
-
Negative regulation of ERK and Elk by protein kinase B modulates c-Fos transcription
-
Galetic I, Maira SM, Andjelkovic M, Hemmings BA. (2003). Negative regulation of ERK and Elk by protein kinase B modulates c-Fos transcription. J Biol Chem 278: 4416-4423.
-
(2003)
J Biol Chem
, vol.278
, pp. 4416-4423
-
-
Galetic, I.1
Maira, S.M.2
Andjelkovic, M.3
Hemmings, B.A.4
-
6
-
-
32644452086
-
RNA interference in cancer
-
Gartel AL, Kandel ES. (2006). RNA interference in cancer. Biomol Eng 23: 17-34.
-
(2006)
Biomol Eng
, vol.23
, pp. 17-34
-
-
Gartel, A.L.1
Kandel, E.S.2
-
7
-
-
0033604585
-
The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB
-
Kandel ES, Hay N. (1999). The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB. Exp Cell Res 253: 210-229.
-
(1999)
Exp Cell Res
, vol.253
, pp. 210-229
-
-
Kandel, E.S.1
Hay, N.2
-
8
-
-
0036841293
-
Activation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damage
-
Kandel ES, Skeen J, Majewski N, Di Cristofano A, Pandolfi PP, Feliciano CS et al. (2002). Activation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damage. Mol Cell Biol 22: 7831-7841.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7831-7841
-
-
Kandel, E.S.1
Skeen, J.2
Majewski, N.3
Di Cristofano, A.4
Pandolfi, P.P.5
Feliciano, C.S.6
-
9
-
-
0032808154
-
Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria
-
Kennedy SG, Kandel ES, Cross TK, Hay N. (1999). Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria. Mol Cell Biol 19: 5800-5810.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 5800-5810
-
-
Kennedy, S.G.1
Kandel, E.S.2
Cross, T.K.3
Hay, N.4
-
10
-
-
0032511882
-
The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338
-
King AJ, Sun H, Diaz B, Barnard D, Miao W, Bagrodia S et al. (1998). The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338. Nature 396: 180-183.
-
(1998)
Nature
, vol.396
, pp. 180-183
-
-
King, A.J.1
Sun, H.2
Diaz, B.3
Barnard, D.4
Miao, W.5
Bagrodia, S.6
-
11
-
-
0028272507
-
Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane
-
Leevers SJ, Paterson HF, Marshall CJ. (1994). Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane. Nature 369: 411-414.
-
(1994)
Nature
, vol.369
, pp. 411-414
-
-
Leevers, S.J.1
Paterson, H.F.2
Marshall, C.J.3
-
12
-
-
0035224494
-
Interactions between the PI3K and Raf signaling pathways can result in the transformation of hematopoietic cells
-
McCubrey JA, Steelman LS, Abrams SL, Lee JT, Chang F, Bertrand
-
McCubrey JA, Lee JT, Steelman LS, Blalock WL,Moye PW, Chang F et al. (2001). Interactions between the PI3K and Raf signaling pathways can result in the transformation of hematopoietic cells. Cancer Detect Prev 25: 375-393. McCubrey JA, Steelman LS, Abrams SL, Lee JT, Chang F, Bertrand
-
(2001)
Cancer Detect Prev
, vol.25
, pp. 375-393
-
-
McCubrey, J.A.1
Lee, J.T.2
Steelman, L.S.3
Blalock, W.L.4
Moye, P.W.5
Chang, F.6
-
13
-
-
33748063941
-
-
FE et al. (2006). Roles of the RAF/MEK/ERK and PI3K/PTEN/ AKT pathways in malignant transformation and drug resistance. Adv Enzyme Regul 46: 249-279. Mirza AM, Gysin S, Malek N, Nakayama K-I, Roberts JM,
-
FE et al. (2006). Roles of the RAF/MEK/ERK and PI3K/PTEN/ AKT pathways in malignant transformation and drug resistance. Adv Enzyme Regul 46: 249-279. Mirza AM, Gysin S, Malek N, Nakayama K-I, Roberts JM,
-
-
-
-
14
-
-
10044274332
-
Cooperative regulation of the cell division cycle by the protein kinases RAF and AKT
-
McMahon M. (2004). Cooperative regulation of the cell division cycle by the protein kinases RAF and AKT. Mol Cell Biol 24: 10868-10881.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 10868-10881
-
-
McMahon, M.1
-
15
-
-
0033919237
-
Oncogenic transformation of cells by a conditionally active form of the protein kinase Akt/PKB
-
Mirza AM, Kohn AD, Roth RA, McMahon M. (2000). Oncogenic transformation of cells by a conditionally active form of the protein kinase Akt/PKB. Cell Growth Differ 11: 279-292.
-
(2000)
Cell Growth Differ
, vol.11
, pp. 279-292
-
-
Mirza, A.M.1
Kohn, A.D.2
Roth, R.A.3
McMahon, M.4
-
16
-
-
0037163050
-
Regulation of Raf-Akt cross-talk
-
Moelling K, Schad K, Bosse M, Zimmermann S, Schweneker M. (2002). Regulation of Raf-Akt cross-talk. J Biol Chem 277: 31099-31106.
-
(2002)
J Biol Chem
, vol.277
, pp. 31099-31106
-
-
Moelling, K.1
Schad, K.2
Bosse, M.3
Zimmermann, S.4
Schweneker, M.5
-
17
-
-
0025352187
-
Advanced mammalian gene transfer: High titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
-
Morgenstern JP, Land H. (1990). Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res18: 3587-3596.
-
(1990)
Nucleic Acids Res
, vol.18
, pp. 3587-3596
-
-
Morgenstern, J.P.1
Land, H.2
-
18
-
-
2942675416
-
PAK is essential for RAS-induced upregulation of cyclin D1 during the G1 to S transition
-
Nheu T, He H, Hirokawa Y, Walker F, Wood J, Maruta H. (2004). PAK is essential for RAS-induced upregulation of cyclin D1 during the G1 to S transition. Cell Cycle 3: 71-74.
-
(2004)
Cell Cycle
, vol.3
, pp. 71-74
-
-
Nheu, T.1
He, H.2
Hirokawa, Y.3
Walker, F.4
Wood, J.5
Maruta, H.6
-
19
-
-
34248591612
-
Targeting the Raf-MEK-ERK mitogenactivated protein kinase cascade for the treatment of cancer
-
Roberts PJ, Der CJ. (2007). Targeting the Raf-MEK-ERK mitogenactivated protein kinase cascade for the treatment of cancer. Oncogene 26: 3291-3310.
-
(2007)
Oncogene
, vol.26
, pp. 3291-3310
-
-
Roberts, P.J.1
CJ, D.2
-
20
-
-
4644283083
-
Ability of the activated PI3K/Akt oncoproteins to synergize with MEK1 and induce cell cycle progression and abrogate the cytokine-dependence of hematopoietic cells
-
Shelton JG, Blalock WL, White ER, Steelman LS, McCubrey JA. (2004). Ability of the activated PI3K/Akt oncoproteins to synergize with MEK1 and induce cell cycle progression and abrogate the cytokine-dependence of hematopoietic cells. Cell Cycle 3: 503-512.
-
(2004)
Cell Cycle
, vol.3
, pp. 503-512
-
-
Shelton, J.G.1
Blalock, W.L.2
White, E.R.3
Steelman, L.S.4
McCubrey, J.A.5
-
21
-
-
0035958062
-
Akt/PKB activity is required for Ha-Ras-mediated transformation of intestinal epithelial cells
-
Sheng H, Shao J, DuBois RN. (2001). Akt/PKB activity is required for Ha-Ras-mediated transformation of intestinal epithelial cells. J Biol Chem 276: 14498-14504.
-
(2001)
J Biol Chem
, vol.276
, pp. 14498-14504
-
-
Sheng, H.1
Shao, J.2
DuBois, R.N.3
-
22
-
-
58149217066
-
14-3-3beta-Rac1-p21 activated kinase signaling regulates Akt1-mediated cytoskeletal organization, lamellipodia formation and fibronectin matrix assembly
-
Somanath PR, Byzova TV. (2009). 14-3-3beta-Rac1-p21 activated kinase signaling regulates Akt1-mediated cytoskeletal organization, lamellipodia formation and fibronectin matrix assembly. J Cell Physiol 218: 394-404.
-
(2009)
J Cell Physiol
, vol.218
, pp. 394-404
-
-
Somanath, P.R.1
Byzova, T.V.2
-
23
-
-
0028241533
-
Activation of Raf as a result of recruitment to the plasma membrane
-
Stokoe D, Macdonald SG, Cadwallader K, Symons M, Hancock JF. (1994). Activation of Raf as a result of recruitment to the plasma membrane. Science 264: 1463-1467.
-
(1994)
Science
, vol.264
, pp. 1463-1467
-
-
Stokoe, D.1
Macdonald, S.G.2
Cadwallader, K.3
Symons, M.4
Hancock, J.F.5
-
24
-
-
0034624783
-
Regulation of the protein kinase Raf-1 by oncogenic Ras through phosphatidylinositol 3-kinase, Cdc42/Rac and Pak
-
Sun H, King AJ, Diaz HB, Marshall MS. (2000). Regulation of the protein kinase Raf-1 by oncogenic Ras through phosphatidylinositol 3-kinase, Cdc42/Rac and Pak. Current Biology 10: 281-284.
-
(2000)
Current Biology
, vol.10
, pp. 281-284
-
-
Sun, H.1
King, A.J.2
Diaz, H.B.3
Marshall, M.S.4
-
25
-
-
0030811528
-
Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts
-
Tang Y, Chen Z, Ambrose D, Liu J, Gibbs JB, Chernoff J et al. (1997). Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts. Mol Cell Biol 17: 4454-4464.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 4454-4464
-
-
Tang, Y.1
Chen, Z.2
Ambrose, D.3
Liu, J.4
Gibbs, J.B.5
Chernoff, J.6
-
27
-
-
51849111556
-
PI3K pathway alterations in cancer: Variations on a theme
-
Yuan TL, Cantley LC. (2008). PI3K pathway alterations in cancer: variations on a theme. Oncogene 27: 5497-5510.
-
(2008)
Oncogene
, vol.27
, pp. 5497-5510
-
-
Yuan, T.L.1
Cantley, L.C.2
-
28
-
-
0033607633
-
Phosphorylation and regulation of Raf by Akt (protein kinase B)
-
Zimmermann S, Moelling K. (1999). Phosphorylation and regulation of Raf by Akt (protein kinase B). Science 286: 1741-1744.
-
(1999)
Science
, vol.286
, pp. 1741-1744
-
-
Zimmermann, S.1
Moelling, K.2
|