The unfolded protein response and cholesterol biosynthesis link luman/CREB3 to regenerative axon growth in sensory neurons

Journal of Neuroscience

Volumn 35, Issue 43, 2015, Pages 14557-14570

  Ying, Zhengxin ^a,b   Zhai, Ruiling ^a   McLean, Nikki A ^a   Johnston, Jayne M ^a   Misra, Vikram ^a   Verge, Valerie M K ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES   (China)

Author keywords

CHOP; DRG; ER stress; Peripheral nerve regeneration; Srebp1; Xbp1

Indexed keywords

CREB3 PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; GLUCOSE REGULATED PROTEIN 78; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; CHOLESTEROL; CREB3 PROTEIN, RAT; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MESSENGER RNA; SMALL INTERFERING RNA; TUNICAMYCIN;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM; GENE EXPRESSION; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; MALE; NERVE FIBER GROWTH; NERVE INJURY; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSORY NERVE CELL; UNFOLDED PROTEIN RESPONSE; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CYTOLOGY; DRUG EFFECTS; GENE SILENCING; GENETICS; NERVE CRUSH; NERVE FIBER; NERVE REGENERATION; NEURITE; PATHOLOGY; PHYSIOLOGY; PROTEIN UNFOLDING; SCIATIC NEUROPATHY; SPINAL GANGLION; WISTAR RAT;

ANIMALS; AXONS; CELL COUNT; CHOLESTEROL; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; GANGLIA, SPINAL; GENE KNOCKDOWN TECHNIQUES; MALE; NERVE CRUSH; NERVE REGENERATION; NEURITES; PROTEIN UNFOLDING; RATS; RATS, WISTAR; RNA, MESSENGER; RNA, SMALL INTERFERING; SCIATIC NEUROPATHY; SENSORY RECEPTOR CELLS; TUNICAMYCIN;

EID: 84945586145     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0012-15.2015     Document Type: Article

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