Bcl6 middle domain repressor function is required for T follicular helper cell differentiation and utilizes the corepressor MTA3

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 43, 2015, Pages 13324-13329

  Nance, J Philip ^a   Bélanger, Simon ^a   Johnston, Robert J ^a,d   Hu, Joyce K ^a   Takemori, Toshitada ^b   Crotty, Shane ^a,c  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b RIKEN Center for Integrative Medical Sciences   (Japan)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d Bristol Myers Squibb   (United States)

Author keywords

B cell help; Germinal centers; T follicular helper cells

Indexed keywords

B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; METASTASIS ASSOCIATED PROTEIN 3; PROTEIN BCL 6; STAT3 PROTEIN; STAT5 PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; BCL6 PROTEIN, MOUSE; DNA BINDING PROTEIN; MTA3 PROTEIN, MOUSE; PRDM1 PROTEIN, MOUSE; PRIMER DNA; REPRESSOR PROTEIN; TUMOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL FATE; CELL MIGRATION; CELL SURVIVAL; DEACETYLATION; GENE EXPRESSION; HELPER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ACETYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T FOLLICULAR HELPER CELL; ANIMAL; C57BL MOUSE; CHROMATIN IMMUNOPRECIPITATION; FLOW CYTOMETRY; GENETICS; IMMUNOLOGY; METABOLISM; MOLECULAR CLONING; PROTEIN TERTIARY STRUCTURE; REAL TIME POLYMERASE CHAIN REACTION; SITE DIRECTED MUTAGENESIS; TRANSGENIC MOUSE;

ANIMALS; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; CLONING, MOLECULAR; DNA PRIMERS; DNA-BINDING PROTEINS; FLOW CYTOMETRY; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTAGENESIS, SITE-DIRECTED; NEOPLASM PROTEINS; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-BCL-6; REAL-TIME POLYMERASE CHAIN REACTION; REPRESSOR PROTEINS; T-LYMPHOCYTES, HELPER-INDUCER; TRANSCRIPTION FACTORS;

EID: 84945578630     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1507312112     Document Type: Article

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