Determination of UCP1 expression in subcutaneous and perirenal adipose tissues of patients with hypertension

Endocrine

Volumn 50, Issue 2, 2015, Pages 413-423

  Li, Xueqin ^a,b   Liu, Juan ^a   Wang, Gongcheng ^b   Yu, Jing ^a   Sheng, Yunlu ^a   Wang, Chen ^a   Lv, Yifan ^a   Lv, Shan ^a   Qi, Hanmei ^a   Di, Wenjuan ^a   Yin, Changjun ^a   Ding, Guoxian ^a  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Hypertension; Perirenal adipose tissue; Uncoupling protein 1

Indexed keywords

MESSENGER RNA; UNCOUPLING PROTEIN 1; ION CHANNEL; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN;

ARTICLE; BODY MASS; BROWN ADIPOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HUMAN; HUMAN TISSUE; HYPERTENSION; IMMUNOHISTOCHEMISTRY; KIDNEY SURGERY; PERIRENAL FAT; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SUBCUTANEOUS FAT; UCP1 GENE; WESTERN BLOTTING; ADIPOCYTE; ADIPOSE TISSUE; ADULT; AGED; CYTOLOGY; FEMALE; KIDNEY; LAPAROSCOPY; MALE; METABOLISM; MIDDLE AGED;

ADIPOCYTES; ADIPOSE TISSUE; ADULT; AGED; FEMALE; HUMANS; HYPERTENSION; ION CHANNELS; KIDNEY; LAPAROSCOPY; MALE; MIDDLE AGED; MITOCHONDRIAL PROTEINS; RNA, MESSENGER; SUBCUTANEOUS FAT;

EID: 84945443551     PISSN: 1355008X     EISSN: 15590100     Source Type: Journal    
DOI: 10.1007/s12020-015-0572-3     Document Type: Article

References (37)

1. J.M. Friedman, A war on obesity, not the obese. Science 299, 856–858 (2003)
2. Y. Matsuzawa, T. Funahashi, T. Nakamura, The concept of metabolic syndrome: contribution of visceral fat accumulation and its molecular mechanism. J. Atheroscler. Thromb. 18, 629–639 (2011)
3. N. Ouchi, J.L. Parker, J.J. Lugus, K. Walsh, Adipokines in inflammation and metabolic disease. Nat. Rev. Immunol. 11, 85–97 (2011)
4. M.C. Foster, S.J. Hwang, S.A. Porter, J.M. Massaro, U. Hoffmann, C.S. Fox, Fatty kidney, hypertension, and chronic kidney disease: the Framingham Heart Study. Hypertension 58, 784–790 (2011)
5. S. Ringholm, J. Grunnet Knudsen, L. Leick, A. Lundgaard, M. Munk Nielsen, H. Pilegaard, PGC-1alpha is required for exercise- and exercise training-induced UCP1 up-regulation in mouse white adipose tissue. PLoS One 8, e64123 (2013)
6. P. Bostrom, J. Wu, M.P. Jedrychowski, A. Korde, L. Ye, J.C. Lo, K.A. Rasbach, E.A. Bostrom, J.H. Choi, J.Z. Long, S. Kajimura, M.C. Zingaretti, B.F. Ving, H. Tu, S. Cinti, K. Hojlund, S.P. Gyqi, B.M. Spiegelman, A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature 481, 463–468 (2012)
7. P.A. Svensson, K. Lindberg, J.M. Hoffmann, M. Taube, M.J. Pereira, T. Mohsen-Kanson, A.L. Hafner, M. Rizell, J. Palming, C. Dani, M.K. Svensson, Characterization of brown adipose tissue in the human perirenal depot. Obesity 22, 1830–1837 (2014)
8. D. Ricquier, Respiration uncoupling and metabolism in the control of energy expenditure. Proc. Nutr. Soc. 64, 47–52 (2005)
9. L. Chang, L. Villacorta, R. Li, M. Hamblin, W. Xu, C. Dou, J. Zhang, J. Wu, R. Zeng, Y.E. Chen, Loss of perivascular adipose tissue on peroxisome proliferator-activated receptor-gamma deletion in smooth muscle cells impairs intravascular thermoregulation and enhances atherosclerosis. Circulation 126, 1067–1078 (2012)
10. M. Dong, X. Yang, S. Lim, Z. Cao, J. Honek, H. Lu, C. Zhang, T. Seki, K. Hosaka, E. Wahlberg, J. Yang, L. Zhang, T. Lanne, B. Sun, X. Li, Y. Liu, Y. Zhang, Y. Cao, Cold exposure promotes atherosclerotic plaque growth and instability via UCP1-dependent lipolysis. Cell Metab. 18, 118–129 (2013)
11. A.V. Chobanian, G.L. Bakris, H.R. Black, W.C. Cushman, L.A. Green, JLJr Izzo, D.W. Jones, B.J. Materson, S. Oparil, JTJr Wright, E.J. Roccella, The seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure: the JNC 7 report. JAMA 289, 2560–2572 (2003)
12. T. Montalcini, G. Gorgone, A. Fava, S. Romeo, C. Gazzaruso, A. Pujia, Carotid and brachial arterial enlargement in postmenopausal women with hypertension. Menopause 19, 145–149 (2012)
13. Z. Wu, P. Puigserver, U. Andersson, C. Zhang, G. Adelmant, V. Mootha, A. Troy, S. Cinti, B. Lowell, R.C. Scarpulla, B.M. Spiegelam, Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell 98, 115–124 (1999)
14. P. Seale, B. Bjork, W. Yang, S. Kajimura, S. Chin, S. Kuang, A. Scime, S. Devarakonda, H.M. Conroe, H. Erdjument-Bromage, P. Tempst, M.A. Rudnicki, D.R. Beier, B.M. Spiegelman, PRDM16 controls a brown fat/skeletal muscle switch. Nature 454, 961–967 (2008)
15. Z. Zhou, S. Yon Toh, Z. Chen, K. Guo, C.P. Ng, S. Ponniah, S.C. Lin, W. Hong, P. Li, Cidea-deficient mice have lean phenotype and are resistant to obesity. Nat. Genet. 35, 49–56 (2003)
16. A.M. Cypess, A.P. White, C. Vernochet, T.J. Schulz, R. Xue, C.A. Sass, T.L. Huang, C. Roberts-Toler, L.S. Weiner, C. Sze, A.T. Chacko, L.N. Deschamps, L.M. Herder, N. Truchan, A.L. Glasgow, A.R. Holman, A. Gavrila, P.O. Hasselgren, M.A. Mori, M. Molla, Y.H. Tseng, Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat. Nat. Med. 19, 635–639 (2013)
17. R. Drolet, C. Belanger, M. Fortier, C. Huot, J. Mailloux, D. Legare, A. Tchernof, Fat depot-specific impact of visceral obesity on adipocyte adiponectin release in women. Obesity 17, 424–430 (2009)
18. O. Osborn, J.M. Olefsky, The cellular and signaling networks linking the immune system and metabolism in disease. Nat. Med. 18, 363–374 (2012)
19. F. Forner, C. Kumar, C.A. Luber, T. Fromme, M. Klingenspor, M. Mann, Proteome differences between brown and white fat mitochondrial reveal specialized metabolic functions. Cell Metab. 10, 324–335 (2009)
20. S.J. Yeaman, Hormone-sensitive lipase-new roles for an old enzyme. Biochem. J. 379, 11–22 (2004)
21. J. Van de Voorde, B. Pauwels, C. Boydens, K. Decaluwe, Adipocytokines in relation to cardiovascular disease. Metabolism 62, 1513–1521 (2013)
22. K.T. Stepniakowski, T.L. Goodfriend, B.M. Egan, Fatty acids enhance vascular alpha-adrenergic sensitivity. Hypertension 25, 774–778 (1995)
23. J.E. Hall, A.A. da Silva, J.M. do Carmo, J. Dubinion, S. Hamza, S. Munusamy, G. Smith, D.E. Stec, Obesity-induced hypertension: role of sympathetic nervous system, leptin, and melanocortins. J. Biol. Chem. 285, 17271–17276 (2010)
24. D. Dicker, E. Atar, R. Kornowski, G.N. Bachar, Increased epicardial adipose tissue thickness as a predictor for hypertension: a cross-sectional observational study. J. Clin. Hypertens. 15, 893–898 (2013)
25. J. Wu, P. Bostrom, L.M. Sparks, L. Ye, J.H. Choi, A.H. Giang, M. Khandekar, K.A. Virtanen, P. Nuutila, G. Schaart, K. Huang, H. Tu, W.D. van Marken Lichtenbelt, J. Hoeks, S. Enerback, P. Schrauwen, B.M. Spiegelman, Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human. Cell 150, 366–376 (2012)
26. M.E. Lidell, M.J. Betz, O. Dahlqvist Leinhard, M. Heglind, L. Elander, M. Slawik, T. Mussack, D. Nilsson, T. Romu, P. Nuutila, K.A. Virtanen, F. Beuschlein, A. Persson, M. Borga, S. Enerback, Evidence for two types of brown adipose tissue in humans. Nat. Med. 19, 631–634 (2013)
27. C.S. Tam, V. Lecoultre, E. Ravussin, Brown adipose tissue: mechanisms and potential therapeutic targets. Circulation 125, 2782–2791 (2012)
28. K.I. Stanford, R.J. Middelbeek, K.L. Townsend, D. An, E.B. Nygaard, K.M. Hitchcox, K.R. Markan, K. Nakano, M.F. Hirshman, Y.H. Tseng, L.J. Goodyear, Brown adipose tissue regulates glucose homeostasis and insulin sensitivity. J. Clin. Invest. 123, 215–223 (2013)
29. N. Petrovic, T.B. Walden, I.G. Shabalina, J.A. Timmons, B. Cannon, J. Nedergaard, Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes. J. Biol. Chem. 285, 7153–7164 (2010)
30. M. Rosenwald, A. Perdikari, T. Rulicke, C. Wolfrum, Bi-directional interconversion of brite and white adipocytes. Nat. Cell Biol. 15, 659–667 (2013)
31. A. Gastaldelli, G. Basta, Ectopic fat and cardiovascular disease: what is the link? Nutr. Metab. Cardiovasc. Dis. 20, 481–490 (2010)
32. F. Ertas, H. Kaya, H. Acet, H. Cil, A. Akyuz, Y. Islamoglu, E. Tekbas, Z. Ariturk, M. Aydin, S. Soydinc, Increased echocardiographic epicardial fat thickness is related to impaired diurnal blood pressure profiles. Blood Press. 21, 202–208 (2012)
33. P. Lee, M.M. Swarbrick, K.K. Ho, Brown adipose tissue in adult humans: a metabolic renaissance. Endocr. Rev. 34, 413–438 (2013)
34. V. Ouellet, A. Routhier-Labadie, W. Bellemare, L. Lakhal-Chaieb, E. Turcotte, A.C. Carpentier, D. Richard, Outdoor temperature, age, sex, body mass index, and diabetic status determine the prevalence, mass, and glucose-uptake activity of 18F-FDG-detected BAT in humans. J. Clin. Endocrinol. Metab. 96, 192–199 (2011)
35. T. Szasz, R.C. Webb, Perivascular adipose tissue: more than just structural support. Clin. Sci. 122, 1–12 (2012)
36. G. Iacobellis, C. Di Gioia, L. Petramala, C. Chiappetta, V. Serra, L. Zinnamosca, C. Marinelli, A. Ciardi, G. De Toma, C. Letizia, Brown fat expresses adiponectin in humans. Int. J. Endocrinol. 2013, 126751 (2013)
37. C. Letizia, L. Petramala, C.R. Di Gioia, C. Chiappetta, L. Zinnamosca, C. Marinelli, G. Iannucci, A. Ciardi, G. De Toma, G. Iacobellis, Leptin and adiponectin mRNA expression from the adipose tissue surrounding the adrenal neoplasia. J. Clin. Endocrinol. Metab. 100, E101–E104 (2015)