-
2
-
-
0032572086
-
Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air force/texas coronary atherosclerosis prevention study
-
Downs J.R., Clearfield M., Weis S., Whitney E., Shapiro D.R., Beere P.A., Langendorfer A., Stein E.A., Kruyer W., Gotto A.M. Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air force/texas coronary atherosclerosis prevention study. J. Am. Med. Assoc. 1998, 279:1615-1622.
-
(1998)
J. Am. Med. Assoc.
, vol.279
, pp. 1615-1622
-
-
Downs, J.R.1
Clearfield, M.2
Weis, S.3
Whitney, E.4
Shapiro, D.R.5
Beere, P.A.6
Langendorfer, A.7
Stein, E.A.8
Kruyer, W.9
Gotto, A.M.10
-
3
-
-
0022549920
-
A receptor-mediated pathway for cholesterol homeostasis
-
Brown M.S., Goldstein J.L. A receptor-mediated pathway for cholesterol homeostasis. Science 1986, 232:34-47.
-
(1986)
Science
, vol.232
, pp. 34-47
-
-
Brown, M.S.1
Goldstein, J.L.2
-
4
-
-
0027078623
-
Hepatic clearance of plasma low density lipoproteins
-
Spady D.K. Hepatic clearance of plasma low density lipoproteins. Semin. Liver. Dis. 1992, 12:373-385.
-
(1992)
Semin. Liver. Dis.
, vol.12
, pp. 373-385
-
-
Spady, D.K.1
-
5
-
-
0030941803
-
The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
-
Brown M.S., Goldstein J.L. The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 1997, 89:331-340.
-
(1997)
Cell
, vol.89
, pp. 331-340
-
-
Brown, M.S.1
Goldstein, J.L.2
-
6
-
-
33750597734
-
Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice
-
Lagace T.A., Curtis D.E., Garuti R., McNutt M.C., Park S.W., Prather H.B., Anderson N.N., Ho Y.K., Hammer R.E., Horton J.D. Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice. J. Clin. Invest. 2006, 116:2995-3005.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 2995-3005
-
-
Lagace, T.A.1
Curtis, D.E.2
Garuti, R.3
McNutt, M.C.4
Park, S.W.5
Prather, H.B.6
Anderson, N.N.7
Ho, Y.K.8
Hammer, R.E.9
Horton, J.D.10
-
7
-
-
79959634407
-
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
-
Zhang L., Fairall L., Goult B.T., Calkin A.C., Hong C., Millard C.J., Tontonoz P., Schwabe J.W. The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor. Genes Dev. 2011, 25:1262-1274.
-
(2011)
Genes Dev.
, vol.25
, pp. 1262-1274
-
-
Zhang, L.1
Fairall, L.2
Goult, B.T.3
Calkin, A.C.4
Hong, C.5
Millard, C.J.6
Tontonoz, P.7
Schwabe, J.W.8
-
8
-
-
0031895061
-
Stabilization and cytoskeletal-association of LDL receptor mRNA are mediated by distinct domains in its 3' untranslated region
-
Wilson G.M., Vasa M.Z., Deeley R.G. Stabilization and cytoskeletal-association of LDL receptor mRNA are mediated by distinct domains in its 3' untranslated region. J. Lipid. Res. 1998, 39:1025-1032.
-
(1998)
J. Lipid. Res.
, vol.39
, pp. 1025-1032
-
-
Wilson, G.M.1
Vasa, M.Z.2
Deeley, R.G.3
-
9
-
-
67649729571
-
Identification of mRNA binding proteins that regulate the stability of LDL receptor mRNA through AU-rich elements
-
Li H., Chen W., Zhou Y., Abidi P., Sharpe O., Robinson W.H., Kraemer F.B., Liu J. Identification of mRNA binding proteins that regulate the stability of LDL receptor mRNA through AU-rich elements. J. Lipid. Res. 2009, 50:820-831.
-
(2009)
J. Lipid. Res.
, vol.50
, pp. 820-831
-
-
Li, H.1
Chen, W.2
Zhou, Y.3
Abidi, P.4
Sharpe, O.5
Robinson, W.H.6
Kraemer, F.B.7
Liu, J.8
-
10
-
-
84871372664
-
5-Aminoimidazole-4-carboxamide ribonucleoside stabilizes low density lipoprotein receptor mRNA in hepatocytes via ERK-dependent HuR binding to an AU-rich element
-
Yashiro T., Nanmoku M., Shimizu M., Inoue J., Sato R. 5-Aminoimidazole-4-carboxamide ribonucleoside stabilizes low density lipoprotein receptor mRNA in hepatocytes via ERK-dependent HuR binding to an AU-rich element. Atherosclerosis 2013, 226:95-101.
-
(2013)
Atherosclerosis
, vol.226
, pp. 95-101
-
-
Yashiro, T.1
Nanmoku, M.2
Shimizu, M.3
Inoue, J.4
Sato, R.5
-
11
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116:281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
12
-
-
61849137222
-
Many roads to maturity: microRNA biogenesis pathways and their regulation
-
Winter J., Jung S., Keller S., Gregory R.I., Diederichs S. Many roads to maturity: microRNA biogenesis pathways and their regulation. Nat. Cell Biol. 2009, 11:228-234.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 228-234
-
-
Winter, J.1
Jung, S.2
Keller, S.3
Gregory, R.I.4
Diederichs, S.5
-
13
-
-
42249093319
-
LNA-mediated microRNA silencing in non-human primates
-
Elmen J., Lindow M., Schutz S., Lawrence M., Petri A., Obad S., Lindholm M., Hedtjarn M., Hansen H.F., Berger U., Gullans S., Kearney P., Sarnow P., Straarup E.M., Kauppinen S. LNA-mediated microRNA silencing in non-human primates. Nature 2008, 452:896-899.
-
(2008)
Nature
, vol.452
, pp. 896-899
-
-
Elmen, J.1
Lindow, M.2
Schutz, S.3
Lawrence, M.4
Petri, A.5
Obad, S.6
Lindholm, M.7
Hedtjarn, M.8
Hansen, H.F.9
Berger, U.10
Gullans, S.11
Kearney, P.12
Sarnow, P.13
Straarup, E.M.14
Kauppinen, S.15
-
14
-
-
40249106014
-
Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver
-
Elmen J., Lindow M., Silahtaroglu A., Bak M., Christensen M., Lind-Thomsen A., Hedtjarn M., Hansen J.B., Hansen H.F., Straarup E.M., McCullagh K., Kearney P., Kauppinen S. Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver. Nucleic. Acids Res. 2008, 36:1153-1162.
-
(2008)
Nucleic. Acids Res.
, vol.36
, pp. 1153-1162
-
-
Elmen, J.1
Lindow, M.2
Silahtaroglu, A.3
Bak, M.4
Christensen, M.5
Lind-Thomsen, A.6
Hedtjarn, M.7
Hansen, J.B.8
Hansen, H.F.9
Straarup, E.M.10
McCullagh, K.11
Kearney, P.12
Kauppinen, S.13
-
15
-
-
33645075443
-
MiR-122 regulation of lipid metabolism revealed by in vivo antisense targeting
-
Esau C., Davis S., Murray S.F., Yu X.X., Pandey S.K., Pear M., Watts L., Booten S.L., Graham M., McKay R., Subramaniam A., Propp S., Lollo B.A., Freier S., Bennett C.F., Bhanot S., Monia B.P. miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting. Cell Metab. 2006, 3:87-98.
-
(2006)
Cell Metab.
, vol.3
, pp. 87-98
-
-
Esau, C.1
Davis, S.2
Murray, S.F.3
Yu, X.X.4
Pandey, S.K.5
Pear, M.6
Watts, L.7
Booten, S.L.8
Graham, M.9
McKay, R.10
Subramaniam, A.11
Propp, S.12
Lollo, B.A.13
Freier, S.14
Bennett, C.F.15
Bhanot, S.16
Monia, B.P.17
-
16
-
-
28444469246
-
Silencing of microRNAs in vivo with 'antagomirs'
-
Krutzfeldt J., Rajewsky N., Braich R., Rajeev K.G., Tuschl T., Manoharan M., Stoffel M. Silencing of microRNAs in vivo with 'antagomirs'. Nature 2005, 438:685-689.
-
(2005)
Nature
, vol.438
, pp. 685-689
-
-
Krutzfeldt, J.1
Rajewsky, N.2
Braich, R.3
Rajeev, K.G.4
Tuschl, T.5
Manoharan, M.6
Stoffel, M.7
-
17
-
-
79960015327
-
Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis
-
Rayner K.J., Sheedy F.J., Esau C.C., Hussain F.N., Temel R.E., Parathath S., van Gils J.M., Rayner A.J., Chang A.N., Suarez Y., Fernandez-Hernando C., Fisher E.A., Moore K.J. Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis. J. Clin. Invest. 2011, 121:2921-2931.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 2921-2931
-
-
Rayner, K.J.1
Sheedy, F.J.2
Esau, C.C.3
Hussain, F.N.4
Temel, R.E.5
Parathath, S.6
van Gils, J.M.7
Rayner, A.J.8
Chang, A.N.9
Suarez, Y.10
Fernandez-Hernando, C.11
Fisher, E.A.12
Moore, K.J.13
-
18
-
-
80054971110
-
Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides
-
Rayner K.J., Esau C.C., Hussain F.N., McDaniel A.L., Marshall S.M., van Gils J.M., Ray T.D., Sheedy F.J., Goedeke L., Liu X., Khatsenko O.G., Kaimal V., Lees C.J., Fernandez-Hernando C., Fisher E.A., Temel R.E., Moore K.J. Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides. Nature 2011, 478:404-407.
-
(2011)
Nature
, vol.478
, pp. 404-407
-
-
Rayner, K.J.1
Esau, C.C.2
Hussain, F.N.3
McDaniel, A.L.4
Marshall, S.M.5
van Gils, J.M.6
Ray, T.D.7
Sheedy, F.J.8
Goedeke, L.9
Liu, X.10
Khatsenko, O.G.11
Kaimal, V.12
Lees, C.J.13
Fernandez-Hernando, C.14
Fisher, E.A.15
Temel, R.E.16
Moore, K.J.17
-
19
-
-
77953787211
-
MiR-33 contributes to the regulation of cholesterol homeostasis
-
Rayner K.J., Suarez Y., Davalos A., Parathath S., Fitzgerald M.L., Tamehiro N., Fisher E.A., Moore K.J., Fernandez-Hernando C. MiR-33 contributes to the regulation of cholesterol homeostasis. Science 2010, 328:1570-1573.
-
(2010)
Science
, vol.328
, pp. 1570-1573
-
-
Rayner, K.J.1
Suarez, Y.2
Davalos, A.3
Parathath, S.4
Fitzgerald, M.L.5
Tamehiro, N.6
Fisher, E.A.7
Moore, K.J.8
Fernandez-Hernando, C.9
-
20
-
-
77953780835
-
MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis
-
Najafi-Shoushtari S.H., Kristo F., Li Y., Shioda T., Cohen D.E., Gerszten R.E., Naar A.M. MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis. Science 2010, 328:1566-1569.
-
(2010)
Science
, vol.328
, pp. 1566-1569
-
-
Najafi-Shoushtari, S.H.1
Kristo, F.2
Li, Y.3
Shioda, T.4
Cohen, D.E.5
Gerszten, R.E.6
Naar, A.M.7
-
21
-
-
77955456415
-
MiR-33 links SREBP-2 induction to repression of sterol transporters
-
Marquart T.J., Allen R.M., Ory D.S., Baldan A. miR-33 links SREBP-2 induction to repression of sterol transporters. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:12228-12232.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 12228-12232
-
-
Marquart, T.J.1
Allen, R.M.2
Ory, D.S.3
Baldan, A.4
-
22
-
-
84878967914
-
MicroRNAs 185, 96, and 223 repress selective high-density lipoprotein cholesterol uptake through posttranscriptional inhibition
-
Wang L., Jia X.J., Jiang H.J., Du Y., Yang F., Si S.Y., Hong B. MicroRNAs 185, 96, and 223 repress selective high-density lipoprotein cholesterol uptake through posttranscriptional inhibition. Mol. Cell. Biol. 2013, 33:1956-1964.
-
(2013)
Mol. Cell. Biol.
, vol.33
, pp. 1956-1964
-
-
Wang, L.1
Jia, X.J.2
Jiang, H.J.3
Du, Y.4
Yang, F.5
Si, S.Y.6
Hong, B.7
-
23
-
-
84893357948
-
Identification of miR-185 as a regulator of de novo cholesterol biosynthesis and low density lipoprotein uptake
-
Yang M., Liu W., Pellicane C., Sahyoun C., Joseph B.K., Gallo-Ebert C., Donigan M., Pandya D., Giordano C., Bata A., Nickels J.T. Identification of miR-185 as a regulator of de novo cholesterol biosynthesis and low density lipoprotein uptake. J. Lipid. Res. 2014, 55:226-238.
-
(2014)
J. Lipid. Res.
, vol.55
, pp. 226-238
-
-
Yang, M.1
Liu, W.2
Pellicane, C.3
Sahyoun, C.4
Joseph, B.K.5
Gallo-Ebert, C.6
Donigan, M.7
Pandya, D.8
Giordano, C.9
Bata, A.10
Nickels, J.T.11
-
24
-
-
84863225033
-
Salvianolic acid B inhibits macrophage uptake of modified low density lipoprotein (mLDL) in a scavenger receptor CD36-dependent manner
-
Bao Y., Wang L., Xu Y., Yang Y., Si S., Cho S., Hong B. Salvianolic acid B inhibits macrophage uptake of modified low density lipoprotein (mLDL) in a scavenger receptor CD36-dependent manner. Atherosclerosis 2012, 223:152-159.
-
(2012)
Atherosclerosis
, vol.223
, pp. 152-159
-
-
Bao, Y.1
Wang, L.2
Xu, Y.3
Yang, Y.4
Si, S.5
Cho, S.6
Hong, B.7
-
25
-
-
84655163918
-
MicroRNA-451 regulates p38 MAPK signaling by targeting of Ywhaz and suppresses the mesangial hypertrophy in early diabetic nephropathy
-
Zhang Z., Luo X., Ding S., Chen J., Chen T., Chen X., Zha H., Yao L., He X., Peng H. MicroRNA-451 regulates p38 MAPK signaling by targeting of Ywhaz and suppresses the mesangial hypertrophy in early diabetic nephropathy. Febs. Lett. 2012, 586:20-26.
-
(2012)
Febs. Lett.
, vol.586
, pp. 20-26
-
-
Zhang, Z.1
Luo, X.2
Ding, S.3
Chen, J.4
Chen, T.5
Chen, X.6
Zha, H.7
Yao, L.8
He, X.9
Peng, H.10
-
26
-
-
67349261980
-
Identification of trichostatin A as a novel transcriptional up-regulator of scavenger receptor BI both in HepG2 and RAW 264.7 cells
-
Bao Y., Yang Y., Wang L., Gao L., Jiang W., Si S., Hong B. Identification of trichostatin A as a novel transcriptional up-regulator of scavenger receptor BI both in HepG2 and RAW 264.7 cells. Atherosclerosis 2009, 204:127-135.
-
(2009)
Atherosclerosis
, vol.204
, pp. 127-135
-
-
Bao, Y.1
Yang, Y.2
Wang, L.3
Gao, L.4
Jiang, W.5
Si, S.6
Hong, B.7
-
27
-
-
84891818318
-
MiRBase: annotating high confidence microRNAs using deep sequencing data
-
Kozomara A., Griffiths-Jones S. miRBase: annotating high confidence microRNAs using deep sequencing data. Nucleic. Acids Res. 2014, 42:D68-D73.
-
(2014)
Nucleic. Acids Res.
, vol.42
, pp. D68-D73
-
-
Kozomara, A.1
Griffiths-Jones, S.2
-
28
-
-
80455154984
-
Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs
-
Garcia D.M., Baek D., Shin C., Bell G.W., Grimson A., Bartel D.P. Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs. Nat. Struct. Mol. Biol. 2011, 18:1139-1146.
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 1139-1146
-
-
Garcia, D.M.1
Baek, D.2
Shin, C.3
Bell, G.W.4
Grimson, A.5
Bartel, D.P.6
-
29
-
-
38549124383
-
The microRNA.org resource: targets and expression
-
Betel D., Wilson M., Gabow A., Marks D.S., Sander C. The microRNA.org resource: targets and expression. Nucleic. Acids. Res. 2008, 36:D149-D153.
-
(2008)
Nucleic. Acids. Res.
, vol.36
, pp. D149-D153
-
-
Betel, D.1
Wilson, M.2
Gabow, A.3
Marks, D.S.4
Sander, C.5
-
30
-
-
77955963884
-
Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites
-
Betel D., Koppal A., Agius P., Sander C., Leslie C. Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites. Genome Biol. 2010, 11:R90.
-
(2010)
Genome Biol.
, vol.11
, pp. R90
-
-
Betel, D.1
Koppal, A.2
Agius, P.3
Sander, C.4
Leslie, C.5
-
31
-
-
23744458086
-
Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes
-
Siepel A., Bejerano G., Pedersen J.S., Hinrichs A.S., Hou M., Rosenbloom K., Clawson H., Spieth J., Hillier L.W., Richards S., Weinstock G.M., Wilson R.K., Gibbs R.A., Kent W.J., Miller W., Haussler D. Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes. Genome Res. 2005, 15:1034-1050.
-
(2005)
Genome Res.
, vol.15
, pp. 1034-1050
-
-
Siepel, A.1
Bejerano, G.2
Pedersen, J.S.3
Hinrichs, A.S.4
Hou, M.5
Rosenbloom, K.6
Clawson, H.7
Spieth, J.8
Hillier, L.W.9
Richards, S.10
Weinstock, G.M.11
Wilson, R.K.12
Gibbs, R.A.13
Kent, W.J.14
Miller, W.15
Haussler, D.16
-
32
-
-
77954113554
-
Ribonucleoprotein immunoprecipitation (RNP-IP): a direct in vivo analysis of microRNA-targets
-
Hassan M.Q., Gordon J.A., Lian J.B., van Wijnen A.J., Stein J.L., Stein G.S. Ribonucleoprotein immunoprecipitation (RNP-IP): a direct in vivo analysis of microRNA-targets. J. Cell Biochem. 2010, 110:817-822.
-
(2010)
J. Cell Biochem.
, vol.110
, pp. 817-822
-
-
Hassan, M.Q.1
Gordon, J.A.2
Lian, J.B.3
van Wijnen, A.J.4
Stein, J.L.5
Stein, G.S.6
-
33
-
-
1842830455
-
SM22alpha modulates vascular smooth muscle cell phenotype during atherogenesis
-
Feil S., Hofmann F., Feil R. SM22alpha modulates vascular smooth muscle cell phenotype during atherogenesis. Circ. Res. 2004, 94:863-865.
-
(2004)
Circ. Res.
, vol.94
, pp. 863-865
-
-
Feil, S.1
Hofmann, F.2
Feil, R.3
-
35
-
-
84871404196
-
MiR-17-5p regulates endocytic trafficking through targeting TBC1D2/Armus
-
Serva A., Knapp B., Tsai Y.T., Claas C., Lisauskas T., Matula P., Harder N., Kaderali L., Rohr K., Erfle H., Eils R., Braga V., Starkuviene V. miR-17-5p regulates endocytic trafficking through targeting TBC1D2/Armus. PLoS One 2013, 7:e52555.
-
(2013)
PLoS One
, vol.7
, pp. e52555
-
-
Serva, A.1
Knapp, B.2
Tsai, Y.T.3
Claas, C.4
Lisauskas, T.5
Matula, P.6
Harder, N.7
Kaderali, L.8
Rohr, K.9
Erfle, H.10
Eils, R.11
Braga, V.12
Starkuviene, V.13
-
36
-
-
34347376692
-
Characterization of microRNA expression profiles in normal human tissues
-
Liang Y., Ridzon D., Wong L., Chen C. Characterization of microRNA expression profiles in normal human tissues. BMC Genomics 2007, 8:166.
-
(2007)
BMC Genomics
, vol.8
, pp. 166
-
-
Liang, Y.1
Ridzon, D.2
Wong, L.3
Chen, C.4
-
37
-
-
34249079154
-
Network motifs: theory and experimental approaches
-
Alon U. Network motifs: theory and experimental approaches. Nat. Rev. Genet. 2007, 8:450-461.
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 450-461
-
-
Alon, U.1
-
38
-
-
0142027814
-
Structure and function of the feed-forward loop network motif
-
Mangan S., Alon U. Structure and function of the feed-forward loop network motif. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:11980-11985.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 11980-11985
-
-
Mangan, S.1
Alon, U.2
-
39
-
-
79952302623
-
The role of incoherent microRNA-mediated feedforward loops in noise buffering
-
Osella M., Bosia C., Cora D., Caselle M. The role of incoherent microRNA-mediated feedforward loops in noise buffering. PLoS Comput. Biol. 2011, 7:e1001101.
-
(2011)
PLoS Comput. Biol.
, vol.7
, pp. e1001101
-
-
Osella, M.1
Bosia, C.2
Cora, D.3
Caselle, M.4
-
40
-
-
84865973117
-
Post-transcriptional regulatory networks play a key role in noise reduction that is conserved from micro-organisms to mammals
-
Joshi A., Beck Y., Michoel T. Post-transcriptional regulatory networks play a key role in noise reduction that is conserved from micro-organisms to mammals. FEBS J. 2012, 279:3501-3512.
-
(2012)
FEBS J.
, vol.279
, pp. 3501-3512
-
-
Joshi, A.1
Beck, Y.2
Michoel, T.3
|