MazF ribonucleases promote Mycobacterium tuberculosis drug tolerance and virulence in guinea pigs

Nature Communications

Volumn 6, Issue , 2015, Pages

  Tiwari, Prabhakar ^a   Arora, Garima ^a   Singh, Mamta ^a   Kidwai, Saqib ^a   Narayan, Om Prakash ^a   Singh, Ramandeep ^a  

^a Translational Health Science and Technology Institute   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANHYDROTETRACYCLINE; ETHAMBUTOL; GLUTATHIONE TRANSFERASE; LEVOFLOXACIN; MALTOSE BINDING PROTEIN; MESSENGER RNA; RIBONUCLEASE; RIBONUCLEASE MAZF; UNCLASSIFIED DRUG; ANTITOXIN; BACTERIAL PROTEIN; MAZF PROTEIN, MYCOBACTERIUM TUBERCULOSIS; TUBERCULOSTATIC AGENT;

BACTERIUM; DRUG; ENZYME ACTIVITY; GENE EXPRESSION; GENE TRANSFER; MUTATION; PHYSIOLOGY; PIG; TOXIN; VIRULENCE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL COUNT; BACTERIAL GENOME; BACTERIAL GROWTH; BACTERIAL LOAD; BACTERIAL VIRULENCE; BACTERIOSTASIS; BIOFILM; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG EXPOSURE; DRUG TOLERANCE; FEMALE; GROWTH INHIBITION; GUINEA PIG; HISTOPATHOLOGY; HOMOLOGOUS RECOMBINATION; HYPOXIA; IMMUNOBLOTTING; IN VITRO STUDY; LIVER GRANULOMA; LUNG GRANULOMA; MYCOBACTERIOPHAGE; MYCOBACTERIUM BOVIS BCG; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PROTEIN PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURVIVAL; UPREGULATION; ANIMAL; ANTIBIOTIC RESISTANCE; CHEMISTRY; DISEASE COURSE; DISEASE MODEL; GENETICS; KINETICS; MACROPHAGE; METABOLISM; MICROBIOLOGY; MUTATION; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; PHYSIOLOGY; POLYMERASE CHAIN REACTION; PROTEIN ANALYSIS; VIRULENCE;

BACTERIA (MICROORGANISMS); CAVIA; MYCOBACTERIUM BOVIS BCG; MYCOBACTERIUM TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS COMPLEX;

ANIMALS; ANTITOXINS; ANTITUBERCULAR AGENTS; BACTERIAL PROTEINS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DRUG RESISTANCE, BACTERIAL; DRUG TOLERANCE; ENDORIBONUCLEASES; FEMALE; GENOME, BACTERIAL; GUINEA PIGS; KINETICS; MACROPHAGES; MUTATION; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PROTEIN INTERACTION MAPPING; RIBONUCLEASES; VIRULENCE;

EID: 84945272909     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7059     Document Type: Article

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