Mycobacterial toxin MazF-mt6 inhibits translation through cleavage of 23S rRNA at the ribosomal A site

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 21, 2013, Pages 8501-8506

  Schifano, Jason M ^a   Edifor, Regina ^b   Sharp, Jared D ^a,b   Ouyang, Ming ^c   Konkimalla, Arvind ^a   Husson, Robert N ^b   Woychik, Nancy A ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c University of Louisville ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL TOXIN; COMPLEMENTARY DNA; MESSENGER RNA; MYCOBACTERIAL TOXIN MAZF MT6; RIBOSOME RECYCLING FACTOR; RIBOSOME RNA; RNA 23S; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENOME; DNA SEQUENCE; HYDROGEN BOND; MOLECULAR RECOGNITION; MYCOBACTERIUM SMEGMATIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECONDARY STRUCTURE; PROTEIN SYNTHESIS; RIBOSOME; RIBOSOME SUBUNIT; RNA CLEAVAGE; RNA SEQUENCE;

BACTERIAL PROTEINS; MYCOBACTERIUM TUBERCULOSIS; PROTEIN BIOSYNTHESIS; RIBOSOME SUBUNITS, LARGE, BACTERIAL; RIBOSOME SUBUNITS, SMALL, BACTERIAL; RNA, BACTERIAL; RNA, MESSENGER; RNA, RIBOSOMAL, 23S; RNA-BINDING PROTEINS;

EID: 84878149208     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1222031110     Document Type: Article

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