Intravitreal ciliary neurotrophic factor transiently improves cone-mediated function in a CNGB3−/− mouse model of achromatopsia

Investigative Ophthalmology and Visual Science

Volumn 56, Issue 11, 2015, Pages 6810-6822

  Marangoni, Dario ^a,c   Vijayasarathy, Camasamudram ^a   Bush, Ronald A ^a   Wei, Lisa L ^b   Wen, Rong ^d   Sieving, Paul A ^b  

^a NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

^b NATIONAL EYE INSTITUTE   (United States)

^c UNIVERSITY OF L'AQUILA   (Italy)

^d UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Achromatopsia; CNGB3; CNTF; Cone photoreceptors; Intravitreal injection

Indexed keywords

CILIARY NEUROTROPHIC FACTOR; DRUG IMPLANT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLOR BLINDNESS; ELECTRORETINOGRAPHY; FULL FIELD ELECTRORETINOGRAPHY; MOUSE; NONHUMAN; OPEN READING FRAME; PHOTOPIC FLICKER ELECTRORETINOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SEQUENCE ANALYSIS; WESTERN BLOTTING; ANIMAL; COLOR VISION DEFECTS; DISEASE MODEL; DRUG EFFECTS; DRUG IMPLANT; INTRAVITREAL DRUG ADMINISTRATION; PATHOPHYSIOLOGY; PHYSIOLOGY; RETINA CONE; TRANSGENIC MOUSE;

ANIMALS; CILIARY NEUROTROPHIC FACTOR; COLOR VISION DEFECTS; DISEASE MODELS, ANIMAL; DRUG IMPLANTS; ELECTRORETINOGRAPHY; INTRAVITREAL INJECTIONS; MICE; MICE, TRANSGENIC; RETINAL CONE PHOTORECEPTOR CELLS;

EID: 84945251429     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.15-16866     Document Type: Article

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