BDNF in Lower Brain Parts Modifies Auditory Fiber Activity to Gain Fidelity but Increases the Risk for Generation of Central Noise After Injury

Molecular Neurobiology

Volumn 53, Issue 8, 2016, Pages 5607-5627

  Chumak, Tetyana ^a   Rüttiger, Lukas ^b   Lee, Sze Chim ^b   Campanelli, Dario ^b   Zuccotti, Annalisa ^b,g   Singer, Wibke ^b   Popelář, Jiří ^a   Gutsche, Katja ^c   Geisler, Hyun Soon ^b   Schraven, Sebastian Philipp ^d   Jaumann, Mirko ^b   Panford Walsh, Rama ^e   Hu, Jing ^f   Schimmang, Thomas ^c   Zimmermann, Ulrike ^b   Syka, Josef ^a   Knipper, Marlies ^b  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Czech Republic)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^c University of Valladolid   (Spain)

^d UNIVERSITY OF WÜRZBURG   (Germany)

^e DNA Genotek Inc   (Canada)

^f UNIVERSITY OF TÜBINGEN   (Germany)

^g GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

BDNF; Central hyperactivity; High spontaneous rate, low threshold fibers; Homeostatic plasticity; Inferior colliculus; Sound detection threshold

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; PARVALBUMIN; CRE RECOMBINASE; INTEGRASE; NEUROTROPHIN 3 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUDITORY CORTEX; AUDITORY NERVOUS SYSTEM; COCHLEAR NERVE; CONTROLLED STUDY; CORTI ORGAN; EVOKED BRAIN STEM AUDITORY RESPONSE; HEARING; HEARING ACUITY; HIPPOCAMPUS; INFERIOR COLLICULUS; KNOCKOUT MOUSE; LATENT PERIOD; MOUSE; NOISE INJURY; NONHUMAN; ANIMAL; AUDITORY THRESHOLD; COCHLEA; GENE DELETION; GENETICS; METABOLISM; NOISE; PATHOLOGY; PATHOPHYSIOLOGY; PROMOTER REGION; RISK FACTOR;

ANIMALS; AUDITORY CORTEX; AUDITORY THRESHOLD; BRAIN-DERIVED NEUROTROPHIC FACTOR; COCHLEA; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; GENE DELETION; HEARING; INFERIOR COLLICULI; INTEGRASES; MICE, KNOCKOUT; NOISE; PROMOTER REGIONS, GENETIC; RECEPTOR, TRKC; RISK FACTORS;

EID: 84945219236     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-015-9474-x     Document Type: Article

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