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Volumn 6, Issue 30, 2015, Pages 28949-28960

Loss of miR-200b promotes invasion via activating the Kindlin-2/integrin β1/AKT pathway in esophageal squamous cell carcinoma: An E-cadherin-independent mechanism

Author keywords

E cadherin; Esophageal squamous cell carcinoma; Invasion; MiR 200; Prognosis

Indexed keywords

BETA1 INTEGRIN; FOCAL ADHESION KINASE; KINDLIN 2; MICRORNA 200B; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ZEB1; TRANSCRIPTION FACTOR ZEB2; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; CADHERIN; CDH1 PROTEIN, HUMAN; HOMEODOMAIN PROTEIN; MEMBRANE PROTEIN; MICRORNA; MIG2B PROTEIN, HUMAN; MIRN200 MICRORNA, HUMAN; REPRESSOR PROTEIN; TUMOR PROTEIN; ZEB1 PROTEIN, HUMAN; ZEB2 PROTEIN, HUMAN;

EID: 84945151360     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.5027     Document Type: Article
Times cited : (41)

References (42)
  • 4
    • 0033577121 scopus 로고    scopus 로고
    • Esophageal Cancers: Changing Character, Increasing Incidence
    • McCann J. Esophageal Cancers: Changing Character, Increasing Incidence. J. Natl. Cancer Inst. 1999; 91:497-498.
    • (1999) J. Natl. Cancer Inst , vol.91 , pp. 497-498
    • McCann, J.1
  • 5
    • 0037616996 scopus 로고    scopus 로고
    • SEER Cancer Statistics Review, 1973-1999
    • Bethesda, MD: National Cancer Institute2002
    • Ries LAG, Eisner MP, Kosary CL. SEER Cancer Statistics Review, 1973-1999. Bethesda, MD: National Cancer Institute2002.
    • Ries, L.A.G.1    Eisner, M.P.2    Kosary, C.L.3
  • 6
    • 0033396574 scopus 로고    scopus 로고
    • Number of lymph node metastases influences survival in patients with thoracic esophageal carcinoma: therapeutic value of radiation treatment for recurrence
    • Kimura H, Konishi K, Arakawa H, Oonishi I, Kaji M, Maeda K, Yabushita K, Tsuji M, Miwa A. Number of lymph node metastases influences survival in patients with thoracic esophageal carcinoma: therapeutic value of radiation treatment for recurrence. Dis Esophagus. 1999; 12:205-208.
    • (1999) Dis Esophagus , vol.12 , pp. 205-208
    • Kimura, H.1    Konishi, K.2    Arakawa, H.3    Oonishi, I.4    Kaji, M.5    Maeda, K.6    Yabushita, K.7    Tsuji, M.8    Miwa, A.9
  • 7
    • 84903710564 scopus 로고    scopus 로고
    • A family of pleiotropically acting microRNAs in cancer progression, miR-200: potential cancer therapeutic targets
    • Zhang HF, Xu LY, Li EM. A family of pleiotropically acting microRNAs in cancer progression, miR-200: potential cancer therapeutic targets. Curr Pharm Des. 2014; 20:1896-1903.
    • (2014) Curr Pharm Des , vol.20 , pp. 1896-1903
    • Zhang, H.F.1    Xu, L.Y.2    Li, E.M.3
  • 8
    • 70450263322 scopus 로고    scopus 로고
    • The miR200 family of microRNAs regulates WAVE3-dependent cancer cell invasion
    • Sossey-Alaoui K, Bialkowska K, Plow EF. The miR200 family of microRNAs regulates WAVE3-dependent cancer cell invasion. J Biol Chem. 2009; 284:33019-33029.
    • (2009) J Biol Chem , vol.284 , pp. 33019-33029
    • Sossey-Alaoui, K.1    Bialkowska, K.2    Plow, E.F.3
  • 13
    • 41649091906 scopus 로고    scopus 로고
    • The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
    • Park SM, Gaur AB, Lengyel E, Peter ME. The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev. 2008; 22:894-907.
    • (2008) Genes Dev , vol.22 , pp. 894-907
    • Park, S.M.1    Gaur, A.B.2    Lengyel, E.3    Peter, M.E.4
  • 15
    • 84883894502 scopus 로고    scopus 로고
    • Down-regulated desmocollin-2 promotes cell aggressiveness through redistributing adherens junctions and activating beta-catenin signalling in oesophageal squamous cell carcinoma
    • Fang WK, Liao LD, Li LY, Xie YM, Xu XE, Zhao WJ, Wu JY, Zhu MX, Wu ZY, Du ZP, Wu BL, Xie D, Guo MZ, et al. Down-regulated desmocollin-2 promotes cell aggressiveness through redistributing adherens junctions and activating beta-catenin signalling in oesophageal squamous cell carcinoma. J Pathol. 2013; 231:257-270.
    • (2013) J Pathol , vol.231 , pp. 257-270
    • Fang, W.K.1    Liao, L.D.2    Li, L.Y.3    Xie, Y.M.4    Xu, X.E.5    Zhao, W.J.6    Wu, J.Y.7    Zhu, M.X.8    Wu, Z.Y.9    Du, Z.P.10    Wu, B.L.11    Xie, D.12    Guo, M.Z.13
  • 16
    • 3042766369 scopus 로고    scopus 로고
    • E-cadherin expression in patients with esophageal squamous cell carcinoma: promoter hypermethylation, Snail overexpression, and clinicopathologic implications
    • Takeno S, Noguchi T, Fumoto S, Kimura Y, Shibata T, Kawahara K. E-cadherin expression in patients with esophageal squamous cell carcinoma: promoter hypermethylation, Snail overexpression, and clinicopathologic implications. Am J Clin Pathol. 2004; 122:78-84.
    • (2004) Am J Clin Pathol , vol.122 , pp. 78-84
    • Takeno, S.1    Noguchi, T.2    Fumoto, S.3    Kimura, Y.4    Shibata, T.5    Kawahara, K.6
  • 17
    • 77952424612 scopus 로고    scopus 로고
    • Genetic alterations in a telomerase-immortalized human esophageal epithelial cell line: implications for carcinogenesis
    • Cheung PY, Deng W, Man C, Tse WW, Srivastava G, Law S, Tsao SW, Cheung AL. Genetic alterations in a telomerase-immortalized human esophageal epithelial cell line: implications for carcinogenesis. Cancer Lett. 2010; 293:41-51.
    • (2010) Cancer Lett , vol.293 , pp. 41-51
    • Cheung, P.Y.1    Deng, W.2    Man, C.3    Tse, W.W.4    Srivastava, G.5    Law, S.6    Tsao, S.W.7    Cheung, A.L.8
  • 18
    • 0031459917 scopus 로고    scopus 로고
    • Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K
    • Keely PJ, Westwick JK, Whitehead IP, Der CJ, Parise LV. Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K. Nature. 1997; 390:632-636.
    • (1997) Nature , vol.390 , pp. 632-636
    • Keely, P.J.1    Westwick, J.K.2    Whitehead, I.P.3    Der, C.J.4    Parise, L.V.5
  • 19
    • 18844363699 scopus 로고    scopus 로고
    • ILK mediates actin filament rearrangements and cell migration and invasion through PI3K/Akt/Rac1 signaling
    • Qian Y, Zhong X, Flynn DC, Zheng JZ, Qiao M, Wu C, Dedhar S, Shi X, Jiang BH. ILK mediates actin filament rearrangements and cell migration and invasion through PI3K/Akt/Rac1 signaling. Oncogene. 2005; 24:3154-3165.
    • (2005) Oncogene , vol.24 , pp. 3154-3165
    • Qian, Y.1    Zhong, X.2    Flynn, D.C.3    Zheng, J.Z.4    Qiao, M.5    Wu, C.6    Dedhar, S.7    Shi, X.8    Jiang, B.H.9
  • 22
    • 0038719715 scopus 로고    scopus 로고
    • Specific beta1 integrin site selectively regulates Akt/protein kinase B signaling via local activation of protein phosphatase 2A
    • Pankov R, Cukierman E, Clark K, Matsumoto K, Hahn C, Poulin B, Yamada KM. Specific beta1 integrin site selectively regulates Akt/protein kinase B signaling via local activation of protein phosphatase 2A. J Biol Chem. 2003; 278:18671-18681.
    • (2003) J Biol Chem , vol.278 , pp. 18671-18681
    • Pankov, R.1    Cukierman, E.2    Clark, K.3    Matsumoto, K.4    Hahn, C.5    Poulin, B.6    Yamada, K.M.7
  • 23
    • 11344254134 scopus 로고    scopus 로고
    • beta1-integrins induce phosphorylation of Akt on serine 473 independently of focal adhesion kinase and Src family kinases
    • Velling T, Nilsson S, Stefansson A, Johansson S. beta1-integrins induce phosphorylation of Akt on serine 473 independently of focal adhesion kinase and Src family kinases. EMBO Rep. 2004; 5:901-905.
    • (2004) EMBO Rep , vol.5 , pp. 901-905
    • Velling, T.1    Nilsson, S.2    Stefansson, A.3    Johansson, S.4
  • 28
    • 34247468876 scopus 로고    scopus 로고
    • Regulation of the actin cytoskeleton in cancer cell migration and invasion
    • Yamaguchi H, Condeelis J. Regulation of the actin cytoskeleton in cancer cell migration and invasion. Biochim Biophys Acta. 2007; 1773:642-652.
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 642-652
    • Yamaguchi, H.1    Condeelis, J.2
  • 29
    • 65349132693 scopus 로고    scopus 로고
    • EMT, the cytoskeleton, and cancer cell invasion
    • Yilmaz M, Christofori G. EMT, the cytoskeleton, and cancer cell invasion. Cancer Metastasis Rev. 2009; 28:15-33.
    • (2009) Cancer Metastasis Rev , vol.28 , pp. 15-33
    • Yilmaz, M.1    Christofori, G.2
  • 30
    • 33645758275 scopus 로고    scopus 로고
    • Tumor invasion in the absence of epithelialmesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton
    • Wicki A, Lehembre F, Wick N, Hantusch B, Kerjaschki D, Christofori G. Tumor invasion in the absence of epithelialmesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton. Cancer Cell. 2006; 9:261-272.
    • (2006) Cancer Cell , vol.9 , pp. 261-272
    • Wicki, A.1    Lehembre, F.2    Wick, N.3    Hantusch, B.4    Kerjaschki, D.5    Christofori, G.6
  • 31
    • 84934435197 scopus 로고    scopus 로고
    • Kindlin-2 phosphorylation by Src at Y193 enhances Src activity and is involved in Migfilin recruitment to the focal adhesions
    • Liu Z, Lu D, Wang X, Wan J, Liu C, Zhang H. Kindlin-2 phosphorylation by Src at Y193 enhances Src activity and is involved in Migfilin recruitment to the focal adhesions. FEBS Lett. 2015; 589:2001-2010.
    • (2015) FEBS Lett , vol.589 , pp. 2001-2010
    • Liu, Z.1    Lu, D.2    Wang, X.3    Wan, J.4    Liu, C.5    Zhang, H.6
  • 32
    • 84926123925 scopus 로고    scopus 로고
    • Kindlin-2 interacts with and stabilizes EGFR and is required for EGF-induced breast cancer cell migration
    • Guo B, Gao J, Zhan J, Zhang H. Kindlin-2 interacts with and stabilizes EGFR and is required for EGF-induced breast cancer cell migration. Cancer Lett. 2015; 361:271-281.
    • (2015) Cancer Lett , vol.361 , pp. 271-281
    • Guo, B.1    Gao, J.2    Zhan, J.3    Zhang, H.4
  • 33
    • 70350704818 scopus 로고    scopus 로고
    • Id-1 promotes tumorigenicity and metastasis of human esophageal cancer cells through activation of PI3K/AKT signaling pathway
    • Li B, Tsao SW, Li YY, Wang X, Ling MT, Wong YC, He QY, Cheung AL. Id-1 promotes tumorigenicity and metastasis of human esophageal cancer cells through activation of PI3K/AKT signaling pathway. Int J Cancer. 2009; 125:2576-2585.
    • (2009) Int J Cancer , vol.125 , pp. 2576-2585
    • Li, B.1    Tsao, S.W.2    Li, Y.Y.3    Wang, X.4    Ling, M.T.5    Wong, Y.C.6    He, Q.Y.7    Cheung, A.L.8
  • 34
    • 84964313112 scopus 로고    scopus 로고
    • Suppression of esophageal tumor growth and chemoresistance by directly targeting the PI3K/AKT pathway
    • Li B, Li J, Xu WW, Guan XY, Qin YR, Zhang LY, Law S, Tsao SW, Cheung AL. Suppression of esophageal tumor growth and chemoresistance by directly targeting the PI3K/AKT pathway. Oncotarget. 2014; 5:11576-11587.
    • (2014) Oncotarget , vol.5 , pp. 11576-11587
    • Li, B.1    Li, J.2    Xu, W.W.3    Guan, X.Y.4    Qin, Y.R.5    Zhang, L.Y.6    Law, S.7    Tsao, S.W.8    Cheung, A.L.9
  • 35
    • 84903598614 scopus 로고    scopus 로고
    • Akt-mediated transforming growth factor-β1-induced epithelial-mesenchymal transition in cultured human esophageal squamous cancer cells
    • Xuan X, Zeng Q, Li Y, Gao Y, Wang F, Zhang H, Wang Z, He H, Li S. Akt-mediated transforming growth factor-β1-induced epithelial-mesenchymal transition in cultured human esophageal squamous cancer cells. Cancer Gene Ther. 2014; 21:238-245.
    • (2014) Cancer Gene Ther , vol.21 , pp. 238-245
    • Xuan, X.1    Zeng, Q.2    Li, Y.3    Gao, Y.4    Wang, F.5    Zhang, H.6    Wang, Z.7    He, H.8    Li, S.9
  • 36
    • 84861117630 scopus 로고    scopus 로고
    • Overexpression of Aurora-A enhances invasion and matrix metalloproteinase-2 expression in esophageal squamous cell carcinoma cells
    • Wang X, Lu N, Niu B, Chen X, Xie J, Cheng N. Overexpression of Aurora-A enhances invasion and matrix metalloproteinase-2 expression in esophageal squamous cell carcinoma cells. Mol Cancer Res. 2012; 10:588-596.
    • (2012) Mol Cancer Res , vol.10 , pp. 588-596
    • Wang, X.1    Lu, N.2    Niu, B.3    Chen, X.4    Xie, J.5    Cheng, N.6
  • 37
    • 72949119124 scopus 로고    scopus 로고
    • integrins in cancer: biological implications and therapeutic opportunities
    • Desgrosellier JS, Cheresh DA. integrins in cancer: biological implications and therapeutic opportunities. Nat Rev Cancer. 2010; 10:9-22.
    • (2010) Nat Rev Cancer , vol.10 , pp. 9-22
    • Desgrosellier, J.S.1    Cheresh, D.A.2
  • 38
    • 82555189403 scopus 로고    scopus 로고
    • β1-integrin: a potential therapeutic target in the battle against cancer recurrence
    • Barkan D, Chambers AF. β1-integrin: a potential therapeutic target in the battle against cancer recurrence. Clin Cancer Res. 2011; 17:7219-7223.
    • (2011) Clin Cancer Res , vol.17 , pp. 7219-7223
    • Barkan, D.1    Chambers, A.F.2
  • 41
    • 44449178868 scopus 로고    scopus 로고
    • Rho GTPases in cancer cell biology
    • Vega FM, Ridley AJ. Rho GTPases in cancer cell biology. FEBS Lett. 2008; 582:2093-101.
    • (2008) FEBS Lett , vol.582 , pp. 2093-2101
    • Vega, F.M.1    Ridley, A.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.