Novel nanostructured lipid carrier-based inserts for controlled ocular drug delivery: Evaluation of corneal bioavailability and treatment efficacy in bacterial keratitis

Expert Opinion on Drug Delivery

Volumn 12, Issue 11, 2015, Pages 1791-1807

  Üstündaʇ Okur, Neslihan ^a   Gökçe, Evren Homan ^a   Bozbiyik, Duygu Inci ^b   Eʇrilmez, Sait ^c   Ertan, Gökhan ^a   Özer, Özgen ^a  

^a EGE UNIVERSITY   (Turkey)

^b Department of Cardiology   (Turkey)

^c EGE UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

Author keywords

chitosan oligosaccharide lactate; insert; nanoparticle; nanostructured lipid carrier; ocular; ofloxacin

Indexed keywords

CHITOSAN; CHITOSAN OLIGOSACCHARIDE LACTATE; DRUG CARRIER; GLYCEROL; LACTIC ACID; LIPID; MACROGOL 400; NANOMATERIAL; NANOSTRUCTURED LIPID CARRIER; OFLOXACIN; OLIGOSACCHARIDE; PLASTICIZER; SOLVENT; UNCLASSIFIED DRUG; EXCIPIENT; MACROGOL DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; BACTERIAL KERATITIS; CONTROLLED STUDY; CORNEA OPACITY; DIFFUSION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG STABILITY; EVAPORATION; EX VIVO STUDY; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PARTICLE SIZE; REVIEW; STAPHYLOCOCCUS AUREUS; SWELLING; ZETA POTENTIAL; ANIMAL; BIOAVAILABILITY; CHEMISTRY; CORNEA; DRUG EFFECTS; EYE INFECTIONS, BACTERIAL; KERATITIS; METABOLISM; RABBIT; TREATMENT OUTCOME;

ANIMALS; BIOLOGICAL AVAILABILITY; CORNEA; DRUG DELIVERY SYSTEMS; EXCIPIENTS; EYE INFECTIONS, BACTERIAL; KERATITIS; LIPIDS; NANOSTRUCTURES; OFLOXACIN; POLYETHYLENE GLYCOLS; RABBITS; STAPHYLOCOCCUS AUREUS; TREATMENT OUTCOME;

EID: 84945127662     PISSN: 17425247     EISSN: 17447593     Source Type: Journal    
DOI: 10.1517/17425247.2015.1059419     Document Type: Review

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