MR-guided transcranial focused ultrasound

Advances in Experimental Medicine and Biology

Volumn 880, Issue , 2016, Pages 97-111

  Aubry, Jean François ^a,b   Tanter, Mickael ^a  

^a INSTITUT LANGEVIN   (France)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

BBB opening; Mechanical ablation; Neuromodulation; Skull aberration; Thalomotomy

Indexed keywords

BLOOD BRAIN BARRIER; ESSENTIAL TREMOR; HEATING; HIGH INTENSITY FOCUSED ULTRASOUND; HUMAN; MINIMALLY INVASIVE SURGERY; NEUROMODULATION; NEUROPATHIC PAIN; NON INVASIVE PROCEDURE; NUCLEAR MAGNETIC RESONANCE IMAGING; OPTIC NERVE DISEASE; PRIORITY JOURNAL; RADIOFREQUENCY; SKULL; THALAMOTOMY; THALAMUS; TRANSCRANIAL DIRECT CURRENT STIMULATION; TRANSCRANIAL MAGNETIC RESONANCE GUIDED FOCUSED ULTRASOUND SURGERY; TRANSCRANIAL MAGNETIC STIMULATION; ULTRASOUND SURGERY; ULTRASOUND THERAPY; INTERVENTIONAL MAGNETIC RESONANCE IMAGING; PATHOLOGY; PROCEDURES; SURGERY;

HIGH-INTENSITY FOCUSED ULTRASOUND ABLATION; HUMANS; MAGNETIC RESONANCE IMAGING, INTERVENTIONAL; SKULL; THALAMUS;

EID: 84944938012     PISSN: 00652598     EISSN: 22148019     Source Type: Book Series    
DOI: 10.1007/978-3-319-22536-4_6     Document Type: Chapter

References (90)

1. Alkins R, Huang Y, Pajek D, Hynynen K (2013) Cavitation-based third ventriculostomy using MRIguided focused ultrasound: Laboratory investigation. J Neurosurg 119:1520-1529
2. Aubry JF, Tanter M, Gerber J, Thomas JL, Fink M (2001) Optimal focusing by spatio-temporal inverse fi lter. II experiments application to focusing through absorbing and reverberating media. J Acoust Soc Am 110:48-58
3. Aubry JF, Tanter M, Pernot M, Thomas JL, Fink M (2003) Experimental demonstration of noninvasive transskull adaptive focusing based on prior computed tomography scans. J Acoust Soc Am 113:84-93
4. Baron C, Aubry JF, Tanter M, Meairs S, Fink M (2009) Simulation of intracranial acoustic fi elds in clinical trials of sonothrombolysis. Ultrasound Med Biol 35:1148-1158
5. Borrelli M, Bailey K, Dunn F (1981) Early ultrasonic effects upon mammalian CNS structures (chemical synapses). J Acoust Soc Am 69:1514-1516
6. Chang WS, Jung HH, Kweon EJ, Zadicario E, Rachmilevitch I, Chang JW (2014) Unilateral magnetic resonance guided focused ultrasound thalamotomy for essential tremor: practices and clinicoradiological outcomes. J Neurol Neurosurg Psychiatry 86(3):257
7. Chauvet D, Marsac L, Pernot M, Boch AL, Guillevin R, Salameh N, Souris L, Darrasse L, Fink M, Tanter M, Aubry JF (2013) Targeting accuracy of transcranial magnetic resonance-guided high-intensity focused ultrasound brain therapy: a fresh cadaver model. J Neurosurg 118:1046-1052
8. Chen PY, Liu HL, Hua MY, Yang HW, Huang CY, Chu PC, Lyu LA, Tseng IC, Feng LY, Tsai HC, Chen SM, Lu YJ, Wang JJ, Yen TC, Ma YH, Wu T, Chen JP, Chuang JI, Shin JW, Hsueh C, Wei KC (2010) Novel magnetic/ultrasound focusing system enhances nanoparticle drug delivery for glioma treatment. Neuro Oncol 12:1050-1060
9. Choi JJ, Pernot M, Small SA, Konofagou EE (2007) Noninvasive, transcranial and localized opening of theblood-brain barrier using focused ultrasound in mice. Ultrasound Med Biol 33:95-104
10. Clark JM, White DN, Curry GR, Stevenson RJ, Campbell JK, Jenkins CO (1971) The measurement of intracranial echo pulsations. Med Biol Eng 9:263-287
11. Clement G, Hynynen K (2002a) A non-invasive method for focusing ultrasound through the human skull. Phys Med Biol 47:1219-1236
12. Clement GT, Hynynen K (2002b) Micro-receiver guided transcranial beam steering. IEEE Trans Ultrason Ferroelect Freq Control 49:447-453
13. Clement GT, Sun J, Giesecke T, Hynynen K (2000) A hemisphere array for non-invasive ultrasound brain therapy and surgery. Phys Med Biol 45:3707-3719
14. Daffertshofer M, Gass A, Ringleb P, Sitzer M, Sliwka U, Els T, Sedlaczek O, Koroshetz WJ, Hennerici MG (2005) Transcranial low-frequency ultrasoundmediated thrombolysis in brain ischemia: increased risk of hemorrhage with combined ultrasound and tissue plasminogen activator: results of a phase II clinical trial. Stroke 36:1441-1446
15. Deffi eux T, Younan Y, Wattiez N, Tanter M, Pouget P, Aubry JF (2013) Low-intensity focused ultrasound modulates monkey visuomotor behavior. Curr Biol 23:2430-2433
16. Elias WJ, Huss D, Voss T, Loomba J, Khaled M, Zadicario E, Frysinger RC, Sperling SA, Wylie S, Monteith SJ, Druzgal J, Shah BB, Harrison M, Wintermark M (2013a) A pilot study of focused ultrasound thalamotomy for essential tremor. N Engl J Med 369:640-648
17. Elias WJ, Khaled M, Hilliard JD, Aubry JF, Frysinger RC, Sheehan JP, Wintermark M, Lopes MB (2013b) A magnetic resonance imaging, histological, and dose modeling comparison of focused ultrasound, radiofrequency, and Gamma Knife radiosurgery lesions in swine thalamus. J Neurosurg 119:307-317
18. Fry FJ, Barger JE (1978) Acoustical properties of the human skull. J Acoust Soc Am 63:1576-1590
19. Fry FJ, Ades HW, Fry WJ (1958) Production of reversible changes in the central nervous system by ultrasound. Science 127:83-84
20. Fry FJ, Sanghvi NT, Foster RS, Bihrle R, Hennige C (1995) Ultrasound and microbubbles: their generation, detection and potential utilization in tissue and organ therapy—experimental. Ultrasound Med Biol 21: 1227-1237
21. Gateau J, Marsac L, Pernot M, Aubry JF, Tanter M, Fink M (2010) Transcranial ultrasonic therapy based on time reversal of acoustically induced cavitation bubble signature. IEEE Trans Biomed Eng 57:134-144
22. Gateau J, Aubry JF, Pernot M, Fink M, Tanter M (2011a) Combined passive detection and ultrafast active imaging of cavitation events induced by short pulses of high-intensity ultrasound. IEEE Trans Ultrason Ferroelectr Freq Control 58:517-532
23. Gateau J, Aubry JF, Chauvet D, Boch A, Fink M, Tanter M (2011b) In vivo bubble nucleation probability in sheep brain tissue. Phys Med Biol 56:7001
24. Gavrilov L, Gersuni G, Ilyinsky O, Sirotyuk M, Tsirulnikov E, Shchekanov E (1976) The effect offocused ultrasound on the skin and deep nerve structures of man and animal. Prog Brain Res 43:279-292
25. Gyongy M, Coussios CC (2009) Passive spatial mapping of inertial cavitation during HIFU exposure. IEEE Trans Biomed Eng 57:48-56
26. Hallett M (2000) Transcranial magnetic stimulation and the human brain. Nature 406:147-150
27. Herbert E, Pernot M, Montaldo G, Fink M, Tanter M (2009) Energy-based adaptive focusing of waves: application to noninvasive aberration correction of ultrasonic wavefi elds. IEEE Trans Ultrason Ferroelectr Freq Control 56:2388-2399
28. Hertzberg Y, Volovick A, Zur Y, Medan Y, Vitek S, Navon G (2010) Ultrasound focusing using magnetic resonance acoustic radiation force imaging: application to ultrasound transcranial therapy. Med Phys 37:2934-2942
29. Hynynen K, McDannold N, Vykhodtseva N, Jolesz FA (2001) Noninvasive MR imaging-guided focal opening of the blood-brain barrier in rabbits. Radiology 220:640-646
30. Hynynen K, McDannold N, Sheikov NA, Jolesz FA, Vykhodtseva N (2005) Local and reversible blood-brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonications. Neuroimage 24:12-20
31. Jeanmonod D, Magnin M, Morel A, Siegemund M (2001) Surgical control of the human thalamocortical dysrhythmia: I. Central lateral thalamotomy in neurogenic pain. Thalamus Relat Syst 1:71-79
32. Jeanmonod D, Werner B, Morel A, Michels L, Zadicario E, Schiff G, Martin E (2012) Transcranial magnetic resonance inaging-guided focused ultrasound: noninvasive central lateral thalamotomy for chronic neuropathic pain. Neurosurg Focus 32:1-11
33. Jenkins CO, White DN (1972) The rise time of intracranial echo pulsations and intracranial pressure. Acta Neurol Scand 48:115-123
34. Jordao JF, Ayala-Grosso CA, Markham K, Huang Y, Chopra R, McLaurin J, Hynynen K, Aubert I (2010) Antibodies targeted to the brain with image-guided focused ultrasound reduces amyloid-beta plaque load in the TgCRND8 mouse model of Alzheimer’s disease. PLoS One 5, e10549
35. Kaye EA, Chen J, Pauly KB (2011) Rapid MR‐ARFI method for focal spot localization during focused ultrasound therapy. Mag Reson Med 65:738-743
36. Kieran K, Hall TL, Parsons JE, Wolf JS, Fowlkes JB, Cain CA, Roberts WW (2007) Refi ning histotripsy: defi ning the parameter space for the creation of nonthermal lesions with high intensity, pulsed focused ultrasound of the in vitro kidney. J Urol 178:672-676
37. King RL, Brown JR, Newsome WT, Pauly KB (2013) Effective parameters for ultrasound-induced in vivo neurostimulation. Ultrasound Med Biol 39:312-331
38. Krasovitski B, Frenkel V, Shoham S, Kimmel E (2011) Intramembrane cavitation as a unifying mechanism for ultrasound-induced bioeffects. Proc Natl Acad Sci U S A 108:3258-3263
39. Larrat B, Pernot M, Montaldo G, Fink M, Tanter M (2010) MR-guided adaptive focusing of ultrasound. IEEETrans Ultrason Ferroelectr Freq Control 57: 1734-1747
40. Legon W, Sato TF, Opitz A, Mueller J, Barbour A, Williams A, Tyler WJ (2014) Transcranial focused ultrasound modulates the activity of primary somatosensory cortex in humans. Nat Neurosci 17:322-329
41. Leighton T (1994) The acoustic bubble. Academic, London
42. Lipsman N, Schwartz ML, Huang Y, Lee L, Sankar T, Chapman M, Hynynen K, Lozano AM (2013) MR-guided focused ultrasound thalamotomy for essential tremor: a proof-of-concept study. Lancet Neurol 12:462-468
43. Liu HL, Hua MY, Chen PY, Chu PC, Pan CH, Yang HW, Huang CY, Wang JJ, Yen TC, Wei KC (2010) Blood-brain barrier disruption with focused ultrasound enhances delivery of chemotherapeutic drugs for glioblastoma treatment. Radiology 255:415-425
44. Marquet F, Pernot M, Aubry JF, Montaldo G, Tanter M, Fink M (2006) Non-invasive transcranial ultrasound therapy guided by CT-scans. Conf Proc IEEE Eng Med Biol Soc 1:683-687
45. Marquet F, Boch AL, Pernot M, Montaldo G, Seilhean D, Fink M, Tanter M, Aubry JF (2013) Non-invasive ultrasonic surgery of the brain in non-human primates. J Acoust Soc Am 134:1632-1639
46. Marsac L, Chauvet D, Larrat B, Pernot M, Robert B, Fink M, Boch AL, Aubry JF, Tanter M (2012) MR-guided adaptive focusing of therapeutic ultrasound beams in the human head. Med Phys 39:1141
47. Martin E, Jeanmonod D, Morel A, Zadicario E, Werner B (2009) High-intensity focused ultrasound for noninvasive functional neurosurgery. Ann Neurol 66:858-861
48. Marty B, Larrat B, Van Landeghern M, Robic C, Robert P, Port M, Le Bihan D, Pernot M, Tanter M, Lethimonnier F, Meriaux S (2012) Dynamic study of blood-brain barrier closure after its disruption using ultrasound: a quantitative analysis. J Cereb Blood Flow Metab 32: 1948-1958
49. Monteith S, Sheehan J, Medel R, Wintermark M, Eames M, Snell J, Kassell NF, Elias WJ (2013a) Potential intracranial applications of magnetic resonance-guided focused ultrasound surgery: a review. J Neurosurg 118: 215-221
50. Monteith SJ, Harnof S, Medel R, Popp B, Wintermark M, Lopes MBS, Kassell NF, Elias WJ, Snell J, Eames M (2013b) Minimally invasive treatment of intracerebral hemorrhage with magnetic resonance-guided focused ultrasound: laboratory investigation. J Neurosurg 118: 1035-1045
51. Moser D, Zadicario E, Schiff G, Jeanmonod D (2012) Measurement of targeting accuracy in focused ultrasound functional neurosurgery: technical note. Neurosurg Focus 32, E2
52. Nitsche MA, Cohen LG, Wassermann EM, Priori A, Lang N, Antal A, Paulus W, Hummel F, Boggio PS, Fregni F (2008) Transcranial direct current stimulation: state of the art 2008. Brain Stimul 1:206-223
53. O’Reilly MA, Hynynen K (2012) Blood-brain barrier: real-time feedback-controlled focused ultrasound disruption by using an acoustic emissions-based controller. Radiology 263:96-106
54. O’Reilly MA, Waspe AC, Ganguly M, Hynynen K (2011) Focused-ultrasound disruption of the blood-brain barrier using closely-timed short pulses: infl uence of sonication parameters and injection rate. Ultrasound Med Biol 37:587-594
55. Pernot M, Aubry JF, Tanter M, Thomas J, Fink M (2003) High power transcranial beam steering for ultrasonic brain therapy. Phys Med Biol 48:2577-2589
56. Pernot M, Aubry JF, Tanter M, Boch AL, Kujas M and Fink M (2004) Ultrasonic transcranial brain therapy: First in vivo clinical investigation on 22 sheep using adaptive focusing. 2004 IEEE Ultrasonics Symposium, Vol 1-3. M. P. Yuhas, pp 1013-1016
57. Pernot M, Aubry JF, Tanter M, Boch AL, Marquet F, Kujas M, Seilhean D, Fink M (2007) In vivo transcranial brain surgery with an ultrasonic time reversal mirror. J Neurosurg 106:1061-1066
58. Phillips DJ, Smith SW, von Ramm OT and Thurstone FL (1975) Sampled aperture techniques applied to B-Mode echoencephalography. Acoustical Holography. N. Booth, Springer US, pp 103-120
59. Pinton GF, Aubry JF, Fink M and Tanter M (2010) Numerical prediction of frequency dependent 3D maps of mechanical index thresholds in ultrasonic brain therapy. Ultrasonics Symposium (IUS), 2010 IEEE
60. Pinton G, Aubry JF, Bossy E, Muller M, Pernot M, Tanter M (2012a) Attenuation, scattering, and absorption of ultrasound in the skull bone. Med Phys 39:299-307
61. Pinton G, Aubry JF, Fink M, Tanter M (2012b) Numerical prediction of frequency dependent 3D maps of mechanical index thresholds in ultrasonic brain therapy. Med Phys 39:455-467
62. Plaksin M, Shoham S, Kimmel E (2014) Intramembrane cavitation as a predictive Bio-piezoelectric mechanism for ultrasonic brain stimulation. Phys Rev X 4:011004
63. Pulkkinen A, Huang Y, Song J, Hynynen K (2011) Simulations and measurements of transcranial lowfrequency ultrasound therapy: skull-base heating and effective area of treatment. Phys Med Biol 56:4661
64. Raymond SB, Treat LH, Dewey JD, McDannold NJ, Hynynen K, Bacskai BJ (2008) Ultrasound enhanced delivery of molecular imaging and therapeutic agents in Alzheimer’s disease mouse models. PLoS One 3, e2175
65. Ressler KJ, Mayberg HS (2007) Targeting abnormal neural circuits in mood and anxiety disorders: from the laboratory to the clinic. Nature Neuroscience 10: 1116-1124
66. Sheikov N, McDannold N, Sharma S, Hynynen K (2008) Effect of focused ultrasound applied with an ultrasound contrast agent on the tight junctional integrity of the brain microvascular endothelium. Ultrasound Med Biol 34:1093-1104
67. Sun J, Hynynen K (1998) Focusing of therapeutic ultrasound through a human skull: a numerical study. J Acoust Soc Am 104:1705-1715
68. Szobota S, Gorostiza P, Del Bene F, Wyart C, Fortin DL, Kolstad KD, Tulyathan O, Volgraf M, Numano R, Aaron HL (2007) Remote control of neuronal activity with a light-gated glutamate receptor. Neuron 54: 535-545
69. Tanter M, Thomas JL and Fink M (1996) Focusing through skull with time reversal mirrors. Application to hyperthermia. 1996 IEEE Ultrasonics Symposium, Proceedings, Vols 1 and 2. Levy M, Schneider SC and McAvoy BR, pp 1289-1293
70. Tanter M, Thomas JL, Fink M (1998) Focusing and steering through absorbing and aberrating layers: application to ultrasonic propagation through the skull. J Acoust Soc Am 103:2403-2410
71. Tanter M, Thomas JL, Fink M (2000) Time reversal and the inverse fi lter. J Acoust Soc Am 108:223-234
72. Tanter M, Aubry JF, Gerber J, Thomas JL, Fink M (2001) Optimal focusing by spatio-temporal inverse fi lter I. Basic principles. J Acoust Soc Am 110:37-47
73. Tanter M, Pernot M, Aubry JF, Montaldo G, Marquet F, Fink M (2007) Compensating for bone interfaces and respiratory motion in high-intensity focused ultrasound. Int J Hyperthermia 23:141-151
74. Tasker RR (1998) Deep brain stimulation is preferable to thalamotomy for tremor suppression. Surg Neurol 49:145-153; discussion 153-144
75. Thomas JL, Fink MA (1996) Ultrasonic beam focusing through tissue inhomogeneities with a time reversal mirror: application to transskull therapy. IEEE Trans Ultrason Ferroelectr Freq Contr 43:1122-1129
76. Treat LH, McDannold N, Vykhodtseva N, Zhang Y, Tam K, Hynynen K (2007) Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRI-guided focused ultrasound. Int J Cancer 121:901-907
77. Tufail Y, Matyushov A, Baldwin N, Tauchmann ML, Georges J, Yoshihiro A, Sih T, Tyler WJ (2010) Transcranial pulsed ultrasound stimulates intact brain circuits. Neuron 66:681-694
78. Tyler WJ, Tufail Y, Finsterwald M, Tauchmann ML, Olson EJ, Majestic C (2008) Remote excitation of neuronal circuits using low-intensity, low-frequency ultrasound. PLoS One 3, e3511
79. Vignon F, Aubry JF, Tanter M, Margourn A, Fink M (2006) Adaptive focusing for transcranial ultrasound imaging using dual arrays. J Acoust Soc Am 120: 2737-2745
80. Vlachos F, Tung YS, Konofagou EE (2010) Permeability assessment of the focused ultrasound-induced blood-brain barrier opening using dynamic contrast-enhanced MRI. Phys Med Biol 55:5451-5466
81. Vlachos F, Tung YS, Konofagou E (2011) Permeability dependence study of the focused ultrasound-induced blood-brain barrier opening at distinct pressures and microbubble diameters using DCE-MRI. Mag Reson Med 66:821-830
82. White DN, Hanna LF (1974) Automatic midline echoencephalography. Examination of 3,333 consecutive cases with the automatic midline computer. Neurology 24:80-93
83. White DN, Clark JM, Chesebrough JN, White MN, Campbell JK (1968) Effect of the skull in degradingthe display of echoencephalographic B and C scans. J Acoust Soc Am 44:1339-1345
84. Xu Z, Owens G, Gordon D, Cain C, Ludomirsky A (2010) Noninvasive creation of an atrial septal defect by histotripsy in a canine model. Circulation 121:742-749
85. Xu Z, Carlson C, Beckelman B, Snell J, Eames M, Hanael A, Lopes B, Raghavan P, Lee CC, Yen CP, Schlesinger D, Aubry JF, Sheehan J (2014) Intracranial inertial cavitation threshold and thermal ablation lesion creation using magnetic resonance imaging-guided 220 kHz focused ultrasound surgery. J Neurosurg 7: 1-10
86. Yang PS, Kim H, Lee W, Bohlke M, Park S, Maher TJ, Yoo SS (2012) Transcranial focused ultrasound to the thalamus is associated with reduced extracellular GABA levels in rats. Neuropsychobiology 65: 153-160
87. Yoo SS, Bystritsky A, Lee JH, Zhang Y, Fischer K, Min BK, McDannold NJ, Pascual-Leone A, Jolesz FA (2011) Focused ultrasound modulates region-specifi c brain activity. Neuroimage 56:1267-1275
88. Younan Y, Deffi eux T, Larrat B, Fink M, Tanter M, Aubry JF (2013) Infl uence of the pressure fi eld distribution in transcranial ultrasonic neurostimulation. Med Phys 40:082902
89. Zhang F, Aravanis AM, Adamantidis A, de Lecea L, Deisseroth K (2007) Circuit-breakers: optical technologies for probing neural signals and systems. Nat Rev Neurosci 8:577-581
90. Zhang S, Ding T, Wan M, Jiang H, Yang X, Zhong H, Wang S (2011) Minimizing the thermal losses from perfusion during focused ultrasound exposures with fl owing microbubbles. J Acoust Soc Am 129: 2336-2344