Route to α-Aryl Phosphonoacetates: Useful Synthetic Precursors in the Horner-Wadsworth-Emmons Olefination

Journal of Organic Chemistry

Volumn 80, Issue 20, 2015, Pages 10288-10293

  Vangelder, Kelsey F ^a   Wang, Melinda ^a   Kozlowski, Marisa C ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ORGANIC COMPOUNDS;

ARYL BROMIDES; ARYL CHLORIDE; ARYLATIONS; SYNTHETIC PRECURSORS; WADSWORTH-EMMONS; WADSWORTH-EMMONS OLEFINATION;

CHEMICAL REACTIONS;

BROMIDE; BROMOBENZENE; CHLORIDE; CHLOROBENZENE; CYCLOPENTYL METHYL ETHER; DIMETHYL ETHER; ETHYL 2 (BENZOFURAN 5 YL) 2 (DIETHOXYPHOSPHORYL)ACETATE (ARYL BROMIDE); ETHYL 2 (DIETHOXYPHOSPHORYL) 2 (3 NITROPHENYL)ACETATE (ARYL BROMIDE); ETHYL 2 (DIETHOXYPHOSPHORYL) 2 (3,5 DIMETHYLPHENYL)ACETATE (ARYL BROMIDE); ETHYL 2 (DIETHOXYPHOSPHORYL) 2 (4 FLUOROPHENYL)ACETATE (ARYL CHLORIDE); ETHYL 2 (DIETHOXYPHOSPHORYL) 2 (4 METHOXYPHENYL)ACETATE (ARYL BROMIDE); ETHYL 2 (DIETHOXYPHOSPHORYL) 2 (NAPHTHALEN 2 YL)ACETATE (ARYL BROMIDE); ETHYL 2 (DIETHOXYPHOSPHORYL) 2 PHENYLACETATE (ARYL BROMIDE); ETHYL 2 (DIETHOXYPHOSPHORYL) 2 PHENYLACETATE (ARYL CHLORIDE); ETHYL 2 (DIETHOXYPHOSPHORYL) 2 [3 (TRIFLUOROMETHYL)PHENYL]ACETATE (ARYL BROMIDE); ETHYL 2 (DIETHOXYPHOSPHORYL) 2 [4 (TRIFLUOROMETHYL)PHENYL]ACETATE (ARYL CHLORIDE); ETHYL 2 [4 (1H PYRROL 1 YL)PHENYL] 2 (DIETHOXYPHOSPHORYL)ACETATE (ARYL CHLORIDE); HETEROCYCLIC COMPOUND; METHYL 4 [1 (DIETHOXYPHOSPHORYL) 2 ETHOXY 2 OXOETHYL]BENZOATE (ARYL BROMIDE); PHOSPHONOACETIC ACID; TERT BUTYL 5 [1 (DIETHOXYPHOSPHORYL) 2 ETHOXY 2 OXOETHYL] 1H INDOLE 1 CARBOXYLATE (ARYL CHLORIDE); UNCLASSIFIED DRUG; ALKENE;

ARBUZOV REACTION; ARTICLE; ARYLATION; CARBON BOND; CATALYSIS; CHEMICAL BOND; CROSS COUPLING REACTION; DRUG SYNTHESIS; ELECTROPHILICITY; HORNER WADSWORTH EMMONS REACTION; CHEMICAL STRUCTURE; CHEMISTRY; STEREOISOMERISM; SYNTHESIS;

ALKENES; CATALYSIS; HETEROCYCLIC COMPOUNDS; MOLECULAR STRUCTURE; PHOSPHONOACETIC ACID; STEREOISOMERISM;

EID: 84944937947     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/acs.joc.5b01887     Document Type: Article

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