Characterization of the biosynthetic gene cluster for maklamicin, a spirotetronate-class antibiotic of the endophytic Micromonospora sp. NBRC 110955

Microbiological Research

Volumn 180, Issue , 2015, Pages 30-39

  Daduang, Ratama ^a   Kitani, Shigeru ^a   Hashimoto, Junko ^b   Thamchaipenet, Arinthip ^c   Igarashi, Yasuhiro ^d   Shin ya, Kazuo ^b   Ikeda, Haruo ^e   Nihira, Takuya ^a,f  

^a OSAKA UNIVERSITY   (Japan)

^b Japan Biological Informatics Consortium   (Japan)

^c KASETSART UNIVERSITY   (Thailand)

^d TOYAMA PREFECTURAL UNIVERSITY   (Japan)

^e KITASATO UNIVERSITY   (Japan)

^f MAHIDOL UNIVERSITY   (Thailand)

Author keywords

Biosynthetic pathway; Maklamicin; Micromonospora; Polyketide compounds; Spirotetronate class antibiotics

Indexed keywords

ANTIBIOTICS; BACTERIA; BIOCHEMISTRY; GENES; KETONES;

ANTI-MICROBIAL ACTIVITY; BIOSYNTHETIC GENE CLUSTER; BIOSYNTHETIC PATHWAY; GRAM-POSITIVE BACTERIUM; MAKLAMICIN; MICROMONOSPORA; POLYKETIDE SYNTHASE GENES; POLYKETIDES;

BIOSYNTHESIS;

ANTIBIOTICS; ANTIMICROBIAL ACTIVITY; BACTERIUM; COMPARATIVE STUDY; ENDOPHYTE; GENE EXPRESSION; IDENTIFICATION METHOD; NUCLEIC ACID ANALYSIS; ORGANIC COMPOUND;

MICROMONOSPORA; MICROMONOSPORA SP.; POSIBACTERIA;

ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; MACROLIDE; MAKLAMICIN; POLYKETIDE SYNTHASE; PROTEIN SERINE THREONINE KINASE;

AMINO ACID SEQUENCE; BACTERIAL GENE; BIOSYNTHESIS; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MICROMONOSPORA; MOLECULAR CLONING; MOLECULAR GENETICS; MULTIGENE FAMILY; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BASE SEQUENCE; BIOSYNTHETIC PATHWAYS; CLONING, MOLECULAR; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; MACROLIDES; MICROMONOSPORA; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; OPEN READING FRAMES; POLYKETIDE SYNTHASES; PROTEIN-SERINE-THREONINE KINASES; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84944905351     PISSN: 09445013     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.micres.2015.07.003     Document Type: Article

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