29-Deoxymaklamicin, a new maklamicin analogue produced by a genetically engineered strain of Micromonospora sp. NBRC 110955

Journal of Bioscience and Bioengineering

Volumn 120, Issue 6, 2015, Pages 608-613

  Daduang, Ratama ^a   Kitani, Shigeru ^a   Sudoh, Yuri ^b   Grace Umadhay Pait, Ivy ^a   Thamchaipenet, Arinthip ^c   Ikeda, Haruo ^d   Igarashi, Yasuhiro ^e   Nihira, Takuya ^a,f  

^a OSAKA UNIVERSITY   (Japan)

^b HyphaGenesis Inc   (Japan)

^c KASETSART UNIVERSITY   (Thailand)

^d KITASATO UNIVERSITY   (Japan)

^e TOYAMA PREFECTURAL UNIVERSITY   (Japan)

^f MAHIDOL UNIVERSITY   (Thailand)

Author keywords

Cytochrome P450; Hydroxylation; Maklamicin; Micromonospora; Spirotetronate class antibiotics

Indexed keywords

ANTIBIOTICS; BACTERIA; BIOCHEMISTRY; GENES; HYDROXYLATION; KETONES; SUBSTRATES;

ANTI-MICROBIAL ACTIVITY; CYTOCHROME P450; CYTOCHROME P450 MONOOXYGENASES; GRAM-POSITIVE BACTERIUM; MAKLAMICIN; MICROMONOSPORA; POST POLYKETIDE SYNTHASE; STREPTOMYCES AVERMITILIS;

BIOSYNTHESIS;

29 DEOXYMAKLAMICIN; POLYKETIDE; UNCLASSIFIED DRUG; 29-DEOXYMAKLAMICIN; ANTIINFECTIVE AGENT; CYTOCHROME P450; MACROLIDE; MAKLAMICIN; POLYKETIDE SYNTHASE;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS CEREUS; BACILLUS SUBTILIS; CANDIDA ALBICANS; DRUG HYDROXYLATION; DRUG ISOLATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; GENE DELETION; MICROBIAL ACTIVITY; MICROCOCCUS LUTEUS; MICROMONOSPORA; NONHUMAN; NUCLEOTIDE SEQUENCE; STAPHYLOCOCCUS AUREUS; STREPTOMYCES AVERMITILIS; BIOSYNTHESIS; CHEMISTRY; DEFICIENCY; DRUG EFFECTS; GENETICS; GRAM POSITIVE BACTERIUM; HYDROXYLATION; METABOLISM; STREPTOMYCES;

ANTI-BACTERIAL AGENTS; BIOSYNTHETIC PATHWAYS; CYTOCHROME P-450 ENZYME SYSTEM; GRAM-POSITIVE BACTERIA; HYDROXYLATION; MACROLIDES; MICROMONOSPORA; POLYKETIDE SYNTHASES; STREPTOMYCES;

EID: 84946486196     PISSN: 13891723     EISSN: 13474421     Source Type: Journal    
DOI: 10.1016/j.jbiosc.2015.04.004     Document Type: Article

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