Effects of Transcription Elongation Rate and Xrn2 Exonuclease Activity on RNA Polymerase II Termination Suggest Widespread Kinetic Competition

Molecular Cell

Volumn 60, Issue 2, 2015, Pages 256-267

  Fong, Nova ^a   Brannan, Kristopher ^a   Erickson, Benjamin ^a   Kim, Hyunmin ^a   Cortazar, Michael A ^a   Sheridan, Ryan M ^a   Nguyen, Tram ^a   Karp, Shai ^a   Bentley, David L ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EXONUCLEASE; HISTONE; MUTANT PROTEIN; POLYADENYLIC ACID; PROTEIN; PROTEIN XRN2; RNA POLYMERASE II; SMALL NUCLEAR RNA; UNCLASSIFIED DRUG; EXORIBONUCLEASE; MESSENGER RNA; XRN2 PROTEIN, HUMAN;

ARTICLE; BINDING COMPETITION; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; ENZYME INACTIVATION; GENETIC TRANSCRIPTION; GENOME; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; POLYADENYLATION; PROTEIN EXPRESSION; TRANSCRIPTION ELONGATION; TRANSCRIPTION TERMINATION; BIOLOGICAL MODEL; CELL LINE; CYTOLOGY; EPITHELIUM CELL; GENETICS; HEK293 CELL LINE; HELA CELL LINE; HUMAN GENOME; KINETICS; LYMPHOCYTE; METABOLISM; MUTATION;

CELL LINE; EPITHELIAL CELLS; EXORIBONUCLEASES; GENOME, HUMAN; HEK293 CELLS; HELA CELLS; HUMANS; KINETICS; LYMPHOCYTES; MODELS, GENETIC; MUTATION; POLY A; RNA POLYMERASE II; RNA, MESSENGER; TRANSCRIPTION ELONGATION, GENETIC; TRANSCRIPTION TERMINATION, GENETIC;

EID: 84944887484     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2015.09.026     Document Type: Article

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